Lista de obras - Pascal Kienlen-Campard - Dominio Público Uruguay

A helix-to-coil transition at the epsilon-cut site in the transmembrane dimer of the amyloid precursor protein is required for proteolysis

scholarly article

A mouse model of familial amyotrophic lateral sclerosis expressing a mutant superoxide dismutase 1 shows evidence of disordered transport in the vasopressin hypothalamo-neurohypophysial axis

scientific article published on 01 December 1999

APP-dependent glial cell line-derived neurotrophic factor gene expression drives neuromuscular junction formation

artículo científico publicado en 2015

Activation of phagocytic activity in astrocytes by reduced expression of the inflammasome component ASC and its implication in a mouse model of Alzheimer disease

artículo científico publicado en 2016

Adenylosuccinate lyase deficiency: study of physiopathologic mechanism(s).

artículo científico publicado en 2004

Amyloid Precursor Protein (APP) controls the expression of the transcriptional activator Neuronal PAS Domain Protein 4 (NPAS4) and synaptic GABA release

artículo científico publicado en 2020

Amyloid precursor protein controls cholesterol turnover needed for neuronal activity

artículo científico publicado en 2013

Amyloidogenic processing but not amyloid precursor protein (APP) intracellular C-terminal domain production requires a precisely oriented APP dimer assembled by transmembrane GXXXG motifs

artículo científico publicado en 2008

Analysis by a highly sensitive split luciferase assay of the regions involved in APP dimerization and its impact on processing

artículo científico publicado en 2015

Characterization of Pterocarpus erinaceus kino extract and its gamma-secretase inhibitory properties.

artículo científico publicado en 2015

Conformational changes induced by the A21G Flemish mutation in the amyloid precursor protein lead to increased Aβ production

artículo científico publicado en 2014

Contribution of Kunitz Protease Inhibitor and Transmembrane Domains to Amyloid Precursor Protein Homodimerization

artículo científico publicado en 2012

Correlation between beta-amyloid peptide production and human APP-induced neuronal death

artículo científico publicado en 2002

Cortical cells reveal APP as a new player in the regulation of GABAergic neurotransmission

artículo científico publicado en 2017

Depolarization regulates cyclin D1 degradation and neuronal apoptosis: a hypothesis about the role of the ubiquitin/proteasome signalling pathway

artículo científico publicado en 1999

Epigenetic control of aquaporin 1 expression by the amyloid precursor protein

artículo científico publicado en 2009

Epigenetic induction of EGR-1 expression by the amyloid precursor protein during exposure to novelty

artículo científico publicado en 2013

Epigenetic regulations of immediate early genes expression involved in memory formation by the amyloid precursor protein of Alzheimer disease

artículo científico publicado en 2014

Expression of the c-ets1 gene in the hypothalamus and pituitary during rat development

scientific journal article

Failure of the interaction between presenilin 1 and the substrate of gamma-secretase to produce Abeta in insect cells

artículo científico publicado en 2002

Fe65 does not stabilize AICD during activation of transcription in a luciferase assay

artículo científico publicado en 2007

Gamma-secretase inhibitor activity of a Pterocarpus erinaceus extract

artículo científico publicado en 2013

Glucocorticoids, but not dopamine, negatively regulate the melanotrophic activity of the rabbit pituitary intermediate lobe

artículo científico publicado en 1994

Glycines from the APP GXXXG/GXXXA Transmembrane Motifs Promote Formation of Pathogenic Aβ Oligomers in Cells

artículo científico publicado en 2016

Heterotypic seeding of Tau fibrillization by pre-aggregated Abeta provides potent seeds for prion-like seeding and propagation of Tau-pathology in vivo

artículo científico publicado en 2016

How to Build and to Protect the Neuromuscular Junction: The Role of the Glial Cell Line-Derived Neurotrophic Factor

artículo científico publicado en 2020

In vitro screening on β-amyloid peptide production of plants used in traditional medicine for cognitive disorders

artículo científico publicado en 2010

Inhibitors of amyloid toxicity based on beta-sheet packing of Abeta40 and Abeta42.

artículo científico publicado en 2006

Intracellular amyloid-beta 1-42, but not extracellular soluble amyloid-beta peptides, induces neuronal apoptosis

artículo científico publicado en 2002

Lactacystin decreases amyloid-beta peptide production by inhibiting beta-secretase activity

artículo científico publicado en 2006

Lithium chloride increases the production of amyloid-beta peptide independently from its inhibition of glycogen synthase kinase 3.

artículo científico publicado en 2005

Pharmacological, molecular and functional characterization of vasoactive intestinal polypeptide/pituitary adenylate cyclase-activating polypeptide receptors in the rat pineal gland

artículo científico publicado en 1998

Phosphorylation of APP695 at Thr668 decreases gamma-cleavage and extracellular Abeta

artículo científico publicado en 2007

Presenilin transmembrane domain 8 conserved AXXXAXXXG motifs are required for the activity of the γ-secretase complex

artículo científico publicado en 2015

Sex-regulated gene dosage effect of PPARα on synaptic plasticity

article

Specificity of presenilin-1- and presenilin-2-dependent γ-secretases towards substrate processing.

artículo científico publicado en 2017

Structural features of the KPI domain control APP dimerization, trafficking, and processing

artículo científico publicado en 2011

Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo

artículo científico publicado en 2017

Tauopathy contributes to synaptic and cognitive deficits in a murine model for Alzheimer's disease

artículo científico publicado en 2014

Templated misfolding of Tau by prion-like seeding along neuronal connections impairs neuronal network function and associated behavioral outcomes in Tau transgenic mice

artículo científico publicado en 2015

What is the role of amyloid precursor protein dimerization?

artículo científico publicado en 2010

Lista de obras de Pascal Kienlen-Campard

A helix-to-coil transition at the epsilon-cut site in the transmembrane dimer of the amyloid precursor protein is required for proteolysis

A mouse model of familial amyotrophic lateral sclerosis expressing a mutant superoxide dismutase 1 shows evidence of disordered transport in the vasopressin hypothalamo-neurohypophysial axis

APP-dependent glial cell line-derived neurotrophic factor gene expression drives neuromuscular junction formation

Activation of phagocytic activity in astrocytes by reduced expression of the inflammasome component ASC and its implication in a mouse model of Alzheimer disease

Adenylosuccinate lyase deficiency: study of physiopathologic mechanism(s).

Amyloid Precursor Protein (APP) controls the expression of the transcriptional activator Neuronal PAS Domain Protein 4 (NPAS4) and synaptic GABA release

Amyloid precursor protein controls cholesterol turnover needed for neuronal activity

Amyloidogenic processing but not amyloid precursor protein (APP) intracellular C-terminal domain production requires a precisely oriented APP dimer assembled by transmembrane GXXXG motifs

Analysis by a highly sensitive split luciferase assay of the regions involved in APP dimerization and its impact on processing

Characterization of Pterocarpus erinaceus kino extract and its gamma-secretase inhibitory properties.

Conformational changes induced by the A21G Flemish mutation in the amyloid precursor protein lead to increased Aβ production

Contribution of Kunitz Protease Inhibitor and Transmembrane Domains to Amyloid Precursor Protein Homodimerization

Correlation between beta-amyloid peptide production and human APP-induced neuronal death

Cortical cells reveal APP as a new player in the regulation of GABAergic neurotransmission

Depolarization regulates cyclin D1 degradation and neuronal apoptosis: a hypothesis about the role of the ubiquitin/proteasome signalling pathway

Epigenetic control of aquaporin 1 expression by the amyloid precursor protein

Epigenetic induction of EGR-1 expression by the amyloid precursor protein during exposure to novelty

Epigenetic regulations of immediate early genes expression involved in memory formation by the amyloid precursor protein of Alzheimer disease

Expression of the c-ets1 gene in the hypothalamus and pituitary during rat development

Failure of the interaction between presenilin 1 and the substrate of gamma-secretase to produce Abeta in insect cells

Fe65 does not stabilize AICD during activation of transcription in a luciferase assay

Gamma-secretase inhibitor activity of a Pterocarpus erinaceus extract

Glucocorticoids, but not dopamine, negatively regulate the melanotrophic activity of the rabbit pituitary intermediate lobe

Glycines from the APP GXXXG/GXXXA Transmembrane Motifs Promote Formation of Pathogenic Aβ Oligomers in Cells

Heterotypic seeding of Tau fibrillization by pre-aggregated Abeta provides potent seeds for prion-like seeding and propagation of Tau-pathology in vivo

How to Build and to Protect the Neuromuscular Junction: The Role of the Glial Cell Line-Derived Neurotrophic Factor

In vitro screening on β-amyloid peptide production of plants used in traditional medicine for cognitive disorders

Inhibitors of amyloid toxicity based on beta-sheet packing of Abeta40 and Abeta42.

Intracellular amyloid-beta 1-42, but not extracellular soluble amyloid-beta peptides, induces neuronal apoptosis

Lactacystin decreases amyloid-beta peptide production by inhibiting beta-secretase activity

Lithium chloride increases the production of amyloid-beta peptide independently from its inhibition of glycogen synthase kinase 3.

Pharmacological, molecular and functional characterization of vasoactive intestinal polypeptide/pituitary adenylate cyclase-activating polypeptide receptors in the rat pineal gland

Phosphorylation of APP695 at Thr668 decreases gamma-cleavage and extracellular Abeta

Presenilin transmembrane domain 8 conserved AXXXAXXXG motifs are required for the activity of the γ-secretase complex

Sex-regulated gene dosage effect of PPARα on synaptic plasticity

Specificity of presenilin-1- and presenilin-2-dependent γ-secretases towards substrate processing.

Structural features of the KPI domain control APP dimerization, trafficking, and processing

Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo

Tauopathy contributes to synaptic and cognitive deficits in a murine model for Alzheimer's disease

Templated misfolding of Tau by prion-like seeding along neuronal connections impairs neuronal network function and associated behavioral outcomes in Tau transgenic mice

What is the role of amyloid precursor protein dimerization?