Lista de obras - Elisabet Cuyàs - Dominio Público Uruguay

3,4-methylenedioxymethamphetamine induces gene expression changes in rats related to serotonergic and dopaminergic systems, but not to neurotoxicity

artículo científico publicado en 2013

5-HTTLPR polymorphism, mood disorders and MDMA use in a 3-year follow-up study

artículo científico publicado en 2010

A multiscale model of epigenetic heterogeneity-driven cell fate decision-making

artículo científico publicado en 2019

Accelerated geroncogenesis in hereditary breast-ovarian cancer syndrome

artículo científico publicado en 2016

Acquired resistance to metformin in breast cancer cells triggers transcriptome reprogramming toward a degradome-related metastatic stem-like profile

artículo científico publicado en 2014

Activation of the methylation cycle in cells reprogrammed into a stem cell-like state.

artículo científico publicado en 2015

Active transmembrane drug transport in microgravity: a validation study using an ABC transporter model.

artículo científico publicado en 2014

Anti-protozoal and anti-bacterial antibiotics that inhibit protein synthesis kill cancer subtypes enriched for stem cell-like properties

artículo científico publicado en 2015

BRCA1 haploinsufficiency cell-autonomously activates RANKL expression and generates denosumab-responsive breast cancer-initiating cells

artículo científico publicado en 2017

COMT val158met and 5-HTTLPR genetic polymorphisms moderate executive control in cannabis users.

artículo científico publicado en 2013

Cancer stem cell-driven efficacy of trastuzumab (Herceptin): towards a reclassification of clinically HER2-positive breast carcinomas

artículo científico publicado en 2015

Cell cycle regulation by the nutrient-sensing mammalian target of rapamycin (mTOR) pathway

artículo científico publicado en 2014

Clinical and therapeutic relevance of the metabolic oncogene fatty acid synthase in HER2+ breast cancer

artículo científico publicado en 2016

Clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy"): the influence of gender and genetics (CYP2D6, COMT, 5-HTT)

artículo científico publicado en 2012

Computer-aided discovery of biological activity spectra for anti-aging and anti-cancer olive oil oleuropeins

artículo científico publicado en 2014

Contribution of cytochrome P450 and ABCB1 genetic variability on methadone pharmacokinetics, dose requirements, and response

artículo científico publicado en 2011

EphA2 receptor activation with ephrin-A1 ligand restores cetuximab efficacy in NRAS-mutant colorectal cancer cells

artículo científico publicado en 2017

Epigenetic regulation of cell fate reprogramming in aging and disease: A predictive computational model.

artículo científico publicado en 2018

Epigenetics and nutrition-related epidemics of metabolic diseases: Current perspectives and challenges

artículo científico publicado en 2016

Errors and reproducibility of DNA array-based detection of allelic variants in ADME genes: PHARMAchip™

article

Exploring the Process of Energy Generation in Pathophysiology by Targeted Metabolomics: Performance of a Simple and Quantitative Method.

artículo científico publicado en 2015

Extra-virgin olive oil contains a metabolo-epigenetic inhibitor of cancer stem cells

artículo científico publicado en 2018

Genetics of Ecstasy (MDMA) Use

article

Germline BRCA1 mutation reprograms breast epithelial cell metabolism towards mitochondrial-dependent biosynthesis: evidence for metformin-based "starvation" strategies in BRCA1 carriers.

scientific article published on 31 May 2016

IGF-1R/epithelial-to-mesenchymal transition (EMT) crosstalk suppresses the erlotinib-sensitizing effect of EGFR exon 19 deletion mutations

artículo científico publicado en 2013

Metabolomic mapping of cancer stem cells for reducing and exploiting tumor heterogeneity

artículo científico publicado en 2017

Metabostemness: Metaboloepigenetic reprogramming of cancer stem-cell functions

artículo científico publicado en 2014

Metformin Potentiates the Benefits of Dietary Restraint: A Metabolomic Study.

artículo científico publicado en 2017

Metformin directly targets the H3K27me3 demethylase KDM6A/UTX

scientific article published on 08 May 2018

Metformin inhibits RANKL and sensitizes cancer stem cells to denosumab

artículo científico publicado en 2017

Metformin regulates global DNA methylation via mitochondrial one-carbon metabolism.

artículo científico publicado en 2017

Metformin targets histone acetylation in cancer-prone epithelial cells

artículo científico publicado en 2016

Mitophagy-driven mitochondrial rejuvenation regulates stem cell fate

scientific article published on 13 June 2016

Mitostemness

artículo científico publicado en 2018

Neurotoxic thioether adducts of 3,4-methylenedioxymethamphetamine identified in human urine after ecstasy ingestion

artículo científico publicado en 2009

Nuclear reprogramming of luminal-like breast cancer cells generates Sox2-overexpressing cancer stem-like cellular states harboring transcriptional activation of the mTOR pathway

artículo científico publicado en 2013

Nutritional Niches of Cancer Therapy-Induced Senescent Cells

scientific article published in 2022

Oncobiguanides: Paracelsus' law and nonconventional routes for administering diabetobiguanides for cancer treatment

artículo científico publicado en 2014

Oncometabolic Nuclear Reprogramming of Cancer Stemness

artículo científico publicado en 2016

Oncometabolic mutation IDH1 R132H confers a metformin-hypersensitive phenotype.

artículo científico publicado en 2015

Perfectionism dimensions in major postpartum depression

artículo científico publicado en 2011

Reprogramming of non-genomic estrogen signaling by the stemness factor SOX2 enhances the tumor-initiating capacity of breast cancer cells

artículo científico publicado en 2013

Response of brain metastasis from lung cancer patients to an oral nutraceutical product containing silibinin

artículo científico publicado en 2016

STAT3-targeted treatment with silibinin overcomes the acquired resistance to crizotinib in ALK-rearranged lung cancer

artículo científico publicado en 2016

Silibinin administration improves hepatic failure due to extensive liver infiltration in a breast cancer patient

article published in 2014

Silibinin meglumine, a water-soluble form of milk thistle silymarin, is an orally active anti-cancer agent that impedes the epithelial-to-mesenchymal transition (EMT) in EGFR-mutant non-small-cell lung carcinoma cells

artículo científico publicado en 2013

Silibinin suppresses EMT-driven erlotinib resistance by reversing the high miR-21/low miR-200c signature in vivo

scientific article published on January 2013

Stem cell-like ALDH(bright) cellular states in EGFR-mutant non-small cell lung cancer: a novel mechanism of acquired resistance to erlotinib targetable with the natural polyphenol silibinin

artículo científico publicado en 2013

Suppression of endogenous lipogenesis induces reversion of the malignant phenotype and normalized differentiation in breast cancer.

artículo científico publicado en 2016

Synthetic lethal interaction of cetuximab with MEK1/2 inhibition in NRAS-mutant metastatic colorectal cancer

artículo científico publicado en 2016

The Warburg effect version 2.0: metabolic reprogramming of cancer stem cells

artículo científico publicado en 2013

The anti-malarial chloroquine overcomes primary resistance and restores sensitivity to trastuzumab in HER2-positive breast cancer

artículo científico publicado en 2013

The consequences of 3,4-methylenedioxymethamphetamine induced CYP2D6 inhibition in humans

artículo científico publicado en 2008

The influence of 5-HTT and COMT genotypes on verbal fluency in ecstasy users

artículo científico

The influence of genetic and environmental factors among MDMA users in cognitive performance

artículo científico publicado en 2011

The nutritional phenome of EMT-induced cancer stem-like cells

artículo científico publicado en 2014

Topography studies on the membrane interaction mechanism of the eosinophil cationic protein.

artículo científico publicado en 2007

Xenopatients 2.0: reprogramming the epigenetic landscapes of patient-derived cancer genomes

artículo científico publicado en 2014

Lista de obras de Elisabet Cuyàs

3,4-methylenedioxymethamphetamine induces gene expression changes in rats related to serotonergic and dopaminergic systems, but not to neurotoxicity

5-HTTLPR polymorphism, mood disorders and MDMA use in a 3-year follow-up study

A multiscale model of epigenetic heterogeneity-driven cell fate decision-making

Accelerated geroncogenesis in hereditary breast-ovarian cancer syndrome

Acquired resistance to metformin in breast cancer cells triggers transcriptome reprogramming toward a degradome-related metastatic stem-like profile

Activation of the methylation cycle in cells reprogrammed into a stem cell-like state.

Active transmembrane drug transport in microgravity: a validation study using an ABC transporter model.

Anti-protozoal and anti-bacterial antibiotics that inhibit protein synthesis kill cancer subtypes enriched for stem cell-like properties

BRCA1 haploinsufficiency cell-autonomously activates RANKL expression and generates denosumab-responsive breast cancer-initiating cells

COMT val158met and 5-HTTLPR genetic polymorphisms moderate executive control in cannabis users.

Cancer stem cell-driven efficacy of trastuzumab (Herceptin): towards a reclassification of clinically HER2-positive breast carcinomas

Cell cycle regulation by the nutrient-sensing mammalian target of rapamycin (mTOR) pathway

Clinical and therapeutic relevance of the metabolic oncogene fatty acid synthase in HER2+ breast cancer

Clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy"): the influence of gender and genetics (CYP2D6, COMT, 5-HTT)

Computer-aided discovery of biological activity spectra for anti-aging and anti-cancer olive oil oleuropeins

Contribution of cytochrome P450 and ABCB1 genetic variability on methadone pharmacokinetics, dose requirements, and response

EphA2 receptor activation with ephrin-A1 ligand restores cetuximab efficacy in NRAS-mutant colorectal cancer cells

Epigenetic regulation of cell fate reprogramming in aging and disease: A predictive computational model.

Epigenetics and nutrition-related epidemics of metabolic diseases: Current perspectives and challenges

Errors and reproducibility of DNA array-based detection of allelic variants in ADME genes: PHARMAchip™

Exploring the Process of Energy Generation in Pathophysiology by Targeted Metabolomics: Performance of a Simple and Quantitative Method.

Extra-virgin olive oil contains a metabolo-epigenetic inhibitor of cancer stem cells

Genetics of Ecstasy (MDMA) Use

Germline BRCA1 mutation reprograms breast epithelial cell metabolism towards mitochondrial-dependent biosynthesis: evidence for metformin-based "starvation" strategies in BRCA1 carriers.

IGF-1R/epithelial-to-mesenchymal transition (EMT) crosstalk suppresses the erlotinib-sensitizing effect of EGFR exon 19 deletion mutations

Metabolomic mapping of cancer stem cells for reducing and exploiting tumor heterogeneity

Metabostemness: Metaboloepigenetic reprogramming of cancer stem-cell functions

Metformin Potentiates the Benefits of Dietary Restraint: A Metabolomic Study.

Metformin directly targets the H3K27me3 demethylase KDM6A/UTX

Metformin inhibits RANKL and sensitizes cancer stem cells to denosumab

Metformin regulates global DNA methylation via mitochondrial one-carbon metabolism.

Metformin targets histone acetylation in cancer-prone epithelial cells

Mitophagy-driven mitochondrial rejuvenation regulates stem cell fate

Mitostemness

Neurotoxic thioether adducts of 3,4-methylenedioxymethamphetamine identified in human urine after ecstasy ingestion

Nuclear reprogramming of luminal-like breast cancer cells generates Sox2-overexpressing cancer stem-like cellular states harboring transcriptional activation of the mTOR pathway

Nutritional Niches of Cancer Therapy-Induced Senescent Cells

Oncobiguanides: Paracelsus' law and nonconventional routes for administering diabetobiguanides for cancer treatment

Oncometabolic Nuclear Reprogramming of Cancer Stemness

Oncometabolic mutation IDH1 R132H confers a metformin-hypersensitive phenotype.

Perfectionism dimensions in major postpartum depression

Reprogramming of non-genomic estrogen signaling by the stemness factor SOX2 enhances the tumor-initiating capacity of breast cancer cells

Response of brain metastasis from lung cancer patients to an oral nutraceutical product containing silibinin

STAT3-targeted treatment with silibinin overcomes the acquired resistance to crizotinib in ALK-rearranged lung cancer

Silibinin administration improves hepatic failure due to extensive liver infiltration in a breast cancer patient

Silibinin meglumine, a water-soluble form of milk thistle silymarin, is an orally active anti-cancer agent that impedes the epithelial-to-mesenchymal transition (EMT) in EGFR-mutant non-small-cell lung carcinoma cells

Silibinin suppresses EMT-driven erlotinib resistance by reversing the high miR-21/low miR-200c signature in vivo

Stem cell-like ALDH(bright) cellular states in EGFR-mutant non-small cell lung cancer: a novel mechanism of acquired resistance to erlotinib targetable with the natural polyphenol silibinin

Suppression of endogenous lipogenesis induces reversion of the malignant phenotype and normalized differentiation in breast cancer.

Synthetic lethal interaction of cetuximab with MEK1/2 inhibition in NRAS-mutant metastatic colorectal cancer

The Warburg effect version 2.0: metabolic reprogramming of cancer stem cells

The anti-malarial chloroquine overcomes primary resistance and restores sensitivity to trastuzumab in HER2-positive breast cancer

The consequences of 3,4-methylenedioxymethamphetamine induced CYP2D6 inhibition in humans

The influence of 5-HTT and COMT genotypes on verbal fluency in ecstasy users

The influence of genetic and environmental factors among MDMA users in cognitive performance

The nutritional phenome of EMT-induced cancer stem-like cells

Topography studies on the membrane interaction mechanism of the eosinophil cationic protein.

Xenopatients 2.0: reprogramming the epigenetic landscapes of patient-derived cancer genomes