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Lista de obras de Qin Yan

5-Fluorouracil efficacy requires anti-tumor immunity triggered by cancer-cell-intrinsic STING

artículo científico publicado en 2021

A Role for the TFIIH XPB DNA Helicase in Promoter Escape by RNA Polymerase II

artículo científico publicado en 1999

Acquired Resistance to HER2-Targeted Therapies Creates Vulnerability to ATP Synthase Inhibition

artículo científico publicado en 2019

An easy and efficient inducible CRISPR/Cas9 platform with improved specificity for multiple gene targeting

scientific article published on 25 July 2016

Annotation and cluster analysis of long noncoding RNA linked to male sex and estrogen in cancers

artículo científico publicado en 2020

Both BC-box motifs of adenovirus protein E4orf6 are required to efficiently assemble an E3 ligase complex that degrades p53.

artículo científico publicado en 2004

Cancer progression is mediated by proline catabolism in non-small cell lung cancer

artículo científico publicado en 2020

Cell Division Cycle 42 plays a Cell type-Specific role in Lung Tumorigenesis

artículo científico publicado en 2017

Coordinated repression of cell cycle genes by KDM5A and E2F4 during differentiation

artículo científico publicado en 2012

Correction to: Long noncoding RNA LINC00336 inhibits ferroptosis in lung cancer by functioning as a competing endogenous RNA

artículo científico publicado en 2020

Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex

artículo científico publicado en 2001

Dual roles for transcription factor IIF in promoter escape by RNA polymerase II.

artículo científico publicado en 1999

Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer.

artículo científico publicado en 2011

Epigenetic mechanisms in commonly occurring cancers.

artículo científico publicado en 2012

GIAT4RA functions as a tumor suppressor in non-small cell lung cancer by counteracting Uchl3-mediated deubiquitination of LSH

scientific article published on 15 August 2019

High-Throughput Deep Sequencing for Mapping Mammalian DNA Methylation

artículo científico publicado en 2016

High-throughput screening to identify inhibitors of lysine demethylases

artículo científico publicado en 2015

Histone demethylase RBP2 is critical for breast cancer progression and metastasis.

artículo científico publicado en 2014

Histone demethylase RBP2 promotes lung tumorigenesis and cancer metastasis.

artículo científico publicado en 2013

Histone demethylase jumonji AT-rich interactive domain 1B (JARID1B) controls mammary gland development by regulating key developmental and lineage specification genes

scientific journal article

Histone demethylases set the stage for cancer metastasis.

artículo científico

Hypoxia-inducible factor linked to differential kidney cancer risk seen with type 2A and type 2B VHL mutations.

artículo científico publicado en 2007

Identification and Validation of a Novel Biologics Target in Triple Negative Breast Cancer

scientific article published on 17 October 2019

Identification of Elongin C and Skp1 sequences that determine Cullin selection

artículo científico publicado en 2004

Identification of small molecule inhibitors of Jumonji AT-rich interactive domain 1B (JARID1B) histone demethylase by a sensitive high throughput screen.

artículo científico publicado en 2013

Illumina Sequencing of Bisulfite-Converted DNA Libraries

artículo científico publicado en 2016

Insights into the Action of Inhibitor Enantiomers against Histone Lysine Demethylase 5A.

artículo científico publicado en 2018

KDM5 histone demethylases repress immune response via suppression of STING

artículo científico publicado en 2018

KDM5 lysine demethylases are involved in maintenance of 3'UTR length.

artículo científico publicado en 2016

KDM5B is essential for the hyper-activation of PI3K/AKT signaling in prostate tumorigenesis

scientific article published on 31 August 2020

KDM5B promotes immune evasion by recruiting SETDB1 to silence retroelements

artículo científico publicado en 2021

Long noncoding RNA LINC00336 inhibits ferroptosis in lung cancer by functioning as a competing endogenous RNA

scientific article published on 20 February 2019

Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1

artículo científico publicado en 2011

MAL2 mediates the formation of stable HER2 signaling complexes within lipid raft-rich membrane protrusions in breast cancer cells

artículo científico publicado en 2021

Muf1, a novel Elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase

artículo científico publicado en 2001

Multi-Omics Investigation of Innate Navitoclax Resistance in Triple-Negative Breast Cancer Cells

scientific article published on 08 September 2020

Multiple tumor suppressors regulate a HIF-dependent negative feedback loop via ISGF3 in human clear cell renal cancer

artículo científico publicado en 2018

PBRM1 acts as a p53 lysine-acetylation reader to suppress renal tumor growth

scientific article published on 20 December 2019

Potent BRD4 inhibitor suppresses cancer cell-macrophage interaction

scientific article published on 14 April 2020

Significance of glioma-associated oncogene homolog 1 (GLI1) expression in claudin-low breast cancer and crosstalk with the nuclear factor kappa-light-chain-enhancer of activated B cells (NFκB) pathway

artículo científico publicado en 2014

Specific chromatin landscapes and transcription factors couple breast cancer subtype with metastatic relapse to lung or brain

scientific article published on 06 March 2020

Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds

artículo científico publicado en 2016

The KDM5 family is required for activation of pro-proliferative cell cycle genes during adipocyte differentiation

artículo científico publicado en 2016

The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2

artículo científico publicado en 1999

The multiplexed CRISPR targeting platforms

scientific article published on 04 February 2018

The retinoblastoma binding protein RBP2 is an H3K4 demethylase

artículo científico

The von Hippel-Lindau tumor suppressor protein regulates gene expression and tumor growth through histone demethylase JARID1C.

artículo científico publicado en 2011

Transcription Factors TFIIF, ELL, and Elongin Negatively Regulate SII-induced Nascent Transcript Cleavage by Non-arrested RNA Polymerase II Elongation Intermediates

artículo científico publicado en 2001

pVHL acts as an adaptor to promote the inhibitory phosphorylation of the NF-kappaB agonist Card9 by CK2

artículo científico publicado en 2007