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Lista de obras de Geoffrey D Holman

5-amino-imidazole carboxamide riboside increases glucose transport and cell-surface GLUT4 content in skeletal muscle from subjects with type 2 diabetes

artículo científico publicado en 2003

A common trafficking route for GLUT4 in cardiomyocytes in response to insulin, contraction and energy-status signalling

scientific article published on 10 February 2009

A common trafficking route for GLUT4 in cardiomyocytes in response to insulin, contraction and energy-status signalling

artículo científico publicado en 2009

A mechanism for the inhibitory effect of ethacrynate on fluid and electrolyte secretion in rabbit ileum [proceedings]

artículo científico publicado en 1977

A new class of sugar analogues for use in the investigation of sugar transport

artículo científico publicado en 1985

A new deadly Syn?

artículo científico publicado en 1999

AS160 phosphotyrosine-binding domain constructs inhibit insulin-stimulated GLUT4 vesicle fusion with the plasma membrane

scientific journal article

Alterted GLUT4 subcellular trafficking in primary cultures of rat adipocytes

artículo científico publicado en 1997

An allosteric pore model for sugar transport in human erythrocytes

artículo científico publicado en 1980

An explanation of the asymmetric binding of sugars to the human erythrocyte sugar-transport systems

artículo científico publicado el 1 de noviembre de 1973

Analysis of the structural features of the C-terminus of GLUT1 that are required for transport catalytic activity.

artículo científico publicado en 1995

Association of AP1 adaptor complexes with GLUT4 vesicles

scientific article published on 01 December 1999

Bath Breakfast Project (BBP)--examining the role of extended daily fasting in human energy balance and associated health outcomes: study protocol for a randomised controlled trial [ISRCTN31521726].

artículo científico publicado en 2011

Binding of cytochalasin B to trypsin and thermolysin fragments of the human erythrocyte hexose transporter

scientific article published on 01 September 1987

Blood-brain barrier glucose transporter: effects of hypo- and hyperglycemia revisited

artículo científico publicado en 1999

Cell biology of insulin action on glucose transport

artículo científico publicado en 1997

Cell surface accessibility of GLUT4 glucose transporters in insulin-stimulated rat adipose cells. Modulation by isoprenaline and adenosine

artículo científico publicado en 1992

Cell surface biotinylation of GLUT4.

artículo científico publicado en 1997

Cell-surface biotinylation of GLUT4 using bis-mannose photolabels

artículo científico publicado en 1998

Cell-surface labelling of glucose transporters in rat adipocytes

scientific article published on 01 October 1990

Cell-surface recognition of biotinylated membrane proteins requires very long spacer arms: an example from glucose-transporter probes

artículo científico publicado en 2001

Characterisation of glucose transport in the hyperthermophilic Archaeon Sulfolobus solfataricus

scientific article published on 01 June 1996

Chemical biology probes of mammalian GLUT structure and function

scholarly article by Geoffrey D Holman published in November 2018

Chronic insulin effects on insulin signalling and GLUT4 endocytosis are reversed by metformin

artículo científico publicado en 2000

Comparative effects of IGF-I and insulin on the glucose transporter system in rat muscle.

artículo científico publicado en 1994

Comparison of GLUT4 and GLUT1 subcellular trafficking in basal and insulin-stimulated 3T3-L1 cells.

artículo científico publicado en 1993

Contraction stimulates translocation of glucose transporter GLUT4 in skeletal muscle through a mechanism distinct from that of insulin

artículo científico publicado en 1995

Contraction-independent effects of catecholamines on glucose transport in isolated rat cardiomyocytes

artículo científico publicado en 1996

Contraction-stimulated muscle glucose transport and GLUT-4 surface content are dependent on glycogen content

artículo científico publicado en 1999

Cyclic AMP transport in human erythrocyte ghosts

artículo científico publicado el 21 de marzo de 1978

D-Fructose-L-sorbose interconversions. Access to 5-thio-D-fructose and interaction with the D-fructose transporter, GLUT5.

artículo científico publicado en 2001

D-galactose accumulation in rabbit ileum. Effects of theophylline on serosal permeability

artículo científico publicado el 17 de octubre de 1975

Deletion of both Rab-GTPase-activating proteins TBC14KO and TBC1D4 in mice eliminates insulin- and AICAR-stimulated glucose transport. Diabetes 2015;64:746-759

artículo científico publicado en 2015

Determination of the rates of appearance and loss of glucose transporters at the cell surface of rat adipose cells

artículo científico publicado en 1991

Development of an intracellular pool of glucose transporters in 3T3-L1 cells

artículo científico publicado en 1992

Development of high-affinity ligands and photoaffinity labels for the D-fructose transporter GLUT5.

artículo científico publicado en 2002

Distinct reading of different structural determinants modulates the dileucine-mediated transport steps of the lysosomal membrane protein LIMPII and the insulin-sensitive glucose transporter GLUT4.

artículo científico publicado en 2000

Effect of insulin on GLUT4 cell surface content and turnover rate in human skeletal muscle as measured by the exofacial bis-mannose photolabeling technique.

artículo científico publicado en 1997

Electrophysiological and electron-microscopical correlations with fluid and electrolyte secretion in rabbit ileum

artículo científico publicado el 1 de mayo de 1979

Emerging role for AS160/TBC1D4 and TBC1D1 in the regulation of GLUT4 traffic

artículo científico publicado en 2008

Endofacial competitive inhibition of glucose transporter-4 intrinsic activity by the mitogen-activated protein kinase inhibitor SB203580.

artículo científico publicado en 2005

Evidence against protein kinase B as a mediator of contraction-induced glucose transport and GLUT4 translocation in rat skeletal muscle

artículo científico publicado en 1998

Evidence for negative cooperativity in human erythrocyte sugar transport

artículo científico publicado en 1981

Evidence for two asymmetric conformational states in the human erythrocyte sugar-transport system

artículo científico publicado en 1975

Exofacial photolabelling of the human erythrocyte glucose transporter with an azitrifluoroethylbenzoyl-substituted bismannose.

artículo científico publicado en 1990

FGT-1 is the major glucose transporter in C. elegans and is central to aging pathways

artículo científico publicado en 2013

Fluid movements across rabbit ileum coupled to passive paracellular ion movements

artículo científico publicado el 1 de mayo de 1979

From receptor to transporter: insulin signalling to glucose transport.

artículo científico publicado en 1997

GLUT4 traffic through an ESCRT-III-dependent sorting compartment in adipocytes.

artículo científico publicado en 2012

GLUT4 translocation in human muscle strips

scientific article published on 01 August 1997

Galactose transport across the serosal border of rabbit ileum and its role in intracellular accumulation

artículo científico publicado en 1975

Glucose transporter localization in rat skeletal muscle. Autoradiographic study using ATB-[2-3H]BMPA photolabel

artículo científico publicado en 1994

Glut 4 content in the plasma membrane of rat skeletal muscle: comparative studies of the subcellular fractionation method and the exofacial photolabelling technique using ATB-BMPA

scientific article published on 01 September 1993

Growth factor-induced stimulation of hexose transport in 3T3-L1 adipocytes: evidence that insulin-induced translocation of GLUT4 is independent of activation of MAP kinase.

artículo científico publicado en 1994

Highly Potent and Isoform Selective Dual Site Binding Tankyrase/Wnt Signaling Inhibitors That Increase Cellular Glucose Uptake and Have Antiproliferative Activity.

artículo científico publicado en 2016

Homeostasis without a GLUT

artículo científico publicado el 14 de septiembre de 1995

Hydrogen bonding requirements for the insulin-sensitive sugar transport system of rat adipocytes

artículo científico publicado en 1981

Identification of Insulin-Activated Rab Proteins in Adipose Cells Using Bio-ATB-GTP Photolabeling Technique

artículo científico publicado en 2018

Identification of SNAP receptors in rat adipose cell membrane fractions and in SNARE complexes co-immunoprecipitated with epitope-tagged N-ethylmaleimide-sensitive fusion protein

artículo científico publicado en 1996

Identification of centaurin-alpha2: a phosphatidylinositide-binding protein present in fat, heart and skeletal muscle

artículo científico publicado en 2002

Identification of mammalian Vps24p as an effector of phosphatidylinositol 3,5-bisphosphate-dependent endosome compartmentalization

artículo científico publicado en 2003

Improvement in the properties of 3-phenyl-3-trifluoromethyldiazirine based photoreactive bis-glucose probes for GLUT4 following substitution on the phenyl ring

artículo científico publicado en 2002

In situ labelling of insulin stimulated GTP-binding proteins in adipocytes

artículo científico publicado en 1997

Infinite cis influx of cyclic AMP into human erythrocyte ghosts

artículo científico publicado el 2 de junio de 1979

Infusion of a biotinylated bis-glucose photolabel: a new method to quantify cell surface GLUT4 in the intact mouse heart

artículo científico publicado en 2007

Inhibition of internalization of glucose transporters and IGF-II receptors. Mechanism of action of MHC class I-derived peptides which augment the insulin response in rat adipose cells.

artículo científico publicado en 1993

Inhibition of the D-fructose transporter protein GLUT5 by fused-ring glyco-1,3-oxazolidin-2-thiones and -oxazolidin-2-ones

artículo científico publicado en 2003

Inhibition of the translocation of GLUT1 and GLUT4 in 3T3-L1 cells by the phosphatidylinositol 3-kinase inhibitor, wortmannin

artículo científico publicado en 1994

Insulin action in cultured human skeletal muscle cells during differentiation: assessment of cell surface GLUT4 and GLUT1 content.

artículo científico publicado en 2003

Insulin and contraction stimulate exocytosis, but increased AMP-activated protein kinase activity resulting from oxidative metabolism stress slows endocytosis of GLUT4 in cardiomyocytes

artículo científico publicado en 2004

Insulin and isoproterenol have opposing roles in the maintenance of cytosol pH and optimal fusion of GLUT4 vesicles with the plasma membrane

artículo científico publicado en 2002

Insulin regulates Rab3-Noc2 complex dissociation to promote GLUT4 translocation in rat adipocytes

artículo científico publicado en 2015

Insulin regulation of the two glucose transporters in 3T3-L1 adipocytes

artículo científico publicado en 1990

Insulin signaling meets vesicle traffic of GLUT4 at a plasma-membrane-activated fusion step.

artículo científico publicado en 2005

Insulin-sensitive regulation of glucose transport and GLUT4 translocation in skeletal muscle of GLUT1 transgenic mice

artículo científico publicado en 1999

Insulin-stimulated GLUT4 glucose transporter recycling. A problem in membrane protein subcellular trafficking through multiple pools.

artículo científico publicado en 1994

Insulin-stimulated cytosol alkalinization facilitates optimal activation of glucose transport in cardiomyocytes

scientific journal article

Insulinomimetic effect on glucose transport by epidermal growth factor when combined with a major histocompatibility complex class I-derived peptide.

artículo científico publicado en 1993

Interaction of hydrophobic bis (D-mannose) derivatives with adipocyte and erythrocyte sugar transport systems

scientific article published on 01 March 1985

Interleukin-3-mediated cell survival signals include phosphatidylinositol 3-kinase-dependent translocation of the glucose transporter GLUT1 to the cell surface

artículo científico publicado en 2003

Kinetic evidence for unique regulation of GLUT4 trafficking by insulin and AMP-activated protein kinase activators in L6 myotubes

artículo científico publicado en 2009

Kinetic resolution of the separate GLUT1 and GLUT4 glucose transport activities in 3T3-L1 cells

artículo científico publicado en 1992

Kinetics of GLUT4 trafficking in rat and human skeletal muscle

artículo científico publicado en 2009

Long-term metformin treatment stimulates cardiomyocyte glucose transport through an AMP-activated protein kinase-dependent reduction in GLUT4 endocytosis

artículo científico publicado en 2006

Metformin blocks downregulation of cell surface GLUT4 caused by chronic insulin treatment of rat adipocytes

artículo científico publicado en 1993

Molecular adaptations of adipose tissue to 6 weeks of morning fasting vs. daily breakfast consumption in lean and obese adults

artículo científico publicado en 2017

Muscling in on GLUT4 kinetics.

artículo científico publicado en 2010

Phosphatidylinositol 3-kinase acts at an intracellular membrane site to enhance GLUT4 exocytosis in 3T3-L1 cells

artículo científico publicado en 1996

Photolabeling of erythrocyte and adipocyte hexose transporters using a benzophenone derivative of bis(D-mannose).

artículo científico publicado en 1988

Physiological and molecular responses to an acute bout of reduced-exertion high-intensity interval training (REHIT).

artículo científico publicado en 2015

Proceedings: Accumulation of D-galactose at the serosal border of rabbit ileum: the effects of theophylline

artículo científico publicado en 1975

Proceedings: The role of Na as a determinant of asymmetric permeability of rabbit ileal brush-border to D-galactose

artículo científico publicado en 1974

Proteomic Analysis of GLUT4 Storage Vesicles Reveals Tumor Suppressor Candidate 5 (TUSC5) as a Novel Regulator of Insulin Action in Adipocytes

artículo científico publicado en 2015

Rab28 is a TBC1D1/TBC1D4 substrate involved in GLUT4 trafficking

artículo científico publicado en 2016

Reduced insulin-stimulated GLUT4 bioavailability in stroke-prone spontaneously hypertensive rats

artículo científico publicado en 2005

Regulating the motor for GLUT4 vesicle traffic

artículo científico publicado en 2008

Repeat treatment of obese mice with BRL 49653, a new potent insulin sensitizer, enhances insulin action in white adipocytes. Association with increased insulin binding and cell-surface GLUT4 as measured by photoaffinity labeling.

artículo científico publicado en 1995

Role of the nitric oxide pathway in AMPK-mediated glucose uptake and GLUT4 translocation in heart muscle

artículo científico publicado en 2004

Serine-294 and threonine-295 in the exofacial loop domain between helices 7 and 8 of glucose transporters (GLUT) are involved in the conformational alterations during the transport process.

artículo científico publicado en 1998

Side-specific analogues for the rat adipocyte sugar transport system

artículo científico publicado en 1982

Side-specific photolabelling of the hexose transporter

scientific article published on 01 June 1989

Spatial requirements for insulin-sensitive sugar transport in rat adipocytes

artículo científico publicado en 1981

Specificity and kinetics of hexose transport in Trypanosoma brucei

artículo científico publicado en 1989

Structural requirements for binding to the sugar-transport system of the human erythrocyte

artículo científico publicado en 1973

Structure, function and regulation of mammalian glucose transporters of the SLC2 family

artículo científico publicado en 2020

Subcellular localization and trafficking of the GLUT4 glucose transporter isoform in insulin-responsive cells.

artículo científico publicado en 1994

Subcellular trafficking kinetics of GLU4 mutated at the N- and C-terminal

artículo científico publicado en 1996

Substitution of tyrosine 293 of GLUT1 locks the transporter into an outward facing conformation

scientific article published on 01 April 1994

Sugar transport asymmetry in human erythrocytes--the effect of bulk haemoglobin removal and the addition of methylxanthines

artículo científico publicado en 1980

Symmetrical kinetic parameters for 3-O-methyl-D-glucose transport in adipocytes in the presence and in the absence of insulin

artículo científico publicado en 1981

Synthesis and evaluation of fructose analogues as inhibitors of the D-fructose transporter GLUT5.

artículo científico publicado en 2000

Synthesis of biotinylated bis(D-glucose) derivatives for glucose transporter photoaffinity labelling

artículo científico publicado en 2001

The causal role of breakfast in energy balance and health: a randomized controlled trial in lean adults

artículo científico publicado en 2014

The causal role of breakfast in energy balance and health: a randomized controlled trial in obese adults

artículo científico publicado en 2016

The effect of hexosamines on the active transport of sugars in the hamster

artículo científico publicado en 1971

The effects of removal of sodium ions from the mucosal solution on sugar absorption by rabbit ileum

scientific article published on 01 January 1976

The glucose transporter family: structure, function and tissue-specific expression.

artículo científico publicado en 1993

The human glomerular podocyte is a novel target for insulin action

artículo científico publicado en 2005

The role of Na as a determinant of the asymmetric permeability of rabbit ileal brush-border to D-galactose

artículo científico publicado en 1974

Theophylline-induced fluid and electrolyte sectetion by rabbit ileum results from negative anomalous osmotic flow across the tight-junction [proceedings]

artículo científico publicado en 1976

Thermal stability, storage and release of proteins with tailored fit in silica

artículo científico publicado en 2017

Thrifty Tbc1d1 and Tbc1d4 proteins link signalling and membrane trafficking pathways

artículo científico publicado en 2007

Trafficking of glucose transporters in 3T3-L1 cells. Inhibition of trafficking by phenylarsine oxide implicates a slow dissociation of transporters from trafficking proteins

artículo científico publicado el 1 de febrero de 1992

Translocation of the Na+/H+ exchanger 1 (NHE1) in cardiomyocyte responses to insulin and energy-status signalling

artículo científico publicado el 15 de diciembre de 2010

Transport of 3-O-methyl D-glucose and beta-methyl D-glucoside by rabbit ileum

artículo científico publicado en 1976

Transport of D-fructose and its analogues by Trypanosoma brucei

artículo científico publicado en 1993

Use of a novel impermeable biotinylated photolabeling reagent to assess insulin- and hypoxia-stimulated cell surface GLUT4 content in skeletal muscle from type 2 diabetic patients

artículo científico publicado en 2000

Use of bismannose photolabel to elucidate insulin-regulated GLUT4 subcellular trafficking kinetics in rat adipose cells. Evidence that exocytosis is a critical site of hormone action

artículo científico publicado en 1993

“Deletion of both Rab-GTPase–activating proteins TBC1D1 and TBC1D4 in mice eliminates insulin- and AICAR-stimulated glucose transport [corrected].

artículo científico publicado en 2014