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Lista de obras de Peter C Fineran

Crystal structure of the anti-CRISPR repressor Aca2

publication published on 08 June 2021

High viral abundance and low diversity are associated with increased CRISPR-Cas prevalence across microbial ecosystems

publication published on 09 November 2021

A nucleus-forming jumbophage evades CRISPR-Cas DNA targeting but is vulnerable to type III RNA-based immunity

Assembly of multi-subunit fusion proteins into the RNA-targeting type III-D CRISPR-Cas effector complex

Author response: Type III CRISPR-Cas systems can provide redundancy to counteract viral escape from type I systems

CRISPR-Cas systems are widespread accessory elements across bacterial and archaeal plasmids

Cryo-EM micrographs of anti-CRISPR associated protein Aca2 bound to its RNA

Discovery of multiple anti-CRISPRs uncovers anti-defense gene clustering in mobile genetic elements

Diverse CRISPR-Cas complexes require independent translation of small and large subunits from a single gene

Global phylogeography and ancient evolution of the widespread human gut virus crAssphage

High viral abundance and low diversity are associated with increased CRISPR-Cas prevalence across microbial ecosystems

KatG inactivation generates vulnerabilities in isoniazid resistant strains ofMycobacterium tuberculosis

New antiviral defences are genetically embedded within prokaryotic immune systems

Phage defence system abundances vary across environments and increase with viral density

Type III CRISPR–Cas provides resistance against nucleus-forming jumbo phages via abortive infection

Variation at the common polysaccharide antigen locus drives lipopolysaccharide diversity within theP. syringaespecies complex

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