Lista de obras - Philip R Taylor - Dominio Público Uruguay

A quantifiable proliferative burst of tissue macrophages restores homeostatic macrophage populations after acute inflammation

artículo científico publicado en 2011

A targeted disruption of the murine complement factor B gene resulting in loss of expression of three genes in close proximity, factor B, C2, and D17H6S45.

artículo científico publicado en 1998

Actin and phosphoinositide recruitment to fully formed Candida albicans phagosomes in mouse macrophages

artículo científico publicado en 2008

Activation of naïve CD4+ T cells re-tunes STAT1 signaling to deliver unique cytokine responses in memory CD4+ T cells

artículo científico publicado en 2019

Altered major histocompatibility complex class II peptide loading in H2-O-deficient mice

scientific journal article

Analysis of mannose receptor regulation by IL-4, IL-10, and proteolytic processing using novel monoclonal antibodies

artículo científico publicado en 2003

Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1.

artículo científico publicado en 2012

Anticancer chemotherapy-induced intratumoral recruitment and differentiation of antigen-presenting cells

artículo científico publicado en 2013

Antigen targeting reveals splenic CD169+ macrophages as promoters of germinal center B-cell responses

artículo científico publicado en 2015

CD200 receptor restriction of myeloid cell responses antagonizes antiviral immunity and facilitates cytomegalovirus persistence within mucosal tissue

artículo científico publicado en 2015

CLEC-2 is a phagocytic activation receptor expressed on murine peripheral blood neutrophils.

artículo científico publicado en 2009

Characterisation of murine MICL (CLEC12A) and evidence for an endogenous ligand

artículo científico publicado en 2008

Class IA phosphoinositide 3-kinase β and δ regulate neutrophil oxidase activation in response to Aspergillus fumigatus hyphae

artículo científico publicado en 2011

Cloning of the mouse homolog of the 126-kDa human C1q/MBL/SP-A receptor, C1qR(p)

artículo científico publicado en 1999

Complement C3 plays an essential role in the control of opportunistic fungal infections

scientific article published on 06 July 2009

Complement contributes to protective immunity against reinfection by Plasmodium chabaudi chabaudi parasites.

artículo científico publicado en 2001

Cytosolic phospholipase a2 activation by Candida albicans in alveolar macrophages: role of dectin-1.

artículo científico publicado en 2009

Dectin-1 is required for beta-glucan recognition and control of fungal infection

artículo científico publicado en 2006

Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection

artículo científico publicado en 2009

Dectin-2 is predominantly myeloid restricted and exhibits unique activation-dependent expression on maturing inflammatory monocytes elicited in vivo

artículo científico publicado en 2005

Dependence on Dectin-1 Varies With Multiple Candida Species

scientific article published on 06 August 2019

Development and characterization of novel anti-C5 monoclonal antibodies capable of inhibiting complement in multiple species

artículo científico publicado en 2019

Development of a specific system for targeting protein to metallophilic macrophages

artículo científico publicado en 2004

Development of myeloproliferative disease in 12/15-lipoxygenase deficiency

artículo científico publicado en 2012

Differential dependencies of monocytes and neutrophils on dectin-1, dectin-2 and complement for the recognition of fungal particles in inflammation

artículo científico publicado en 2012

Distinct bone marrow-derived and tissue-resident macrophage lineages proliferate at key stages during inflammation

artículo científico publicado en 2013

Effective In Vivo Gene Modification in Mouse Tissue-Resident Peritoneal Macrophages by Intraperitoneal Delivery of Lentiviral Vectors

scientific article published on 18 October 2019

Endogenous oncogenic Nras mutation promotes aberrant GM-CSF signaling in granulocytic/monocytic precursors in a murine model of chronic myelomonocytic leukemia

artículo científico publicado en 2010

Esterified eicosanoids are acutely generated by 5-lipoxygenase in primary human neutrophils and in human and murine infection

artículo científico publicado en 2011

Expression of the beta-glucan receptor, Dectin-1, on murine leukocytes in situ correlates with its function in pathogen recognition and reveals potential roles in leukocyte interactions

artículo científico publicado en 2004

Fungal recognition enhances mannose receptor shedding through dectin-1 engagement

artículo científico publicado en 2011

Hoxb8 conditionally immortalised macrophage lines model inflammatory monocytic cells with important similarity to dendritic cells

artículo científico publicado en 2011

IL-10 differentially controls the infiltration of inflammatory macrophages and antigen-presenting cells during inflammation

artículo científico publicado en 2016

In vivo functional analysis and genetic modification of in vitro-derived mouse neutrophils

artículo científico publicado en 2011

Innate immune response to human bone marrow fibroblastic cell implantation in CB17 scid/beige mice

artículo científico publicado en 2006

Integrin CD11b positively regulates TLR4-induced signalling pathways in dendritic cells but not in macrophages

artículo científico publicado en 2014

Interleukin-10 regulates the inflammasome-driven augmentation of inflammatory arthritis and joint destruction

artículo científico publicado en 2014

Interleukin-6 limits influenza-induced inflammation and protects against fatal lung pathology

artículo científico publicado en 2013

Interleukin-6 signaling drives fibrosis in unresolved inflammation

scientific article published on 09 January 2014

LAB/NTAL facilitates fungal/PAMP-induced IL-12 and IFN-γ production by repressing β-catenin activation in dendritic cells

artículo científico publicado en 2013

Macrophage Reprogramming for Therapy

artículo científico publicado en 2020

Monocyte and macrophage heterogeneity

artículo científico publicado en 2005

Monocyte heterogeneity and innate immunity

artículo científico publicado en 2003

Murine D17H6S45 (Rd) gene: polymorphism and overlap with complement factor B.

artículo científico publicado en 1997

NR4A orphan nuclear receptor family members, NR4A2 and NR4A3, regulate neutrophil number and survival

artículo científico publicado en 2017

Networks of enzymatically oxidized membrane lipids support calcium-dependent coagulation factor binding to maintain hemostasis.

artículo científico publicado en 2017

Neutrophils recruited by IL-22 in peripheral tissues function as TRAIL-dependent antiviral effectors against MCMV.

artículo científico publicado en 2014

Oxylipin metabolism is controlled by mitochondrial β-oxidation during bacterial inflammation

artículo científico publicado en 2022

PIP2 depletion and altered endocytosis caused by expression of Alzheimer's disease-protective variant PLCγ2 R522

artículo científico publicado en 2021

Paracetamol reduces influenza-induced immunopathology in a mouse model of infection without compromising virus clearance or the generation of protective immunity

artículo científico publicado en 2011

Pathways regulating cytosolic phospholipase A2 activation and eicosanoid production in macrophages by Candida albicans

artículo científico publicado en 2010

Pattern recognition receptors and differentiation antigens define murine myeloid cell heterogeneity ex vivo

artículo científico publicado en 2003

Peritoneal tissue-resident macrophages are metabolically poised to engage microbes using tissue-niche fuels

artículo científico publicado en 2017

Phagocytosis is the main CR3-mediated function affected by the lupus-associated variant of CD11b in human myeloid cells

artículo científico publicado en 2013

Phosphatidylethanolamine-esterified eicosanoids in the mouse: tissue localization and inflammation-dependent formation in Th-2 disease

artículo científico publicado en 2009

RNA interference mutant induction in vivo demonstrates the essential nature of trypanosome flagellar function during mammalian infection

artículo científico publicado en 2007

Recognition of bacterial capsular polysaccharides and lipopolysaccharides by the macrophage mannose receptor

artículo científico publicado en 2002

Regulation of cytosolic phospholipase A2 activation and cyclooxygenase 2 expression in macrophages by the beta-glucan receptor

artículo científico publicado en 2006

Restoration of pattern recognition receptor costimulation to treat chromoblastomycosis, a chronic fungal infection of the skin

artículo científico publicado en 2011

Soluble Dectin-1 as a tool to detect beta-glucans

artículo científico publicado en 2006

Stage-specific sampling by pattern recognition receptors during Candida albicans phagocytosis

artículo científico publicado en 2008

Structural and Functional Analyses of the Shedding Protease ADAM17 in HoxB8-Immortalized Macrophages and Dendritic-like Cells

article

Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors.

artículo científico publicado en 2008

Systemic lupus erythematosus, complement deficiency, and apoptosis

artículo científico publicado en 2000

The C-type lectin SIGNR1 binds Schistosoma mansoni antigens in vitro, but SIGNR1-deficient mice have normal responses during schistosome infection

artículo científico publicado en 2008

The carbohydrate-recognition domain of Dectin-2 is a C-type lectin with specificity for high mannose

artículo científico publicado en 2006

The contribution of naturally occurring IgM antibodies, IgM cross-reactivity and complement dependency in murine humoral responses to pneumococcal capsular polysaccharides

article

The mannose receptor: linking homeostasis and immunity through sugar recognition

artículo científico publicado en 2005

The myeloid 7/4-antigen defines recently generated inflammatory macrophages and is synonymous with Ly-6B.

artículo científico publicado en 2010

The protective effect of inflammatory monocytes during systemic C. albicans infection is dependent on collaboration between C-type lectin-like receptors

artículo científico publicado en 2019

The transcription factor Gata6 links tissue macrophage phenotype and proliferative renewal

artículo científico publicado en 2014

Tissue-resident macrophages

artículo científico publicado en 2013

Tissue-resident macrophages actively suppress IL-1beta release via a reactive prostanoid/IL-10 pathway

artículo científico publicado en 2020

Tissue-resident macrophages: then and now.

artículo científico publicado en 2015

Understanding local macrophage phenotypes in disease: shape-shifting macrophages

artículo científico publicado en 2015

miR-192 induces G2/M growth arrest in aristolochic acid nephropathy

artículo científico publicado en 2014

miR-21 Promotes Fibrogenesis in Peritoneal Dialysis

artículo científico publicado en 2017

Lista de obras de Philip R Taylor

A quantifiable proliferative burst of tissue macrophages restores homeostatic macrophage populations after acute inflammation

A targeted disruption of the murine complement factor B gene resulting in loss of expression of three genes in close proximity, factor B, C2, and D17H6S45.

Actin and phosphoinositide recruitment to fully formed Candida albicans phagosomes in mouse macrophages

Activation of naïve CD4+ T cells re-tunes STAT1 signaling to deliver unique cytokine responses in memory CD4+ T cells

Altered major histocompatibility complex class II peptide loading in H2-O-deficient mice

Analysis of mannose receptor regulation by IL-4, IL-10, and proteolytic processing using novel monoclonal antibodies

Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1.

Anticancer chemotherapy-induced intratumoral recruitment and differentiation of antigen-presenting cells

Antigen targeting reveals splenic CD169+ macrophages as promoters of germinal center B-cell responses

CD200 receptor restriction of myeloid cell responses antagonizes antiviral immunity and facilitates cytomegalovirus persistence within mucosal tissue

CLEC-2 is a phagocytic activation receptor expressed on murine peripheral blood neutrophils.

Characterisation of murine MICL (CLEC12A) and evidence for an endogenous ligand

Class IA phosphoinositide 3-kinase β and δ regulate neutrophil oxidase activation in response to Aspergillus fumigatus hyphae

Cloning of the mouse homolog of the 126-kDa human C1q/MBL/SP-A receptor, C1qR(p)

Complement C3 plays an essential role in the control of opportunistic fungal infections

Complement contributes to protective immunity against reinfection by Plasmodium chabaudi chabaudi parasites.

Cytosolic phospholipase a2 activation by Candida albicans in alveolar macrophages: role of dectin-1.

Dectin-1 is required for beta-glucan recognition and control of fungal infection

Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection

Dectin-2 is predominantly myeloid restricted and exhibits unique activation-dependent expression on maturing inflammatory monocytes elicited in vivo

Dependence on Dectin-1 Varies With Multiple Candida Species

Development and characterization of novel anti-C5 monoclonal antibodies capable of inhibiting complement in multiple species

Development of a specific system for targeting protein to metallophilic macrophages

Development of myeloproliferative disease in 12/15-lipoxygenase deficiency

Differential dependencies of monocytes and neutrophils on dectin-1, dectin-2 and complement for the recognition of fungal particles in inflammation

Distinct bone marrow-derived and tissue-resident macrophage lineages proliferate at key stages during inflammation

Effective In Vivo Gene Modification in Mouse Tissue-Resident Peritoneal Macrophages by Intraperitoneal Delivery of Lentiviral Vectors

Endogenous oncogenic Nras mutation promotes aberrant GM-CSF signaling in granulocytic/monocytic precursors in a murine model of chronic myelomonocytic leukemia

Esterified eicosanoids are acutely generated by 5-lipoxygenase in primary human neutrophils and in human and murine infection

Expression of the beta-glucan receptor, Dectin-1, on murine leukocytes in situ correlates with its function in pathogen recognition and reveals potential roles in leukocyte interactions

Fungal recognition enhances mannose receptor shedding through dectin-1 engagement

Hoxb8 conditionally immortalised macrophage lines model inflammatory monocytic cells with important similarity to dendritic cells

IL-10 differentially controls the infiltration of inflammatory macrophages and antigen-presenting cells during inflammation

In vivo functional analysis and genetic modification of in vitro-derived mouse neutrophils

Innate immune response to human bone marrow fibroblastic cell implantation in CB17 scid/beige mice

Integrin CD11b positively regulates TLR4-induced signalling pathways in dendritic cells but not in macrophages

Interleukin-10 regulates the inflammasome-driven augmentation of inflammatory arthritis and joint destruction

Interleukin-6 limits influenza-induced inflammation and protects against fatal lung pathology

Interleukin-6 signaling drives fibrosis in unresolved inflammation

LAB/NTAL facilitates fungal/PAMP-induced IL-12 and IFN-γ production by repressing β-catenin activation in dendritic cells

Macrophage Reprogramming for Therapy

Monocyte and macrophage heterogeneity

Monocyte heterogeneity and innate immunity

Murine D17H6S45 (Rd) gene: polymorphism and overlap with complement factor B.

NR4A orphan nuclear receptor family members, NR4A2 and NR4A3, regulate neutrophil number and survival

Networks of enzymatically oxidized membrane lipids support calcium-dependent coagulation factor binding to maintain hemostasis.

Neutrophils recruited by IL-22 in peripheral tissues function as TRAIL-dependent antiviral effectors against MCMV.

Oxylipin metabolism is controlled by mitochondrial β-oxidation during bacterial inflammation

PIP2 depletion and altered endocytosis caused by expression of Alzheimer's disease-protective variant PLCγ2 R522

Paracetamol reduces influenza-induced immunopathology in a mouse model of infection without compromising virus clearance or the generation of protective immunity

Pathways regulating cytosolic phospholipase A2 activation and eicosanoid production in macrophages by Candida albicans

Pattern recognition receptors and differentiation antigens define murine myeloid cell heterogeneity ex vivo

Peritoneal tissue-resident macrophages are metabolically poised to engage microbes using tissue-niche fuels

Phagocytosis is the main CR3-mediated function affected by the lupus-associated variant of CD11b in human myeloid cells

Phosphatidylethanolamine-esterified eicosanoids in the mouse: tissue localization and inflammation-dependent formation in Th-2 disease

RNA interference mutant induction in vivo demonstrates the essential nature of trypanosome flagellar function during mammalian infection

Recognition of bacterial capsular polysaccharides and lipopolysaccharides by the macrophage mannose receptor

Regulation of cytosolic phospholipase A2 activation and cyclooxygenase 2 expression in macrophages by the beta-glucan receptor

Restoration of pattern recognition receptor costimulation to treat chromoblastomycosis, a chronic fungal infection of the skin

Soluble Dectin-1 as a tool to detect beta-glucans

Stage-specific sampling by pattern recognition receptors during Candida albicans phagocytosis

Structural and Functional Analyses of the Shedding Protease ADAM17 in HoxB8-Immortalized Macrophages and Dendritic-like Cells

Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors.

Systemic lupus erythematosus, complement deficiency, and apoptosis

The C-type lectin SIGNR1 binds Schistosoma mansoni antigens in vitro, but SIGNR1-deficient mice have normal responses during schistosome infection

The carbohydrate-recognition domain of Dectin-2 is a C-type lectin with specificity for high mannose

The contribution of naturally occurring IgM antibodies, IgM cross-reactivity and complement dependency in murine humoral responses to pneumococcal capsular polysaccharides

The mannose receptor: linking homeostasis and immunity through sugar recognition

The myeloid 7/4-antigen defines recently generated inflammatory macrophages and is synonymous with Ly-6B.

The protective effect of inflammatory monocytes during systemic C. albicans infection is dependent on collaboration between C-type lectin-like receptors

The transcription factor Gata6 links tissue macrophage phenotype and proliferative renewal

Tissue-resident macrophages

Tissue-resident macrophages actively suppress IL-1beta release via a reactive prostanoid/IL-10 pathway

Tissue-resident macrophages: then and now.

Understanding local macrophage phenotypes in disease: shape-shifting macrophages

miR-192 induces G2/M growth arrest in aristolochic acid nephropathy

miR-21 Promotes Fibrogenesis in Peritoneal Dialysis