Lista de obras - Deborah H. Spector - Dominio Público Uruguay

25-Hydroxycholesterol activates the integrated stress response to reprogram transcription and translation in macrophages

artículo científico publicado en 2013

A human cytomegalovirus-encoded microRNA regulates expression of multiple viral genes involved in replication

artículo científico publicado en 2007

A mutation deleting sequences encoding the amino terminus of human cytomegalovirus UL84 impairs interaction with UL44 and capsid localization

artículo científico publicado en 2012

Characteristics of cellular RNA related to the transforming gene of avian sarcoma viruses

artículo científico publicado en 1978

Cloning, characterization, and expression of the murine cytomegalovirus homologue of the human cytomegalovirus 28-kDa matrix phosphoprotein (UL99).

artículo científico publicado en 1994

Cyclin-dependent kinase activity is required at early times for accurate processing and accumulation of the human cytomegalovirus UL122-123 and UL37 immediate-early transcripts and at later times for virus production

artículo científico publicado en 2004

Cytomegalovirus Activates Interferon Immediate-Early Response Gene Expression and an Interferon Regulatory Factor 3-Containing Interferon-Stimulated Response Element-Binding Complex ⬇️

artículo científico publicado el 1 de julio de 1998

DNA immunization using highly conserved murine cytomegalovirus genes encoding homologs of human cytomegalovirus UL54 (DNA polymerase) and UL105 (helicase) elicits strong CD8 T-cell responses and is protective against systemic challenge.

artículo científico publicado en 2007

Development of a vaccine against murine cytomegalovirus (MCMV), consisting of plasmid DNA and formalin-inactivated MCMV, that provides long-term, complete protection against viral replication

artículo científico publicado en 2002

Early CMV gene expression and function

article

Exon 3 of the human cytomegalovirus major immediate-early region is required for efficient viral gene expression and for cellular cyclin modulation.

artículo científico publicado en 2005

Heterogeneity of genetic loci in chickens: analysis of endogenous viral and nonviral genes by cleavage of DNA with restriction endonucleases

artículo científico publicado en 1979

Human Cytomegalovirus Replication is Inhibited by the Autophagy-Inducing Compounds Trehalose and SMER28 Through Distinctively Different Mechanisms.

artículo científico publicado en 2017

Human cytomegalovirus IE2 86 and IE2 40 proteins differentially regulate UL84 protein expression posttranscriptionally in the absence of other viral gene products.

artículo científico publicado en 2010

Human cytomegalovirus early gene expression

artículo científico publicado en 1990

Human cytomegalovirus infection leads to accumulation of geminin and inhibition of the licensing of cellular DNA replication

artículo científico publicado en 2003

Human cytomegalovirus infection of human embryonic stem cell-derived primitive neural stem cells is restricted at several steps but leads to the persistence of viral DNA.

artículo científico publicado en 2014

Human cytomegalovirus riding the cell cycle.

artículo científico

IUGR and congenital cytomegalovirus infection

artículo científico publicado en 2014

Immunization with herpes simplex virus 2 (HSV-2) genes plus inactivated HSV-2 is highly protective against acute and recurrent HSV-2 disease

artículo científico publicado en 2011

In vivo and in vitro analysis of transcriptional activation mediated by the human cytomegalovirus major immediate-early proteins.

artículo científico publicado en 1993

Inactivated HSV-2 in MPL/alum adjuvant provides nearly complete protection against genital infection and shedding following long term challenge and rechallenge ⬇️

artículo científico publicado el 12 de octubre de 2012

Inactivation and disassembly of the anaphase-promoting complex during human cytomegalovirus infection is associated with degradation of the APC5 and APC4 subunits and does not require UL97-mediated phosphorylation of Cdh1.

artículo científico publicado en 2010

Infection of vascular endothelial cells with human cytomegalovirus under fluid shear stress reveals preferential entry and spread of virus in flow conditions simulating atheroprone regions of the artery

artículo científico publicado en 2012

Inhibition of the cyclin-dependent kinases at the beginning of human cytomegalovirus infection specifically alters the levels and localization of the RNA polymerase II carboxyl-terminal domain kinases cdk9 and cdk7 at the viral transcriptosome

artículo científico publicado en 2007

Mechanisms governing maintenance of Cdk1/cyclin B1 kinase activity in cells infected with human cytomegalovirus

artículo científico publicado en 2003

Molecular cloning and restriction endonuclease mapping of the murine cytomegalovirus genome (Smith strain)

artículo científico publicado en 1983

Multiple epitopes in the murine cytomegalovirus early gene product M84 are efficiently presented in infected primary macrophages and contribute to strong CD8+-T-lymphocyte responses and protection following DNA immunization

artículo científico publicado en 2004

Mutation of glutamine to arginine at position 548 of IE2 86 in human cytomegalovirus leads to decreased expression of IE2 40, IE2 60, UL83, and UL84 and increased transcription of US8-9 and US29-32.

artículo científico publicado en 2011

Nuclear export of the human cytomegalovirus tegument protein pp65 requires cyclin-dependent kinase activity and the Crm1 exporter

artículo científico publicado en 2007

POSITIVE AND NEGATIVE EFFECTS OF HUMAN CYTOMEGALOVIRUS ON HIV REPLICATION

article

Polyadenylic acid on poliovirus RNA IV. Poly(U) in replicative intermediate and double-stranded RNA.

artículo científico publicado en 1975

Post-transcriptional control of avian oncornavirus transforming gene sequences in mammalian cells ⬇️

artículo científico publicado el 8 de septiembre de 1977

Proteasome subunits relocalize during human cytomegalovirus infection, and proteasome activity is necessary for efficient viral gene transcription

artículo científico publicado en 2009

Proviruses of avian sarcoma virus are terminally redundant, co-extensive with unintegrated linear DNA and integrated at many sites

artículo científico publicado en 1978

Replication of the murine cytomegalovirus genome: structure and role of the termini in the generation and cleavage of concatenates.

artículo científico publicado en 1988

Repression of HMGA2 gene expression by human cytomegalovirus involves the IE2 86-kilodalton protein and is necessary for efficient viral replication and inhibition of cyclin A transcription

artículo científico publicado en 2006

Small internal deletions in the human cytomegalovirus IE2 gene result in nonviable recombinant viruses with differential defects in viral gene expression.

artículo científico publicado en 2004

Specific chromosome 1 breaks induced by human cytomegalovirus.

artículo científico publicado en 2000

Strong CD8 T-cell responses following coimmunization with plasmids expressing the dominant pp89 and subdominant M84 antigens of murine cytomegalovirus correlate with long-term protection against subsequent viral challenge

artículo científico publicado en 2002

Studies of HIV infection and the development of Epstein-Barr virus-related B cell lymphomas following transfer of human lymphocytes to mice with severe combined immunodeficiency

artículo científico publicado en 1989

Studies on the Contribution of Human Cytomegalovirus UL21a and UL97 to Viral Growth and Inactivation of the Anaphase-Promoting Complex/Cyclosome (APC/C) E3 Ubiquitin Ligase Reveal a Unique Cellular Mechanism for Downmodulation of the APC/C Subunits A

artículo científico publicado en 2015

Studies on the function of polyadenylic acid on poliovirus RNA.

artículo científico publicado en 1975

Subversion of cell cycle regulatory pathways

artículo científico publicado en 2008

Systemic priming-boosting immunization with a trivalent plasmid DNA and inactivated murine cytomegalovirus (MCMV) vaccine provides long-term protection against viral replication following systemic or mucosal MCMV challenge

artículo científico publicado en 2005

The IE2 60-kilodalton and 40-kilodalton proteins are dispensable for human cytomegalovirus replication but are required for efficient delayed early and late gene expression and production of infectious virus.

artículo científico publicado en 2007

The use of recombinant baculoviruses for sustained expression of human cytomegalovirus immediate early proteins in fibroblasts.

artículo científico publicado en 2001

Transcription analysis and sequence of the putative murine cytomegalovirus DNA polymerase gene

artículo científico publicado en 1991

Transcription in human fibroblasts permissively infected by human cytomegalovirus strain AD169.

artículo científico publicado en 1983

Transcription in mouse embryo cells permissively infected by murine cytomegalovirus.

artículo científico publicado en 1983

Trehalose, an mTOR-Independent Inducer of Autophagy, Inhibits Human Cytomegalovirus Infection in Multiple Cell Types

artículo científico publicado en 2015

Uninfected avian cells contain RNA related to the transforming gene of avian sarcoma viruses

artículo científico publicado en 1978

Viral induction of site-specific chromosome damage.

artículo científico publicado en 2003

Zika virus is transmitted in neural progenitor cells via cell-to-cell spread and infection is inhibited by the autophagy inducer trehalose

artículo científico publicado en 2020

Lista de obras de Deborah H. Spector

25-Hydroxycholesterol activates the integrated stress response to reprogram transcription and translation in macrophages

A human cytomegalovirus-encoded microRNA regulates expression of multiple viral genes involved in replication

A mutation deleting sequences encoding the amino terminus of human cytomegalovirus UL84 impairs interaction with UL44 and capsid localization

Characteristics of cellular RNA related to the transforming gene of avian sarcoma viruses

Cloning, characterization, and expression of the murine cytomegalovirus homologue of the human cytomegalovirus 28-kDa matrix phosphoprotein (UL99).

Cyclin-dependent kinase activity is required at early times for accurate processing and accumulation of the human cytomegalovirus UL122-123 and UL37 immediate-early transcripts and at later times for virus production

Cytomegalovirus Activates Interferon Immediate-Early Response Gene Expression and an Interferon Regulatory Factor 3-Containing Interferon-Stimulated Response Element-Binding Complex ⬇️

DNA immunization using highly conserved murine cytomegalovirus genes encoding homologs of human cytomegalovirus UL54 (DNA polymerase) and UL105 (helicase) elicits strong CD8 T-cell responses and is protective against systemic challenge.

Development of a vaccine against murine cytomegalovirus (MCMV), consisting of plasmid DNA and formalin-inactivated MCMV, that provides long-term, complete protection against viral replication

Early CMV gene expression and function

Exon 3 of the human cytomegalovirus major immediate-early region is required for efficient viral gene expression and for cellular cyclin modulation.

Heterogeneity of genetic loci in chickens: analysis of endogenous viral and nonviral genes by cleavage of DNA with restriction endonucleases

Human Cytomegalovirus Replication is Inhibited by the Autophagy-Inducing Compounds Trehalose and SMER28 Through Distinctively Different Mechanisms.

Human cytomegalovirus IE2 86 and IE2 40 proteins differentially regulate UL84 protein expression posttranscriptionally in the absence of other viral gene products.

Human cytomegalovirus early gene expression

Human cytomegalovirus infection leads to accumulation of geminin and inhibition of the licensing of cellular DNA replication

Human cytomegalovirus infection of human embryonic stem cell-derived primitive neural stem cells is restricted at several steps but leads to the persistence of viral DNA.

Human cytomegalovirus riding the cell cycle.

IUGR and congenital cytomegalovirus infection

Immunization with herpes simplex virus 2 (HSV-2) genes plus inactivated HSV-2 is highly protective against acute and recurrent HSV-2 disease

In vivo and in vitro analysis of transcriptional activation mediated by the human cytomegalovirus major immediate-early proteins.

Inactivated HSV-2 in MPL/alum adjuvant provides nearly complete protection against genital infection and shedding following long term challenge and rechallenge ⬇️

Inactivation and disassembly of the anaphase-promoting complex during human cytomegalovirus infection is associated with degradation of the APC5 and APC4 subunits and does not require UL97-mediated phosphorylation of Cdh1.

Infection of vascular endothelial cells with human cytomegalovirus under fluid shear stress reveals preferential entry and spread of virus in flow conditions simulating atheroprone regions of the artery

Inhibition of the cyclin-dependent kinases at the beginning of human cytomegalovirus infection specifically alters the levels and localization of the RNA polymerase II carboxyl-terminal domain kinases cdk9 and cdk7 at the viral transcriptosome

Mechanisms governing maintenance of Cdk1/cyclin B1 kinase activity in cells infected with human cytomegalovirus

Molecular cloning and restriction endonuclease mapping of the murine cytomegalovirus genome (Smith strain)

Multiple epitopes in the murine cytomegalovirus early gene product M84 are efficiently presented in infected primary macrophages and contribute to strong CD8+-T-lymphocyte responses and protection following DNA immunization

Mutation of glutamine to arginine at position 548 of IE2 86 in human cytomegalovirus leads to decreased expression of IE2 40, IE2 60, UL83, and UL84 and increased transcription of US8-9 and US29-32.

Nuclear export of the human cytomegalovirus tegument protein pp65 requires cyclin-dependent kinase activity and the Crm1 exporter

POSITIVE AND NEGATIVE EFFECTS OF HUMAN CYTOMEGALOVIRUS ON HIV REPLICATION

Polyadenylic acid on poliovirus RNA IV. Poly(U) in replicative intermediate and double-stranded RNA.

Post-transcriptional control of avian oncornavirus transforming gene sequences in mammalian cells ⬇️

Proteasome subunits relocalize during human cytomegalovirus infection, and proteasome activity is necessary for efficient viral gene transcription

Proviruses of avian sarcoma virus are terminally redundant, co-extensive with unintegrated linear DNA and integrated at many sites

Replication of the murine cytomegalovirus genome: structure and role of the termini in the generation and cleavage of concatenates.

Repression of HMGA2 gene expression by human cytomegalovirus involves the IE2 86-kilodalton protein and is necessary for efficient viral replication and inhibition of cyclin A transcription

Small internal deletions in the human cytomegalovirus IE2 gene result in nonviable recombinant viruses with differential defects in viral gene expression.

Specific chromosome 1 breaks induced by human cytomegalovirus.

Strong CD8 T-cell responses following coimmunization with plasmids expressing the dominant pp89 and subdominant M84 antigens of murine cytomegalovirus correlate with long-term protection against subsequent viral challenge

Studies of HIV infection and the development of Epstein-Barr virus-related B cell lymphomas following transfer of human lymphocytes to mice with severe combined immunodeficiency

Studies on the Contribution of Human Cytomegalovirus UL21a and UL97 to Viral Growth and Inactivation of the Anaphase-Promoting Complex/Cyclosome (APC/C) E3 Ubiquitin Ligase Reveal a Unique Cellular Mechanism for Downmodulation of the APC/C Subunits A

Studies on the function of polyadenylic acid on poliovirus RNA.

Subversion of cell cycle regulatory pathways

Systemic priming-boosting immunization with a trivalent plasmid DNA and inactivated murine cytomegalovirus (MCMV) vaccine provides long-term protection against viral replication following systemic or mucosal MCMV challenge

The IE2 60-kilodalton and 40-kilodalton proteins are dispensable for human cytomegalovirus replication but are required for efficient delayed early and late gene expression and production of infectious virus.

The use of recombinant baculoviruses for sustained expression of human cytomegalovirus immediate early proteins in fibroblasts.

Transcription analysis and sequence of the putative murine cytomegalovirus DNA polymerase gene

Transcription in human fibroblasts permissively infected by human cytomegalovirus strain AD169.

Transcription in mouse embryo cells permissively infected by murine cytomegalovirus.

Trehalose, an mTOR-Independent Inducer of Autophagy, Inhibits Human Cytomegalovirus Infection in Multiple Cell Types

Uninfected avian cells contain RNA related to the transforming gene of avian sarcoma viruses

Viral induction of site-specific chromosome damage.

Zika virus is transmitted in neural progenitor cells via cell-to-cell spread and infection is inhibited by the autophagy inducer trehalose