Lista de obras - Christopher G Tate - Dominio Público Uruguay

A class of mild surfactants that keep integral membrane proteins water-soluble for functional studies and crystallization.

artículo científico publicado en 2011

A crystal clear solution for determining G-protein-coupled receptor structures ⬇️

artículo científico publicado el 10 de julio de 2012

A feast of membrane protein structures in Madrid. Workshop: Pumps, channels and transporters: structure and function

artículo científico publicado en 2001

A mutagenesis and screening strategy to generate optimally thermostabilized membrane proteins for structural studies

artículo científico publicado en 2016

Activation mechanism of the class D fungal GPCR dimer Ste2

artículo científico publicado en 2022

Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation

artículo científico publicado en 2011

Agonist-bound structures of G protein-coupled receptors

artículo científico publicado en 2012

An emerging consensus for the structure of EmrE.

artículo científico publicado en 2009

Baculovirus-mediated expression of neurotransmitter transporters.

artículo científico publicado en 1998

Biophysical Fragment Screening of the β 1 -Adrenergic Receptor: Identification of High Affinity Arylpiperazine Leads Using Structure-Based Drug Design

artículo científico publicado en 2013

Biophysical characterization of the cocaine binding pocket in the serotonin transporter using a fluorescent cocaine analogue as a molecular reporter

artículo científico publicado en 2000

Calnexin co-expression and the use of weaker promoters increase the expression of correctly assembled Shaker potassium channel in insect cells

artículo científico publicado en 2003

Calreticulin promotes folding/dimerization of human lipoprotein lipase expressed in insect cells (sf21).

artículo científico publicado en 2003

Co-evolving stability and conformational homogeneity of the human adenosine A2a receptor

artículo científico publicado en 2008

Comparison of seven different heterologous protein expression systems for the production of the serotonin transporter

artículo científico publicado en 2003

Comparison of three structures of the multidrug transporter EmrE.

artículo científico publicado en 2006

Conformational changes in the multidrug transporter EmrE associated with substrate binding

artículo científico publicado en 2003

Conformational thermostabilization of the beta1-adrenergic receptor in a detergent-resistant form

artículo científico publicado en 2008

Cryo-EM structure of the adenosine A2A receptor coupled to an engineered heterotrimeric G protein.

artículo científico publicado en 2018

Cryo-EM structure of the adenosine A2Areceptor coupled to an engineered heterotrimeric G protein

Cryo-EM structures of GPCRs coupled to Gs, Gi and Go

artículo científico publicado en 2019

Crystal Structures of a Stabilized β1-Adrenoceptor Bound to the Biased Agonists Bucindolol and Carvedilol ⬇️

artículo científico publicado en 2012

Crystal structure of rhodopsin in complex with a mini-G sheds light on the principles of G protein selectivity

artículo científico publicado en 2018

Development and crystallization of a minimal thermostabilised G protein-coupled receptor.

artículo científico publicado en 2009

Drug binding revealed by tandem mass spectrometry of a protein-micelle complex

artículo científico publicado en 2004

Dynamic behavior of the active and inactive states of the adenosine A(2A) receptor.

scientific article published on 17 March 2014

Editorial overview: New constructs and expression of proteins: Making things better

artículo científico publicado en 2014

Electron crystallography reveals plasticity within the drug binding site of the small multidrug transporter EmrE.

artículo científico publicado en 2008

Engineering G protein-coupled receptors to facilitate their structure determination.

scientific article published on 12 August 2009

Engineering an ultra-thermostable β(1)-adrenoceptor

artículo científico publicado en 2011

GPCR structure, function, drug discovery and crystallography: report from Academia-Industry International Conference (UK Royal Society) Chicheley Hall, 1-2 September 2014.

artículo científico publicado en 2015

Growth and excitement in membrane protein structural biology

scientific article published on 09 August 2010

Identification of a novel sugar-H+ symport protein, FucP, for transport of L-fucose into Escherichia coli

artículo científico publicado en 1994

Inability to N-glycosylate the human norepinephrine transporter reduces protein stability, surface trafficking, and transport activity but not ligand recognition

artículo científico publicado en 1996

Insight into partial agonism by observing multiple equilibria for ligand-bound and Gs-mimetic nanobody-bound β1-adrenergic receptor

artículo científico publicado en 2017

Interactions with other human UDP-glucuronosyltransferases attenuate the consequences of the Y485D mutation on the activity and substrate affinity of UGT1A6.

artículo científico publicado en 2007

Isolation and characterisation of transport-defective substrate-binding mutants of the tetracycline antiporter TetA(B).

artículo científico publicado en 2015

Les récepteurs couplés aux protéines G dans la lumière

scientific article published on 12 October 2012

Ligand occupancy in crystal structure of β1-adrenergic G protein-coupled receptor

artículo científico publicado en 2015

Mapping, cloning, expression, and sequencing of the rhaT gene, which encodes a novel L-rhamnose-H+ transport protein in Salmonella typhimurium and Escherichia coli

artículo científico publicado en 1992

Mass spectrometry of membrane transporters reveals subunit stoichiometry and interactions

artículo científico publicado en 2009

Membrane Protein Gymnastics

artículo científico publicado en 2010

Membrane topology of the L-rhamnose-H+ transport protein (RhaT) from enterobacteria.

artículo científico publicado en 1993

Mini-G proteins: Novel tools for studying GPCRs in their active conformation

artículo científico publicado en 2017

Molecular Determinants of CGS21680 Binding to the Human Adenosine A2A Receptor

artículo científico publicado en 2015

Molecular basis for high-affinity agonist binding in GPCRs

artículo científico publicado en 2019

Molecular basis of β-arrestin coupling to formoterol-bound β1-adrenoceptor

scientific article published on 17 June 2020

Molecular chaperones improve functional expression of the serotonin (5-hydroxytryptamine) transporter in insect cells.

artículo científico publicado en 1999

Molecular chaperones stimulate the functional expression of the cocaine-sensitive serotonin transporter

artículo científico publicado en 1999

Molecular signatures of G-protein-coupled receptors

artículo científico publicado en 2013

New insights into the structure and oligomeric state of the bacterial multidrug transporter EmrE: an unusual asymmetric homo-dimer

artículo científico publicado en 2004

Optimising the combination of thermostabilising mutations in the neurotensin receptor for structure determination

artículo científico publicado en 2013

Outrunning free radicals in room-temperature macromolecular crystallography

artículo científico publicado en 2012

Overcoming barriers to membrane protein structure determination

artículo científico publicado en 2011

Overexpression of mammalian integral membrane proteins for structural studies.

artículo científico publicado en 2001

Overexpression of membrane proteins in mammalian cells for structural studies ⬇️

artículo científico publicado el 11 de septiembre de 2012

Partitioning of the serotonin transporter into lipid microdomains modulates transport of serotonin

scientific journal article

Pharmacological Analysis and Structure Determination of 7-Methylcyanopindolol-Bound β1-Adrenergic Receptor.

artículo científico publicado en 2015

Pharmacology and structure of isolated conformations of the adenosine A₂A receptor define ligand efficacy

artículo científico publicado en 2013

Practical Considerations of Membrane Protein Instability during Purification and Crystallisation

scientific article published on 01 January 2010

Proton-linked L-rhamnose transport, and its comparison with L-fucose transport in Enterobacteriaceae

artículo científico publicado en 1993

Quality control in eukaryotic membrane protein overproduction

artículo científico publicado en 2014

Quasi-symmetry in the cryo-EM structure of EmrE provides the key to modeling its transmembrane domain

artículo científico publicado en 2006

Rapid Computational Prediction of Thermostabilizing Mutations for G Protein-Coupled Receptors.

artículo científico publicado en 2014

Rare coding variants of the adenosine A3 receptor are increased in autism: on the trail of the serotonin transporter regulome

artículo científico publicado en 2013

Structural dynamics and thermostabilization of neurotensin receptor 1

artículo científico publicado en 2015

Structure of a beta1-adrenergic G-protein-coupled receptor

artículo científico publicado en 2008

Structure of the Adenosine A2A Receptor in Complex with ZM241385 and the Xanthines XAC and Caffeine

artículo científico publicado en 2011

Structure of the agonist-bound neurotensin receptor

artículo científico publicado en 2012

Structure of the class D GPCR Ste2 dimer coupled to two G proteins

scientific article published on 02 December 2020

Structure tridimensionnelle du récepteur de l’adénosine A2Alié à son agoniste naturel l’adénosine

artículo científico publicado en 2011

Studies on human red-cell membrane glycophorin A and glycophorin B genes in glycophorin-deficient individuals

artículo científico publicado en 1989

Studies on the defect which causes absence of decay accelerating factor (DAF) from the peripheral blood cells of an individual with the Inab phenotype

artículo científico publicado en 1989

The 2.1 Å Resolution Structure of Cyanopindolol-Bound β1-Adrenoceptor Identifies an Intramembrane Na+ Ion that Stabilises the Ligand-Free Receptor

artículo científico publicado en 2014

The Emery-Dreifuss muscular dystrophy associated-protein emerin is phosphorylated on serine 49 by protein kinase A.

artículo científico publicado en 2006

The Escherichia coli multidrug transporter EmrE is a dimer in the detergent-solubilised state

artículo científico publicado en 2004

The effect of N-linked glycosylation on activity of the Na(+)- and Cl(-)-dependent serotonin transporter expressed using recombinant baculovirus in insect cells.

artículo científico publicado en 1994

The importance of interactions with helix 5 in determining the efficacy of β-adrenoceptor ligands

artículo científico

The pharmacological effects of the thermostabilising (m23) mutations and intra and extracellular (β36) deletions essential for crystallisation of the turkey β-adrenoceptor

artículo científico publicado en 2011

The projection structure of EmrE, a proton-linked multidrug transporter from Escherichia coli, at 7 A resolution

artículo científico publicado en 2001

The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor

artículo científico publicado en 2011

Thermostabilisation of an agonist-bound conformation of the human adenosine A(2A) receptor

artículo científico publicado en 2011

Thermostabilisation of the serotonin transporter in a cocaine-bound conformation

artículo científico publicado en 2013

Thermostabilization of the neurotensin receptor NTS1.

artículo científico publicado en 2009

Thermostabilization of the β1-adrenergic receptor correlates with increased entropy of the inactive state

artículo científico publicado en 2013

Three-dimensional structure of TspO by electron cryomicroscopy of helical crystals

artículo científico publicado en 2010

Three-dimensional structure of the bacterial multidrug transporter EmrE shows it is an asymmetric homodimer

artículo científico publicado en 2003

Topological analyses of the L-fucose-H+ symport protein, FucP, from Escherichia coli

artículo científico publicado en 1995

Transferability of thermostabilizing mutations between β-adrenergic receptors

scientific article published on 01 December 2009

Two distinct conformations of helix 6 observed in antagonist-bound structures of a 1-adrenergic receptor

artículo científico publicado en 2011

Lista de obras de Christopher G Tate

A class of mild surfactants that keep integral membrane proteins water-soluble for functional studies and crystallization.

A crystal clear solution for determining G-protein-coupled receptor structures ⬇️

A feast of membrane protein structures in Madrid. Workshop: Pumps, channels and transporters: structure and function

A mutagenesis and screening strategy to generate optimally thermostabilized membrane proteins for structural studies

Activation mechanism of the class D fungal GPCR dimer Ste2

Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation

Agonist-bound structures of G protein-coupled receptors

An emerging consensus for the structure of EmrE.

Baculovirus-mediated expression of neurotransmitter transporters.

Biophysical Fragment Screening of the β 1 -Adrenergic Receptor: Identification of High Affinity Arylpiperazine Leads Using Structure-Based Drug Design

Biophysical characterization of the cocaine binding pocket in the serotonin transporter using a fluorescent cocaine analogue as a molecular reporter

Calnexin co-expression and the use of weaker promoters increase the expression of correctly assembled Shaker potassium channel in insect cells

Calreticulin promotes folding/dimerization of human lipoprotein lipase expressed in insect cells (sf21).

Co-evolving stability and conformational homogeneity of the human adenosine A2a receptor

Comparison of seven different heterologous protein expression systems for the production of the serotonin transporter

Comparison of three structures of the multidrug transporter EmrE.

Conformational changes in the multidrug transporter EmrE associated with substrate binding

Conformational thermostabilization of the beta1-adrenergic receptor in a detergent-resistant form

Cryo-EM structure of the adenosine A2A receptor coupled to an engineered heterotrimeric G protein.

Cryo-EM structure of the adenosine A2Areceptor coupled to an engineered heterotrimeric G protein

Cryo-EM structures of GPCRs coupled to Gs, Gi and Go

Crystal Structures of a Stabilized β1-Adrenoceptor Bound to the Biased Agonists Bucindolol and Carvedilol ⬇️

Crystal structure of rhodopsin in complex with a mini-G sheds light on the principles of G protein selectivity

Development and crystallization of a minimal thermostabilised G protein-coupled receptor.

Drug binding revealed by tandem mass spectrometry of a protein-micelle complex

Dynamic behavior of the active and inactive states of the adenosine A(2A) receptor.

Editorial overview: New constructs and expression of proteins: Making things better

Electron crystallography reveals plasticity within the drug binding site of the small multidrug transporter EmrE.

Engineering G protein-coupled receptors to facilitate their structure determination.

Engineering an ultra-thermostable β(1)-adrenoceptor

GPCR structure, function, drug discovery and crystallography: report from Academia-Industry International Conference (UK Royal Society) Chicheley Hall, 1-2 September 2014.

Growth and excitement in membrane protein structural biology

Identification of a novel sugar-H+ symport protein, FucP, for transport of L-fucose into Escherichia coli

Inability to N-glycosylate the human norepinephrine transporter reduces protein stability, surface trafficking, and transport activity but not ligand recognition

Insight into partial agonism by observing multiple equilibria for ligand-bound and Gs-mimetic nanobody-bound β1-adrenergic receptor

Interactions with other human UDP-glucuronosyltransferases attenuate the consequences of the Y485D mutation on the activity and substrate affinity of UGT1A6.

Isolation and characterisation of transport-defective substrate-binding mutants of the tetracycline antiporter TetA(B).

Les récepteurs couplés aux protéines G dans la lumière

Ligand occupancy in crystal structure of β1-adrenergic G protein-coupled receptor

Mapping, cloning, expression, and sequencing of the rhaT gene, which encodes a novel L-rhamnose-H+ transport protein in Salmonella typhimurium and Escherichia coli

Mass spectrometry of membrane transporters reveals subunit stoichiometry and interactions

Membrane Protein Gymnastics

Membrane topology of the L-rhamnose-H+ transport protein (RhaT) from enterobacteria.

Mini-G proteins: Novel tools for studying GPCRs in their active conformation

Molecular Determinants of CGS21680 Binding to the Human Adenosine A2A Receptor

Molecular basis for high-affinity agonist binding in GPCRs

Molecular basis of β-arrestin coupling to formoterol-bound β1-adrenoceptor

Molecular chaperones improve functional expression of the serotonin (5-hydroxytryptamine) transporter in insect cells.

Molecular chaperones stimulate the functional expression of the cocaine-sensitive serotonin transporter

Molecular signatures of G-protein-coupled receptors

New insights into the structure and oligomeric state of the bacterial multidrug transporter EmrE: an unusual asymmetric homo-dimer

Optimising the combination of thermostabilising mutations in the neurotensin receptor for structure determination

Outrunning free radicals in room-temperature macromolecular crystallography

Overcoming barriers to membrane protein structure determination

Overexpression of mammalian integral membrane proteins for structural studies.

Overexpression of membrane proteins in mammalian cells for structural studies ⬇️

Partitioning of the serotonin transporter into lipid microdomains modulates transport of serotonin

Pharmacological Analysis and Structure Determination of 7-Methylcyanopindolol-Bound β1-Adrenergic Receptor.

Pharmacology and structure of isolated conformations of the adenosine A₂A receptor define ligand efficacy

Practical Considerations of Membrane Protein Instability during Purification and Crystallisation

Proton-linked L-rhamnose transport, and its comparison with L-fucose transport in Enterobacteriaceae

Quality control in eukaryotic membrane protein overproduction

Quasi-symmetry in the cryo-EM structure of EmrE provides the key to modeling its transmembrane domain

Rapid Computational Prediction of Thermostabilizing Mutations for G Protein-Coupled Receptors.

Rare coding variants of the adenosine A3 receptor are increased in autism: on the trail of the serotonin transporter regulome

Structural dynamics and thermostabilization of neurotensin receptor 1

Structure of a beta1-adrenergic G-protein-coupled receptor

Structure of the Adenosine A2A Receptor in Complex with ZM241385 and the Xanthines XAC and Caffeine

Structure of the agonist-bound neurotensin receptor

Structure of the class D GPCR Ste2 dimer coupled to two G proteins

Structure tridimensionnelle du récepteur de l’adénosine A2Alié à son agoniste naturel l’adénosine

Studies on human red-cell membrane glycophorin A and glycophorin B genes in glycophorin-deficient individuals

Studies on the defect which causes absence of decay accelerating factor (DAF) from the peripheral blood cells of an individual with the Inab phenotype

The 2.1 Å Resolution Structure of Cyanopindolol-Bound β1-Adrenoceptor Identifies an Intramembrane Na+ Ion that Stabilises the Ligand-Free Receptor

The Emery-Dreifuss muscular dystrophy associated-protein emerin is phosphorylated on serine 49 by protein kinase A.

The Escherichia coli multidrug transporter EmrE is a dimer in the detergent-solubilised state

The effect of N-linked glycosylation on activity of the Na(+)- and Cl(-)-dependent serotonin transporter expressed using recombinant baculovirus in insect cells.

The importance of interactions with helix 5 in determining the efficacy of β-adrenoceptor ligands

The pharmacological effects of the thermostabilising (m23) mutations and intra and extracellular (β36) deletions essential for crystallisation of the turkey β-adrenoceptor