Lista de obras - Robert M. Prins - Dominio Público Uruguay

2-Hydroxyglutarate Inhibits ATP Synthase and mTOR Signaling

artículo científico publicado en 2015

Advanced Age Increases Immunosuppression in the Brain and Decreases Immunotherapeutic Efficacy in Subjects with Glioblastoma

artículo científico publicado en 2020

An LXR agonist promotes glioblastoma cell death through inhibition of an EGFR/AKT/SREBP-1/LDLR-dependent pathway

artículo científico publicado en 2011

An essential requirement for the SCAP/SREBP signaling axis to protect cancer cells from lipotoxicity

artículo científico publicado en 2013

Anti-tumor activity and trafficking of self, tumor-specific T cells against tumors located in the brain

artículo científico publicado en 2008

Bioluminescent imaging of melanoma in live mice

artículo científico publicado en 2005

CD200 in CNS tumor-induced immunosuppression: the role for CD200 pathway blockade in targeted immunotherapy

artículo científico publicado en 2014

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

artículo científico publicado en 2009

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

artículo científico publicado en 2010

Cellular and vaccine therapeutic approaches for gliomas

artículo científico publicado en 2010

Central nervous system tumor immunity generated by a recombinant listeria monocytogenes vaccine targeting tyrosinase related protein-2 and real-time imaging of intracranial tumor burden.

artículo científico publicado en 2006

Characterization of defective CD4-CD8- T cells in murine tumors generated independent of antigen specificity

artículo científico publicado en 2004

Comparison of glioma-associated antigen peptide-loaded versus autologous tumor lysate-loaded dendritic cell vaccination in malignant glioma patients

artículo científico publicado en 2013

Contrasting effects of interleukin-2 secretion by rat glioma cells contingent upon anatomical location: accelerated tumorigenesis in the central nervous system and complete rejection in the periphery

artículo científico publicado en 2003

Correction to: First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma.

artículo científico publicado en 2018

Cytokine responsiveness of CD8(+) T cells is a reproducible biomarker for the clinical efficacy of dendritic cell vaccination in glioblastoma patients.

artículo científico publicado en 2014

Cytomegalovirus immunity after vaccination with autologous glioblastoma lysate.

artículo científico publicado en 2008

Cytotoxic T cells infiltrating a glioma express an aberrant phenotype that is associated with decreased function and apoptosis

artículo científico publicado en 2001

Decitabine immunosensitizes human gliomas to NY-ESO-1 specific T lymphocyte targeting through the Fas/Fas ligand pathway

artículo científico publicado en 2011

Dendritic cell vaccination in glioblastoma patients induces systemic and intracranial T-cell responses modulated by the local central nervous system tumor microenvironment

artículo científico publicado en 2005

Detection of 2-hydroxyglutaric acid in vivo by proton magnetic resonance spectroscopy in U87 glioma cells overexpressing isocitrate dehydrogenase-1 mutation

artículo científico publicado en 2012

Detection of immune responses after immunotherapy in glioblastoma using PET and MRI.

artículo científico publicado en 2017

EGFR signaling through an Akt-SREBP-1-dependent, rapamycin-resistant pathway sensitizes glioblastomas to antilipogenic therapy

artículo científico publicado en 2009

Efficacy of systemic adoptive transfer immunotherapy targeting NY-ESO-1 for glioblastoma

artículo científico publicado en 2015

Endogenous vaults and bioengineered vault nanoparticles for treatment of glioblastomas: implications for future targeted therapies

artículo científico publicado en 2012

Enhanced antitumor activity induced by adoptive T-cell transfer and adjunctive use of the histone deacetylase inhibitor LAQ824.

artículo científico publicado en 2009

Enhanced sensitivity to IL-2 signaling regulates the clinical responsiveness of IL-12-primed CD8(+) T cells in a melanoma model

artículo científico publicado en 2011

Epithelial membrane protein-2 (EMP2) promotes angiogenesis in glioblastoma multiforme

artículo científico publicado en 2017

Evidence for Innate and Adaptive Immune Responses in a Cohort of Intractable Pediatric Epilepsy Surgery Patients

article

First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma.

artículo científico publicado en 2018

Gene expression profile correlates with T-cell infiltration and relative survival in glioblastoma patients vaccinated with dendritic cell immunotherapy

artículo científico publicado en 2010

Identification of retinol binding protein 1 promoter hypermethylation in isocitrate dehydrogenase 1 and 2 mutant gliomas.

artículo científico publicado en 2012

Immunosensitization with a Bcl-2 small molecule inhibitor

artículo científico publicado en 2008

Immunosuppressive tumor-infiltrating myeloid cells mediate adaptive immune resistance via a PD-1/PD-L1 mechanism in glioblastoma.

artículo científico publicado en 2017

Immunotherapy for patients with malignant glioma: from theoretical principles to clinical applications

artículo científico publicado en 2006

Immunotherapy response assessment in neuro-oncology: a report of the RANO working group

artículo científico publicado en 2015

Implementing liquid biopsies into clinical decision making for cancer immunotherapy

artículo científico publicado en 2017

Irradiated tumor cell vaccine for treatment of an established glioma. I. Successful treatment with combined radiotherapy and cellular vaccination

artículo científico publicado en 2002

Irradiated tumor cell vaccine for treatment of an established glioma. II. Expansion of myeloid suppressor cells that promote tumor progression

artículo científico publicado en 2002

Lentiviral vectors with CMV or MHCII promoters administered in vivo: immune reactivity versus persistence of expression

artículo científico publicado en 2007

Metabolic characterization of human IDH mutant and wild type gliomas using simultaneous pH- and oxygen-sensitive molecular MRI

scientific article published on 04 May 2019

Monitoring of regulatory T cell frequencies and expression of CTLA-4 on T cells, before and after DC vaccination, can predict survival in GBM patients

artículo científico publicado en 2012

NIMG-56IMMUNOTHERAPY RESPONSE ASSESSMENT IN NEURO-ONCOLOGY (iRANO): A REPORT OF THE RANO WORKING GROUP.

artículo científico publicado en 2015

Neoadjuvant anti-PD-1 immunotherapy promotes a survival benefit with intratumoral and systemic immune responses in recurrent glioblastoma

article

Non-invasive detection of 2-hydroxyglutarate and other metabolites in IDH1 mutant glioma patients using magnetic resonance spectroscopy

artículo científico publicado en 2011

Quantitative PET reporter gene imaging of CD8+ T cells specific for a melanoma-expressed self-antigen

artículo científico publicado en 2008

Radial mobility and cytotoxic function of retroviral replicating vector transduced, non-adherent alloresponsive T lymphocytes.

artículo científico publicado en 2015

SPINT2 is hypermethylated in both IDH1 mutated and wild-type glioblastomas, and exerts tumor suppression via reduction of c-Met activation

scientific article published on 05 March 2019

The AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesis

artículo científico publicado en 2009

The histone deacetylase inhibitor, LBH589, promotes the systemic cytokine and effector responses of adoptively transferred CD8+ T cells

artículo científico publicado en 2014

Thymic function and output of recent thymic emigrant T cells during intracranial glioma progression

artículo científico publicado en 2003

Tissue microarray analysis for epithelial membrane protein-2 as a novel biomarker for gliomas.

artículo científico publicado en 2017

Tumor immunology, immunomics and targeted immunotherapy for central nervous system malignancies

artículo científico publicado en 2005

Tumor-suppressive miR148a is silenced by CpG island hypermethylation in IDH1-mutant gliomas.

artículo científico publicado en 2014

Validation of vessel size imaging (VSI) in high-grade human gliomas using magnetic resonance imaging, image-guided biopsies, and quantitative immunohistochemistry

artículo científico publicado en 2019

pH-weighted molecular imaging of gliomas using amine chemical exchange saturation transfer MRI

artículo científico publicado en 2015

Lista de obras de Robert M. Prins

2-Hydroxyglutarate Inhibits ATP Synthase and mTOR Signaling

Advanced Age Increases Immunosuppression in the Brain and Decreases Immunotherapeutic Efficacy in Subjects with Glioblastoma

An LXR agonist promotes glioblastoma cell death through inhibition of an EGFR/AKT/SREBP-1/LDLR-dependent pathway

An essential requirement for the SCAP/SREBP signaling axis to protect cancer cells from lipotoxicity

Anti-tumor activity and trafficking of self, tumor-specific T cells against tumors located in the brain

Bioluminescent imaging of melanoma in live mice

CD200 in CNS tumor-induced immunosuppression: the role for CD200 pathway blockade in targeted immunotherapy

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

Cellular and vaccine therapeutic approaches for gliomas

Central nervous system tumor immunity generated by a recombinant listeria monocytogenes vaccine targeting tyrosinase related protein-2 and real-time imaging of intracranial tumor burden.

Characterization of defective CD4-CD8- T cells in murine tumors generated independent of antigen specificity

Comparison of glioma-associated antigen peptide-loaded versus autologous tumor lysate-loaded dendritic cell vaccination in malignant glioma patients

Contrasting effects of interleukin-2 secretion by rat glioma cells contingent upon anatomical location: accelerated tumorigenesis in the central nervous system and complete rejection in the periphery

Correction to: First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma.

Cytokine responsiveness of CD8(+) T cells is a reproducible biomarker for the clinical efficacy of dendritic cell vaccination in glioblastoma patients.

Cytomegalovirus immunity after vaccination with autologous glioblastoma lysate.

Cytotoxic T cells infiltrating a glioma express an aberrant phenotype that is associated with decreased function and apoptosis

Decitabine immunosensitizes human gliomas to NY-ESO-1 specific T lymphocyte targeting through the Fas/Fas ligand pathway

Dendritic cell vaccination in glioblastoma patients induces systemic and intracranial T-cell responses modulated by the local central nervous system tumor microenvironment

Detection of 2-hydroxyglutaric acid in vivo by proton magnetic resonance spectroscopy in U87 glioma cells overexpressing isocitrate dehydrogenase-1 mutation

Detection of immune responses after immunotherapy in glioblastoma using PET and MRI.

EGFR signaling through an Akt-SREBP-1-dependent, rapamycin-resistant pathway sensitizes glioblastomas to antilipogenic therapy

Efficacy of systemic adoptive transfer immunotherapy targeting NY-ESO-1 for glioblastoma

Endogenous vaults and bioengineered vault nanoparticles for treatment of glioblastomas: implications for future targeted therapies

Enhanced antitumor activity induced by adoptive T-cell transfer and adjunctive use of the histone deacetylase inhibitor LAQ824.

Enhanced sensitivity to IL-2 signaling regulates the clinical responsiveness of IL-12-primed CD8(+) T cells in a melanoma model

Epithelial membrane protein-2 (EMP2) promotes angiogenesis in glioblastoma multiforme

Evidence for Innate and Adaptive Immune Responses in a Cohort of Intractable Pediatric Epilepsy Surgery Patients

First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma.

Gene expression profile correlates with T-cell infiltration and relative survival in glioblastoma patients vaccinated with dendritic cell immunotherapy

Identification of retinol binding protein 1 promoter hypermethylation in isocitrate dehydrogenase 1 and 2 mutant gliomas.

Immunosensitization with a Bcl-2 small molecule inhibitor

Immunosuppressive tumor-infiltrating myeloid cells mediate adaptive immune resistance via a PD-1/PD-L1 mechanism in glioblastoma.

Immunotherapy for patients with malignant glioma: from theoretical principles to clinical applications

Immunotherapy response assessment in neuro-oncology: a report of the RANO working group

Implementing liquid biopsies into clinical decision making for cancer immunotherapy

Irradiated tumor cell vaccine for treatment of an established glioma. I. Successful treatment with combined radiotherapy and cellular vaccination

Irradiated tumor cell vaccine for treatment of an established glioma. II. Expansion of myeloid suppressor cells that promote tumor progression

Lentiviral vectors with CMV or MHCII promoters administered in vivo: immune reactivity versus persistence of expression

Metabolic characterization of human IDH mutant and wild type gliomas using simultaneous pH- and oxygen-sensitive molecular MRI

Monitoring of regulatory T cell frequencies and expression of CTLA-4 on T cells, before and after DC vaccination, can predict survival in GBM patients

NIMG-56IMMUNOTHERAPY RESPONSE ASSESSMENT IN NEURO-ONCOLOGY (iRANO): A REPORT OF THE RANO WORKING GROUP.

Neoadjuvant anti-PD-1 immunotherapy promotes a survival benefit with intratumoral and systemic immune responses in recurrent glioblastoma

Non-invasive detection of 2-hydroxyglutarate and other metabolites in IDH1 mutant glioma patients using magnetic resonance spectroscopy

Quantitative PET reporter gene imaging of CD8+ T cells specific for a melanoma-expressed self-antigen

Radial mobility and cytotoxic function of retroviral replicating vector transduced, non-adherent alloresponsive T lymphocytes.

SPINT2 is hypermethylated in both IDH1 mutated and wild-type glioblastomas, and exerts tumor suppression via reduction of c-Met activation

The AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesis

The histone deacetylase inhibitor, LBH589, promotes the systemic cytokine and effector responses of adoptively transferred CD8+ T cells

Thymic function and output of recent thymic emigrant T cells during intracranial glioma progression

Tissue microarray analysis for epithelial membrane protein-2 as a novel biomarker for gliomas.

Tumor immunology, immunomics and targeted immunotherapy for central nervous system malignancies

Tumor-suppressive miR148a is silenced by CpG island hypermethylation in IDH1-mutant gliomas.

Validation of vessel size imaging (VSI) in high-grade human gliomas using magnetic resonance imaging, image-guided biopsies, and quantitative immunohistochemistry

pH-weighted molecular imaging of gliomas using amine chemical exchange saturation transfer MRI