Lista de obras - Eric J Huang - Dominio Público Uruguay

A developmental analysis of juxtavascular microglia dynamics and interactions with the vasculature

artículo científico publicado en 2020

A dramatic increase of C1q protein in the CNS during normal aging.

artículo científico publicado en 2013

ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects

artículo científico publicado en 2014

ALS-causative mutations in FUS/TLS confer gain and loss of function by altered association with SMN and U1-snRNP.

artículo científico publicado en 2015

Acetylation of tau inhibits its degradation and contributes to tauopathy

artículo científico publicado en 2010

Activity-dependent FUS dysregulation disrupts synaptic homeostasis

artículo científico publicado en 2014

Aldehyde dehydrogenase 1a1 mediates a GABA synthesis pathway in midbrain dopaminergic neurons.

artículo científico publicado en 2015

Amyloid vs FDG-PET in the differential diagnosis of AD and FTLD.

artículo científico publicado en 2011

An RNA interference screen identifies druggable regulators of MeCP2 stability.

artículo científico publicado en 2017

Argyrophilic grain disease differs from other tauopathies by lacking tau acetylation.

artículo científico publicado en 2013

Astrocyte layers in the mammalian cerebral cortex revealed by a single-cell in situ transcriptomic map

artículo científico publicado en 2020

Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination

artículo científico publicado en 2011

Axons take a dive: Specialized contacts of serotonergic axons with cells in the walls of the lateral ventricles in mice and humans

artículo científico publicado en 2014

Blocking the mitochondrial apoptotic pathway preserves motor neuron viability and function in a mouse model of amyotrophic lateral sclerosis

artículo científico publicado en 2010

Brn3a is a transcriptional regulator of soma size, target field innervation and axon pathfinding of inner ear sensory neurons

artículo científico publicado en 2001

CCR2 deficiency impairs macrophage infiltration and improves cognitive function after traumatic brain injury

artículo científico publicado en 2014

Clinico-pathological correlation in adenylate kinase 5 autoimmune limbic encephalitis

artículo científico publicado en 2015

Clinicopathological correlations in behavioural variant frontotemporal dementia.

artículo científico publicado en 2017

Clinicopathological correlations in corticobasal degeneration

artículo científico publicado en 2011

Comparative Healing of Surgical Incisions Created by the PEAK PlasmaBlade, Conventional Electrosurgery, and a Scalpel

scientific article published on 01 December 2009

Comparative healing of human cutaneous surgical incisions created by the PEAK PlasmaBlade, conventional electrosurgery, and a standard scalpel

artículo científico publicado en 2011

Comparative healing of rat fascia following incision with three surgical instruments

artículo científico publicado en 2011

Corridors of migrating neurons in the human brain and their decline during infancy.

artículo científico publicado en 2011

Deletion of Rbpj from postnatal endothelium leads to abnormal arteriovenous shunting in mice.

artículo científico publicado en 2014

Differential expression and processing of two cell associated forms of the kit-ligand: KL-1 and KL-2

artículo científico publicado en 1992

Direct phosphorylation and regulation of poly(ADP-ribose) polymerase-1 by extracellular signal-regulated kinases 1/2.

artículo científico publicado en 2006

Dissociation of frontotemporal dementia-related deficits and neuroinflammation in progranulin haploinsufficient mice

scientific article published on March 2013

Does Adult Neurogenesis Persist in the Human Hippocampus?

artículo científico publicado en 2018

Dopaminergic Neurons and Brain Reward Pathways: From Neurogenesis to Circuit Assembly.

artículo científico

Dysmyelination not demyelination causes neurological symptoms in preweaned mice in a murine model of Cockayne syndrome.

artículo científico publicado en 2012

Dysregulation of locus coeruleus development in congenital central hypoventilation syndrome

artículo científico publicado en 2015

Early vs late age at onset frontotemporal dementia and frontotemporal lobar degeneration

artículo científico publicado en 2018

Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons

artículo científico publicado en 2006

Evaluating and treating neurobehavioral symptoms in professional American football players: Lessons from a case series

artículo científico publicado en 2015

Existing Pittsburgh Compound-B positron emission tomography thresholds are too high: statistical and pathological evaluation

artículo científico publicado en 2015

Expression of A20 by dendritic cells preserves immune homeostasis and prevents colitis and spondyloarthritis.

artículo científico publicado en 2011

Expression of Trk receptors in the developing mouse trigeminal ganglion: in vivo evidence for NT-3 activation of TrkA and TrkB in addition to TrkC

scientific journal article

Extensive FUS-immunoreactive pathology in juvenile amyotrophic lateral sclerosis with basophilic inclusions

artículo científico publicado en 2010

Foxc1 is required by pericytes during fetal brain angiogenesis.

artículo científico publicado en 2013

HIPK2 represses beta-catenin-mediated transcription, epidermal stem cell expansion, and skin tumorigenesis

artículo científico publicado en 2007

HIPK2-Mediated Transcriptional Control of NMDA Receptor Subunit Expression Regulates Neuronal Survival and Cell Death

artículo científico publicado en 2018

Hipk2 cooperates with p53 to suppress γ-ray radiation-induced mouse thymic lymphoma

artículo científico publicado en 2011

Homeodomain-interacting protein kinase-2 regulates apoptosis in developing sensory and sympathetic neurons

artículo científico publicado en 2004

Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults

artículo científico publicado en 2018

Immature excitatory neurons develop during adolescence in the human amygdala

scientific article published on 21 June 2019

In vivo signatures of nonfluent/agrammatic primary progressive aphasia caused by FTLD pathology

artículo científico publicado en 2013

Increased apoptosis, p53 up-regulation, and cerebellar neuronal degeneration in repair-deficient Cockayne syndrome mice

artículo científico publicado en 2007

Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis.

artículo científico publicado en 2017

Inhibition of sphingolipid synthesis improves outcomes and survival in GARP mutant wobbler mice, a model of motor neuron degeneration

scientific article published on 28 April 2020

Interaction of Brn3a and HIPK2 mediates transcriptional repression of sensory neuron survival

scientific journal article

Interaction of FUS and HDAC1 regulates DNA damage response and repair in neurons.

artículo científico publicado en 2013

Interactions of Wnt/beta-catenin signaling and sonic hedgehog regulate the neurogenesis of ventral midbrain dopamine neurons

artículo científico publicado en 2010

Krüppel-like factor 15 activates hepatitis B virus gene expression and replication

artículo científico publicado en 2011

Lamin B1 mediates cell-autonomous neuropathology in a leukodystrophy mouse model

artículo científico publicado en 2013

Longitudinal tracking of neuronal mitochondria delineates PINK1/Parkin-dependent mechanisms of mitochondrial recycling and degradation

scientific article published in 2021

Loss of HIPK2 Protects Neurons from Mitochondrial Toxins by Regulating Parkin Protein Turnover

scientific article published on 27 November 2019

Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease

artículo científico publicado en 2017

Loss of mitochondrial fission depletes axonal mitochondria in midbrain dopamine neurons

artículo científico publicado en 2014

Loss of nuclear factor E2-related factor 1 in the brain leads to dysregulation of proteasome gene expression and neurodegeneration

artículo científico publicado en 2011

Massive CNS monocytic infiltration at autopsy in an alemtuzumab-treated patient with NMO.

artículo científico publicado en 2014

Mechanisms of FUS mutations in familial amyotrophic lateral sclerosis

artículo científico publicado en 2016

Modeling ALS and FTD with iPSC-derived neurons

artículo científico publicado en 2015

Multiple roles of beta-catenin in controlling the neurogenic niche for midbrain dopamine neurons.

artículo científico publicado en 2009

Murine knockin model for progranulin-deficient frontotemporal dementia with nonsense-mediated mRNA decay

artículo científico publicado en 2018

Myeloid expression of the AP-1 transcription factor JUNB modulates outcomes of type 1 and type 2 parasitic infections.

artículo científico publicado en 2015

NeuroD-null mice are deaf due to a severe loss of the inner ear sensory neurons during development

scientific journal article

Neuroimmune dysfunction in frontotemporal dementia: Insights from progranulin and C9orf72 deficiency

artículo científico publicado en 2022

Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency

scientific article published on 31 August 2020

Neurotrophins: roles in neuronal development and function

artículo científico publicado en 2001

Nonfluent/agrammatic PPA with in-vivo cortical amyloidosis and Pick's disease pathology

artículo científico publicado en 2013

Notch-1 activation and dendritic atrophy in prion disease

artículo científico publicado en 2005

Overexpression of vascular endothelial growth factor in the germinal matrix induces neurovascular proteases and intraventricular hemorrhage.

artículo científico publicado en 2013

Parallel states of pathological Wnt signaling in neonatal brain injury and colon cancer

artículo científico publicado en 2014

Postnatal growth of the human pons: a morphometric and immunohistochemical analysis.

artículo científico publicado en 2014

Practical utility of amyloid and FDG-PET in an academic dementia center

artículo científico publicado en 2013

Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation

artículo científico publicado en 2016

Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury

artículo científico publicado en 2012

Replication of hepatitis C virus RNA on autophagosomal membranes

artículo científico publicado en 2012

Role of dimerization of the membrane-associated growth factor kit ligand in juxtacrine signaling: the Sl17H mutation affects dimerization and stability-phenotypes in hematopoiesis.

artículo científico publicado en 1998

STAT3-mediated astrogliosis protects myelin development in neonatal brain injury

artículo científico publicado en 2012

Safety evaluation of AAV2-GDNF gene transfer into the dopaminergic nigrostriatal pathway in aged and parkinsonian rhesus monkeys

artículo científico publicado en 2009

Selective frontoinsular von Economo neuron and fork cell loss in early behavioral variant frontotemporal dementia

artículo científico publicado en 2011

Single-cell analysis of prenatal and postnatal human cortical development

artículo científico publicado en 2023

Species-dependent posttranscriptional regulation of NOS1 by FMRP in the developing cerebral cortex.

artículo científico publicado en 2012

Sporadic corticobasal syndrome due to FTLD-TDP.

artículo científico publicado en 2009

Targeted deletion of numb and numblike in sensory neurons reveals their essential functions in axon arborization

scientific journal article

Temporal and spatial requirements of Smoothened in ventral midbrain neuronal development

artículo científico publicado en 2013

The LC3-conjugation machinery specifies the loading of RNA-binding proteins into extracellular vesicles

scientific article published on 13 January 2020

The behavioural/dysexecutive variant of Alzheimer's disease: clinical, neuroimaging and pathological features

artículo científico publicado en 2015

The expression pattern of the c-kit ligand in gonads of mice supports a role for the c-kit receptor in oocyte growth and in proliferation of spermatogonia

artículo científico publicado en 1993

The hematopoietic growth factor KL is encoded by the Sl locus and is the ligand of the c-kit receptor, the gene product of the W locus

scientific journal article

The kit-ligand (steel factor) and its receptor c-kit/W: pleiotropic roles in gametogenesis and melanogenesis

artículo científico publicado en 1993

The murine steel panda mutation affects kit ligand expression and growth of early ovarian follicles

artículo científico publicado en 1993

Towards improved animal models of neonatal white matter injury associated with cerebral palsy.

artículo científico publicado en 2010

Transcriptional corepressors HIPK1 and HIPK2 control angiogenesis via TGF-β-TAK1-dependent mechanism

scientific journal article

Transgenic expression of entire hepatitis B virus in mice induces hepatocarcinogenesis independent of chronic liver injury

artículo científico publicado en 2011

Trk receptors: roles in neuronal signal transduction

artículo científico publicado en 2003

Typical and atypical pathology in primary progressive aphasia variants

artículo científico

Ventral midbrain dopaminergic neurons: From neurogenesis to neurodegeneration.

artículo científico publicado en 2015

c-kit receptor and ligand expression in postnatal development of the mouse cerebellum suggests a function for c-kit in inhibitory interneurons

artículo científico publicado en 1992

Lista de obras de Eric J Huang

A developmental analysis of juxtavascular microglia dynamics and interactions with the vasculature

A dramatic increase of C1q protein in the CNS during normal aging.

ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects

ALS-causative mutations in FUS/TLS confer gain and loss of function by altered association with SMN and U1-snRNP.

Acetylation of tau inhibits its degradation and contributes to tauopathy

Activity-dependent FUS dysregulation disrupts synaptic homeostasis

Aldehyde dehydrogenase 1a1 mediates a GABA synthesis pathway in midbrain dopaminergic neurons.

Amyloid vs FDG-PET in the differential diagnosis of AD and FTLD.

An RNA interference screen identifies druggable regulators of MeCP2 stability.

Argyrophilic grain disease differs from other tauopathies by lacking tau acetylation.

Astrocyte layers in the mammalian cerebral cortex revealed by a single-cell in situ transcriptomic map

Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination

Axons take a dive: Specialized contacts of serotonergic axons with cells in the walls of the lateral ventricles in mice and humans

Blocking the mitochondrial apoptotic pathway preserves motor neuron viability and function in a mouse model of amyotrophic lateral sclerosis

Brn3a is a transcriptional regulator of soma size, target field innervation and axon pathfinding of inner ear sensory neurons

CCR2 deficiency impairs macrophage infiltration and improves cognitive function after traumatic brain injury

Clinico-pathological correlation in adenylate kinase 5 autoimmune limbic encephalitis

Clinicopathological correlations in behavioural variant frontotemporal dementia.

Clinicopathological correlations in corticobasal degeneration

Comparative Healing of Surgical Incisions Created by the PEAK PlasmaBlade, Conventional Electrosurgery, and a Scalpel

Comparative healing of human cutaneous surgical incisions created by the PEAK PlasmaBlade, conventional electrosurgery, and a standard scalpel

Comparative healing of rat fascia following incision with three surgical instruments

Corridors of migrating neurons in the human brain and their decline during infancy.

Deletion of Rbpj from postnatal endothelium leads to abnormal arteriovenous shunting in mice.

Differential expression and processing of two cell associated forms of the kit-ligand: KL-1 and KL-2

Direct phosphorylation and regulation of poly(ADP-ribose) polymerase-1 by extracellular signal-regulated kinases 1/2.

Dissociation of frontotemporal dementia-related deficits and neuroinflammation in progranulin haploinsufficient mice

Does Adult Neurogenesis Persist in the Human Hippocampus?

Dopaminergic Neurons and Brain Reward Pathways: From Neurogenesis to Circuit Assembly.

Dysmyelination not demyelination causes neurological symptoms in preweaned mice in a murine model of Cockayne syndrome.

Dysregulation of locus coeruleus development in congenital central hypoventilation syndrome

Early vs late age at onset frontotemporal dementia and frontotemporal lobar degeneration

Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons

Evaluating and treating neurobehavioral symptoms in professional American football players: Lessons from a case series

Existing Pittsburgh Compound-B positron emission tomography thresholds are too high: statistical and pathological evaluation

Expression of A20 by dendritic cells preserves immune homeostasis and prevents colitis and spondyloarthritis.

Expression of Trk receptors in the developing mouse trigeminal ganglion: in vivo evidence for NT-3 activation of TrkA and TrkB in addition to TrkC

Extensive FUS-immunoreactive pathology in juvenile amyotrophic lateral sclerosis with basophilic inclusions

Foxc1 is required by pericytes during fetal brain angiogenesis.

HIPK2 represses beta-catenin-mediated transcription, epidermal stem cell expansion, and skin tumorigenesis

HIPK2-Mediated Transcriptional Control of NMDA Receptor Subunit Expression Regulates Neuronal Survival and Cell Death

Hipk2 cooperates with p53 to suppress γ-ray radiation-induced mouse thymic lymphoma

Homeodomain-interacting protein kinase-2 regulates apoptosis in developing sensory and sympathetic neurons

Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults

Immature excitatory neurons develop during adolescence in the human amygdala

In vivo signatures of nonfluent/agrammatic primary progressive aphasia caused by FTLD pathology

Increased apoptosis, p53 up-regulation, and cerebellar neuronal degeneration in repair-deficient Cockayne syndrome mice

Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis.

Inhibition of sphingolipid synthesis improves outcomes and survival in GARP mutant wobbler mice, a model of motor neuron degeneration

Interaction of Brn3a and HIPK2 mediates transcriptional repression of sensory neuron survival

Interaction of FUS and HDAC1 regulates DNA damage response and repair in neurons.

Interactions of Wnt/beta-catenin signaling and sonic hedgehog regulate the neurogenesis of ventral midbrain dopamine neurons

Krüppel-like factor 15 activates hepatitis B virus gene expression and replication

Lamin B1 mediates cell-autonomous neuropathology in a leukodystrophy mouse model

Longitudinal tracking of neuronal mitochondria delineates PINK1/Parkin-dependent mechanisms of mitochondrial recycling and degradation

Loss of HIPK2 Protects Neurons from Mitochondrial Toxins by Regulating Parkin Protein Turnover

Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease

Loss of mitochondrial fission depletes axonal mitochondria in midbrain dopamine neurons

Loss of nuclear factor E2-related factor 1 in the brain leads to dysregulation of proteasome gene expression and neurodegeneration

Massive CNS monocytic infiltration at autopsy in an alemtuzumab-treated patient with NMO.

Mechanisms of FUS mutations in familial amyotrophic lateral sclerosis

Modeling ALS and FTD with iPSC-derived neurons

Multiple roles of beta-catenin in controlling the neurogenic niche for midbrain dopamine neurons.

Murine knockin model for progranulin-deficient frontotemporal dementia with nonsense-mediated mRNA decay

Myeloid expression of the AP-1 transcription factor JUNB modulates outcomes of type 1 and type 2 parasitic infections.

NeuroD-null mice are deaf due to a severe loss of the inner ear sensory neurons during development

Neuroimmune dysfunction in frontotemporal dementia: Insights from progranulin and C9orf72 deficiency

Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency

Neurotrophins: roles in neuronal development and function

Nonfluent/agrammatic PPA with in-vivo cortical amyloidosis and Pick's disease pathology

Notch-1 activation and dendritic atrophy in prion disease

Overexpression of vascular endothelial growth factor in the germinal matrix induces neurovascular proteases and intraventricular hemorrhage.

Parallel states of pathological Wnt signaling in neonatal brain injury and colon cancer

Postnatal growth of the human pons: a morphometric and immunohistochemical analysis.

Practical utility of amyloid and FDG-PET in an academic dementia center

Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation

Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury

Replication of hepatitis C virus RNA on autophagosomal membranes

Role of dimerization of the membrane-associated growth factor kit ligand in juxtacrine signaling: the Sl17H mutation affects dimerization and stability-phenotypes in hematopoiesis.