Lista de obras - Cleo Kontoravdi - Dominio Público Uruguay

A dynamic mathematical model for monoclonal antibody N-linked glycosylation and nucleotide sugar donor transport within a maturing Golgi apparatus

artículo científico publicado en 2011

A framework for the systematic design of fed-batch strategies in mammalian cell culture.

artículo científico publicado en 2014

A multi-pronged investigation into the effect of glucose starvation and culture duration on fed-batch CHO cell culture

artículo científico publicado en 2015

A systems biology approach to optimising hosts for industrial protein production.

artículo científico

Amino acid and glucose metabolism in fed-batch CHO cell culture affects antibody production and glycosylation

artículo científico publicado en 2014

An experimental approach probing the conformational transitions and energy landscape of antibodies: a glimmer of hope for reviving lost therapeutic candidates using ionic liquid

artículo científico publicado en 2021

An optimized method for extraction and quantification of nucleotides and nucleotide sugars from mammalian cells

artículo científico publicado en 2013

Analysis of Chinese hamster ovary cell metabolism through a combined computational and experimental approach

artículo científico publicado en 2013

Analysis of the landscape of biologically-derived pharmaceuticals in Europe: dominant production systems, molecule types on the rise and approval trends.

artículo científico publicado en 2012

Application of global sensitivity analysis to determine goals for design of experiments: an example study on antibody-producing cell cultures

artículo científico publicado en 2005

Cascading effect in bioprocessing-The impact of mild hypothermia on CHO cell behavior and host cell protein composition

artículo científico publicado en 2017

Comparative analysis of amino acid metabolism and transport in CHO variants with different levels of productivity.

artículo científico publicado en 2013

Development and design of bio-pharmaceutical processes

artículo científico publicado en 2013

Dynamic profiling of amino acid transport and metabolism in Chinese hamster ovary cell culture

artículo científico publicado en 2013

Exploring cellular behavior under transient gene expression and its impact on mAb productivity and Fc-glycosylation

artículo científico publicado en 2017

Genetically-encoded biosensors for monitoring cellular stress in bioprocessing.

artículo científico publicado en 2014

Genome-based kinetic modeling of cytosolic glucose metabolism in industrially relevant cell lines: Saccharomyces cerevisiae and Chinese hamster ovary cells.

artículo científico publicado en 2012

Global sensitivity analysis and meta-modeling of an ethanol production process

artículo científico publicado en 2014

Host cell protein removal from biopharmaceutical preparations: Towards the implementation of quality by design

artículo científico publicado en 2018

How does mild hypothermia affect monoclonal antibody glycosylation?

artículo científico publicado en 2015

In Situ Monitoring of Intracellular Glucose and Glutamine in CHO Cell Culture ⬇️

artículo científico publicado el 3 de abril de 2012

Integration of models and experimentation to optimise the production of potential biotherapeutics ⬇️

artículo científico publicado el 9 de julio de 2013

Metabolic characterization and modeling of fermentation process of an engineered Geobacillus thermoglucosidasius strain for bioethanol production with gas stripping

artículo científico publicado en 2015

Metabolic network reconstruction: advances in in silico interpretation of analytical information ⬇️

artículo científico publicado el 24 de noviembre de 2011

Model-based investigation of intracellular processes determining antibody Fc-glycosylation under mild hypothermia.

artículo científico publicado en 2016

Model-based optimization of antibody galactosylation in CHO cell culture

artículo científico publicado en 2019

Modeling amino acid metabolism in mammalian cells-toward the development of a model library

artículo científico publicado en 2007

Quantification of intracellular nucleotide sugars and formulation of a mathematical model for prediction of their metabolism ⬇️

artículo científico publicado el 22 de noviembre de 2011

Resources, Production Scales and Time Required for Producing RNA Vaccines for the Global Pandemic Demand

artículo científico publicado en 2020

Systematic Methodology for the Development of Mathematical Models for Biological Processes ⬇️

artículo científico publicado el 1 de enero de 2013

The role of ER stress-induced apoptosis in neurodegeneration.

artículo científico

Towards controlling the glycoform: a model framework linking extracellular metabolites to antibody glycosylation

artículo científico publicado en 2014

Towards the implementation of quality by design to the production of therapeutic monoclonal antibodies with desired glycosylation patterns

artículo científico publicado en 2010

Lista de obras de Cleo Kontoravdi

A dynamic mathematical model for monoclonal antibody N-linked glycosylation and nucleotide sugar donor transport within a maturing Golgi apparatus

A framework for the systematic design of fed-batch strategies in mammalian cell culture.

A multi-pronged investigation into the effect of glucose starvation and culture duration on fed-batch CHO cell culture

A systems biology approach to optimising hosts for industrial protein production.

Amino acid and glucose metabolism in fed-batch CHO cell culture affects antibody production and glycosylation

An experimental approach probing the conformational transitions and energy landscape of antibodies: a glimmer of hope for reviving lost therapeutic candidates using ionic liquid

An optimized method for extraction and quantification of nucleotides and nucleotide sugars from mammalian cells

Analysis of Chinese hamster ovary cell metabolism through a combined computational and experimental approach

Analysis of the landscape of biologically-derived pharmaceuticals in Europe: dominant production systems, molecule types on the rise and approval trends.

Application of global sensitivity analysis to determine goals for design of experiments: an example study on antibody-producing cell cultures

Cascading effect in bioprocessing-The impact of mild hypothermia on CHO cell behavior and host cell protein composition

Comparative analysis of amino acid metabolism and transport in CHO variants with different levels of productivity.

Development and design of bio-pharmaceutical processes

Dynamic profiling of amino acid transport and metabolism in Chinese hamster ovary cell culture

Exploring cellular behavior under transient gene expression and its impact on mAb productivity and Fc-glycosylation

Genetically-encoded biosensors for monitoring cellular stress in bioprocessing.

Genome-based kinetic modeling of cytosolic glucose metabolism in industrially relevant cell lines: Saccharomyces cerevisiae and Chinese hamster ovary cells.

Global sensitivity analysis and meta-modeling of an ethanol production process

Host cell protein removal from biopharmaceutical preparations: Towards the implementation of quality by design

How does mild hypothermia affect monoclonal antibody glycosylation?

In Situ Monitoring of Intracellular Glucose and Glutamine in CHO Cell Culture ⬇️

Integration of models and experimentation to optimise the production of potential biotherapeutics ⬇️

Metabolic characterization and modeling of fermentation process of an engineered Geobacillus thermoglucosidasius strain for bioethanol production with gas stripping

Metabolic network reconstruction: advances in in silico interpretation of analytical information ⬇️

Model-based investigation of intracellular processes determining antibody Fc-glycosylation under mild hypothermia.

Model-based optimization of antibody galactosylation in CHO cell culture

Modeling amino acid metabolism in mammalian cells-toward the development of a model library

Quantification of intracellular nucleotide sugars and formulation of a mathematical model for prediction of their metabolism ⬇️

Resources, Production Scales and Time Required for Producing RNA Vaccines for the Global Pandemic Demand

Systematic Methodology for the Development of Mathematical Models for Biological Processes ⬇️

The role of ER stress-induced apoptosis in neurodegeneration.

Towards controlling the glycoform: a model framework linking extracellular metabolites to antibody glycosylation

Towards the implementation of quality by design to the production of therapeutic monoclonal antibodies with desired glycosylation patterns