Lista de obras - Xiang-Peng Kong - Dominio Público Uruguay

A new activity of anti-HIV and anti-tumor protein GAP31: DNA adenosine glycosidase--structural and modeling insight into its functions

artículo científico publicado en 2010

A novel rabbit monoclonal antibody platform to dissect the diverse repertoire of antibody epitopes for HIV-1 Env immunogen design.

artículo científico publicado en 2012

A site of vulnerability at V3 crown defined by HIV-1 bNAb M4008_N1

artículo científico publicado en 2021

AMPA receptor tetramerization is mediated by Q/R editing

artículo científico publicado en 2003

An HIV vaccine targeting the V2 region of Envelope induces a highly durable polyfunctional Fc-mediated antibody response in rhesus macaques

scientific article published on 17 June 2020

An adenosine deaminase (ADA) allele contains two newly identified deleterious mutations (Y97C and L106V) that interact to abolish enzyme activity ⬇️

artículo científico publicado el 1 de diciembre de 1997

An arsenite-inducible 19S regulatory particle-associated protein adapts proteasomes to proteotoxicity

scientific journal article

Antigenic landscape of the HIV-1 envelope and new immunological concepts defined by HIV-1 broadly neutralizing antibodies.

artículo científico publicado en 2016

Antiretroviral Imprints and Genomic Plasticity of HIV-1 <i>pol</i> in Non-clade B: Implications for Treatment

artículo científico publicado en 2021

Atomic force microscopy of Mammalian urothelial surface

artículo científico publicado en 2007

Author Correction: The wide utility of rabbits as models of human diseases

scientific article published on 04 July 2019

Biophysical dissection of the antigen-antibody interaction of the broadly reactive anti-V3 human mAb 447-52D.

artículo científico publicado en 2012

Characteristics of the phagocytic cup induced by uropathogenic Escherichia coli.

artículo científico publicado en 2008

Computational-guided determination of the functional role of 447-52D long CDRH3

artículo científico publicado en 2018

Conserved structural elements in the V3 crown of HIV-1 gp120

artículo científico publicado en 2010

Contrasting antibody responses to intrasubtype superinfection with CRF02_AG.

artículo científico publicado en 2017

Cross-clade HIV-1 neutralizing antibodies induced with V3-scaffold protein immunogens following priming with gp120 DNA.

artículo científico publicado en 2011

Crystal structure analysis of anti-V2 mAb 2158 suggests a conformational epitope involving an N-linked glycan

artículo científico publicado en 2012

Crystal structure of human stem cell factor: implication for stem cell factor receptor dimerization and activation

artículo científico publicado en 2000

Crystallization of Proliferating Cell Nuclear Antigen (PCNA) from Saccharomyces cerevisiae

artículo científico publicado en 1994

Determinants of HIV-1 CD4-independent brain adaptation.

artículo científico publicado en 2017

Differential V2-directed antibody responses in non-human primates infected with SHIVs or immunized with diverse HIV vaccines

artículo científico publicado en 2022

Differential induction of anti-V3 crown antibodies with cradle- and ladle-binding modes in response to HIV-1 envelope vaccination.

artículo científico publicado en 2017

Distinct Glycan Structures of Uroplakins Ia and Ib

scientific article published in Journal of Biological Chemistry

Distinct Residues Contribute to Motility Repression and Autoregulation in the Proteus mirabilis Fimbria-Associated Transcriptional Regulator AtfJ.

artículo científico publicado en 2016

Dual ligand/receptor interactions activate urothelial defenses against uropathogenic E. coli

artículo científico publicado en 2015

Efficiency of bridging-sheet recruitment explains HIV-1 R5 envelope glycoprotein sensitivity to soluble CD4 and macrophage tropism

artículo científico publicado en 2012

Elicitation of broadly reactive antibodies against glycan-modulated neutralizing V3 epitopes of HIV-1 by immune complex vaccines.

artículo científico publicado en 2013

Emergence of SARS-CoV-2 through Recombination and Strong Purifying Selection

artículo científico publicado en 2020

Emergence of SARS-CoV-2 through recombination and strong purifying selection

artículo científico publicado en 2020

Epitope mapping of conformational V2-specific anti-HIV human monoclonal antibodies reveals an immunodominant site in V2.

artículo científico publicado en 2013

Functional Antibody Response Against V1V2 and V3 of HIV gp120 in the VAX003 and VAX004 Vaccine Trials.

artículo científico publicado en 2018

Functional Implications of the Binding Mode of a Human Conformation-Dependent V2 Monoclonal Antibody against HIV

artículo científico publicado en 2014

Functional and Structural Characterization of Human V3-Specific Monoclonal Antibody 2424 with Neutralizing Activity against HIV-1 JRFL

artículo científico publicado en 2015

Functional and immunochemical cross-reactivity of V2-specific monoclonal antibodies from HIV-1-infected individuals

artículo científico publicado en 2012

Gp120 V5 Is Targeted by the First Wave of Sequential Neutralizing Antibodies in SHIVSF162P3N-Infected Rhesus Macaques.

artículo científico publicado en 2018

High-resolution crystal structure of the Fv of quaternary neutralizing epitope mAb 2909 reveals atomic details of its antigen-binding site

Human Anti-V3 HIV-1 Monoclonal Antibodies Encoded by the VH5-51/VL Lambda Genes Define a Conserved Antigenic Structure

artículo científico publicado en 2011

Identification of conserved amino acids in murine B7-1IgV domain critical for CTLA4/CD28:B7 interaction by site-directed mutagenesis: a novel structural model of the binding site.

artículo científico publicado en 1998

Immune Correlates of Disease Progression in Linked HIV-1 Infection

article

Increased epitope complexity correlated with antibody affinity maturation and a novel binding mode revealed by structures of rabbit antibodies against the third variable loop (V3) of HIV-1 gp120.

artículo científico publicado en 2018

Integrity of all four transmembrane domains of the tetraspanin uroplakin Ib is required for its exit from the ER.

artículo científico publicado en 2006

Limonene reduces hyperalgesia induced by gp120 and cytokines by modulation of IL-1 β and protein expression in spinal cord of mice.

artículo científico publicado en 2016

Localization of uroplakin Ia, the urothelial receptor for bacterial adhesin FimH, on the six inner domains of the 16 nm urothelial plaque particle.

artículo científico publicado en 2002

Modulation of Antibody Responses to the V1V2 and V3 Regions of HIV-1 Envelope by Immune Complex Vaccines

article

Multimeric Epitope-Scaffold HIV Vaccines Target V1V2 and Differentially Tune Polyfunctional Antibody Responses

artículo científico publicado en 2019

Organization of uroplakin subunits: transmembrane topology, pair formation and plaque composition

artículo científico publicado en 2001

Priming with DNA expressing trimeric HIV V1V2 alters the immune hierarchy favoring the development of V2-specific antibodies in rhesus macaques

artículo científico publicado en 2020

Rabbit Anti-HIV-1 Monoclonal Antibodies Raised by Immunization Can Mimic the Antigen-Binding Modes of Antibodies Derived from HIV-1-Infected Humans

artículo científico publicado en 2013

Rationally Designed Immunogens Targeting HIV-1 gp120 V1V2 Induce Distinct Conformation-Specific Antibody Responses in Rabbits

artículo científico publicado en 2016

Rationally Designed Vaccines Targeting the V2 Region of HIV-1 gp120 Induce a Focused, Cross-Clade-Reactive, Biologically Functional Antibody Response.

artículo científico publicado en 2016

Rationally Targeted Mutations at the V1V2 Domain of the HIV-1 Envelope to Augment Virus Neutralization by Anti-V1V2 Monoclonal Antibodies.

artículo científico publicado en 2015

Select gp120 V2 domain specific antibodies derived from HIV and SIV infection and vaccination inhibit gp120 binding to α4β7

article

Selective enrichment and fractionation of phosphopeptides from peptide mixtures by isoelectric focusing after methyl esterification

artículo científico publicado en 2007

Sequential and compartmentalized action of Rabs, SNAREs, and MAL in the apical delivery of fusiform vesicles in urothelial umbrella cells

artículo científico publicado en 2016

Sequential exposure to specific antibody escape mutations may program neutralization breadth during subtype A HIV-1 infection

artículo científico publicado en 2012

Sequential trafficking of Env and Gag to HIV-1 T cell virological synapses revealed by live imaging

Signal peptide of HIV-1 envelope modulates glycosylation impacting exposure of V1V2 and other epitopes

artículo científico publicado en 2020

Single genome analysis reveals genetic characteristics of Neuroadaptation across HIV-1 envelope.

artículo científico publicado en 2014

Skin tattooing as a novel approach for DNA vaccine delivery.

artículo científico publicado en 2012

Skin tattooing as an effective tool for delivering DNA and protein vaccine immunogens

artículo científico publicado en 2012

Specificity of staphylococcal phage and SaPI DNA packaging as revealed by integrase and terminase mutations.

artículo científico publicado en 2009

Structural Analysis of Human and Macaque mAbs 2909 and 2.5B: Implications for the Configuration of the Quaternary Neutralizing Epitope of HIV-1 gp120

artículo científico publicado en 2011

Structural Basis of the Cross-Reactivity of Genetically Related Human Anti-HIV-1 mAbs: Implications for Design of V3-Based Immunogens

artículo científico publicado en 2009

Structural Comparison of Human Anti-HIV-1 gp120 V3 Monoclonal Antibodies of the Same Gene Usage Induced by Vaccination and Chronic Infection

article

Structural analyses of antigen binding similarities and differences between rabbit and human anti-gp120 V3 mAbs

artículo científico publicado en 2012

Structural analysis of a novel rabbit monoclonal antibody R53 targeting an epitope in HIV-1 gp120 C4 region critical for receptor and co-receptor binding.

artículo científico publicado en 2015

Structural and Functional Studies of Aspergillus oryzae Cutinase: Enhanced Thermostability and Hydrolytic Activity of Synthetic Ester and Polyester Degradation

artículo científico publicado en 2009

Structural basis for tetraspanin functions as revealed by the cryo-EM structure of uroplakin complexes at 6-A resolution.

artículo científico publicado en 2006

Structural basis of urothelial permeability barrier function as revealed by Cryo-EM studies of the 16 nm uroplakin particle.

artículo científico publicado en 2003

Structural characterization of monoclonal antibodies targeting C-terminal Ser404 region of phosphorylated tau protein

artículo científico publicado en 2019

Structure of a Sliding Clamp on DNA

artículo científico publicado en 2008

Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp

artículo científico publicado en 2008

Structure of the Pentameric Ligand-Gated Ion Channel GLIC Bound with Anesthetic Ketamine

artículo científico publicado en 2012

Structure of the pentameric ligand-gated ion channel ELIC cocrystallized with its competitive antagonist acetylcholine

artículo científico publicado en 2012

Structure-based functional characterization of repressor of toxin (Rot), a central regulator of Staphylococcus aureus virulence.

artículo científico publicado en 2014

Structure-guided design and immunological characterization of immunogens presenting the HIV-1 gp120 V3 loop on a CTB scaffold.

artículo científico publicado en 2010

Structure/Function Studies Involving the V3 Region of the HIV-1 Envelope Delineate Multiple Factors That Affect Neutralization Sensitivity

artículo científico publicado en 2015

Tau Antibody Structure Reveals a Molecular Switch Defining a Pathological Conformation of the Tau Protein.

artículo científico publicado en 2018

Tau antibody chimerization alters its charge and binding, thereby reducing its cellular uptake and efficacy

artículo científico publicado en 2019

The V1V2 Region of HIV-1 gp120 Forms a Five-Stranded Beta Barrel

artículo científico publicado en 2015

The efficiency of bridging sheet recruitment determines HIV-1 R5 envelope sensitivity to soluble CD4 and macrophage tropism

artículo científico publicado en 2012

The structural features that distinguish PD-L2 from PD-L1 emerged in placental mammals

artículo científico publicado en 2019

The wide utility of rabbits as models of human diseases.

artículo científico publicado en 2018

Thermodynamic Signatures of the Antigen Binding Site of mAb 447–52D Targeting the Third Variable Region of HIV-1 gp120

artículo científico publicado en 2013

Uropathogenic E. coli adhesin-induced host cell receptor conformational changes: implications in transmembrane signaling transduction

artículo científico publicado en 2009

Uroplakin Ia is the urothelial receptor for uropathogenic<i>Escherichia coli</i>: evidence from in vitro FimH binding

artículo científico publicado en 2001

Uroplakins in urothelial biology, function, and disease

artículo científico publicado en 2009

VSV-Displayed HIV-1 Envelope Identifies Broadly Neutralizing Antibodies Class-Switched to IgG and IgA

artículo científico publicado en 2020

Vaccine focusing to cross-subtype HIV-1 gp120 variable loop epitopes.

artículo científico publicado en 2014

Vaccine-induced Human Antibodies Specific for the Third Variable Region of HIV-1 gp120 Impose Immune Pressure on Infecting Viruses

artículo científico publicado en 2014

Vaccine-induced V1V2-specific antibodies control and or protect against infection with HIV, SIV and SHIV

scientific article published on 01 July 2019

Viral Escape from Neutralizing Antibodies in Early Subtype A HIV-1 Infection Drives an Increase in Autologous Neutralization Breadth

artículo científico publicado en 2013

pH-dependent conformational switch activates the inhibitor of transcription elongation.

artículo científico publicado en 2006

Lista de obras de Xiang-Peng Kong

A new activity of anti-HIV and anti-tumor protein GAP31: DNA adenosine glycosidase--structural and modeling insight into its functions

A novel rabbit monoclonal antibody platform to dissect the diverse repertoire of antibody epitopes for HIV-1 Env immunogen design.

A site of vulnerability at V3 crown defined by HIV-1 bNAb M4008_N1

AMPA receptor tetramerization is mediated by Q/R editing

An HIV vaccine targeting the V2 region of Envelope induces a highly durable polyfunctional Fc-mediated antibody response in rhesus macaques

An adenosine deaminase (ADA) allele contains two newly identified deleterious mutations (Y97C and L106V) that interact to abolish enzyme activity ⬇️

An arsenite-inducible 19S regulatory particle-associated protein adapts proteasomes to proteotoxicity

Antigenic landscape of the HIV-1 envelope and new immunological concepts defined by HIV-1 broadly neutralizing antibodies.

Antiretroviral Imprints and Genomic Plasticity of HIV-1 <i>pol</i> in Non-clade B: Implications for Treatment

Atomic force microscopy of Mammalian urothelial surface

Author Correction: The wide utility of rabbits as models of human diseases

Biophysical dissection of the antigen-antibody interaction of the broadly reactive anti-V3 human mAb 447-52D.

Characteristics of the phagocytic cup induced by uropathogenic Escherichia coli.

Computational-guided determination of the functional role of 447-52D long CDRH3

Conserved structural elements in the V3 crown of HIV-1 gp120

Contrasting antibody responses to intrasubtype superinfection with CRF02_AG.

Cross-clade HIV-1 neutralizing antibodies induced with V3-scaffold protein immunogens following priming with gp120 DNA.

Crystal structure analysis of anti-V2 mAb 2158 suggests a conformational epitope involving an N-linked glycan

Crystal structure of human stem cell factor: implication for stem cell factor receptor dimerization and activation

Crystallization of Proliferating Cell Nuclear Antigen (PCNA) from Saccharomyces cerevisiae

Determinants of HIV-1 CD4-independent brain adaptation.

Differential V2-directed antibody responses in non-human primates infected with SHIVs or immunized with diverse HIV vaccines

Differential induction of anti-V3 crown antibodies with cradle- and ladle-binding modes in response to HIV-1 envelope vaccination.

Distinct Glycan Structures of Uroplakins Ia and Ib

Distinct Residues Contribute to Motility Repression and Autoregulation in the Proteus mirabilis Fimbria-Associated Transcriptional Regulator AtfJ.

Dual ligand/receptor interactions activate urothelial defenses against uropathogenic E. coli

Efficiency of bridging-sheet recruitment explains HIV-1 R5 envelope glycoprotein sensitivity to soluble CD4 and macrophage tropism

Elicitation of broadly reactive antibodies against glycan-modulated neutralizing V3 epitopes of HIV-1 by immune complex vaccines.

Emergence of SARS-CoV-2 through Recombination and Strong Purifying Selection

Emergence of SARS-CoV-2 through recombination and strong purifying selection

Epitope mapping of conformational V2-specific anti-HIV human monoclonal antibodies reveals an immunodominant site in V2.

Functional Antibody Response Against V1V2 and V3 of HIV gp120 in the VAX003 and VAX004 Vaccine Trials.

Functional Implications of the Binding Mode of a Human Conformation-Dependent V2 Monoclonal Antibody against HIV

Functional and Structural Characterization of Human V3-Specific Monoclonal Antibody 2424 with Neutralizing Activity against HIV-1 JRFL

Functional and immunochemical cross-reactivity of V2-specific monoclonal antibodies from HIV-1-infected individuals

Gp120 V5 Is Targeted by the First Wave of Sequential Neutralizing Antibodies in SHIVSF162P3N-Infected Rhesus Macaques.

High-resolution crystal structure of the Fv of quaternary neutralizing epitope mAb 2909 reveals atomic details of its antigen-binding site

Human Anti-V3 HIV-1 Monoclonal Antibodies Encoded by the VH5-51/VL Lambda Genes Define a Conserved Antigenic Structure

Identification of conserved amino acids in murine B7-1IgV domain critical for CTLA4/CD28:B7 interaction by site-directed mutagenesis: a novel structural model of the binding site.

Immune Correlates of Disease Progression in Linked HIV-1 Infection

Increased epitope complexity correlated with antibody affinity maturation and a novel binding mode revealed by structures of rabbit antibodies against the third variable loop (V3) of HIV-1 gp120.

Integrity of all four transmembrane domains of the tetraspanin uroplakin Ib is required for its exit from the ER.

Limonene reduces hyperalgesia induced by gp120 and cytokines by modulation of IL-1 β and protein expression in spinal cord of mice.

Localization of uroplakin Ia, the urothelial receptor for bacterial adhesin FimH, on the six inner domains of the 16 nm urothelial plaque particle.

Modulation of Antibody Responses to the V1V2 and V3 Regions of HIV-1 Envelope by Immune Complex Vaccines

Multimeric Epitope-Scaffold HIV Vaccines Target V1V2 and Differentially Tune Polyfunctional Antibody Responses

Organization of uroplakin subunits: transmembrane topology, pair formation and plaque composition

Priming with DNA expressing trimeric HIV V1V2 alters the immune hierarchy favoring the development of V2-specific antibodies in rhesus macaques

Rabbit Anti-HIV-1 Monoclonal Antibodies Raised by Immunization Can Mimic the Antigen-Binding Modes of Antibodies Derived from HIV-1-Infected Humans

Rationally Designed Immunogens Targeting HIV-1 gp120 V1V2 Induce Distinct Conformation-Specific Antibody Responses in Rabbits

Rationally Designed Vaccines Targeting the V2 Region of HIV-1 gp120 Induce a Focused, Cross-Clade-Reactive, Biologically Functional Antibody Response.

Rationally Targeted Mutations at the V1V2 Domain of the HIV-1 Envelope to Augment Virus Neutralization by Anti-V1V2 Monoclonal Antibodies.

Select gp120 V2 domain specific antibodies derived from HIV and SIV infection and vaccination inhibit gp120 binding to α4β7

Selective enrichment and fractionation of phosphopeptides from peptide mixtures by isoelectric focusing after methyl esterification

Sequential and compartmentalized action of Rabs, SNAREs, and MAL in the apical delivery of fusiform vesicles in urothelial umbrella cells

Sequential exposure to specific antibody escape mutations may program neutralization breadth during subtype A HIV-1 infection

Sequential trafficking of Env and Gag to HIV-1 T cell virological synapses revealed by live imaging

Signal peptide of HIV-1 envelope modulates glycosylation impacting exposure of V1V2 and other epitopes

Single genome analysis reveals genetic characteristics of Neuroadaptation across HIV-1 envelope.

Skin tattooing as a novel approach for DNA vaccine delivery.

Skin tattooing as an effective tool for delivering DNA and protein vaccine immunogens

Specificity of staphylococcal phage and SaPI DNA packaging as revealed by integrase and terminase mutations.

Structural Analysis of Human and Macaque mAbs 2909 and 2.5B: Implications for the Configuration of the Quaternary Neutralizing Epitope of HIV-1 gp120

Structural Basis of the Cross-Reactivity of Genetically Related Human Anti-HIV-1 mAbs: Implications for Design of V3-Based Immunogens

Structural Comparison of Human Anti-HIV-1 gp120 V3 Monoclonal Antibodies of the Same Gene Usage Induced by Vaccination and Chronic Infection

Structural analyses of antigen binding similarities and differences between rabbit and human anti-gp120 V3 mAbs

Structural analysis of a novel rabbit monoclonal antibody R53 targeting an epitope in HIV-1 gp120 C4 region critical for receptor and co-receptor binding.

Structural and Functional Studies of Aspergillus oryzae Cutinase: Enhanced Thermostability and Hydrolytic Activity of Synthetic Ester and Polyester Degradation

Structural basis for tetraspanin functions as revealed by the cryo-EM structure of uroplakin complexes at 6-A resolution.

Structural basis of urothelial permeability barrier function as revealed by Cryo-EM studies of the 16 nm uroplakin particle.

Structural characterization of monoclonal antibodies targeting C-terminal Ser404 region of phosphorylated tau protein

Structure of a Sliding Clamp on DNA

Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp

Structure of the Pentameric Ligand-Gated Ion Channel GLIC Bound with Anesthetic Ketamine

Structure of the pentameric ligand-gated ion channel ELIC cocrystallized with its competitive antagonist acetylcholine

Structure-based functional characterization of repressor of toxin (Rot), a central regulator of Staphylococcus aureus virulence.

Structure-guided design and immunological characterization of immunogens presenting the HIV-1 gp120 V3 loop on a CTB scaffold.

Structure/Function Studies Involving the V3 Region of the HIV-1 Envelope Delineate Multiple Factors That Affect Neutralization Sensitivity

Tau Antibody Structure Reveals a Molecular Switch Defining a Pathological Conformation of the Tau Protein.