Lista de obras - Andrés F. Muro - Dominio Público Uruguay

A major fraction of fibronectin present in the extracellular matrix of tissues is plasma-derived.

artículo científico publicado en 2007

A polar mechanism coordinates different regions of alternative splicing within a single gene.

artículo científico publicado en 2005

A translationally optimized AAV-UGT1A1 vector drives safe and long-lasting correction of Crigler-Najjar syndrome

artículo científico publicado en 2016

Absence of regulated splicing of fibronectin EDA exon reduces atherosclerosis in mice.

artículo científico publicado en 2007

Age-dependent pattern of cerebellar susceptibility to bilirubin neurotoxicity in vivo in mice

artículo científico publicado en 2014

Albumin administration prevents neurological damage and death in a mouse model of severe neonatal hyperbilirubinemia.

artículo científico publicado en 2015

Alternative splicing of fibronectin: a mouse model demonstrates the identity of in vitro and in vivo systems and the processing autonomy of regulated exons in adult mice.

artículo científico publicado en 2004

An essential role for fibronectin extra type III domain A in pulmonary fibrosis.

artículo científico publicado en 2007

Attenuation of neuro-inflammation improves survival and neurodegeneration in a mouse model of severe neonatal hyperbilirubinemia.

artículo científico publicado en 2018

Beclin-1-mediated activation of autophagy improves proximal and distal urea cycle disorders

artículo científico publicado en 2020

Bilirubin-Induced Oxidative Stress Leads to DNA Damage in the Cerebellum of Hyperbilirubinemic Neonatal Mice and Activates DNA Double-Strand Break Repair Pathways in Human Cells

Brief Report: Alternative Splicing of Extra Domain A (EIIIA) of Fibronectin Plays a Tissue-Specific Role in Hematopoietic Homeostasis.

artículo científico publicado en 2016

CPEB2, CPEB3 and CPEB4 are coordinately regulated by miRNAs recognizing conserved binding sites in paralog positions of their 3'-UTRs

artículo científico publicado en 2010

Characterisation and chromosomal localisation of the rat alpha- and beta-adducin-encoding genes

scientific journal article

Characterization of the distal polyadenylation site of the ß-adducin (Add2) pre-mRNA.

artículo científico publicado en 2013

Control of fibroblast fibronectin expression and alternative splicing via the PI3K/Akt/mTOR pathway

artículo científico publicado en 2010

Coupling AAV-mediated promoterless gene targeting to SaCas9 nuclease to efficiently correct liver metabolic diseases

scientific article published on 18 June 2019

DNA sequencing by the chemical method: a 10 minute procedure for the G+A reaction

artículo científico publicado en 1993

EDA fibronectin-TLR4 axis sustains megakaryocyte expansion and inflammation in bone marrow fibrosis

artículo científico publicado en 2019

EDA-containing cellular fibronectin induces fibroblast differentiation through binding to alpha4beta7 integrin receptor and MAPK/Erk 1/2-dependent signaling

artículo científico publicado en 2010

EDA-containing fibronectin increases proliferation of embryonic stem cells

artículo científico publicado en 2013

Experimental models assessing bilirubin neurotoxicity

scientific article published on 07 September 2019

Extra domain-A fibronectin is necessary for the development of nasal remodeling in chronic allergen-induced rhinitis

artículo científico publicado en 2013

Fibronectin extra domain A stabilises atherosclerotic plaques in apolipoprotein E and in LDL-receptor-deficient mice.

artículo científico publicado en 2015

Fibronectin splice variants: understanding their multiple roles in health and disease using engineered mouse models.

scientific article published on July 2011

Generation of Ugt1-deficient murine liver cell lines using TALEN technology ⬇️

artículo científico publicado en 2014

Human liver stem cells express UGT1A1 and improve phenotype of immunocompromised Crigler Najjar syndrome type I mice

scientific article published on 21 January 2020

Hypertension in beta-adducin-deficient mice

artículo científico publicado en 2000

Hypertension-linked decrease in the expression of brain gamma-adducin

artículo científico publicado en 2002

Identification of 3' gene ends using transcriptional and genomic conservation across vertebrates

artículo científico publicado en 2012

Impaired motor coordination in mice lacking the EDA exon of the fibronectin gene.

artículo científico publicado en 2005

Impairment of enzymatic antioxidant defenses is associated with bilirubin-induced neuronal cell death in the cerebellum of Ugt1 KO mice

artículo científico publicado en 2015

Inflammatory signature of cerebellar neurodegeneration during neonatal hyperbilirubinemia in Ugt1 -/- mouse model.

artículo científico publicado en 2017

Lack of Fibronectin Extra Domain A Alternative Splicing Exacerbates Endothelial Dysfunction in Diabetes

artículo científico publicado en 2016

Life-long correction of hyperbilirubinemia with a neonatal liver-specific AAV-mediated gene transfer in a lethal mouse model of Crigler-Najjar Syndrome

artículo científico publicado en 2014

Long-distance regulation of Add2 pre-mRNA3'end processing

artículo científico publicado en 2013

Modulation of bilirubin neurotoxicity by the Abcb1 transporter in the Ugt1-/- lethal mouse model of neonatal hyperbilirubinemia.

artículo científico publicado en 2016

Preclinical Development of an AAV8-hUGT1A1 Vector for the Treatment of Crigler-Najjar Syndrome

scientific article published on 31 December 2018

Promoterless gene targeting without nucleases rescues lethality of a Crigler-Najjar syndrome mouse model

artículo científico publicado en 2017

Prothrombotic effects of fibronectin isoforms containing the EDA domain

artículo científico publicado en 2007

Regulated splicing of the fibronectin EDA exon is essential for proper skin wound healing and normal lifespan

scientific journal article

Regulation of fibronectin EDA exon alternative splicing: possible role of RNA secondary structure for enhancer display.

artículo científico publicado en 1999

Regulation of the fibronectin EDA exon alternative splicing. Cooperative role of the exonic enhancer element and the 5' splicing site

artículo científico publicado en 1998

Regulation of the human apolipoprotein AIV gene expression in transgenic mice

scientific article published on 01 February 1999

Repeated AAV-mediated gene transfer by serotype switching enables long-lasting therapeutic levels of hUgt1a1 enzyme in a mouse model of Crigler-Najjar Syndrome Type I.

artículo científico publicado en 2017

Stam2 expression pattern during embryo development

artículo científico publicado en 2011

TDP-43 regulates β-adducin (Add2) transcript stability.

artículo científico publicado en 2014

The CRE-binding factor ATF-2 facilitates the occupation of the CCAAT box in the fibronectin gene promoter

scientific article published on 01 July 1993

The erythrocyte skeletons of beta-adducin deficient mice have altered levels of tropomyosin, tropomodulin and EcapZ.

artículo científico publicado en 2004

The extra domain A of fibronectin is essential for allergen-induced airway fibrosis and hyperresponsiveness in mice

artículo científico publicado en 2010

Unexpected rescue of alpha-synuclein and multimerin1 deletion in C57BL/6JOlaHsd mice by beta-adducin knockout

artículo científico publicado en 2006

beta-adducin (Add2) KO mice show synaptic plasticity, motor coordination and behavioral deficits accompanied by changes in the expression and phosphorylation levels of the alpha- and gamma-adducin subunits

artículo científico publicado en 2009

Lista de obras de Andrés F. Muro

A major fraction of fibronectin present in the extracellular matrix of tissues is plasma-derived.

A polar mechanism coordinates different regions of alternative splicing within a single gene.

A translationally optimized AAV-UGT1A1 vector drives safe and long-lasting correction of Crigler-Najjar syndrome

Absence of regulated splicing of fibronectin EDA exon reduces atherosclerosis in mice.

Age-dependent pattern of cerebellar susceptibility to bilirubin neurotoxicity in vivo in mice

Albumin administration prevents neurological damage and death in a mouse model of severe neonatal hyperbilirubinemia.

Alternative splicing of fibronectin: a mouse model demonstrates the identity of in vitro and in vivo systems and the processing autonomy of regulated exons in adult mice.

An essential role for fibronectin extra type III domain A in pulmonary fibrosis.

Attenuation of neuro-inflammation improves survival and neurodegeneration in a mouse model of severe neonatal hyperbilirubinemia.

Beclin-1-mediated activation of autophagy improves proximal and distal urea cycle disorders

Bilirubin-Induced Oxidative Stress Leads to DNA Damage in the Cerebellum of Hyperbilirubinemic Neonatal Mice and Activates DNA Double-Strand Break Repair Pathways in Human Cells

Brief Report: Alternative Splicing of Extra Domain A (EIIIA) of Fibronectin Plays a Tissue-Specific Role in Hematopoietic Homeostasis.

CPEB2, CPEB3 and CPEB4 are coordinately regulated by miRNAs recognizing conserved binding sites in paralog positions of their 3'-UTRs

Characterisation and chromosomal localisation of the rat alpha- and beta-adducin-encoding genes

Characterization of the distal polyadenylation site of the ß-adducin (Add2) pre-mRNA.

Control of fibroblast fibronectin expression and alternative splicing via the PI3K/Akt/mTOR pathway

Coupling AAV-mediated promoterless gene targeting to SaCas9 nuclease to efficiently correct liver metabolic diseases

DNA sequencing by the chemical method: a 10 minute procedure for the G+A reaction

EDA fibronectin-TLR4 axis sustains megakaryocyte expansion and inflammation in bone marrow fibrosis

EDA-containing cellular fibronectin induces fibroblast differentiation through binding to alpha4beta7 integrin receptor and MAPK/Erk 1/2-dependent signaling

EDA-containing fibronectin increases proliferation of embryonic stem cells

Experimental models assessing bilirubin neurotoxicity

Extra domain-A fibronectin is necessary for the development of nasal remodeling in chronic allergen-induced rhinitis

Fibronectin extra domain A stabilises atherosclerotic plaques in apolipoprotein E and in LDL-receptor-deficient mice.

Fibronectin splice variants: understanding their multiple roles in health and disease using engineered mouse models.

Generation of Ugt1-deficient murine liver cell lines using TALEN technology ⬇️

Human liver stem cells express UGT1A1 and improve phenotype of immunocompromised Crigler Najjar syndrome type I mice

Hypertension in beta-adducin-deficient mice

Hypertension-linked decrease in the expression of brain gamma-adducin

Identification of 3' gene ends using transcriptional and genomic conservation across vertebrates

Impaired motor coordination in mice lacking the EDA exon of the fibronectin gene.

Impairment of enzymatic antioxidant defenses is associated with bilirubin-induced neuronal cell death in the cerebellum of Ugt1 KO mice

Inflammatory signature of cerebellar neurodegeneration during neonatal hyperbilirubinemia in Ugt1 -/- mouse model.

Lack of Fibronectin Extra Domain A Alternative Splicing Exacerbates Endothelial Dysfunction in Diabetes

Life-long correction of hyperbilirubinemia with a neonatal liver-specific AAV-mediated gene transfer in a lethal mouse model of Crigler-Najjar Syndrome

Long-distance regulation of Add2 pre-mRNA3'end processing

Modulation of bilirubin neurotoxicity by the Abcb1 transporter in the Ugt1-/- lethal mouse model of neonatal hyperbilirubinemia.

Preclinical Development of an AAV8-hUGT1A1 Vector for the Treatment of Crigler-Najjar Syndrome

Promoterless gene targeting without nucleases rescues lethality of a Crigler-Najjar syndrome mouse model

Prothrombotic effects of fibronectin isoforms containing the EDA domain

Regulated splicing of the fibronectin EDA exon is essential for proper skin wound healing and normal lifespan

Regulation of fibronectin EDA exon alternative splicing: possible role of RNA secondary structure for enhancer display.

Regulation of the fibronectin EDA exon alternative splicing. Cooperative role of the exonic enhancer element and the 5' splicing site

Regulation of the human apolipoprotein AIV gene expression in transgenic mice

Repeated AAV-mediated gene transfer by serotype switching enables long-lasting therapeutic levels of hUgt1a1 enzyme in a mouse model of Crigler-Najjar Syndrome Type I.

Stam2 expression pattern during embryo development

TDP-43 regulates β-adducin (Add2) transcript stability.

The CRE-binding factor ATF-2 facilitates the occupation of the CCAAT box in the fibronectin gene promoter

The erythrocyte skeletons of beta-adducin deficient mice have altered levels of tropomyosin, tropomodulin and EcapZ.

The extra domain A of fibronectin is essential for allergen-induced airway fibrosis and hyperresponsiveness in mice

Unexpected rescue of alpha-synuclein and multimerin1 deletion in C57BL/6JOlaHsd mice by beta-adducin knockout

beta-adducin (Add2) KO mice show synaptic plasticity, motor coordination and behavioral deficits accompanied by changes in the expression and phosphorylation levels of the alpha- and gamma-adducin subunits