Lista de obras - Alexander K Buell - Dominio Público Uruguay

A label-free, quantitative assay of amyloid fibril growth based on intrinsic fluorescence

artículo científico publicado en 2013

A microfluidic diffusion platform for characterizing the size of lipid vesicles and the thermodynamics of protein-lipid interactions.

artículo científico publicado en 2018

Acceleration of α-synuclein aggregation

artículo científico publicado en 2017

Amyloid formation and depolymerization of tumor suppressor p16INK4a are regulated by a thiol-dependent redox mechanism ⬇️

artículo científico publicado en 2024

An engineered monomer binding-protein for α-synuclein efficiently inhibits the proliferation of amyloid fibrils

scientific article published on 21 August 2019

Atomic structure of PI3-kinase SH3 amyloid fibrils by cryo-electron microscopy

scientific article published on 21 August 2019

Binding of the molecular chaperone αB-crystallin to Aβ amyloid fibrils inhibits fibril elongation

artículo científico publicado en 2011

Biosensor-based label-free assays of amyloid growth

artículo científico publicado en 2009

C-terminal truncation of α-synuclein promotes amyloid fibril amplification at physiological pH

artículo científico publicado en 2018

Capillary flow experiments for thermodynamic and kinetic characterization of protein liquid-liquid phase separation

artículo científico

Chemical properties of lipids strongly affect the kinetics of the membrane-induced aggregation of α-synuclein

artículo científico publicado en 2016

Compact fibril-like structure of amyloid β-peptide (1-42) monomers

artículo científico publicado en 2021

Correction to: Reproducibility and accuracy of microscale thermophoresis in the NanoTemper Monolith: a multi laboratory benchmark study

scientific article published in 2021

Detailed Analysis of the Energy Barriers for Amyloid Fibril Growth

article

Detection and Characterization of Small Molecule Interactions with Fibrillar Protein Aggregates Using Microscale Thermophoresis

artículo científico publicado en 2017

Direct observation of heterogeneous amyloid fibril growth kinetics via two-color super-resolution microscopy

artículo científico publicado en 2013

Distinct thermodynamic signatures of oligomer generation in the aggregation of the amyloid-β peptide.

artículo científico publicado en 2018

Electrostatic effects in filamentous protein aggregation

artículo científico publicado en 2013

Expanding the solvent chemical space for self-assembly of dipeptide nanostructures.

artículo científico publicado en 2014

Frequency Factors in a Landscape Model of Filamentous Protein Aggregation

artículo científico publicado en 2010

Influence of specific HSP70 domains on fibril formation of the yeast prion protein Ure2

artículo científico publicado en 2013

Influence of the protein context on the polyglutamine length-dependent elongation of amyloid fibrils

artículo científico publicado en 2014

Interactions between amyloidophilic dyes and their relevance to studies of amyloid inhibitors

artículo científico publicado en 2010

Kinetic barriers to α-synuclein protofilament formation and conversion into mature fibrils

artículo científico publicado en 2018

Lipid Dynamics and Phase Transition within α-Synuclein Amyloid Fibrils

scientific article published on 06 December 2019

Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation

artículo científico publicado en 2015

Measuring the kinetics of amyloid fibril elongation using quartz crystal microbalances

scientific article published on 01 January 2012

Mutations associated with familial Parkinson's disease alter the initiation and amplification steps of α-synuclein aggregation

artículo científico publicado en 2016

Mécanismes fondamentaux de formation de fibres amyloïdes par la protéine α-synucléine dans la maladie de Parkinson

artículo científico publicado en 2015

Nanobodies Raised against Monomeric α-Synuclein Distinguish between Fibrils at Different Maturation Stages

scientific article published on 01 April 2013

Nanobodies raised against monomeric ɑ-synuclein inhibit fibril formation and destabilize toxic oligomeric species

artículo científico publicado en 2017

Nanoscopic insights into seeding mechanisms and toxicity of α-synuclein species in neurons

artículo científico publicado en 2016

Nanostructured films from hierarchical self-assembly of amyloidogenic proteins

artículo científico publicado en 2010

Opposed Effects of Dityrosine Formation in Soluble and Aggregated α-Synuclein on Fibril Growth

artículo científico publicado en 2017

Ostwald's rule of stages governs structural transitions and morphology of dipeptide supramolecular polymers

artículo científico publicado en 2014

Photodissociation dynamics of the reaction H2CO-->H+HCO via the singlet (S0) and triplet (T1) surfaces

artículo científico publicado en 2007

Population of nonnative states of lysozyme variants drives amyloid fibril formation

artículo científico publicado en 2011

Position-dependent electrostatic protection against protein aggregation

artículo científico publicado en 2009

Probing small molecule binding to amyloid fibrils

artículo científico publicado en 2011

Protein Aggregate-Ligand Binding Assays Based on Microfluidic Diffusional Separation

artículo científico publicado en 2016

Protein Aggregation in Crowded Environments

artículo científico publicado en 2010

Protein microgels from amyloid fibril networks

artículo científico publicado en 2015

Pyroglutamate-modified Aβ(3-42) affects aggregation kinetics of Aβ(1-42) by accelerating primary and secondary pathways

artículo científico publicado en 2017

Quantitative Analysis of Diffusive Reactions at the Solid-Liquid Interface in Finite Systems.

artículo científico publicado en 2014

Quantitative thermophoretic study of disease-related protein aggregates

artículo científico publicado en 2016

Relationship between prion propensity and the rates of individual molecular steps of fibril assembly

artículo científico publicado en 2011

Role of Hydrophobicity and Charge of Amyloid-Beta Oligomer Eliminating d-Peptides in the Interaction with Amyloid-Beta Monomers

artículo científico publicado en 2018

Scaling behaviour and rate-determining steps in filamentous self-assembly

artículo científico publicado en 2017

Solution conditions determine the relative importance of nucleation and growth processes in α-synuclein aggregation

artículo científico publicado en 2014

Spatial Propagation of Protein Polymerization

scientific article published in Physical Review Letters

Structural insights from lipid-bilayer nanodiscs link α-Synuclein membrane-binding modes to amyloid fibril formation

artículo científico publicado en 2018

Surface attachment of protein fibrils via covalent modification strategies

artículo científico publicado en 2010

Synthesis of Nonequilibrium Supramolecular Peptide Polymers on a Microfluidic Platform

artículo científico publicado en 2016

Targeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson's disease

artículo científico publicado en 2014

The Aggregation Conditions Define Whether EGCG is an Inhibitor or Enhancer of α-Synuclein Amyloid Fibril Formation

scientific article published on 14 March 2020

The Environment Is a Key Factor in Determining the Anti-Amyloid Efficacy of EGCG

scientific article published on 11 December 2019

The Kinetics, Thermodynamics and Mechanisms of Short Aromatic Peptide Self-Assembly

scientific article published on 01 January 2019

The Nucleation of Protein Aggregates - From Crystals to Amyloid Fibrils

artículo científico publicado en 2016

The Properties of α-Synuclein Secondary Nuclei Are Dominated by the Solution Conditions Rather than the Seed Fibril Strain

scientific article published on 28 February 2020

The growth of amyloid fibrils: rates and mechanisms

artículo científico publicado en 2019

The hydrophobic effect characterises the thermodynamic signature of amyloid fibril growth

scientific article published on 04 May 2020

The length distribution of frangible biofilaments.

artículo científico publicado en 2015

The physical chemistry of the amyloid phenomenon: thermodynamics and kinetics of filamentous protein aggregation

artículo científico publicado en 2014

The role of stable α-synuclein oligomers in the molecular events underlying amyloid formation.

artículo científico publicado en 2014

Thermodynamics of Polypeptide Supramolecular Assembly in the Short-Chain Limit

artículo científico publicado en 2017

Thermodynamics of amyloid fibril formation from chemical depolymerization

artículo científico publicado en 2019

Three-dimensional domain swapping and supramolecular protein assembly: insights from the X-ray structure of a dimeric swapped variant of human pancreatic RNase

artículo científico publicado en 2013

α-Synuclein-derived lipoparticles in the study of α-Synuclein amyloid fibril formation

artículo científico publicado en 2019

β-Synuclein suppresses both the initiation and amplification steps of α-synuclein aggregation via competitive binding to surfaces.

artículo científico publicado en 2016

Lista de obras de Alexander K Buell

A label-free, quantitative assay of amyloid fibril growth based on intrinsic fluorescence

A microfluidic diffusion platform for characterizing the size of lipid vesicles and the thermodynamics of protein-lipid interactions.

Acceleration of α-synuclein aggregation

Amyloid formation and depolymerization of tumor suppressor p16INK4a are regulated by a thiol-dependent redox mechanism ⬇️

An engineered monomer binding-protein for α-synuclein efficiently inhibits the proliferation of amyloid fibrils

Atomic structure of PI3-kinase SH3 amyloid fibrils by cryo-electron microscopy

Binding of the molecular chaperone αB-crystallin to Aβ amyloid fibrils inhibits fibril elongation

Biosensor-based label-free assays of amyloid growth

C-terminal truncation of α-synuclein promotes amyloid fibril amplification at physiological pH

Capillary flow experiments for thermodynamic and kinetic characterization of protein liquid-liquid phase separation

Chemical properties of lipids strongly affect the kinetics of the membrane-induced aggregation of α-synuclein

Compact fibril-like structure of amyloid β-peptide (1-42) monomers

Correction to: Reproducibility and accuracy of microscale thermophoresis in the NanoTemper Monolith: a multi laboratory benchmark study

Detailed Analysis of the Energy Barriers for Amyloid Fibril Growth

Detection and Characterization of Small Molecule Interactions with Fibrillar Protein Aggregates Using Microscale Thermophoresis

Direct observation of heterogeneous amyloid fibril growth kinetics via two-color super-resolution microscopy

Distinct thermodynamic signatures of oligomer generation in the aggregation of the amyloid-β peptide.

Electrostatic effects in filamentous protein aggregation

Expanding the solvent chemical space for self-assembly of dipeptide nanostructures.

Frequency Factors in a Landscape Model of Filamentous Protein Aggregation

Influence of specific HSP70 domains on fibril formation of the yeast prion protein Ure2

Influence of the protein context on the polyglutamine length-dependent elongation of amyloid fibrils

Interactions between amyloidophilic dyes and their relevance to studies of amyloid inhibitors

Kinetic barriers to α-synuclein protofilament formation and conversion into mature fibrils

Lipid Dynamics and Phase Transition within α-Synuclein Amyloid Fibrils

Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation

Measuring the kinetics of amyloid fibril elongation using quartz crystal microbalances

Mutations associated with familial Parkinson's disease alter the initiation and amplification steps of α-synuclein aggregation

Mécanismes fondamentaux de formation de fibres amyloïdes par la protéine α-synucléine dans la maladie de Parkinson

Nanobodies Raised against Monomeric α-Synuclein Distinguish between Fibrils at Different Maturation Stages

Nanobodies raised against monomeric ɑ-synuclein inhibit fibril formation and destabilize toxic oligomeric species

Nanoscopic insights into seeding mechanisms and toxicity of α-synuclein species in neurons

Nanostructured films from hierarchical self-assembly of amyloidogenic proteins

Opposed Effects of Dityrosine Formation in Soluble and Aggregated α-Synuclein on Fibril Growth

Ostwald's rule of stages governs structural transitions and morphology of dipeptide supramolecular polymers

Photodissociation dynamics of the reaction H2CO-->H+HCO via the singlet (S0) and triplet (T1) surfaces

Population of nonnative states of lysozyme variants drives amyloid fibril formation

Position-dependent electrostatic protection against protein aggregation

Probing small molecule binding to amyloid fibrils

Protein Aggregate-Ligand Binding Assays Based on Microfluidic Diffusional Separation

Protein Aggregation in Crowded Environments

Protein microgels from amyloid fibril networks

Pyroglutamate-modified Aβ(3-42) affects aggregation kinetics of Aβ(1-42) by accelerating primary and secondary pathways

Quantitative Analysis of Diffusive Reactions at the Solid-Liquid Interface in Finite Systems.

Quantitative thermophoretic study of disease-related protein aggregates

Relationship between prion propensity and the rates of individual molecular steps of fibril assembly

Role of Hydrophobicity and Charge of Amyloid-Beta Oligomer Eliminating d-Peptides in the Interaction with Amyloid-Beta Monomers

Scaling behaviour and rate-determining steps in filamentous self-assembly

Solution conditions determine the relative importance of nucleation and growth processes in α-synuclein aggregation

Spatial Propagation of Protein Polymerization

Structural insights from lipid-bilayer nanodiscs link α-Synuclein membrane-binding modes to amyloid fibril formation

Surface attachment of protein fibrils via covalent modification strategies

Synthesis of Nonequilibrium Supramolecular Peptide Polymers on a Microfluidic Platform

Targeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson's disease

The Aggregation Conditions Define Whether EGCG is an Inhibitor or Enhancer of α-Synuclein Amyloid Fibril Formation

The Environment Is a Key Factor in Determining the Anti-Amyloid Efficacy of EGCG

The Kinetics, Thermodynamics and Mechanisms of Short Aromatic Peptide Self-Assembly

The Nucleation of Protein Aggregates - From Crystals to Amyloid Fibrils

The Properties of α-Synuclein Secondary Nuclei Are Dominated by the Solution Conditions Rather than the Seed Fibril Strain

The growth of amyloid fibrils: rates and mechanisms

The hydrophobic effect characterises the thermodynamic signature of amyloid fibril growth

The length distribution of frangible biofilaments.

The physical chemistry of the amyloid phenomenon: thermodynamics and kinetics of filamentous protein aggregation

The role of stable α-synuclein oligomers in the molecular events underlying amyloid formation.

Thermodynamics of Polypeptide Supramolecular Assembly in the Short-Chain Limit

Thermodynamics of amyloid fibril formation from chemical depolymerization

Three-dimensional domain swapping and supramolecular protein assembly: insights from the X-ray structure of a dimeric swapped variant of human pancreatic RNase

α-Synuclein-derived lipoparticles in the study of α-Synuclein amyloid fibril formation

β-Synuclein suppresses both the initiation and amplification steps of α-synuclein aggregation via competitive binding to surfaces.