Lista de obras - Alvan C Hengge - Dominio Público Uruguay

A YopH PTP1B Chimera Shows the Importance of the WPD-Loop Sequence to the Activity, Structure, and Dynamics of Protein Tyrosine Phosphatases

artículo científico publicado en 2018

A comparison of phosphonothioic acids with phosphonic acids as phosphatase inhibitors.

artículo científico publicado en 2003

A concerted mechanism for the transfer of the thiophosphinoyl group from aryl dimethylphosphinothioate esters to oxyanionic nucleophiles in aqueous solution

artículo científico publicado en 2005

A mechanistic study of the alkaline hydrolysis of diaryl sulfate diesters

artículo científico publicado en 2004

Altered mechanisms of reactions of phosphate esters bridging a dinuclear metal center

artículo científico publicado en 2004

Altered transition state for the reaction of an RNA model catalyzed by a dinuclear zinc(II) catalyst

artículo científico publicado en 2008

An altered mechanism of hydrolysis for a metal-complexed phosphate diester.

artículo científico publicado en 2002

Chemistry and mechanism of phosphatases, diesterases and triesterases ⬇️

artículo científico publicado el 1 de enero de 2013

Comparison of the reaction progress of calcineurin with Mn2+ and Mg2+.

artículo científico publicado en 1999

Comparisons of phosphorothioate with phosphate transfer reactions for a monoester, diester, and triester: isotope effect studies

artículo científico publicado en 2003

Conformational motions regulate phosphoryl transfer in related protein tyrosine phosphatases.

artículo científico publicado en 2013

Conservative tryptophan mutants of the protein tyrosine phosphatase YopH exhibit impaired WPD-loop function and crystallize with divanadate esters in their active sites

artículo científico publicado en 2015

Diesterase activity and substrate binding in purple acid phosphatases

artículo científico publicado en 2007

Enzymatic mechanisms of phosphate and sulfate transfer.

artículo científico publicado en 2006

Examination of P-OR bridging bond orders in phosphate monoesters using (18)O isotope shifts in 31P NMR.

artículo científico publicado en 2005

Examination of the transition state of the low-molecular mass small tyrosine phosphatase 1. Comparisons with other protein phosphatases

artículo científico publicado en 1997

Impaired Acid Catalysis by Mutation of a Protein Loop Hinge Residue in a YopH Mutant Revealed by Crystal Structures

artículo científico publicado en 2009

Insights into the Phosphoryl Transfer Mechanism of Cyclin-Dependent Protein Kinases from ab Initio QM/MM Free-Energy Studies ⬇️

artículo científico publicado el 3 de noviembre de 2011

Isotope effect studies on the calcineurin phosphoryl-transfer reaction: transition state structure and effect of calmodulin and Mn2+.

artículo científico publicado en 1997

Isotope effects and medium effects on sulfuryl transfer reactions

artículo científico publicado en 2001

Kinetic Isotope Effects and Stereochemical Studies on a Ribonuclease Model: Hydrolysis Reactions of Uridine 3'-Nitrophenyl Phosphate

artículo científico publicado en 2000

Kinetic isotope effects for alkaline phosphatase reactions: implications for the role of active-site metal ions in catalysis

artículo científico publicado en 2007

Kinetic isotope effects in the characterization of catalysis by protein tyrosine phosphatases

artículo científico

Lanthanide Catalyzed Cyclization of Uridine 3'-p-Nitrophenyl Phosphate

scientific article published on 01 October 2000

Mechanism and transition state structure of aryl methylphosphonate esters doubly coordinated to a dinuclear cobalt(III) center

artículo científico publicado en 2009

Mechanism of rhodium-catalyzed carbene formation from diazo compounds

artículo científico publicado en 2007

Mechanistic Aspects of Phosphate Diester Cleavage Assisted by Imidazole. A Template Reaction for Obtaining Aryl Phosphoimidazoles.

artículo científico publicado en 2016

Mechanistic studies of protein tyrosine phosphatases YopH and Cdc25A with m-nitrobenzyl phosphate.

artículo científico publicado en 2004

Mechanistic study of protein phosphatase-1 (PP1), a catalytically promiscuous enzyme

artículo científico publicado en 2008

Metal ion catalyzed hydrolysis of ethyl p-nitrophenyl phosphate

artículo científico publicado en 2003

Metal-catalyzed phosphodiester cleavage: secondary 18O isotope effects as an indicator of mechanism

artículo científico publicado en 2006

Metavanadate at the active site of the phosphatase VHZ

artículo científico publicado en 2012

Mutation of Arg-166 of Alkaline Phosphatase Alters the Thio Effect but Not the Transition State for Phosphoryl Transfer. Implications for the Interpretation of Thio Effects in Reactions of Phosphatases†

artículo científico publicado en 2000

NMR data do not implicate a phosphorane in the T4 DNA ligase reaction

artículo científico publicado en 2008

Nature of the transition state of the protein-tyrosine phosphatase-catalyzed reaction ⬇️

artículo científico publicado el 31 de octubre de 1995

New functional aspects of the atypical protein tyrosine phosphatase VHZ.

artículo científico publicado en 2013

Probing potential medium effects on phosphate ester bonds using 18O isotope shifts on 31P NMR.

artículo científico publicado en 2005

Probing the origin of the compromised catalysis of E. coli alkaline phosphatase in its promiscuous sulfatase reaction

artículo científico publicado en 2007

Probing the transition-state structure of dual-specificity protein phosphatases using a physiological substrate mimic

artículo científico publicado en 2004

Role of protein conformational mobility in enzyme catalysis: acylation of alpha-chymotrypsin by specific peptide substrates

artículo científico publicado en 2004

Single Residue on the WPD-Loop Affects the pH Dependency of Catalysis in Protein Tyrosine Phosphatases

artículo científico publicado en 2021

Structural and Kinetic Properties of the Aldehyde Dehydrogenase NahF, a Broad Substrate Specificity Enzyme for Aldehyde Oxidation.

artículo científico publicado en 2016

Substrate-Promoted Formation of a Catalytically Competent Binuclear Center and Regulation of Reactivity in a Glycerophosphodiesterase from Enterobacter aerogenes

artículo científico publicado en 2008

The catalytic mechanism of Cdc25A phosphatase

artículo científico publicado en 2002

The divalent metal ion in the active site of uteroferrin modulates substrate binding and catalysis

artículo científico publicado en 2010

The effects of sulfur substitution for the nucleophile and bridging oxygen atoms in reactions of hydroxyalkyl phosphate esters

artículo científico publicado en 2008

The mechanism of the phosphoryl transfer catalyzed by Yersinia protein-tyrosine phosphatase: a computational and isotope effect study.

artículo científico publicado en 2001

The thermodynamics of phosphate versus phosphorothioate ester hydrolysis

artículo científico publicado en 2005

Thermodynamic origin of the increased rate of hydrolysis of phosphate and phosphorothioate esters in DMSO/water mixtures

artículo científico publicado en 2006

Transesterification thio effects of phosphate diesters: free energy barriers and kinetic and equilibrium isotope effects from density-functional theory

artículo científico publicado en 2006

Transition State Analysis of the Reaction Catalyzed by the Phosphotriesterase from Sphingobium sp. TCM1

artículo científico publicado en 2019

Transition States and Control of Substrate Preference in the Promiscuous Phosphatase PP1.

artículo científico publicado en 2017

Transition state analysis and requirement of Asp-262 general acid/base catalyst for full activation of dual-specificity phosphatase MKP3 by extracellular regulated kinase

artículo científico publicado en 2001

Transition state differences in hydrolysis reactions of alkyl versus aryl phosphate monoester monoanions.

artículo científico publicado en 2003

Transition state of the sulfuryl transfer reaction of estrogen sulfotransferase

scientific article published on 09 August 2006

Transition-State Interactions in a Promiscuous Enzyme: Sulfate and Phosphate Monoester Hydrolysis by Pseudomonas aeruginosa Arylsulfatase

scientific article published on 27 February 2019

Transition-state structures for the native dual-specific phosphatase VHR and D92N and S131A mutants. Contributions to the driving force for catalysis

artículo científico publicado en 1996

Lista de obras de Alvan C Hengge

A YopH PTP1B Chimera Shows the Importance of the WPD-Loop Sequence to the Activity, Structure, and Dynamics of Protein Tyrosine Phosphatases

A comparison of phosphonothioic acids with phosphonic acids as phosphatase inhibitors.

A concerted mechanism for the transfer of the thiophosphinoyl group from aryl dimethylphosphinothioate esters to oxyanionic nucleophiles in aqueous solution

A mechanistic study of the alkaline hydrolysis of diaryl sulfate diesters

Altered mechanisms of reactions of phosphate esters bridging a dinuclear metal center

Altered transition state for the reaction of an RNA model catalyzed by a dinuclear zinc(II) catalyst

An altered mechanism of hydrolysis for a metal-complexed phosphate diester.

Chemistry and mechanism of phosphatases, diesterases and triesterases ⬇️

Comparison of the reaction progress of calcineurin with Mn2+ and Mg2+.

Comparisons of phosphorothioate with phosphate transfer reactions for a monoester, diester, and triester: isotope effect studies

Conformational motions regulate phosphoryl transfer in related protein tyrosine phosphatases.

Conservative tryptophan mutants of the protein tyrosine phosphatase YopH exhibit impaired WPD-loop function and crystallize with divanadate esters in their active sites

Diesterase activity and substrate binding in purple acid phosphatases

Enzymatic mechanisms of phosphate and sulfate transfer.

Examination of P-OR bridging bond orders in phosphate monoesters using (18)O isotope shifts in 31P NMR.

Examination of the transition state of the low-molecular mass small tyrosine phosphatase 1. Comparisons with other protein phosphatases

Impaired Acid Catalysis by Mutation of a Protein Loop Hinge Residue in a YopH Mutant Revealed by Crystal Structures

Insights into the Phosphoryl Transfer Mechanism of Cyclin-Dependent Protein Kinases from ab Initio QM/MM Free-Energy Studies ⬇️

Isotope effect studies on the calcineurin phosphoryl-transfer reaction: transition state structure and effect of calmodulin and Mn2+.

Isotope effects and medium effects on sulfuryl transfer reactions

Kinetic Isotope Effects and Stereochemical Studies on a Ribonuclease Model: Hydrolysis Reactions of Uridine 3'-Nitrophenyl Phosphate

Kinetic isotope effects for alkaline phosphatase reactions: implications for the role of active-site metal ions in catalysis

Kinetic isotope effects in the characterization of catalysis by protein tyrosine phosphatases

Lanthanide Catalyzed Cyclization of Uridine 3'-p-Nitrophenyl Phosphate

Mechanism and transition state structure of aryl methylphosphonate esters doubly coordinated to a dinuclear cobalt(III) center

Mechanism of rhodium-catalyzed carbene formation from diazo compounds

Mechanistic Aspects of Phosphate Diester Cleavage Assisted by Imidazole. A Template Reaction for Obtaining Aryl Phosphoimidazoles.

Mechanistic studies of protein tyrosine phosphatases YopH and Cdc25A with m-nitrobenzyl phosphate.

Mechanistic study of protein phosphatase-1 (PP1), a catalytically promiscuous enzyme

Metal ion catalyzed hydrolysis of ethyl p-nitrophenyl phosphate

Metal-catalyzed phosphodiester cleavage: secondary 18O isotope effects as an indicator of mechanism

Metavanadate at the active site of the phosphatase VHZ

Mutation of Arg-166 of Alkaline Phosphatase Alters the Thio Effect but Not the Transition State for Phosphoryl Transfer. Implications for the Interpretation of Thio Effects in Reactions of Phosphatases†

NMR data do not implicate a phosphorane in the T4 DNA ligase reaction

Nature of the transition state of the protein-tyrosine phosphatase-catalyzed reaction ⬇️

New functional aspects of the atypical protein tyrosine phosphatase VHZ.

Probing potential medium effects on phosphate ester bonds using 18O isotope shifts on 31P NMR.

Probing the origin of the compromised catalysis of E. coli alkaline phosphatase in its promiscuous sulfatase reaction

Probing the transition-state structure of dual-specificity protein phosphatases using a physiological substrate mimic

Role of protein conformational mobility in enzyme catalysis: acylation of alpha-chymotrypsin by specific peptide substrates

Single Residue on the WPD-Loop Affects the pH Dependency of Catalysis in Protein Tyrosine Phosphatases

Structural and Kinetic Properties of the Aldehyde Dehydrogenase NahF, a Broad Substrate Specificity Enzyme for Aldehyde Oxidation.

Substrate-Promoted Formation of a Catalytically Competent Binuclear Center and Regulation of Reactivity in a Glycerophosphodiesterase from Enterobacter aerogenes

The catalytic mechanism of Cdc25A phosphatase

The divalent metal ion in the active site of uteroferrin modulates substrate binding and catalysis

The effects of sulfur substitution for the nucleophile and bridging oxygen atoms in reactions of hydroxyalkyl phosphate esters

The mechanism of the phosphoryl transfer catalyzed by Yersinia protein-tyrosine phosphatase: a computational and isotope effect study.

The thermodynamics of phosphate versus phosphorothioate ester hydrolysis

Thermodynamic origin of the increased rate of hydrolysis of phosphate and phosphorothioate esters in DMSO/water mixtures

Transesterification thio effects of phosphate diesters: free energy barriers and kinetic and equilibrium isotope effects from density-functional theory

Transition State Analysis of the Reaction Catalyzed by the Phosphotriesterase from Sphingobium sp. TCM1

Transition States and Control of Substrate Preference in the Promiscuous Phosphatase PP1.

Transition state analysis and requirement of Asp-262 general acid/base catalyst for full activation of dual-specificity phosphatase MKP3 by extracellular regulated kinase

Transition state differences in hydrolysis reactions of alkyl versus aryl phosphate monoester monoanions.

Transition state of the sulfuryl transfer reaction of estrogen sulfotransferase

Transition-State Interactions in a Promiscuous Enzyme: Sulfate and Phosphate Monoester Hydrolysis by Pseudomonas aeruginosa Arylsulfatase

Transition-state structures for the native dual-specific phosphatase VHR and D92N and S131A mutants. Contributions to the driving force for catalysis