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Lista de obras de Craig E Hughes

A global proteomics approach identifies novel phosphorylated signaling proteins in GPVI-activated platelets: involvement of G6f, a novel platelet Grb2-binding membrane adapter.

artículo científico publicado en 2006

A role for adhesion and degranulation-promoting adapter protein in collagen-induced platelet activation mediated via integrin α(2) β(1)

artículo científico publicado en 2012

Activation of glycoprotein VI (GPVI) and C-type lectin-like receptor-2 (CLEC-2) underlies platelet activation by diesel exhaust particles and other charged/hydrophobic ligands

artículo científico publicado en 2015

CLEC-2 activates Syk through dimerization

artículo científico publicado en 2010

CLEC-2 and Syk in the megakaryocytic/platelet lineage are essential for development.

artículo científico publicado en 2011

CLEC-2 is not required for platelet aggregation at arteriolar shear

artículo científico publicado en 2010

Critical Role for an acidic amino acid region in platelet signaling by the HemITAM (hemi-immunoreceptor tyrosine-based activation motif) containing receptor CLEC-2 (C-type lectin receptor-2).

artículo científico publicado en 2012

Different soluble aggregates of Aβ42 can give rise to cellular toxicity through different mechanisms

article

Differential roles for the adapters Gads and LAT in platelet activation by GPVI and CLEC-2.

artículo científico publicado en 2008

Differential roles of the PKC novel isoforms, PKCdelta and PKCepsilon, in mouse and human platelets

artículo científico publicado en 2008

Fibrin activates GPVI in human and mouse platelets

artículo científico publicado en 2015

Fucoidan is a novel platelet agonist for the C-type lectin-like receptor 2 (CLEC-2)

artículo científico publicado en 2013

G6f-like is an ITAM-containing collagen receptor in thrombocytes

artículo científico publicado en 2012

GPVI potentiation of platelet activation by thrombin and adhesion molecules independent of Src kinases and Syk.

artículo científico publicado en 2006

Globular adiponectin induces platelet activation through the collagen receptor GPVI-Fc receptor gamma chain complex

artículo científico publicado en 2008

Growth factor receptor-bound protein 2 contributes to (hem)immunoreceptor tyrosine-based activation motif-mediated signaling in platelets

artículo científico publicado en 2013

How to perform aggregometry and lumi-aggregometry in mouse platelets

artículo científico publicado en 2018

Immobilized fibrinogen activates human platelets through glycoprotein VI.

artículo científico publicado en 2018

Involvement of Src kinases and PLCgamma2 in clot retraction

artículo científico publicado en 2006

Minimal regulation of platelet activity by PECAM-1.

artículo científico publicado en 2007

Molecular basis of platelet activation by an alphaIIbbeta3-CHAMPS peptide

artículo científico publicado en 2008

Mouse podoplanin supports adhesion and aggregation of platelets under arterial shear: A novel mechanism of haemostasis.

artículo científico publicado en 2017

SLAP/SLAP2 prevent excessive platelet (hem)ITAM signaling in thrombosis and ischemic stroke in mice

artículo científico publicado en 2014

Severe platelet dysfunction in NHL patients receiving ibrutinib is absent in patients receiving acalabrutinib

Soluble aggregates present in cerebrospinal fluid change in size and mechanism of toxicity during Alzheimer's disease progression

artículo científico publicado en 2019

Syk and Src family kinases regulate C-type lectin receptor 2 (CLEC-2)-mediated clustering of podoplanin and platelet adhesion to lymphatic endothelial cells

artículo científico publicado en 2014

The N-terminal SH2 domain of Syk is required for (hem)ITAM, but not integrin, signaling in mouse platelets

artículo científico publicado en 2014

The novel Syk inhibitor R406 reveals mechanistic differences in the initiation of GPVI and CLEC-2 signaling in platelets.

artículo científico publicado en 2009

Tityus discrepans scorpion venom activates platelets through GPVI and a novel Src-dependent signaling pathway.

artículo científico publicado en 2011