Lista de obras - Sébastien Wälchli - Dominio Público Uruguay

A Spheroid Killing Assay by CAR T Cells

scientific article published on 12 December 2018

A TCR-based Chimeric Antigen Receptor

artículo científico publicado en 2017

A catalogue of Ovarian Cancer targets for CAR therapy

scientific article published on 17 June 2020

A practical approach to T-cell receptor cloning and expression

artículo científico publicado en 2011

A single point mutation in ricin A-chain increases toxin degradation and inhibits EDEM1-dependent ER retrotranslocation

artículo científico publicado en 2011

Alloreactive cytotoxic T cells provide means to decipher the immunopeptidome and reveal a plethora of tumor-associated self-epitopes.

artículo científico publicado en 2013

Antigen-delivery through invariant chain (CD74) boosts CD8 and CD4 T cell immunity

artículo científico publicado en 2019

Artesunate shows potent anti-tumor activity in B-cell lymphoma

artículo científico publicado en 2018

Axonal guidance protein FEZ1 associates with tubulin and kinesin motor protein to transport mitochondria in neurites of NGF-stimulated PC12 cells

scientific journal article

BMP-7 induces apoptosis in human germinal center B cells and is influenced by TGF-β receptor type I ALK5

artículo científico publicado en 2017

BiP negatively affects ricin transport

artículo científico publicado en 2013

Breadth and Dynamics of HLA-A2- and HLA-B7-Restricted CD8+ T Cell Responses against Nonstructural Viral Proteins in Acute Human Tick-Borne Encephalitis Virus Infection

scientific article published on 02 July 2018

Characterization of clathrin and Syk interaction upon Shiga toxin binding

artículo científico publicado en 2009

Colorectal cysts as a validating tool for CAR therapy

artículo científico publicado en 2020

Combinatorial CAR design improves target restriction

artículo científico publicado en 2020

Correction to: Preclinical assessment of transiently TCR redirected T cells for solid tumour immunotherapy

artículo científico publicado en 2020

Deciphering the Nongenomic, Mitochondrial Toxicity of Tamoxifens As Determined by Cell Metabolism and Redox Activity.

artículo científico publicado en 2015

Dendritic cells engineered to express defined allo-HLA peptide complexes induce antigen-specific cytotoxic T cells efficiently killing tumour cells.

artículo científico publicado en 2009

Distinct patterns of B-cell receptor signaling in non-Hodgkin lymphomas identified by single-cell profiling

artículo científico publicado en 2016

EDEM is involved in retrotranslocation of ricin from the endoplasmic reticulum to the cytosol

artículo científico publicado en 2006

Enhancing Antitumor Immune Responses by Optimized Combinations of Cell-penetrating Peptide-based Vaccines and Adjuvants

artículo científico publicado en 2016

Enigma homolog 1 scaffolds protein kinase D1 to regulate the activity of the cardiac L-type voltage-gated calcium channel

artículo científico publicado en 2008

Gene Editing in B-Lymphoma Cell Lines Using CRISPR/Cas9 Technology

artículo científico publicado en 2020

Glycosphingolipid requirements for endosome-to-Golgi transport of Shiga toxin.

artículo científico publicado en 2009

Golgi vesiculation induced by cholesterol occurs by a dynamin- and cPLA2-dependent mechanism

artículo científico publicado en 2005

Human c-SRC kinase (CSK) overexpression makes T cells dummy.

artículo científico publicado en 2017

Identification of protein tyrosine phosphatases with specificity for the ligand-activated growth hormone receptor

artículo científico publicado en 2003

Identification of tyrosine phosphatases that dephosphorylate the insulin receptor. A brute force approach based on "substrate-trapping" mutants

artículo científico publicado en 2000

Invariant chain as a vehicle to load antigenic peptides on human MHC class I for cytotoxic T-cell activation.

artículo científico publicado en 2013

Long-term surviving cancer patients as a source of therapeutic TCR

artículo científico publicado en 2020

Mapping of synergistic components of weakly interacting protein-protein motifs using arrays of paired peptides

artículo científico publicado en 2003

MetaBlasts: tracing protein tyrosine phosphatase gene family roots from Man to Drosophila melanogaster and Caenorhabditis elegans genomes.

artículo científico publicado en 2000

NK cells specifically TCR-dressed to kill cancer cells

Next Generation of Adoptive T Cell Therapy Using CRISPR/Cas9 Technology: Universal or Boosted?

artículo científico publicado en 2020

Phosphoinositide-regulated retrograde transport of ricin: crosstalk between hVps34 and sorting nexins

artículo científico publicado en 2007

Phosphorylation of fibroblast growth factor (FGF) receptor 1 at Ser777 by p38 mitogen-activated protein kinase regulates translocation of exogenous FGF1 to the cytosol and nucleus

artículo científico publicado en 2008

Preclinical assessment of transiently TCR redirected T cells for solid tumour immunotherapy

artículo científico publicado en 2019

Preclinical development of CD37CAR T-cell therapy for treatment of B-cell lymphoma

article

Probing protein-tyrosine phosphatase substrate specificity using a phosphotyrosine-containing phage library

artículo científico publicado en 2003

Protein kinase Cdelta is activated by Shiga toxin and regulates its transport.

artículo científico publicado en 2007

Protein tyrosine phosphatases as drug targets: PTP1B and beyond

artículo científico publicado en 2002

Rab7b regulates dendritic cell migration by linking lysosomes to the actomyosin cytoskeleton

artículo científico publicado en 2021

Reconstitution of active diphtheria toxin based on a hexahistidine tagged version of the B-fragment produced to high yields in bacteria

artículo científico publicado en 2005

Role of Smad proteins in resistance to BMP-induced growth inhibition in B-cell lymphoma

artículo científico publicado en 2012

SNX4 in complex with clathrin and dynein: implications for endosome movement

artículo científico publicado en 2009

Sap-1/PTPRH activity is regulated by reversible dimerization

artículo científico publicado en 2005

Shiga toxin regulates its entry in a Syk-dependent manner

artículo científico publicado en 2005

Simultaneous defeat of MCF7 and MDA-MB-231 resistances by a hypericin PDT-tamoxifen hybrid therapy

scientific article published on 10 April 2019

Soluble T-cell receptors produced in human cells for targeted delivery.

artículo científico publicado en 2015

Splice variants of enigma homolog, differentially expressed during heart development, promote or prevent hypertrophy

artículo científico publicado en 2010

Strategies for the design of random siRNA libraries and the selection of anti-GFP siRNAs

artículo científico publicado en 2005

Sympathetic improvement of cancer vaccine efficacy

scientific article published on 24 January 2020

T cell therapy targeting a public neoantigen in microsatellite instable colon cancer reduces in vivo tumor growth

artículo científico publicado en 2017

T cells raised against allogeneic HLA-A2/CD20 kill primary follicular lymphoma and acute lymphoblastic leukemia cells

artículo científico publicado en 2011

T-cell receptor therapy (TCR) against melanoma -immunotherapy for the future?

artículo científico publicado en 2020

T-helper cell receptors from long-term survivors after telomerase cancer vaccination for use in adoptive cell therapy

artículo científico publicado en 2016

TIGIT and PD-1 Mark Intratumoral T Cells with Reduced Effector Function in B-cell Non-Hodgkin Lymphoma

scientific article published on 18 January 2019

Targeting B cell leukemia with highly specific allogeneic T cells with a public recognition motif

artículo científico publicado en 2010

Targeting B-cell neoplasia with T-cell receptors recognizing a CD20-derived peptide on patient-specific HLA

artículo científico publicado en 2016

Targeting telomerase with an HLA class II-restricted TCR for cancer immunotherapy

artículo científico publicado en 2020

The ESCRT-III subunit hVps24 is required for degradation but not silencing of the epidermal growth factor receptor.

artículo científico publicado en 2006

The Mitogen-activated protein kinase p38 links Shiga Toxin-dependent signaling and trafficking

artículo científico publicado en 2007

The disulfide isomerase Grp58 is a protective factor against prion neurotoxicity.

artículo científico publicado en 2005

Transcriptional targeting of small interfering RNAs into cancer cells

artículo científico publicado en 2006

Transiently redirected T cells for adoptive transfer.

artículo científico publicado en 2010

Transport of ricin from endosomes to the Golgi apparatus is regulated by Rab6A and Rab6A'.

artículo científico publicado en 2006

Treating osteosarcoma with CAR T cells

scientific article published on 15 January 2019

Unpredicted phenotypes of two mutants of the TcR DMF5.

artículo científico publicado en 2015

Vector-based delivery of siRNAs: in vitro and in vivo challenges.

artículo científico publicado en 2008

beta-catenin is involved in N-cadherin-dependent adhesion, but not in canonical Wnt signaling in E2A-PBX1-positive B acute lymphoblastic leukemia cells

artículo científico publicado en 2009

β-arrestins attenuate p38-mediated endosome to Golgi transport.

artículo científico publicado en 2009

Lista de obras de Sébastien Wälchli

A Spheroid Killing Assay by CAR T Cells

A TCR-based Chimeric Antigen Receptor

A catalogue of Ovarian Cancer targets for CAR therapy

A practical approach to T-cell receptor cloning and expression

A single point mutation in ricin A-chain increases toxin degradation and inhibits EDEM1-dependent ER retrotranslocation

Alloreactive cytotoxic T cells provide means to decipher the immunopeptidome and reveal a plethora of tumor-associated self-epitopes.

Antigen-delivery through invariant chain (CD74) boosts CD8 and CD4 T cell immunity

Artesunate shows potent anti-tumor activity in B-cell lymphoma

Axonal guidance protein FEZ1 associates with tubulin and kinesin motor protein to transport mitochondria in neurites of NGF-stimulated PC12 cells

BMP-7 induces apoptosis in human germinal center B cells and is influenced by TGF-β receptor type I ALK5

BiP negatively affects ricin transport

Breadth and Dynamics of HLA-A2- and HLA-B7-Restricted CD8+ T Cell Responses against Nonstructural Viral Proteins in Acute Human Tick-Borne Encephalitis Virus Infection

Characterization of clathrin and Syk interaction upon Shiga toxin binding

Colorectal cysts as a validating tool for CAR therapy

Combinatorial CAR design improves target restriction

Correction to: Preclinical assessment of transiently TCR redirected T cells for solid tumour immunotherapy

Deciphering the Nongenomic, Mitochondrial Toxicity of Tamoxifens As Determined by Cell Metabolism and Redox Activity.

Dendritic cells engineered to express defined allo-HLA peptide complexes induce antigen-specific cytotoxic T cells efficiently killing tumour cells.

Distinct patterns of B-cell receptor signaling in non-Hodgkin lymphomas identified by single-cell profiling

EDEM is involved in retrotranslocation of ricin from the endoplasmic reticulum to the cytosol

Enhancing Antitumor Immune Responses by Optimized Combinations of Cell-penetrating Peptide-based Vaccines and Adjuvants

Enigma homolog 1 scaffolds protein kinase D1 to regulate the activity of the cardiac L-type voltage-gated calcium channel

Gene Editing in B-Lymphoma Cell Lines Using CRISPR/Cas9 Technology

Glycosphingolipid requirements for endosome-to-Golgi transport of Shiga toxin.

Golgi vesiculation induced by cholesterol occurs by a dynamin- and cPLA2-dependent mechanism

Human c-SRC kinase (CSK) overexpression makes T cells dummy.

Identification of protein tyrosine phosphatases with specificity for the ligand-activated growth hormone receptor

Identification of tyrosine phosphatases that dephosphorylate the insulin receptor. A brute force approach based on "substrate-trapping" mutants

Invariant chain as a vehicle to load antigenic peptides on human MHC class I for cytotoxic T-cell activation.

Long-term surviving cancer patients as a source of therapeutic TCR

Mapping of synergistic components of weakly interacting protein-protein motifs using arrays of paired peptides

MetaBlasts: tracing protein tyrosine phosphatase gene family roots from Man to Drosophila melanogaster and Caenorhabditis elegans genomes.

NK cells specifically TCR-dressed to kill cancer cells

Next Generation of Adoptive T Cell Therapy Using CRISPR/Cas9 Technology: Universal or Boosted?

Phosphoinositide-regulated retrograde transport of ricin: crosstalk between hVps34 and sorting nexins

Phosphorylation of fibroblast growth factor (FGF) receptor 1 at Ser777 by p38 mitogen-activated protein kinase regulates translocation of exogenous FGF1 to the cytosol and nucleus

Preclinical assessment of transiently TCR redirected T cells for solid tumour immunotherapy

Preclinical development of CD37CAR T-cell therapy for treatment of B-cell lymphoma

Probing protein-tyrosine phosphatase substrate specificity using a phosphotyrosine-containing phage library

Protein kinase Cdelta is activated by Shiga toxin and regulates its transport.

Protein tyrosine phosphatases as drug targets: PTP1B and beyond

Rab7b regulates dendritic cell migration by linking lysosomes to the actomyosin cytoskeleton

Reconstitution of active diphtheria toxin based on a hexahistidine tagged version of the B-fragment produced to high yields in bacteria

Role of Smad proteins in resistance to BMP-induced growth inhibition in B-cell lymphoma

SNX4 in complex with clathrin and dynein: implications for endosome movement

Sap-1/PTPRH activity is regulated by reversible dimerization

Shiga toxin regulates its entry in a Syk-dependent manner

Simultaneous defeat of MCF7 and MDA-MB-231 resistances by a hypericin PDT-tamoxifen hybrid therapy

Soluble T-cell receptors produced in human cells for targeted delivery.

Splice variants of enigma homolog, differentially expressed during heart development, promote or prevent hypertrophy

Strategies for the design of random siRNA libraries and the selection of anti-GFP siRNAs

Sympathetic improvement of cancer vaccine efficacy

T cell therapy targeting a public neoantigen in microsatellite instable colon cancer reduces in vivo tumor growth

T cells raised against allogeneic HLA-A2/CD20 kill primary follicular lymphoma and acute lymphoblastic leukemia cells

T-cell receptor therapy (TCR) against melanoma -immunotherapy for the future?

T-helper cell receptors from long-term survivors after telomerase cancer vaccination for use in adoptive cell therapy

TIGIT and PD-1 Mark Intratumoral T Cells with Reduced Effector Function in B-cell Non-Hodgkin Lymphoma

Targeting B cell leukemia with highly specific allogeneic T cells with a public recognition motif

Targeting B-cell neoplasia with T-cell receptors recognizing a CD20-derived peptide on patient-specific HLA

Targeting telomerase with an HLA class II-restricted TCR for cancer immunotherapy

The ESCRT-III subunit hVps24 is required for degradation but not silencing of the epidermal growth factor receptor.

The Mitogen-activated protein kinase p38 links Shiga Toxin-dependent signaling and trafficking

The disulfide isomerase Grp58 is a protective factor against prion neurotoxicity.

Transcriptional targeting of small interfering RNAs into cancer cells

Transiently redirected T cells for adoptive transfer.

Transport of ricin from endosomes to the Golgi apparatus is regulated by Rab6A and Rab6A'.

Treating osteosarcoma with CAR T cells

Unpredicted phenotypes of two mutants of the TcR DMF5.

Vector-based delivery of siRNAs: in vitro and in vivo challenges.

beta-catenin is involved in N-cadherin-dependent adhesion, but not in canonical Wnt signaling in E2A-PBX1-positive B acute lymphoblastic leukemia cells

β-arrestins attenuate p38-mediated endosome to Golgi transport.