Lista de obras - Pieter Van der Veken - Dominio Público Uruguay

1,2,3-Triazolylalkylribitol derivatives as nucleoside hydrolase inhibitors

artículo científico publicado en 2007

3-methyl-1,2,3-butanetricarboxylic acid: An atmospheric tracer for terpene secondary organic aerosol

article

ATG4B inhibitors with a benzotropolone core structure block autophagy and augment efficiency of chemotherapy in mice

artículo científico publicado en 2017

Acylated Gly-(2-cyano)pyrrolidines as inhibitors of fibroblast activation protein (FAP) and the issue of FAP/prolyl oligopeptidase (PREP)-selectivity

artículo científico publicado en 2012

Adhesion of PLGA or Eudragit/PLGA nanoparticles to Staphylococcus and Pseudomonas

artículo científico publicado en 2007

An essential signal peptide peptidase identified in an RNAi screen of serine peptidases of Trypanosoma brucei

artículo científico publicado en 2015

Asymmetric synthesis of γ-chloro-α,β-diamino- and β,γ-aziridino-α-aminoacylpyrrolidines and -piperidines via stereoselective Mannich-type additions of N-(diphenylmethylene)glycinamides across α-chloro-N-sulfinylimines ⬇️

artículo científico publicado en 2012

Author Correction: Virtual screening for inhibitors of the human TSLP:TSLPR interaction.

artículo científico publicado en 2018

Blockade of fibroblast activation protein in combination with radiation treatment in murine models of pancreatic adenocarcinoma

scientific article published on 06 February 2019

Carboxylate isosteres for caspase inhibitors: the acylsulfonamide case revisited.

artículo científico publicado en 2017

Caspase-3 probes for PET imaging of apoptotic tumor response to anticancer therapy

scientific article published on 01 May 2019

Circulating Stromal Cell-Derived Factor 1α Levels in Heart Failure: A Matter of Proper Sampling.

artículo científico publicado en 2015

Crystal structure of Porphyromonas gingivalis dipeptidyl peptidase 4 and structure-activity relationships based on inhibitor profiling

artículo científico publicado en 2017

Design and evaluation of Trypanosoma brucei metacaspase inhibitors.

artículo científico publicado en 2010

Design, synthesis, and SAR of potent and selective dipeptide-derived inhibitors for dipeptidyl peptidases.

artículo científico publicado en 2003

Development and in vitro evaluation of a vaginal microbicide gel formulation for UAMC01398, a novel diaryltriazine NNRTI against HIV-1.

artículo científico publicado en 2013

Development of a novel antibody-tetrazine conjugate for bioorthogonal pretargeting

artículo científico publicado en 2016

Development of a novel chemical probe for the selective enrichment of phosphorylated serine- and threonine-containing peptides

artículo científico publicado en 2005

Development of irreversible diphenyl phosphonate inhibitors for urokinase plasminogen activator

artículo científico publicado en 2004

Development of potent and selective dipeptidyl peptidase II inhibitors

article

Diaryltriazine non-nucleoside reverse transcriptase inhibitors are potent candidates for pre-exposure prophylaxis in the prevention of sexual HIV transmission

artículo científico publicado en 2013

Differential characterization using readily accessible NMR experiments of novel N- and O-alkylated quinolin-4-ol, 1,5-naphthyridin-4-ol and quinazolin-4-ol derivatives with antimycobacterial activity

artículo científico publicado en 2016

Dipeptidyl alpha-fluorovinyl Michael acceptors: synthesis and activity against cysteine proteases

artículo científico publicado en 2007

Dipeptidyl peptidase 8/9-like activity in human leukocytes

artículo científico publicado en 2007

Dipeptidyl peptidase II and leukocyte cell death.

artículo científico publicado en 2006

Dipeptidyl peptidases in atherosclerosis: expression and role in macrophage differentiation, activation and apoptosis.

artículo científico publicado en 2013

Diphenyl phosphonate inhibitors for the urokinase-type plasminogen activator: optimization of the P4 position.

artículo científico publicado en 2006

Discovery of Novel, Drug-Like Ferroptosis Inhibitors with in Vivo Efficacy

article

Efforts towards an On-Target Version of the Groebke-Blackburn-Bienaymé (GBB) Reaction for Discovery of Druglike Urokinase (uPA) Inhibitors

artículo científico publicado en 2019

Enzyme activity and immunohistochemical localization of dipeptidyl peptidase 8 and 9 in male reproductive tissues

artículo científico publicado en 2009

Evaluation of [18 F]BR420 and [18 F]BR351 as radiotracers for MMP-9 imaging in colorectal cancer

artículo científico publicado en 2016

Evaluation of nucleoside hydrolase inhibitors for treatment of African trypanosomiasis

artículo científico publicado en 2010

Expression and spatial heterogeneity of dipeptidyl peptidases in endothelial cells of conduct vessels and capillaries.

artículo científico publicado en 2011

Extended Structure–Activity Relationship and Pharmacokinetic Investigation of (4-Quinolinoyl)glycyl-2-cyanopyrrolidine Inhibitors of Fibroblast Activation Protein (FAP)

article

Fluoro-Olefins as Peptidomimetic Inhibitors of Dipeptidyl Peptidases

scientific article published on 01 March 2005

Formation of secondary organic aerosol marker compounds from the photooxidation of isoprene and isoprene-derived alkene diols under low-NOx conditions

scientific article published on 01 January 2013

Four day inhibition of prolyl oligopeptidase causes significant changes in the peptidome of rat brain, liver and kidney.

artículo científico publicado en 2012

From human immunodeficiency virus non-nucleoside reverse transcriptase inhibitors to potent and selective antitrypanosomal compounds.

artículo científico publicado en 2014

Gamma-amino-substituted analogues of 1-[(S)-2,4-diaminobutanoyl]piperidine as highly potent and selective dipeptidyl peptidase II inhibitors

artículo científico publicado en 2004

Glutathione-like tripeptides as inhibitors of glutathionylspermidine synthetase. Part 2: substitution of the glycine part

artículo científico publicado en 2002

Hydroxydicarboxylic Acids: Markers for Secondary Organic Aerosol from the Photooxidation of α-Pinene

article

Identification and Profiling of Hydantoins-A Novel Class of Potent Antimycobacterial DprE1 Inhibitors

scientific article published on 13 December 2018

In Vivo Amyloid-β Imaging in the APPPS1-21 Transgenic Mouse Model with a (89)Zr-Labeled Monoclonal Antibody

artículo científico publicado en 2016

In situ prolyl oligopeptidase activity assay in neural cell cultures

article

In vivo evaluation of (18)F-labeled TCO for pre-targeted PET imaging in the brain

artículo científico publicado en 2014

Increased tissue and circulating levels of dipeptidyl peptidase-IV enzymatic activity in patients with pancreatic ductal adenocarcinoma.

artículo científico publicado en 2016

Inhibitor screening and enzymatic activity determination for autophagy target Atg4B using a gel electrophoresis-based assay

artículo científico publicado en 2016

Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 1: identification of dipeptide derived leads

artículo científico publicado en 2008

Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 2: isoindoline containing inhibitors

artículo científico publicado en 2008

Irreversible Inhibition of Dipeptidyl Peptidase 8 by Dipeptide-Derived Diaryl Phosphonates

scientific article published on 24 October 2007

Kinetic investigation of human dipeptidyl peptidase II (DPPII)-mediated hydrolysis of dipeptide derivatives and its identification as quiescent cell proline dipeptidase (QPP)/dipeptidyl peptidase 7 (DPP7).

artículo científico publicado en 2005

Lead Optimization of Phthalazinone Phosphodiesterase Inhibitors as Novel Antitrypanosomal Compounds

artículo científico publicado en 2020

Ligand-induced conformational changes in prolyl oligopeptidase: a kinetic approach

artículo científico publicado en 2017

Mass spectrometric characterization of organosulfates related to secondary organic aerosol from isoprene

artículo científico publicado en 2013

Method comparison of dipeptidyl peptidase IV activity assays and their application in biological samples containing reversible inhibitors

scientific article published on 07 November 2011

Multi-slice computed tomography with N1177 identifies ruptured atherosclerotic plaques in rabbits.

artículo científico publicado en 2009

N-Arylmethyl substituted iminoribitol derivatives as inhibitors of a purine specific nucleoside hydrolase

artículo científico publicado en 2008

Newly developed serine protease inhibitors decrease visceral hypersensitivity in a post-inflammatory rat model for irritable bowel syndrome

artículo científico publicado en 2018

Novel Ferroptosis Inhibitors with Improved Potency and ADME Properties

artículo científico publicado en 2015

Novel diarylpyridinones, diarylpyridazinones and diarylphthalazinones as potential HIV-1 nonnucleoside reverse transcriptase inhibitors (NNRTIs).

artículo científico publicado en 2011

Novel drug discovery strategies for atherosclerosis that target necrosis and necroptosis.

artículo científico publicado en 2018

Novel selective glucocorticoid receptor agonists (SEGRAs) with a covalent warhead for long-lasting inhibition.

artículo científico publicado en 2016

Novel triazine dimers with potent antitrypanosomal activity.

artículo científico publicado en 2017

Occupational exposure to noise and the prevalence of hearing loss in a Belgian military population: A cross-sectional study ⬇️

artículo científico publicado el 1 de enero de 2011

Optimization of the pharmacokinetic properties of potent anti-trypanosomal triazine derivatives.

artículo científico publicado en 2018

P2-substituted N-acylprolylpyrrolidine inhibitors of prolyl oligopeptidase: biochemical evaluation, binding mode determination, and assessment in a cellular model of synucleinopathy

artículo científico publicado en 2012

Plasma carboxypeptidase U (CPU, CPB2, TAFIa) generation during in vitro clot lysis and its interplay between coagulation and fibrinolysis.

artículo científico publicado en 2017

Plasma levels of carboxypeptidase U (CPU, CPB2 or TAFIa) are elevated in patients with acute myocardial infarction

artículo científico publicado en 2015

Preclinical evaluation of [111 In]MICA-401, an activity-based probe for SPECT imaging of in vivo uPA activity

artículo científico publicado en 2016

Probing for improved selectivity with dipeptide-derived inhibitors of dipeptidyl peptidases 8 and 9: the impact of P1-variation

article

Prolyl carboxypeptidase purified from human placenta: its characterization and identification as an apelin-cleaving enzyme

artículo científico publicado en 2016

Prolyl peptidases related to dipeptidyl peptidase IV: potential of specific inhibitors in drug discovery

artículo científico publicado en 2007

Prolylisoxazoles: potent inhibitors of prolyloligopeptidase with antitrypanosomal activity

artículo científico publicado en 2003

Purification and characterization of dipeptidyl peptidase IV-like enzymes from bovine testes

scientific article published on 01 May 2008

Rapid parallel synthesis of dipeptide diphenyl phosphonate esters as inhibitors of dipeptidyl peptidases

artículo científico publicado en 2003

Repositioning the substrate activity screening (SAS) approach as a fragment-based method for identification of weak binders

artículo científico publicado en 2014

Resistance and cross-resistance profile of the diaryltriazine NNRTI and candidate microbicide UAMC01398.

artículo científico publicado en 2016

Schistosomicidal and molluscicidal activities of aminoalkylamino substituted neo- and norneocryptolepine derivatives

artículo científico publicado en 2012

Searching for New Leads for Tuberculosis: Design, Synthesis, and Biological Evaluation of Novel 2-Quinolin-4-yloxyacetamides.

artículo científico publicado en 2016

Selective Glucocorticoid Receptor Properties of GSK866 Analogs with Cysteine Reactive Warheads

artículo científico publicado en 2017

Selective Inhibitors of Fibroblast Activation Protein (FAP) with a (4-Quinolinoyl)-glycyl-2-cyanopyrrolidine Scaffold

artículo científico publicado en 2013

Selective inhibitors of fibroblast activation protein (FAP) with a xanthine scaffold

article

Small, potent, and selective diaryl phosphonate inhibitors for urokinase-type plasminogen activator with in vivo antimetastatic properties

artículo científico publicado en 2007

Sorafenib tosylate inhibits directly necrosome complex formation and protects in mouse models of inflammation and tissue injury.

artículo científico publicado en 2017

Structure-activity relationship studies on isoindoline inhibitors of dipeptidyl peptidases 8 and 9 (DPP8, DPP9): is DPP8-selectivity an attainable goal?

artículo científico publicado en 2011

Structures of purine nucleosidase from Trypanosoma brucei bound to isozyme-specific trypanocidals and a novel metalorganic inhibitor

artículo científico publicado en 2013

Substrate Activity Screening (SAS) and Related Approaches in Medicinal Chemistry

artículo científico publicado en 2016

Synthesis and Evaluation of a Zr-89-Labeled Monoclonal Antibody for Immuno-PET Imaging of Amyloid-β Deposition in the Brain

artículo científico publicado en 2016

Synthesis and antiplasmodial activity of aminoalkylamino-substituted neocryptolepine derivatives

artículo científico publicado en 2009

Synthesis and biochemical evaluation of guanidino-alkyl-ribitol derivatives as nucleoside hydrolase inhibitors

artículo científico publicado en 2007

Synthesis and dipeptidyl peptidase inhibition of N-(4-substituted-2,4-diaminobutanoyl)piperidines

artículo científico publicado en 2006

Synthesis and electrophysiological characterization of cyclic morphiceptin analogues

artículo científico publicado en 2004

Synthesis and evaluation of non-basic inhibitors of urokinase-type plasminogen activator (uPA)

artículo científico publicado en 2011

Synthesis and in vivo preclinical evaluation of an (18)F labeled uPA inhibitor as a potential PET imaging agent

artículo científico publicado en 2014

Synthesis and preclinical evaluation of an 18F labeled PDE7 inhibitor for PET neuroimaging

artículo científico publicado en 2015

Synthesis of bicyclic N-arylmethyl-substituted iminoribitol derivatives as selective nucleoside hydrolase inhibitors.

artículo científico publicado en 2009

Synthesis, evaluation and structure-activity relationships of triazine dimers as novel antiviral agents.

artículo científico publicado en 2012

Terpenylic acid and related compounds from the oxidation of alpha-pinene: implications for new particle formation and growth above forests

artículo científico publicado en 2009

The Dipeptidyl Peptidases 4, 8, and 9 in Mouse Monocytes and Macrophages: DPP8/9 Inhibition Attenuates M1 Macrophage Activation in Mice

artículo científico publicado en 2015

The Effect of Acute Pharmacological Inhibition of Urokinase Plasminogen Activator and Neuropsin Extracellular Proteases on Neuronal Networks in vitro

scholarly article published 20 February 2018

The first potent diphenyl phosphonate KLK4 inhibitors with unexpected binding kinetics

The therapeutic potential of inhibitors of dipeptidyl peptidase IV (DPP IV) and related proline-specific dipeptidyl aminopeptidases.

artículo científico publicado en 2005

Tozasertib Analogues as Inhibitors of Necroptotic Cell Death

artículo científico publicado en 2018

UPLC-TQD-MS/MS Method Validation for Quality Control of Alkaloid Content in <i>Lepidium meyenii</i> (Maca)-Containing Food and Dietary Supplements

artículo científico publicado en 2024

Validation of a specific prolylcarboxypeptidase activity assay and its suitability for plasma and serum measurements

artículo científico publicado en 2013

Virtual screening for inhibitors of the human TSLP:TSLPR interaction.

artículo científico publicado en 2017

Withaferin A inhibits NF-kappaB activation by targeting cysteine 179 in IKKβ.

artículo científico publicado en 2014

α-Amino Diphenyl Phosphonates as Novel Inhibitors of Escherichia coli ClpP Protease

scientific article published on 11 January 2019

α-ketoheterocycles as inhibitors of Leishmania mexicana cysteine protease CPB.

artículo científico publicado en 2010

Lista de obras de Pieter Van der Veken

1,2,3-Triazolylalkylribitol derivatives as nucleoside hydrolase inhibitors

3-methyl-1,2,3-butanetricarboxylic acid: An atmospheric tracer for terpene secondary organic aerosol

ATG4B inhibitors with a benzotropolone core structure block autophagy and augment efficiency of chemotherapy in mice

Acylated Gly-(2-cyano)pyrrolidines as inhibitors of fibroblast activation protein (FAP) and the issue of FAP/prolyl oligopeptidase (PREP)-selectivity

Adhesion of PLGA or Eudragit/PLGA nanoparticles to Staphylococcus and Pseudomonas

An essential signal peptide peptidase identified in an RNAi screen of serine peptidases of Trypanosoma brucei

Asymmetric synthesis of γ-chloro-α,β-diamino- and β,γ-aziridino-α-aminoacylpyrrolidines and -piperidines via stereoselective Mannich-type additions of N-(diphenylmethylene)glycinamides across α-chloro-N-sulfinylimines ⬇️

Author Correction: Virtual screening for inhibitors of the human TSLP:TSLPR interaction.

Blockade of fibroblast activation protein in combination with radiation treatment in murine models of pancreatic adenocarcinoma

Carboxylate isosteres for caspase inhibitors: the acylsulfonamide case revisited.

Caspase-3 probes for PET imaging of apoptotic tumor response to anticancer therapy

Circulating Stromal Cell-Derived Factor 1α Levels in Heart Failure: A Matter of Proper Sampling.

Crystal structure of Porphyromonas gingivalis dipeptidyl peptidase 4 and structure-activity relationships based on inhibitor profiling

Design and evaluation of Trypanosoma brucei metacaspase inhibitors.

Design, synthesis, and SAR of potent and selective dipeptide-derived inhibitors for dipeptidyl peptidases.

Development and in vitro evaluation of a vaginal microbicide gel formulation for UAMC01398, a novel diaryltriazine NNRTI against HIV-1.

Development of a novel antibody-tetrazine conjugate for bioorthogonal pretargeting

Development of a novel chemical probe for the selective enrichment of phosphorylated serine- and threonine-containing peptides

Development of irreversible diphenyl phosphonate inhibitors for urokinase plasminogen activator

Development of potent and selective dipeptidyl peptidase II inhibitors

Diaryltriazine non-nucleoside reverse transcriptase inhibitors are potent candidates for pre-exposure prophylaxis in the prevention of sexual HIV transmission

Differential characterization using readily accessible NMR experiments of novel N- and O-alkylated quinolin-4-ol, 1,5-naphthyridin-4-ol and quinazolin-4-ol derivatives with antimycobacterial activity

Dipeptidyl alpha-fluorovinyl Michael acceptors: synthesis and activity against cysteine proteases

Dipeptidyl peptidase 8/9-like activity in human leukocytes

Dipeptidyl peptidase II and leukocyte cell death.

Dipeptidyl peptidases in atherosclerosis: expression and role in macrophage differentiation, activation and apoptosis.

Diphenyl phosphonate inhibitors for the urokinase-type plasminogen activator: optimization of the P4 position.

Discovery of Novel, Drug-Like Ferroptosis Inhibitors with in Vivo Efficacy

Efforts towards an On-Target Version of the Groebke-Blackburn-Bienaymé (GBB) Reaction for Discovery of Druglike Urokinase (uPA) Inhibitors

Enzyme activity and immunohistochemical localization of dipeptidyl peptidase 8 and 9 in male reproductive tissues

Evaluation of [18 F]BR420 and [18 F]BR351 as radiotracers for MMP-9 imaging in colorectal cancer

Evaluation of nucleoside hydrolase inhibitors for treatment of African trypanosomiasis

Expression and spatial heterogeneity of dipeptidyl peptidases in endothelial cells of conduct vessels and capillaries.

Extended Structure–Activity Relationship and Pharmacokinetic Investigation of (4-Quinolinoyl)glycyl-2-cyanopyrrolidine Inhibitors of Fibroblast Activation Protein (FAP)

Fluoro-Olefins as Peptidomimetic Inhibitors of Dipeptidyl Peptidases

Formation of secondary organic aerosol marker compounds from the photooxidation of isoprene and isoprene-derived alkene diols under low-NOx conditions

Four day inhibition of prolyl oligopeptidase causes significant changes in the peptidome of rat brain, liver and kidney.

From human immunodeficiency virus non-nucleoside reverse transcriptase inhibitors to potent and selective antitrypanosomal compounds.

Gamma-amino-substituted analogues of 1-[(S)-2,4-diaminobutanoyl]piperidine as highly potent and selective dipeptidyl peptidase II inhibitors

Glutathione-like tripeptides as inhibitors of glutathionylspermidine synthetase. Part 2: substitution of the glycine part

Hydroxydicarboxylic Acids: Markers for Secondary Organic Aerosol from the Photooxidation of α-Pinene

Identification and Profiling of Hydantoins-A Novel Class of Potent Antimycobacterial DprE1 Inhibitors

In Vivo Amyloid-β Imaging in the APPPS1-21 Transgenic Mouse Model with a (89)Zr-Labeled Monoclonal Antibody

In situ prolyl oligopeptidase activity assay in neural cell cultures

In vivo evaluation of (18)F-labeled TCO for pre-targeted PET imaging in the brain

Increased tissue and circulating levels of dipeptidyl peptidase-IV enzymatic activity in patients with pancreatic ductal adenocarcinoma.

Inhibitor screening and enzymatic activity determination for autophagy target Atg4B using a gel electrophoresis-based assay

Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 1: identification of dipeptide derived leads

Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 2: isoindoline containing inhibitors

Irreversible Inhibition of Dipeptidyl Peptidase 8 by Dipeptide-Derived Diaryl Phosphonates

Kinetic investigation of human dipeptidyl peptidase II (DPPII)-mediated hydrolysis of dipeptide derivatives and its identification as quiescent cell proline dipeptidase (QPP)/dipeptidyl peptidase 7 (DPP7).

Lead Optimization of Phthalazinone Phosphodiesterase Inhibitors as Novel Antitrypanosomal Compounds

Ligand-induced conformational changes in prolyl oligopeptidase: a kinetic approach

Mass spectrometric characterization of organosulfates related to secondary organic aerosol from isoprene

Method comparison of dipeptidyl peptidase IV activity assays and their application in biological samples containing reversible inhibitors

Multi-slice computed tomography with N1177 identifies ruptured atherosclerotic plaques in rabbits.

N-Arylmethyl substituted iminoribitol derivatives as inhibitors of a purine specific nucleoside hydrolase

Newly developed serine protease inhibitors decrease visceral hypersensitivity in a post-inflammatory rat model for irritable bowel syndrome

Novel Ferroptosis Inhibitors with Improved Potency and ADME Properties

Novel diarylpyridinones, diarylpyridazinones and diarylphthalazinones as potential HIV-1 nonnucleoside reverse transcriptase inhibitors (NNRTIs).

Novel drug discovery strategies for atherosclerosis that target necrosis and necroptosis.

Novel selective glucocorticoid receptor agonists (SEGRAs) with a covalent warhead for long-lasting inhibition.

Novel triazine dimers with potent antitrypanosomal activity.

Occupational exposure to noise and the prevalence of hearing loss in a Belgian military population: A cross-sectional study ⬇️

Optimization of the pharmacokinetic properties of potent anti-trypanosomal triazine derivatives.

P2-substituted N-acylprolylpyrrolidine inhibitors of prolyl oligopeptidase: biochemical evaluation, binding mode determination, and assessment in a cellular model of synucleinopathy

Plasma carboxypeptidase U (CPU, CPB2, TAFIa) generation during in vitro clot lysis and its interplay between coagulation and fibrinolysis.

Plasma levels of carboxypeptidase U (CPU, CPB2 or TAFIa) are elevated in patients with acute myocardial infarction

Preclinical evaluation of [111 In]MICA-401, an activity-based probe for SPECT imaging of in vivo uPA activity

Probing for improved selectivity with dipeptide-derived inhibitors of dipeptidyl peptidases 8 and 9: the impact of P1-variation

Prolyl carboxypeptidase purified from human placenta: its characterization and identification as an apelin-cleaving enzyme

Prolyl peptidases related to dipeptidyl peptidase IV: potential of specific inhibitors in drug discovery

Prolylisoxazoles: potent inhibitors of prolyloligopeptidase with antitrypanosomal activity

Purification and characterization of dipeptidyl peptidase IV-like enzymes from bovine testes

Rapid parallel synthesis of dipeptide diphenyl phosphonate esters as inhibitors of dipeptidyl peptidases

Repositioning the substrate activity screening (SAS) approach as a fragment-based method for identification of weak binders

Resistance and cross-resistance profile of the diaryltriazine NNRTI and candidate microbicide UAMC01398.

Schistosomicidal and molluscicidal activities of aminoalkylamino substituted neo- and norneocryptolepine derivatives

Searching for New Leads for Tuberculosis: Design, Synthesis, and Biological Evaluation of Novel 2-Quinolin-4-yloxyacetamides.