Lista de obras - Brent R Copp - Dominio Público Uruguay

1,3-Dimethylguanine, a new purine from the new zealand ascidian botrylloides leachi

artículo científico publicado en 1999

1,3-dimethyl-8-oxoisoguanine, a new purine from the New Zealand ascidian Pseudodistoma cereum

artículo científico publicado en 2004

6-Bromoindolglyoxylamido derivatives as antimicrobial agents and antibiotic enhancers

artículo científico publicado en 2019

A Convenient New Route to 4-Substituted Benzo[de][3,6]Phenanthrolin-6(6H)-Ones: Important Intermediates in the Synthesis of Ring-A Analogues of the Cytotoxic Marine Alkaloid Ascididemin

artículo científico publicado en 1999

A Review of Fungal Protoilludane Sesquiterpenoid Natural Products

scientific article published on 19 December 2020

A Revised Structure and Assigned Absolute Configuration of Theissenolactone A

artículo científico publicado en 2020

A new biologically active malyngamide from a New Zealand collection of the sea hare Bursatella leachii

artículo científico publicado en 2002

AK37: the first pyridoacridine described capable of stabilizing the topoisomerase I cleavable complex

artículo científico publicado en 2004

Allantoin as A Biomarker of Inflammation in an Inflammatory Bowel Disease Mouse Model: NMR Analysis of Urine

scholarly article by Philippa A. Dryland et al published 3 June 2008 in The Open Bioactive Compounds Journal

An Acetylenic Lipid from the New Zealand Ascidian Pseudodistoma cereum: Exemplification of an Improved Workflow for Determination of Absolute Configuration of Long-Chain 2-Amino-3-alkanols

artículo científico publicado en 2019

Anti-inflammatory and antimalarial meroterpenoids from the New Zealand ascidian Aplidium scabellum

artículo científico publicado en 2011

Anti-inflammatory thiazine alkaloids isolated from the New Zealand ascidian Aplidium sp.: inhibitors of the neutrophil respiratory burst in a model of gouty arthritis

scientific article published on 11 May 2007

Antimalarial β-carbolines from the New Zealand ascidian Pseudodistoma opacum

artículo científico publicado en 2011

Antimicrobial Metabolites against Methicillin-Resistant Staphylococcus aureus from the Endophytic Fungus Neofusicoccum australe ⬇️

artículo científico

Antimicrobial Polyketide Metabolites from and

artículo científico publicado en 2021

Antimycobacterial natural products

artículo científico publicado en 2003

Antimycobacterial natural products: synthesis and preliminary biological evaluation of the oxazole-containing alkaloid texaline

Antiparasitic activity of marine pyridoacridone alkaloids related to the ascididemins

scientific article published on 01 June 2003

Bio-inspired dimerisation of prenylated quinones directed towards the synthesis of the meroterpenoid natural products, the scabellones

artículo científico publicado en 2015

Bioactive Aliphatic Sulfates from Marine Invertebrates

artículo científico publicado en 2019

Bioactive indole derivatives from the South Pacific marine sponges Rhopaloeides odorabile and Hyrtios sp ⬇️

artículo científico publicado en 2011

Bioinspired Syntheses of the Pyridoacridine Marine Alkaloids Demethyldeoxyamphimedine, Deoxyamphimedine, and Amphimedine

artículo científico publicado en 2015

Biologically Active Acetylenic Amino Alcohol and N-Hydroxylated 1,2,3,4-Tetrahydro-β-carboline Constituents of the New Zealand Ascidian Pseudodistoma opacum

artículo científico publicado en 2015

Biomimetic Synthesis of Thiaplidiaquinones A and B

artículo científico publicado en 2012

Chemical and biological explorations of the electrophilic reactivity of the bioactive marine natural product halenaquinone with biomimetic nucleophiles.

artículo científico publicado en 2010

Chemical discovery and global gene expression analysis in zebrafish

artículo científico publicado en 2003

Didemnidines A and B, Indole Spermidine Alkaloids from the New Zealand AscidianDidemnumsp

article

Discovery and evaluation of thiazinoquinones as anti-protozoal agents

artículo científico publicado en 2013

Discovery and preliminary structure-activity relationship analysis of 1,14-sperminediphenylacetamides as potent and selective antimalarial lead compounds

artículo científico publicado en 2012

Discovery and preliminary structure-activity relationship studies on tecomaquinone I and tectol as novel farnesyltransferase and plasmodial inhibitors

artículo científico publicado en 2016

Distomadines A and B, novel 6-hydroxyquinoline alkaloids from the New Zealand ascidian, Pseudodistoma aureum

artículo científico publicado en 2003

E/Z-rubrolide O, an anti-inflammatory halogenated furanone from the New Zealand ascidian Synoicum n. sp

scientific article published on 01 January 2007

Effect of common and experimental anti-tuberculosis treatments on Mycobacterium tuberculosis growing as biofilms

artículo científico publicado en 2016

Effect of common and experimental anti-tuberculosis treatments on Mycobacterium tuberculosis growing as biofilms

artículo científico publicado en 2016

Efficacy of a series of alpha-pyrone derivatives against Leishmania (L.) infantum and Trypanosoma cruzi.

artículo científico publicado en 2017

Enantiomeric 1,2,3-trithiane-containing alkaloids and two new 1,3-dithiane alkaloids from New Zealand ascidians.

artículo científico publicado en 2001

Enantiomeric Variability of Distaminolyne A. Refinement of ECD and NMR Methods for Determining Optical Purity of 1-Amino-2-Alkanols

Enantiomeric discorhabdin alkaloids and establishment of their absolute configurations using theoretical calculations of electronic circular dichroism spectra

artículo científico publicado en 2008

Epipyrone A, a Broad-Spectrum Antifungal Compound Produced by <i>Epicoccum nigrum</i> ICMP 19927

artículo científico publicado en 2020

Establishment of the absolute configuration of the bioactive marine alkaloid eudistomin X by stereospecific synthesis

Exploration of the Electrophilic Reactivity of the Cytotoxic Marine Alkaloid Discorhabdin C and Subsequent Discovery of a New Dimeric C-1/N-13-Linked Discorhabdin Natural Product

artículo científico publicado en 2020

Exploration of the antibiotic potentiating activity of indolglyoxylpolyamines

artículo científico publicado en 2019

Identification and characterization of chemically masked derivatives of pseudoephedrine, ephedrine, methamphetamine, and MDMA

artículo científico publicado en 2020

Identification of heteroarylenamines as a new class of antituberculosis lead molecules.

artículo científico publicado en 2005

Investigation of indolglyoxamide and indolacetamide analogues of polyamines as antimalarial and antitrypanosomal agents

artículo científico publicado en 2014

Investigation of the electrophilic reactivity of the biologically active marine sesquiterpenoid onchidal and model compounds

artículo científico publicado en 2018

Investigation of the electrophilic reactivity of the cytotoxic marine alkaloid discorhabdin B

artículo científico publicado en 2012

Isodiplamine, cystodytin K and lissoclinidine: novel bioactive alkaloids from the New Zealand ascidian Lissoclinum notti

scholarly article published by David R Appleton in 2003

Isolation and Characterization of Diastereomers of Discorhabdins H and K and Assignment of Absolute Configuration to Discorhabdins D, N, Q, S, T, and U

artículo científico publicado en 2010

Isolation and characterization of the new purine 1,3, 7-trimethylisoguanine from the New Zealand ascidian Pseudodistoma cereum

scientific article published on 01 August 2000

Isolation and stereospecific synthesis of janolusimide B from a New Zealand collection of the bryozoan Bugula flabellata

artículo científico publicado en 2014

Isolation of 2-(3'-bromo-4'-hydroxyphenol)ethanamine from the New Zealand ascidian Cnemidocarpa bicornuta

artículo científico publicado en 1998

Isolation of a Novel Polyketide from Neodidymelliopsis sp

artículo científico

Kottamides A-D: novel bioactive imidazolone-containing alkaloids from the New Zealand ascidian Pycnoclavella kottae.

artículo científico publicado en 2002

Marine natural products

artículo científico publicado en 2003

Marine natural products

artículo científico publicado en 2007

Marine natural products

artículo científico publicado en 2004

Marine natural products

artículo científico publicado en 2008

Marine natural products

artículo científico publicado en 2005

Marine natural products

scientific article published on 09 January 2006

Marine natural products

artículo científico publicado en 2010

Marine natural products

artículo científico publicado en 2010

Marine natural products

scientific article published on 22 December 2011

Marine natural products

artículo científico publicado en 2009

Marine natural products

scientific article published on 01 February 2013

Marine natural products

artículo científico publicado en 2015

Marine natural products

artículo científico publicado en 2014

Marine natural products

artículo científico publicado en 2016

Marine natural products

artículo científico publicado en 2017

Marine natural products

scientific article published on 01 February 2020

Marine natural products

artículo científico publicado en 2018

Marine natural products

scientific article published on 21 January 2019

Mechanism of ascididemin-induced cytotoxicity

artículo científico publicado en 2003

Naamidine A is an antagonist of the epidermal growth factor receptor and an in vivo active antitumor agent

artículo científico publicado en 1998

Natural and Synthetic Derivatives of Discorhabdin C, a Cytotoxic Pigment from the New Zealand Sponge Latrunculia cf. bocagei

scholarly article published by Brent R. Copp in 2005

Natural product growth inhibitors of Mycobacterium tuberculosis.

artículo científico publicado en 2006

Natural product inhibitors of fatty acid biosynthesis: synthesis of the marine microbial metabolites pseudopyronines A and B and evaluation of their anti-infective activities

New Psychoactive Substances Detected at the New Zealand Border, 2014 - 2018

article

New bioactive halenaquinone derivatives from South Pacific marine sponges of the genus Xestospongia

artículo científico publicado en 2010

Novel Adociaquinone Derivatives from the Indonesian Sponge Xestospongia sp.

artículo científico publicado en 2015

Novel cytotoxic topoisomerase II inhibiting pyrroloiminoquinones from Fijian sponges of the genus Zyzzya

scientific article published in 1993

Novel tryptophan-derived dipeptides and bioactive metabolites from the sea hare Aplysia dactylomela

artículo científico publicado en 2002

Orthidines A–E, tubastrine, 3,4-dimethoxyphenethyl-β-guanidine, and 1,14-sperminedihomovanillamide: potential anti-inflammatory alkaloids isolated from the New Zealand ascidian Aplidium orthium that act as inhibitors of neutrophil respiratory burst

artículo científico publicado en 2008

Potential anti-tumour compounds from marine sources ⬇️

1989 doctoral thesis by Brent R. Copp at University of Canterbury

Preclinical Evaluation of Discorhabdins in Antiangiogenic and Antitumor Models

scientific article published on 19 July 2018

Pyrroloiminoquinone and related metabolites from marine sponges

artículo científico publicado en 2005

Rapid synthesis of indole cis-enamides via hydroamidation of indolic alkynes

artículo científico publicado en 2013

Rossinones A and B, biologically active meroterpenoids from the Antarctic ascidian, Aplidium species

article

SAR and identification of 2-(quinolin-4-yloxy)acetamides as Mycobacterium tuberculosis cytochrome bc1 inhibitors

artículo científico publicado en 2016

Screening and Biological Effects of Marine Pyrroloiminoquinone Alkaloids: Potential Inhibitors of the HIF-1α/p300 Interaction.

artículo científico publicado en 2016

Semi-synthetic preparation of the rare, cytotoxic, deep-sea sourced sponge metabolites discorhabdins P and U

artículo científico publicado en 2006

Special Issue in Honor of Professors John W. Blunt and Murray H. G. Munro

artículo científico publicado en 2016

Spermine derivatives of indole-3-carboxylic acid, indole-3-acetic acid and indole-3-acrylic acid as Gram-negative antibiotic adjuvants

artículo científico publicado en 2020

Structure-Activity Relationships of the Bioactive Thiazinoquinone Marine Natural Products Thiaplidiaquinones A and B.

artículo científico publicado en 2015

Structure-activity relationship studies on thiaplidiaquinones A and B as novel inhibitors of Plasmodium falciparum and farnesyltransferase

artículo científico publicado en 2017

Styelsamines A−D: New Tetracyclic Pyridoacridine Alkaloids from the Indonesian AscidianEusynstyela latericius

Synthesis and Antibacterial Analysis of Analogues of the Marine Alkaloid Pseudoceratidine

artículo científico publicado en 2020

Synthesis and anti-inflammatory structure-activity relationships of thiazine-quinoline-quinones: inhibitors of the neutrophil respiratory burst in a model of acute gouty arthritis.

artículo científico publicado en 2008

Synthesis and antimalarial and antituberculosis activities of a series of natural and unnatural 4-methoxy-6-styryl-pyran-2-ones, dihydro analogues and photo-dimers

artículo científico publicado en 2012

Synthesis and antimalarial evaluation of artesunate-polyamine and trioxolane-polyamine conjugates.

artículo científico publicado en 2017

Synthesis and biological evaluation of the ascidian blood-pigment halocyamine A.

artículo científico publicado en 2017

Synthesis and in vitro and in vivo evaluation of antimalarial polyamines

artículo científico publicado en 2013

Synthesis of Hemitectol, Tectol, and Tecomaquinone I

artículo científico publicado en 2012

Synthesis of tunichrome Sp-1

artículo científico publicado en 2015

Synthesis, DNA binding and antitumor evaluation of styelsamine and cystodytin analogues.

artículo científico publicado en 2013

Technology for high-throughput screens: the present and future using zebrafish

artículo científico publicado en 2004

The Configuration of Distaminolyne A is S: Quantitative Evaluation of Exciton Coupling Circular Dichroism of N, O- Bis-arenoyl-1-amino-2-alkanols

artículo científico publicado en 2019

The transcriptional responses of Mycobacterium tuberculosis to inhibitors of metabolism: novel insights into drug mechanisms of action

artículo científico publicado en 2004

Total Synthesis of (-)-Bicubebin A, B, (+)-Bicubebin C and Structural Reassignment of (-)-cis-Cubebin

artículo científico publicado en 2017

Total synthesis of panicein A2.

artículo científico publicado en 2015

Whole organism approaches to chemical genomics: the promising role of zebrafish (Danio rerio).

artículo científico

Zebrafish: at the nexus of functional and chemical genomics

scientific article published on January 2006

Lista de obras de Brent R Copp

1,3-Dimethylguanine, a new purine from the new zealand ascidian botrylloides leachi

1,3-dimethyl-8-oxoisoguanine, a new purine from the New Zealand ascidian Pseudodistoma cereum

6-Bromoindolglyoxylamido derivatives as antimicrobial agents and antibiotic enhancers

A Convenient New Route to 4-Substituted Benzo[de][3,6]Phenanthrolin-6(6H)-Ones: Important Intermediates in the Synthesis of Ring-A Analogues of the Cytotoxic Marine Alkaloid Ascididemin

A Review of Fungal Protoilludane Sesquiterpenoid Natural Products

A Revised Structure and Assigned Absolute Configuration of Theissenolactone A

A new biologically active malyngamide from a New Zealand collection of the sea hare Bursatella leachii

AK37: the first pyridoacridine described capable of stabilizing the topoisomerase I cleavable complex

Allantoin as A Biomarker of Inflammation in an Inflammatory Bowel Disease Mouse Model: NMR Analysis of Urine

An Acetylenic Lipid from the New Zealand Ascidian Pseudodistoma cereum: Exemplification of an Improved Workflow for Determination of Absolute Configuration of Long-Chain 2-Amino-3-alkanols

Anti-inflammatory and antimalarial meroterpenoids from the New Zealand ascidian Aplidium scabellum

Anti-inflammatory thiazine alkaloids isolated from the New Zealand ascidian Aplidium sp.: inhibitors of the neutrophil respiratory burst in a model of gouty arthritis

Antimalarial β-carbolines from the New Zealand ascidian Pseudodistoma opacum

Antimicrobial Metabolites against Methicillin-Resistant Staphylococcus aureus from the Endophytic Fungus Neofusicoccum australe ⬇️

Antimicrobial Polyketide Metabolites from and

Antimycobacterial natural products

Antimycobacterial natural products: synthesis and preliminary biological evaluation of the oxazole-containing alkaloid texaline

Antiparasitic activity of marine pyridoacridone alkaloids related to the ascididemins

Bio-inspired dimerisation of prenylated quinones directed towards the synthesis of the meroterpenoid natural products, the scabellones

Bioactive Aliphatic Sulfates from Marine Invertebrates

Bioactive indole derivatives from the South Pacific marine sponges Rhopaloeides odorabile and Hyrtios sp ⬇️

Bioinspired Syntheses of the Pyridoacridine Marine Alkaloids Demethyldeoxyamphimedine, Deoxyamphimedine, and Amphimedine

Biologically Active Acetylenic Amino Alcohol and N-Hydroxylated 1,2,3,4-Tetrahydro-β-carboline Constituents of the New Zealand Ascidian Pseudodistoma opacum

Biomimetic Synthesis of Thiaplidiaquinones A and B

Chemical and biological explorations of the electrophilic reactivity of the bioactive marine natural product halenaquinone with biomimetic nucleophiles.

Chemical discovery and global gene expression analysis in zebrafish

Didemnidines A and B, Indole Spermidine Alkaloids from the New Zealand AscidianDidemnumsp

Discovery and evaluation of thiazinoquinones as anti-protozoal agents

Discovery and preliminary structure-activity relationship analysis of 1,14-sperminediphenylacetamides as potent and selective antimalarial lead compounds

Discovery and preliminary structure-activity relationship studies on tecomaquinone I and tectol as novel farnesyltransferase and plasmodial inhibitors

Distomadines A and B, novel 6-hydroxyquinoline alkaloids from the New Zealand ascidian, Pseudodistoma aureum

E/Z-rubrolide O, an anti-inflammatory halogenated furanone from the New Zealand ascidian Synoicum n. sp

Effect of common and experimental anti-tuberculosis treatments on Mycobacterium tuberculosis growing as biofilms

Effect of common and experimental anti-tuberculosis treatments on Mycobacterium tuberculosis growing as biofilms

Efficacy of a series of alpha-pyrone derivatives against Leishmania (L.) infantum and Trypanosoma cruzi.

Enantiomeric 1,2,3-trithiane-containing alkaloids and two new 1,3-dithiane alkaloids from New Zealand ascidians.

Enantiomeric Variability of Distaminolyne A. Refinement of ECD and NMR Methods for Determining Optical Purity of 1-Amino-2-Alkanols

Enantiomeric discorhabdin alkaloids and establishment of their absolute configurations using theoretical calculations of electronic circular dichroism spectra

Epipyrone A, a Broad-Spectrum Antifungal Compound Produced by <i>Epicoccum nigrum</i> ICMP 19927

Establishment of the absolute configuration of the bioactive marine alkaloid eudistomin X by stereospecific synthesis

Exploration of the Electrophilic Reactivity of the Cytotoxic Marine Alkaloid Discorhabdin C and Subsequent Discovery of a New Dimeric C-1/N-13-Linked Discorhabdin Natural Product

Exploration of the antibiotic potentiating activity of indolglyoxylpolyamines

Identification and characterization of chemically masked derivatives of pseudoephedrine, ephedrine, methamphetamine, and MDMA

Identification of heteroarylenamines as a new class of antituberculosis lead molecules.

Investigation of indolglyoxamide and indolacetamide analogues of polyamines as antimalarial and antitrypanosomal agents

Investigation of the electrophilic reactivity of the biologically active marine sesquiterpenoid onchidal and model compounds

Investigation of the electrophilic reactivity of the cytotoxic marine alkaloid discorhabdin B

Isodiplamine, cystodytin K and lissoclinidine: novel bioactive alkaloids from the New Zealand ascidian Lissoclinum notti

Isolation and Characterization of Diastereomers of Discorhabdins H and K and Assignment of Absolute Configuration to Discorhabdins D, N, Q, S, T, and U

Isolation and characterization of the new purine 1,3, 7-trimethylisoguanine from the New Zealand ascidian Pseudodistoma cereum

Isolation and stereospecific synthesis of janolusimide B from a New Zealand collection of the bryozoan Bugula flabellata

Isolation of 2-(3'-bromo-4'-hydroxyphenol)ethanamine from the New Zealand ascidian Cnemidocarpa bicornuta

Isolation of a Novel Polyketide from Neodidymelliopsis sp

Kottamides A-D: novel bioactive imidazolone-containing alkaloids from the New Zealand ascidian Pycnoclavella kottae.

Marine natural products

Marine natural products

Marine natural products

Marine natural products

Marine natural products

Marine natural products

Marine natural products

Marine natural products

Marine natural products

Marine natural products

Marine natural products

Marine natural products

Marine natural products

Marine natural products

Marine natural products

Marine natural products

Marine natural products

Marine natural products

Mechanism of ascididemin-induced cytotoxicity

Naamidine A is an antagonist of the epidermal growth factor receptor and an in vivo active antitumor agent

Natural and Synthetic Derivatives of Discorhabdin C, a Cytotoxic Pigment from the New Zealand Sponge Latrunculia cf. bocagei

Natural product growth inhibitors of Mycobacterium tuberculosis.

Natural product inhibitors of fatty acid biosynthesis: synthesis of the marine microbial metabolites pseudopyronines A and B and evaluation of their anti-infective activities

New Psychoactive Substances Detected at the New Zealand Border, 2014 - 2018

New bioactive halenaquinone derivatives from South Pacific marine sponges of the genus Xestospongia