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Lista de obras de William R Heath

A Liver Capsular Network of Monocyte-Derived Macrophages Restricts Hepatic Dissemination of Intraperitoneal Bacteria by Neutrophil Recruitment

artículo científico publicado en 2017

A Local Role for CD103+ Dendritic Cells in Atherosclerosis

article

A key role for ICAM-1 in generating effector cells mediating inflammatory responses

artículo científico publicado en 2001

A new IFN-like cytokine, limitin, modulates the immune response without influencing thymocyte development

artículo científico publicado en 2001

A role for plasmacytoid dendritic cells in the rapid IL-18-dependent activation of NK cells following HSV-1 infection

artículo científico publicado en 2007

A specific anti-Aire antibody reveals aire expression is restricted to medullary thymic epithelial cells and not expressed in periphery

artículo científico publicado en 2008

Aire regulates the transfer of antigen from mTECs to dendritic cells for induction of thymic tolerance

artículo científico publicado en 2011

Aire-deficient C57BL/6 mice mimicking the common human 13-base pair deletion mutation present with only a mild autoimmune phenotype

artículo científico publicado en 2009

Antibodies targeting Clec9A promote strong humoral immunity without adjuvant in mice and non-human primates

artículo científico publicado en 2015

Antibody responses initiated by Clec9A-bearing dendritic cells in normal and Batf3−/− mice

article

Antigen presentation by dendritic cells for B cell activation

scientific article published on 06 May 2019

Antigen-specific CD8+ T cell subset distribution in lymph nodes draining the site of herpes simplex virus infection

artículo científico publicado en 1997

Autoimmune regulator controls T cell help for pathogenetic autoantibody production in collagen-induced arthritis

artículo científico publicado en 2009

Blood-stage Plasmodium berghei infection generates a potent, specific CD8+ T-cell response despite residence largely in cells lacking MHC I processing machinery

artículo científico publicado en 2011

Blood-stage Plasmodium berghei infection leads to short-lived parasite-associated antigen presentation by dendritic cells

artículo científico publicado en 2010

Blood-stage Plasmodium infection induces CD8+ T lymphocytes to parasite-expressed antigens, largely regulated by CD8alpha+ dendritic cells

artículo científico publicado en 2008

Bone marrow-derived cells expand memory CD8+ T cells in response to viral infections of the lung and skin

artículo científico publicado en 2006

Breakdown in repression of IFN-γ mRNA leads to accumulation of self-reactive effector CD8+ T cells

artículo científico publicado en 2012

CD14 is not involved in the uptake of synthetic CpG oligonucleotides

artículo científico publicado en 2016

CD4(+) T-cell help amplifies innate signals for primary CD8(+) T-cell immunity

artículo científico publicado en 2016

CD4+ T cells can protect APC from CTL-mediated elimination

artículo científico publicado en 2006

CD8+ T cells from a novel T cell receptor transgenic mouse induce liver-stage immunity that can be boosted by blood-stage infection in rodent malaria

artículo científico publicado en 2014

CTL response compensation for the loss of an immunodominant class I-restricted HSV-1 determinant

article

Cell-type-specific recognition of allogeneic cells by alloreactive cytotoxic T cells: a consequence of peptide-dependent allorecognition.

artículo científico publicado en 1991

Cerebral Malaria in Mouse and Man

scholarly article by Nazanin Ghazanfari et al published 10 September 2018 in Frontiers in Immunology

Characterization of an immediate splenic precursor of CD8+ dendritic cells capable of inducing antiviral T cell responses

artículo científico publicado en 2009

Characterization of the ovalbumin-specific TCR transgenic line OT-I: MHC elements for positive and negative selection

article

Chemokine Receptor-Dependent Control of Skin Tissue-Resident Memory T Cell Formation

artículo científico publicado en 2017

Classical Type 1 Dendritic Cells Dominate Priming of Th1 Responses to Herpes Simplex Virus Type 1 Skin Infection

article

Cognate CD4(+) T cell licensing of dendritic cells in CD8(+) T cell immunity

artículo científico publicado en 2004

Constitutive, but not inflammatory, cross-presentation is disabled in the pancreas of young mice

artículo científico publicado en 2002

Coupling and cross-presentation

article

Cross-presentation in viral immunity and self-tolerance.

artículo científico publicado en 2001

Cross-presentation of viral and self antigens by skin-derived CD103+ dendritic cells

artículo científico publicado en 2009

Cross-presentation, dendritic cell subsets, and the generation of immunity to cellular antigens

artículo científico publicado en 2004

Cross-priming: its beginnings

artículo científico publicado en 2010

Cutting Edge: Conventional CD8α+ Dendritic Cells Are Preferentially Involved in CTL Priming After Footpad Infection with Herpes Simplex Virus-1 ⬇️

artículo científico publicado el 1 de mayo de 2003

Cutting edge: central memory T cells do not show accelerated proliferation or tissue infiltration in response to localized herpes simplex virus-1 infection

artículo científico publicado en 2006

Cutting edge: conventional CD8 alpha+ dendritic cells are generally involved in priming CTL immunity to viruses

artículo científico publicado en 2004

Cutting edge: local recall responses by memory T cells newly recruited to peripheral nonlymphoid tissues

artículo científico publicado en 2008

Cutting edge: priming of CD8 T cell immunity to herpes simplex virus type 1 requires cognate TLR3 expression in vivo

artículo científico publicado en 2010

Cutting edge: prolonged antigen presentation after herpes simplex virus-1 skin infection

artículo científico publicado en 2004

DEC-205 is a cell surface receptor for CpG oligonucleotides

artículo científico publicado en 2012

DEC-205 is a cell surface receptor for CpG oligonucleotides

article

Dangerous liaisons

artículo científico publicado en 2003

Defective TCR expression in transgenic mice constructed using cDNA-based α- and β-chain genes under the control of heterologous regulatory elements

article

Dendritic Cell-Induced Memory T Cell Activation in Nonlymphoid Tissues

artículo científico publicado en 2008

Dendritic cell preactivation impairs MHC class II presentation of vaccines and endogenous viral antigens

artículo científico publicado en 2007

Dendritic cell subsets in primary and secondary T cell responses at body surfaces

artículo científico publicado en 2009

Development of a Novel CD4+ TCR Transgenic Line That Reveals a Dominant Role for CD8+ Dendritic Cells and CD40 Signaling in the Generation of Helper and CTL Responses to Blood-Stage Malaria

artículo científico publicado en 2017

Different patterns of peripheral migration by memory CD4+ and CD8+ T cells

artículo científico publicado en 2011

Differential MHC class II synthesis and ubiquitination confers distinct antigen-presenting properties on conventional and plasmacytoid dendritic cells

article

Differential Migration of Epidermal and Dermal Dendritic Cells during Skin Infection

artículo científico publicado en 2009

Differential expression of pathogen-recognition molecules between dendritic cell subsets revealed by plasma membrane proteomic analysis

artículo científico publicado en 2010

Diminished secondary CTL response in draining lymph nodes on cutaneous challenge with herpes simplex virus.

artículo científico publicado en 2000

Display of Native Antigen on cDC1 That Have Spatial Access to Both T and B Cells Underlies Efficient Humoral Vaccination

artículo científico publicado en 2020

Distinct APC subtypes drive spatially segregated CD4+ and CD8+ T-cell effector activity during skin infection with HSV-1

artículo científico publicado en 2014

Distinct migrating and nonmigrating dendritic cell populations are involved in MHC class I-restricted antigen presentation after lung infection with virus

artículo científico publicado en 2004

Distinct resident and recirculating memory T cell subsets in non-lymphoid tissues

artículo científico publicado en 2013

Education and promiscuity

scientific article published in Nature

Effective Priming of Herpes Simplex Virus-Specific CD8+ T Cells In Vivo Does Not Require Infected Dendritic Cells ⬇️

artículo científico publicado en 2017

Epidermal viral immunity induced by CD8alpha+ dendritic cells but not by Langerhans cells

artículo científico publicado en 2003

Equivalent stimulation of naive and memory CD8 T cells by DNA vaccination: a dendritic cell-dependent process

artículo científico publicado en 2009

Erratum to: Single cell analysis of CD4+ T cell differentiation reveals three major cell states and progressive acceleration of proliferation

artículo científico publicado en 2016

Expression of two T cell receptor α chains on the surface of normal murine T cells

article

Gamma interferon-independent effects of interleukin-12 on immunity to Salmonella enterica serovar Typhimurium

artículo científico publicado en 2007

Generic construction of single component particles that elicit humoural and cellular immune responses without the need for adjuvants

article

Glycolipid-peptide vaccination induces liver-resident memory CD8+ T cells that protect against rodent malaria

artículo científico publicado en 2020

Granzyme B expression by CD8+ T cells is required for the development of experimental cerebral malaria

artículo científico publicado en 2011

Hair follicles: gatekeepers to the epidermis ⬇️

artículo científico publicado el 19 de julio de 2012

Help for cytotoxic-T-cell responses is mediated by CD40 signalling

artículo científico publicado en 1998

Helper T cells, dendritic cells and CTL Immunity

artículo científico publicado en 2004

Helper requirements for generation of effector CTL to islet beta cell antigens

artículo científico publicado en 2004

Hemozoin-mediated inflammasome activation limits long-lived anti-malarial immunity

artículo científico publicado en 2021

Herpes simplex virus-specific CD8+ T cells can clear established lytic infections from skin and nerves and can partially limit the early spread of virus after cutaneous inoculation

artículo científico publicado en 2004

IFN Regulatory Factor 3 Balances Th1 and T Follicular Helper Immunity during Nonlethal Blood-Stage Plasmodium Infection

artículo científico publicado en 2018

IP-10-mediated T cell homing promotes cerebral inflammation over splenic immunity to malaria infection

artículo científico publicado en 2009

Identification of a MHC I-restricted epitope of DsRed in C57BL/6 mice

article

Immunity or tolerance? That is the question for dendritic cells

article

Induction of T-cell-mediated skin disease specific for antigen transgenically expressed in keratinocytes

article

Induction of tumor cell apoptosis in vivo increases tumor antigen cross-presentation, cross-priming rather than cross-tolerizing host tumor-specific CD8 T cells

artículo científico publicado en 2003

Infection Programs Sustained Lymphoid Stromal Cell Responses and Shapes Lymph Node Remodeling upon Secondary Challenge

artículo científico publicado en 2017

Inhibition of naïve class I-restricted T cells by altered peptide ligands

scientific article published on 01 August 1999

Intrahepatic activation of naive CD4+ T cells by liver-resident phagocytic cells

artículo científico publicado en 2014

Kidney protection against autoreactive CD8(+) T cells distinct from immunoprivilege and sequestration.

artículo científico publicado en 2001

Krüppel-ling of IRF4-Dependent DCs into Two Functionally Distinct DC Subsets

artículo científico publicado en 2015

Latent infection with herpes simplex virus is associated with ongoing CD8+ T-cell stimulation by parenchymal cells within sensory ganglia

artículo científico publicado en 2005

Life cycle, migration and antigen presenting functions of spleen and lymph node dendritic cells: limitations of the Langerhans cells paradigm

artículo científico publicado en 2005

Liver-Resident Memory CD8+ T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection

artículo científico publicado en 2016

Liver-Resident Memory CD8+ T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection

scientific article published on 01 October 2019

Local proliferation maintains a stable pool of tissue-resident memory T cells after antiviral recall responses

artículo científico publicado en 2018

Long-lived epithelial immunity by tissue-resident memory T (TRM) cells in the absence of persisting local antigen presentation.

artículo científico publicado en 2012

Loss of Antiviral Cytotoxic T-Lymphocyte Activity During High-Level Antigen Stimulation

article

Maintenance of T cell function in the face of chronic antigen stimulation and repeated reactivation for a latent virus infection

artículo científico publicado en 2012

Memory T cell subsets, migration patterns, and tissue residence

artículo científico publicado en 2012

Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virus

artículo científico publicado en 2009

Migratory CD11b+ conventional dendritic cells induce T follicular helper cell-dependent antibody responses.

artículo científico publicado en 2017

Migratory Dendritic Cells Transfer Antigen to a Lymph Node-Resident Dendritic Cell Population for Efficient CTL Priming

article

Minimal activation of memory CD8+ T cell by tissue-derived dendritic cells favors the stimulation of naive CD8+ T cells

article

Most lymphoid organ dendritic cell types are phenotypically and functionally immature

artículo científico publicado en 2003

Multiple dendritic cell populations activate CD4+ T cells after viral stimulation

artículo científico publicado en 2008

NLRC4 inflammasomes in dendritic cells regulate noncognate effector function by memory CD8⁺ T cells

artículo científico publicado en 2012

Negative selection of semimature CD4(+)8(-)HSA+ thymocytes requires the BH3-only protein Bim but is independent of death receptor signaling

artículo científico publicado en 2004

Neutrophils are dispensable in the modulation of T cell immunity against cutaneous HSV-1 infection

scientific article published on 23 January 2017

No driving without a license

article

Normal proportion and expression of maturation markers in migratory dendritic cells in the absence of germs or Toll-like receptor signaling

article

Optimization of TCR transgenic T cells for in vivo tracking of immune responses

artículo científico publicado en 2007

Outside looking in: the inner workings of the cross-presentation pathway within dendritic cells

artículo científico publicado en 2007

Peptide antagonists that promote positive selection are inefficient at T cell activation and thymocyte deletion

article

Peptide-dependent recognition of H-2Kb by alloreactive cytotoxic T lymphocytes

artículo científico publicado en 1989

Peripheral deletion of autoreactive CD8 T cells by cross presentation of self-antigen occurs by a Bcl-2-inhibitable pathway mediated by Bim

artículo científico publicado en 2002

Peripheral deletion of autoreactive CD8+ T cells in transgenic mice expressing H-2Kb in the liver

article

Peripheral tissue surveillance and residency by memory T cells

artículo científico

Persistence of skin-resident memory T cells within an epidermal niche

artículo científico publicado en 2014

Progression of armed CTL from draining lymph node to spleen shortly after localized infection with herpes simplex virus 1.

artículo científico publicado en 2002

Protective immunity to liver-stage malaria

artículo científico publicado en 2016

Proteomic and metabolomic analyses of mitochondrial complex I-deficient mouse model generated by spontaneous B2 short interspersed nuclear element (SINE) insertion into NADH dehydrogenase (ubiquinone) Fe-S protein 4 (Ndufs4) gene

scientific journal article

Putative IKDCs are functionally and developmentally similar to natural killer cells, but not to dendritic cells

artículo científico publicado en 2007

Rapid recruitment and activation of CD8+ T cells after herpes simplex virus type 1 skin infection

artículo científico publicado en 2010

Reactive murine lymph nodes uniquely permit parenchymal access for T cells that enter via the afferent lymphatics

artículo científico publicado en 2012

Resident Memory T Cells and Their Role within the Liver

artículo científico publicado en 2020

Resident memory CD8+ T cells in the upper respiratory tract prevent pulmonary influenza virus infection.

artículo científico publicado en 2017

SOCS-1 regulates IL-15-driven homeostatic proliferation of antigen-naive CD8 T cells, limiting their autoimmune potential

artículo científico publicado en 2005

SOCS1: a potent and multifaceted regulator of cytokines and cell-mediated inflammation.

artículo científico publicado en 2006

Selected Toll-like receptor ligands and viruses promote helper-independent cytotoxic T cell priming by upregulating CD40L on dendritic cells

artículo científico publicado en 2009

Selective suicide of cross-presenting CD8+ dendritic cells by cytochrome c injection shows functional heterogeneity within this subset

artículo científico publicado en 2008

Signalling through CD30 protects against autoimmune diabetes mediated by CD8 T cells

artículo científico publicado en 1999

Single-cell RNA-seq and computational analysis using temporal mixture modelling resolves Th1/Tfh fate bifurcation in malaria

artículo científico publicado en 2017

Skin CD4(+) memory T cells exhibit combined cluster-mediated retention and equilibration with the circulation

artículo científico publicado en 2016

Skin-derived dendritic cells can mediate deletional tolerance of class I-restricted self-reactive T cells

artículo científico publicado en 2007

Spatiotemporally Distinct Interactions with Dendritic Cell Subsets Facilitates CD4+ and CD8+ T Cell Activation to Localized Viral Infection

artículo científico publicado en 2015

Species-restricted interactions between CD8 and the alpha 3 domain of class I influence the magnitude of the xenogeneic response

artículo científico publicado en 1989

Systemic activation of dendritic cells by Toll-like receptor ligands or malaria infection impairs cross-presentation and antiviral immunity

artículo científico publicado en 2006

T Cell Help Amplifies Innate Signals in CD8(+) DCs for Optimal CD8(+) T Cell Priming.

artículo científico publicado en 2016

Targeting Antigen to Clec9A Primes Follicular Th Cell Memory Responses Capable of Robust Recall

artículo científico publicado en 2015

Targeting Dendritic Cells in vivo for Cancer Therapy

artículo científico publicado en 2012

Targeting antigen to mouse dendritic cells via Clec9A induces potent CD4 T cell responses biased toward a follicular helper phenotype

artículo científico publicado en 2011

The C-Type Lectin Clec12A Present on Mouse and Human Dendritic Cells Can Serve as a Target for Antigen Delivery and Enhancement of Antibody Responses

article

The CD8+ dendritic cell subset

artículo científico publicado en 2010

The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation

artículo científico publicado en 2020

The clonal selection theory: 50 years since the revolution

artículo científico publicado en 2007

The cryo-EM structure of the endocytic receptor DEC-205

scientific article published on 30 November 2020

The dendritic cell subtype-restricted C-type lectin Clec9A is a target for vaccine enhancement

artículo científico publicado en 2008

The developmental pathway for CD103(+)CD8+ tissue-resident memory T cells of skin.

artículo científico publicado en 2013

The dominant role of CD8+ dendritic cells in cross-presentation is not dictated by antigen capture

artículo científico publicado en 2006

The early expression of glycoprotein B from herpes simplex virus can be detected by antigen-specific CD8+ T cells

artículo científico publicado en 2003

The molecular signature of CD8+ T cells undergoing deletional tolerance

artículo científico publicado en 2009

The role of dendritic cell subsets in selection between tolerance and immunity

artículo científico publicado en 2002

The skin-resident and migratory immune system in steady state and memory: innate lymphocytes, dendritic cells and T cells

artículo científico publicado en 2013

The threshold for autoimmune T cell killing is influenced by B7-1

article

Tissue destruction caused by cytotoxic T lymphocytes induces deletional tolerance

scholarly article

Too dangerous to ignore: self-tolerance and the control of ignorant autoreactive T cells

artículo científico publicado en 2008

Transfer of antigen between migrating and lymph node-resident DCs in peripheral T-cell tolerance and immunity

artículo científico publicado en 2004

Unresponsiveness to inhaled antigen is governed by conventional dendritic cells and overridden during infection by monocytes

artículo científico publicado en 2020

Up-regulation of LFA-1 allows liver-resident memory T cells to patrol and remain in the hepatic sinusoids.

artículo científico publicado en 2017

Virus infection expands a biased subset of T cells that bind tetrameric class I peptide complexes.

artículo científico publicado en 2003

Without peripheral interference, thymic deletion is mediated in a cohort of double-positive cells without classical activation

artículo científico publicado en 2003

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