Lista de obras - Eddie James - Dominio Público Uruguay

124 Heterogeneity of Allergen Epitope-specific CD4+ T Cells Responses: Steps Toward Optimal Composition for Peptide-based Immunotherapy

A Comparative Analysis of the Peptide Repertoires of HLA-DR Molecules Differentially Associated With Rheumatoid Arthritis.

artículo científico publicado en 2016

A Novel Approach of Identifying Immunodominant Self and Viral Antigen Cross-Reactive T Cells and Defining the Epitopes They Recognize

article

A Novel HLA-DRB1*10:01-Restricted T Cell Epitope From Citrullinated Type II Collagen Relevant to Rheumatoid Arthritis.

artículo científico publicado en 2015

A composite immune signature parallels disease progression across T1D subjects

scientific article published on 05 December 2019

An improved optical technique for monitoring plant cell concentration

scientific article published on 01 January 2000

Analysis of pancreatic beta cell specific CD4+ T cells reveals a predominance of proinsulin specific cells

scientific article published on 07 November 2018

Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes.

artículo científico publicado en 2016

Antigen-Specific CD4+ T Cells Recognize Epitopes of Protective Antigen following Vaccination with an Anthrax Vaccine.

artículo científico publicado en 2007

Antigen-specific immunomodulation for type 1 diabetes by novel recombinant antibodies directed against diabetes-associates auto-reactive T cell epitope

artículo científico publicado en 2013

Ara h 1-reactive T cells in individuals with peanut allergy

artículo científico publicado en 2011

Assessment of CD4+ T cell responses to glutamic acid decarboxylase 65 using DQ8 tetramers reveals a pathogenic role of GAD65 121-140 and GAD65 250-266 in T1D development

artículo científico publicado en 2014

Autoreactive CD4(+) T cells in patients with atopic dermatitis

artículo científico publicado en 2011

Beta cell-specific CD8+ T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes

scientific article published on 30 March 2020

CD4+ T cells from type 1 diabetic and healthy subjects exhibit different thresholds of activation to a naturally processed proinsulin epitope

artículo científico publicado en 2008

CD4+ T cells recognize diverse epitopes within GAD65: implications for repertoire development and diabetes monitoring.

artículo científico publicado en 2013

CD4+ T cells recognize unique and conserved 2009 H1N1 influenza hemagglutinin epitopes after natural infection and vaccination.

artículo científico publicado en 2013

CD8+ suppressor-mediated regulation of human CD4+ T cell responses to glutamic acid decarboxylase 65.

artículo científico publicado en 2007

Central T cell tolerance: Identification of tissue-restricted autoantigens in the thymus HLA-DR peptidome.

artículo científico publicado en 2015

Citrullinated Aggrecan Epitopes as Targets of Auto-reactive CD4+ T cells in Patients with Rheumatoid Arthritis

artículo científico publicado en 2019

Citrulline-specific Th1 cells are increased in rheumatoid arthritis and their frequency is influenced by disease duration and therapy

artículo científico publicado en 2014

Combinatorial detection of autoreactive CD8+ T cells with HLA-A2 multimers: a multi-centre study by the Immunology of Diabetes Society T Cell Workshop

artículo científico publicado en 2017

Comparison of cryopreservation methods on T-cell responses to islet and control antigens from type 1 diabetic patients and controls

artículo científico publicado en 2011

Corrigendum: Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes

artículo científico publicado en 2017

Corrigendum: Functional and Structural Characterization of a Novel HLA-DRB1*04:01-Restricted α-Enolase T Cell Epitope in Rheumatoid Arthritis

artículo científico publicado en 2017

DRB1*12:01 presents a unique subset of epitopes by preferring aromatics in pocket 9

artículo científico publicado en 2011

DRB4*01:01 Has a Distinct Motif and Presents a Proinsulin Epitope That Is Recognized in Subjects with Type 1 Diabetes

artículo científico publicado en 2018

Differences in self-peptide binding between T1D-related susceptible and protective DR4 subtypes ⬇️

artículo científico publicado el 22 de enero de 2011

Differential binding of pyruvate dehydrogenase complex-E2 epitopes by DRB108:01 and DRB111:01 Is predicted by their structural motifs and correlates with disease risk

artículo científico publicado en 2013

Differentiation stage determines pathologic and protective allergen-specific CD4+ T-cell outcomes during specific immunotherapy

artículo científico publicado en 2011

Direct Analysis of Insulin-Specific T Cells Provides New Insights

artículo científico publicado en 2017

Direct ex vivo analysis of allergen-specific CD4+ T cells

artículo científico publicado en 2010

Discriminative T cell recognition of cross-reactive islet-antigens is associated with HLA-DQ8 transdimer-mediated autoimmune diabetes

scientific article published on 21 August 2019

Dissecting mechanisms of immunodominance to the common tuberculosis antigens ESAT-6, CFP10, Rv2031c (hspX), Rv2654c (TB7.7), and Rv1038c (EsxJ)

artículo científico publicado en 2012

Expanding antigen-specific regulatory networks to treat autoimmunity

artículo científico publicado en 2016

FVIII proteins with a modified immunodominant T-cell epitope exhibit reduced immunogenicity and normal FVIII activity

artículo científico publicado en 2018

Factor VIII gene variants and inhibitor risk in African American hemophilia A patients

artículo científico publicado en 2015

Frequency of Epitope-Specific Naive CD4+ T Cells Correlates with Immunodominance in the Human Memory Repertoire ⬇️

artículo científico publicado el 10 de febrero de 2012

Functional and Structural Characterization of a Novel HLA-DRB1*04:01-Restricted α-Enolase T Cell Epitope in Rheumatoid Arthritis

artículo científico publicado en 2016

Functional islet-specific Treg can be generated from CD4+CD25- T cells of healthy and type 1 diabetic subjects

artículo científico publicado en 2009

Grass-specific CD4(+) T-cells exhibit varying degrees of cross-reactivity, implications for allergen-specific immunotherapy

artículo científico publicado en 2014

H5N1 strain-specific hemagglutinin CD4+ T cell epitopes restricted by HLA DR4.

artículo científico publicado en 2009

HLA-DR1001 presents "altered-self" peptides derived from joint-associated proteins by accepting citrulline in three of its binding pockets

artículo científico publicado en 2010

Human CD4+ T Cells Specific for Merkel Cell Polyomavirus Localize to Merkel Cell Carcinomas and Target a Required Oncogenic Domain

scientific article published on 12 August 2019

Human CD8⁺ and CD4⁺ T cell memory to lymphocytic choriomeningitis virus infection

artículo científico publicado en 2011

Human Leukocyte Antigen (HLA)-DRB115:01 and HLA-DRB501:01 Present Complementary Peptide Repertoires

artículo científico publicado en 2017

Identification of Unique Antigenic Determinants in the Amino Terminus of IA-2 (ICA512) in Childhood and Adult Autoimmune Diabetes: New Biomarker Development

artículo científico publicado en 2017

Immune Recognition of β-Cells: Neoepitopes as Key Players in the Loss of Tolerance

artículo científico publicado en 2018

Immune recognition of citrullinated epitopes

artículo científico publicado en 2016

Immunology of Diabetes Society T-Cell Workshop: HLA class I tetramer-directed epitope validation initiative T-Cell Workshop Report-HLA Class I Tetramer Validation Initiative

artículo científico publicado en 2011

Immunology of Diabetes Society T-Cell Workshop: HLA class II tetramer-directed epitope validation initiative.

artículo científico publicado en 2011

Increased islet antigen-specific regulatory and effector CD4+ T cells in healthy individuals with the type 1 diabetes-protective haplotype

artículo científico publicado en 2020

Inflammation-Induced Citrullinated Glucose-Regulated Protein 78 Elicits Immune Responses in Human Type 1 Diabetes

article

Islet-specific glucose-6-phosphatase catalytic subunit-related protein-reactive CD4+ T cells in human subjects.

artículo científico publicado en 2006

Lack of allergy to timothy grass pollen is not a passive phenomenon but associated with the allergen-specific modulation of immune reactivity

artículo científico publicado en 2015

Lineages of human T-cell clones, including T helper 17/T helper 1 cells, isolated at different stages of anti-factor VIII immune responses.

artículo científico publicado en 2009

Loss and recovery of protein productivity in genetically modified plant cell lines.

artículo científico publicado en 2006

Low-affinity major histocompatibility complex-binding peptides in type 1 diabetes.

artículo científico publicado en 2008

MHC II tetramers visualize human CD4+ T cell responses to Epstein-Barr virus infection and demonstrate atypical kinetics of the nuclear antigen EBNA1 response.

artículo científico publicado en 2013

Memory T cells in latent Mycobacterium tuberculosis infection are directed against three antigenic islands and largely contained in a CXCR3+CCR6+ Th1 subset

artículo científico publicado en 2013

Memory T cells specific to citrullinated α-enolase are enriched in the rheumatic joint

artículo científico publicado en 2018

Modifying Enzymes are Elicited by ER Stress, Generating Epitopes that are Selectively Recognized by CD4+ T Cells in Patients With Type 1 Diabetes.

artículo científico publicado en 2018

Modulation of CRTh2 expression on allergen-specific T cells following peptide immunotherapy

scientific article published on 07 June 2019

Multiplex mapping of CD4 T cell epitopes using class II tetramers

artículo científico publicado en 2006

Neuroinvasive West Nile Infection Elicits Elevated and Atypically Polarized T Cell Responses That Promote a Pathogenic Outcome

artículo científico publicado en 2016

Papillomavirus-specific CD4+ T cells exhibit reduced STAT-5 signaling and altered cytokine profiles in patients with recurrent respiratory papillomatosis

artículo científico publicado en 2011

Peanut-specific T cell responses in patients with different clinical reactivity

scientific article published in PLoS ONE

Peptide-MHC cellular microarray with innovative data analysis system for simultaneously detecting multiple CD4 T-cell responses

artículo científico publicado en 2010

Primary EBV Infection Induces an Acute Wave of Activated Antigen-Specific Cytotoxic CD4+ T Cells

artículo científico publicado en 2019

Production and characterization of biologically active human GM-CSF secreted by genetically modified plant cells

scientific article published on 01 June 2000

Protecting functional β cells with a therapeutic peptide

scientific article published on 01 September 2018

Rapid identification and expression of human TCRs in retrogenic mice

artículo científico publicado en 2016

Reassessing the role of HLA-DRB3 T-cell responses: evidence for significant expression and complementary antigen presentation.

artículo científico publicado en 2010

Recognition of posttranslationally modified GAD65 epitopes in subjects with type 1 diabetes.

artículo científico publicado en 2014

Searching immunodominant epitopes prior to epidemic: HLA class II-restricted SARS-CoV spike protein epitopes in unexposed individuals.

artículo científico publicado en 2008

Specific immunotherapy modifies allergen-specific CD4(+) T-cell responses in an epitope-dependent manner.

artículo científico publicado en 2013

Standardizing T-Cell Biomarkers in Type 1 Diabetes: Challenges and Recent Advances

scientific article published on 01 July 2019

Streamlined Single Cell TCR Isolation and Generation of Retroviral Vectors for In Vitro and In Vivo Expression of Human TCRs

artículo científico publicado en 2017

Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis.

artículo científico publicado en 2017

T cell epitopes and post-translationally modified epitopes in type 1 diabetes

artículo científico publicado en 2015

T cell immunity to Zika virus targets immunodominant epitopes that show cross-reactivity with other Flaviviruses.

artículo científico publicado en 2018

T cells from hemophilia A subjects recognize the same HLA-restricted FVIII epitope with a narrow TCR repertoire.

artículo científico publicado en 2016

T-Cell Epitopes and Neo-epitopes in Type 1 Diabetes: A Comprehensive Update and Reappraisal

scientific article published on 01 July 2020

T-cell responses in two unrelated hemophilia A inhibitor subjects include an epitope at the factor VIII R593C missense site.

artículo científico publicado en 2011

T-cell responses over time in a mild hemophilia A inhibitor subject: epitope identification and transient immunogenicity of the corresponding self-peptide

artículo científico publicado en 2007

Tetramer-guided epitope mapping reveals broad, individualized repertoires of tetanus toxin-specific CD4+ T cells and suggests HLA-based differences in epitope recognition

artículo científico publicado en 2007

The anthrax vaccine adsorbed vaccine generates protective antigen (PA)-Specific CD4+ T cells with a phenotype distinct from that of naive PA T cells

artículo científico publicado en 2008

The binding of antigenic peptides to HLA-DR is influenced by interactions between pocket 6 and pocket 9.

artículo científico publicado en 2009

The production of foreign proteins from genetically modified plant cells.

artículo científico publicado en 2001

Tumour and placenta establishment: The importance of antigen processing and presentation

artículo científico publicado en 2017

Uveitis-associated epitopes of retinal antigens are pathogenic in the humanized mouse model of uveitis and identify autoaggressive T cells

artículo científico publicado en 2011

Visualizing antigen specific CD4+ T cells using MHC class II tetramers

artículo científico publicado en 2009

Yellow fever vaccination elicits broad functional CD4+ T cell responses that recognize structural and nonstructural proteins

artículo científico publicado en 2013

β cell ER stress and the implications for immunogenicity in type 1 diabetes

artículo científico

Lista de obras de Eddie James

124 Heterogeneity of Allergen Epitope-specific CD4+ T Cells Responses: Steps Toward Optimal Composition for Peptide-based Immunotherapy

A Comparative Analysis of the Peptide Repertoires of HLA-DR Molecules Differentially Associated With Rheumatoid Arthritis.

A Novel Approach of Identifying Immunodominant Self and Viral Antigen Cross-Reactive T Cells and Defining the Epitopes They Recognize

A Novel HLA-DRB1*10:01-Restricted T Cell Epitope From Citrullinated Type II Collagen Relevant to Rheumatoid Arthritis.

A composite immune signature parallels disease progression across T1D subjects

An improved optical technique for monitoring plant cell concentration

Analysis of pancreatic beta cell specific CD4+ T cells reveals a predominance of proinsulin specific cells

Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes.

Antigen-Specific CD4+ T Cells Recognize Epitopes of Protective Antigen following Vaccination with an Anthrax Vaccine.

Antigen-specific immunomodulation for type 1 diabetes by novel recombinant antibodies directed against diabetes-associates auto-reactive T cell epitope

Ara h 1-reactive T cells in individuals with peanut allergy

Assessment of CD4+ T cell responses to glutamic acid decarboxylase 65 using DQ8 tetramers reveals a pathogenic role of GAD65 121-140 and GAD65 250-266 in T1D development

Autoreactive CD4(+) T cells in patients with atopic dermatitis

Beta cell-specific CD8+ T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes

CD4+ T cells from type 1 diabetic and healthy subjects exhibit different thresholds of activation to a naturally processed proinsulin epitope

CD4+ T cells recognize diverse epitopes within GAD65: implications for repertoire development and diabetes monitoring.

CD4+ T cells recognize unique and conserved 2009 H1N1 influenza hemagglutinin epitopes after natural infection and vaccination.

CD8+ suppressor-mediated regulation of human CD4+ T cell responses to glutamic acid decarboxylase 65.

Central T cell tolerance: Identification of tissue-restricted autoantigens in the thymus HLA-DR peptidome.

Citrullinated Aggrecan Epitopes as Targets of Auto-reactive CD4+ T cells in Patients with Rheumatoid Arthritis

Citrulline-specific Th1 cells are increased in rheumatoid arthritis and their frequency is influenced by disease duration and therapy

Combinatorial detection of autoreactive CD8+ T cells with HLA-A2 multimers: a multi-centre study by the Immunology of Diabetes Society T Cell Workshop

Comparison of cryopreservation methods on T-cell responses to islet and control antigens from type 1 diabetic patients and controls

Corrigendum: Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes

Corrigendum: Functional and Structural Characterization of a Novel HLA-DRB1*04:01-Restricted α-Enolase T Cell Epitope in Rheumatoid Arthritis

DRB1*12:01 presents a unique subset of epitopes by preferring aromatics in pocket 9

DRB4*01:01 Has a Distinct Motif and Presents a Proinsulin Epitope That Is Recognized in Subjects with Type 1 Diabetes

Differences in self-peptide binding between T1D-related susceptible and protective DR4 subtypes ⬇️

Differential binding of pyruvate dehydrogenase complex-E2 epitopes by DRB1*08:01 and DRB1*11:01 Is predicted by their structural motifs and correlates with disease risk

Differentiation stage determines pathologic and protective allergen-specific CD4+ T-cell outcomes during specific immunotherapy

Direct Analysis of Insulin-Specific T Cells Provides New Insights

Direct ex vivo analysis of allergen-specific CD4+ T cells

Discriminative T cell recognition of cross-reactive islet-antigens is associated with HLA-DQ8 transdimer-mediated autoimmune diabetes

Dissecting mechanisms of immunodominance to the common tuberculosis antigens ESAT-6, CFP10, Rv2031c (hspX), Rv2654c (TB7.7), and Rv1038c (EsxJ)

Expanding antigen-specific regulatory networks to treat autoimmunity

FVIII proteins with a modified immunodominant T-cell epitope exhibit reduced immunogenicity and normal FVIII activity

Factor VIII gene variants and inhibitor risk in African American hemophilia A patients

Frequency of Epitope-Specific Naive CD4+ T Cells Correlates with Immunodominance in the Human Memory Repertoire ⬇️

Functional and Structural Characterization of a Novel HLA-DRB1*04:01-Restricted α-Enolase T Cell Epitope in Rheumatoid Arthritis

Functional islet-specific Treg can be generated from CD4+CD25- T cells of healthy and type 1 diabetic subjects

Grass-specific CD4(+) T-cells exhibit varying degrees of cross-reactivity, implications for allergen-specific immunotherapy

H5N1 strain-specific hemagglutinin CD4+ T cell epitopes restricted by HLA DR4.

HLA-DR1001 presents "altered-self" peptides derived from joint-associated proteins by accepting citrulline in three of its binding pockets

Human CD4+ T Cells Specific for Merkel Cell Polyomavirus Localize to Merkel Cell Carcinomas and Target a Required Oncogenic Domain

Human CD8⁺ and CD4⁺ T cell memory to lymphocytic choriomeningitis virus infection

Human Leukocyte Antigen (HLA)-DRB1*15:01 and HLA-DRB5*01:01 Present Complementary Peptide Repertoires

Identification of Unique Antigenic Determinants in the Amino Terminus of IA-2 (ICA512) in Childhood and Adult Autoimmune Diabetes: New Biomarker Development

Immune Recognition of β-Cells: Neoepitopes as Key Players in the Loss of Tolerance

Immune recognition of citrullinated epitopes

Immunology of Diabetes Society T-Cell Workshop: HLA class I tetramer-directed epitope validation initiative T-Cell Workshop Report-HLA Class I Tetramer Validation Initiative

Immunology of Diabetes Society T-Cell Workshop: HLA class II tetramer-directed epitope validation initiative.

Increased islet antigen-specific regulatory and effector CD4+ T cells in healthy individuals with the type 1 diabetes-protective haplotype

Inflammation-Induced Citrullinated Glucose-Regulated Protein 78 Elicits Immune Responses in Human Type 1 Diabetes

Islet-specific glucose-6-phosphatase catalytic subunit-related protein-reactive CD4+ T cells in human subjects.

Lack of allergy to timothy grass pollen is not a passive phenomenon but associated with the allergen-specific modulation of immune reactivity

Lineages of human T-cell clones, including T helper 17/T helper 1 cells, isolated at different stages of anti-factor VIII immune responses.

Loss and recovery of protein productivity in genetically modified plant cell lines.

Low-affinity major histocompatibility complex-binding peptides in type 1 diabetes.

MHC II tetramers visualize human CD4+ T cell responses to Epstein-Barr virus infection and demonstrate atypical kinetics of the nuclear antigen EBNA1 response.

Memory T cells in latent Mycobacterium tuberculosis infection are directed against three antigenic islands and largely contained in a CXCR3+CCR6+ Th1 subset

Memory T cells specific to citrullinated α-enolase are enriched in the rheumatic joint

Modifying Enzymes are Elicited by ER Stress, Generating Epitopes that are Selectively Recognized by CD4+ T Cells in Patients With Type 1 Diabetes.

Modulation of CRTh2 expression on allergen-specific T cells following peptide immunotherapy

Multiplex mapping of CD4 T cell epitopes using class II tetramers

Neuroinvasive West Nile Infection Elicits Elevated and Atypically Polarized T Cell Responses That Promote a Pathogenic Outcome

Papillomavirus-specific CD4+ T cells exhibit reduced STAT-5 signaling and altered cytokine profiles in patients with recurrent respiratory papillomatosis

Peanut-specific T cell responses in patients with different clinical reactivity

Peptide-MHC cellular microarray with innovative data analysis system for simultaneously detecting multiple CD4 T-cell responses

Primary EBV Infection Induces an Acute Wave of Activated Antigen-Specific Cytotoxic CD4+ T Cells

Production and characterization of biologically active human GM-CSF secreted by genetically modified plant cells

Protecting functional β cells with a therapeutic peptide

Rapid identification and expression of human TCRs in retrogenic mice

Reassessing the role of HLA-DRB3 T-cell responses: evidence for significant expression and complementary antigen presentation.

Recognition of posttranslationally modified GAD65 epitopes in subjects with type 1 diabetes.

Searching immunodominant epitopes prior to epidemic: HLA class II-restricted SARS-CoV spike protein epitopes in unexposed individuals.

Specific immunotherapy modifies allergen-specific CD4(+) T-cell responses in an epitope-dependent manner.

Standardizing T-Cell Biomarkers in Type 1 Diabetes: Challenges and Recent Advances

Streamlined Single Cell TCR Isolation and Generation of Retroviral Vectors for In Vitro and In Vivo Expression of Human TCRs

Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis.

Differential binding of pyruvate dehydrogenase complex-E2 epitopes by DRB108:01 and DRB111:01 Is predicted by their structural motifs and correlates with disease risk

Human Leukocyte Antigen (HLA)-DRB115:01 and HLA-DRB501:01 Present Complementary Peptide Repertoires