Lista de obras - Alexey Kotlyarov - Dominio Público Uruguay

A requirement of MAPKAPK2 in the uropod localization of PTEN during FMLP-induced neutrophil chemotaxis

artículo científico publicado en 2004

Analysis of properties of small heat shock protein Hsp25 in MAPK-activated protein kinase 2 (MK2)-deficient cells: MK2-dependent insolubilization of Hsp25 oligomers correlates with susceptibility to stress

artículo científico publicado en 2006

Characterization of the atypical MAPK ERK4 and its activation of the MAPK-activated protein kinase MK5

scientific journal article

Comparative Analysis of Two Gene-Targeting Approaches Challenges the Tumor-Suppressive Role of the Protein Kinase MK5/PRAK

artículo científico publicado en 2015

Constitutive activation of mitogen-activated protein kinase-activated protein kinase 2 by mutation of phosphorylation sites and an A-helix motif

scientific journal article

Distinct cellular functions of MK2.

artículo científico publicado en 2002

Distinct functions of the mitogen-activated protein kinase-activated protein (MAPKAP) kinases MK2 and MK3: MK2 mediates lipopolysaccharide-induced signal transducers and activators of transcription 3 (STAT3) activation by preventing negative regulat

artículo científico publicado en 2011

Elimination of protein kinase MK5/PRAK activity by targeted homologous recombination

artículo científico publicado en 2003

Endoplasmic reticulum-associated ubiquitin-conjugating enzyme Ube2j1 is a novel substrate of MK2 (MAPKAP kinase-2) involved in MK2-mediated TNFα production

scientific journal article

Fluorescence-based quantitative scratch wound healing assay demonstrating the role of MAPKAPK-2/3 in fibroblast migration

GTPase domain driven dimerization of SEPT7 is dispensable for the critical role of septins in fibroblast cytokinesis

artículo científico publicado en 2016

Gene deletion of MK2 inhibits TNF-alpha and IL-6 and protects against cerulein-induced pancreatitis

artículo científico publicado en 2006

Genetic deletion of SEPT7 reveals a cell type-specific role of septins in microtubule destabilization for the completion of cytokinesis

artículo científico publicado en 2014

Genetic dissection of the cellular pathways and signaling mechanisms in modeled tumor necrosis factor-induced Crohn's-like inflammatory bowel disease

artículo científico publicado en 2002

Germ Line Deletion Reveals a Nonessential Role of Atypical Mitogen-Activated Protein Kinase 6/Extracellular Signal-Regulated Kinase 3

scientific article published on 01 March 2019

HDM2 phosphorylation by MAPKAP kinase 2.

artículo científico publicado en 2005

Is MK2 (mitogen-activated protein kinase-activated protein kinase 2) the key for understanding post-transcriptional regulation of gene expression?

artículo científico publicado en 2002

Leptomycin B-sensitive nuclear export of MAPKAP kinase 2 is regulated by phosphorylation

artículo científico publicado en 1998

MAP-kinase-activated protein kinase 2 expression and activity is induced after neuronal depolarization.

artículo científico publicado en 2008

MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis

scientific journal article

MAPKAP kinase 2 phosphorylates serum response factor in vitro and in vivo

scientific journal article

MAPKAP kinase 2-deficiency prevents neurons from cell death by reducing neuroinflammation – relevance in a mouse model of Parkinson’s disease

article

MAPKAP kinase MK2 maintains self-renewal capacity of haematopoietic stem cells

artículo científico publicado en 2009

MAPKAP kinases MK2 and MK3 in inflammation: complex regulation of TNF biosynthesis via expression and phosphorylation of tristetraprolin

artículo científico publicado en 2010

MK2 and MK3--a pair of isoenzymes?

artículo científico publicado en 2008

MK2 targets AU-rich elements and regulates biosynthesis of tumor necrosis factor and interleukin-6 independently at different post-transcriptional levels

scientific journal article

Mitogen-activated protein kinase-activated protein kinase 2 regulates tumor necrosis factor mRNA stability and translation mainly by altering tristetraprolin expression, stability, and binding to adenine/uridine-rich element

artículo científico publicado en 2006

Mitogen-activated protein kinase-activated protein kinase 2-deficient mice show increased susceptibility to Listeria monocytogenes infection

artículo científico publicado en 2002

Molecular mechanisms of phosphorylation-regulated TTP (tristetraprolin) action and screening for further TTP-interacting proteins

artículo científico publicado en 2010

Mouse Hsp25, a small heat shock protein

article

Mouse Hsp25, a small shock protein. The role of its C-terminal extension in oligomerization and chaperone action

artículo científico publicado en 2000

Protein Kinases as Substrates for SAPKs

Regulation of Hsp27 oligomerization, chaperone function, and protective activity against oxidative stress/tumor necrosis factor alpha by phosphorylation

artículo científico publicado en 1999

SB202190-induced cell type-specific vacuole formation and defective autophagy do not depend on p38 MAP kinase inhibition

artículo científico publicado en 2011

Scaffolding by ERK3 regulates MK5 in development

scientific journal article

Small-molecule protein and lipid kinase inhibitors in inflammation and specific models for their evaluation

artículo científico publicado en 2012

Stress induced gene expression: a direct role for MAPKAP kinases in transcriptional activation of immediate early genes

artículo científico publicado en 2010

Stress-dependent phosphorylation of myocardin-related transcription factor A (MRTF-A) by the p38(MAPK)/MK2 axis

artículo científico publicado en 2016

Stress-induced stimulation of early growth response gene-1 by p38/stress-activated protein kinase 2 is mediated by a cAMP-responsive promoter element in a MAPKAP kinase 2-independent manner

scientific journal article

Targeting innate immunity protein kinase signalling in inflammation

artículo científico publicado en 2009

The MAPK-Activated Kinase MK2 Attenuates Dendritic Cell-Mediated Th1 Differentiation and Autoimmune Encephalomyelitis

artículo científico publicado en 2015

The extracellular signal-regulated kinase 3 (mitogen-activated protein kinase 6 [MAPK6])-MAPK-activated protein kinase 5 signaling complex regulates septin function and dendrite morphology

artículo científico publicado en 2012

The mitogen-activated protein kinase (MAPK)-activated protein kinases MK2 and MK3 cooperate in stimulation of tumor necrosis factor biosynthesis and stabilization of p38 MAPK.

artículo científico publicado en 2006

The p38/MK2-driven exchange between tristetraprolin and HuR regulates AU-rich element-dependent translation

artículo científico publicado en 2012

The problem of pyridinyl imidazole class inhibitors of MAPK14/p38α and MAPK11/p38β in autophagy research

artículo científico publicado en 2015

p38 MAP kinase and MAPKAP kinases MK2/3 cooperatively phosphorylate epithelial keratins

artículo científico publicado en 2010

p38MAPK/MK2-dependent phosphorylation controls cytotoxic RIPK1 signalling in inflammation and infection

artículo científico publicado en 2017

p38MAPK/MK2-mediated phosphorylation of RBM7 regulates the human nuclear exosome targeting complex

artículo científico publicado en 2014

Lista de obras de Alexey Kotlyarov

A requirement of MAPKAPK2 in the uropod localization of PTEN during FMLP-induced neutrophil chemotaxis

Analysis of properties of small heat shock protein Hsp25 in MAPK-activated protein kinase 2 (MK2)-deficient cells: MK2-dependent insolubilization of Hsp25 oligomers correlates with susceptibility to stress

Characterization of the atypical MAPK ERK4 and its activation of the MAPK-activated protein kinase MK5

Comparative Analysis of Two Gene-Targeting Approaches Challenges the Tumor-Suppressive Role of the Protein Kinase MK5/PRAK

Constitutive activation of mitogen-activated protein kinase-activated protein kinase 2 by mutation of phosphorylation sites and an A-helix motif

Distinct cellular functions of MK2.

Distinct functions of the mitogen-activated protein kinase-activated protein (MAPKAP) kinases MK2 and MK3: MK2 mediates lipopolysaccharide-induced signal transducers and activators of transcription 3 (STAT3) activation by preventing negative regulat

Elimination of protein kinase MK5/PRAK activity by targeted homologous recombination

Endoplasmic reticulum-associated ubiquitin-conjugating enzyme Ube2j1 is a novel substrate of MK2 (MAPKAP kinase-2) involved in MK2-mediated TNFα production

Fluorescence-based quantitative scratch wound healing assay demonstrating the role of MAPKAPK-2/3 in fibroblast migration

GTPase domain driven dimerization of SEPT7 is dispensable for the critical role of septins in fibroblast cytokinesis

Gene deletion of MK2 inhibits TNF-alpha and IL-6 and protects against cerulein-induced pancreatitis

Genetic deletion of SEPT7 reveals a cell type-specific role of septins in microtubule destabilization for the completion of cytokinesis

Genetic dissection of the cellular pathways and signaling mechanisms in modeled tumor necrosis factor-induced Crohn's-like inflammatory bowel disease

Germ Line Deletion Reveals a Nonessential Role of Atypical Mitogen-Activated Protein Kinase 6/Extracellular Signal-Regulated Kinase 3

HDM2 phosphorylation by MAPKAP kinase 2.

Is MK2 (mitogen-activated protein kinase-activated protein kinase 2) the key for understanding post-transcriptional regulation of gene expression?

Leptomycin B-sensitive nuclear export of MAPKAP kinase 2 is regulated by phosphorylation

MAP-kinase-activated protein kinase 2 expression and activity is induced after neuronal depolarization.

MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis

MAPKAP kinase 2 phosphorylates serum response factor in vitro and in vivo

MAPKAP kinase 2-deficiency prevents neurons from cell death by reducing neuroinflammation – relevance in a mouse model of Parkinson’s disease

MAPKAP kinase MK2 maintains self-renewal capacity of haematopoietic stem cells

MAPKAP kinases MK2 and MK3 in inflammation: complex regulation of TNF biosynthesis via expression and phosphorylation of tristetraprolin

MK2 and MK3--a pair of isoenzymes?

MK2 targets AU-rich elements and regulates biosynthesis of tumor necrosis factor and interleukin-6 independently at different post-transcriptional levels

Mitogen-activated protein kinase-activated protein kinase 2 regulates tumor necrosis factor mRNA stability and translation mainly by altering tristetraprolin expression, stability, and binding to adenine/uridine-rich element

Mitogen-activated protein kinase-activated protein kinase 2-deficient mice show increased susceptibility to Listeria monocytogenes infection

Molecular mechanisms of phosphorylation-regulated TTP (tristetraprolin) action and screening for further TTP-interacting proteins

Mouse Hsp25, a small heat shock protein

Mouse Hsp25, a small shock protein. The role of its C-terminal extension in oligomerization and chaperone action

Protein Kinases as Substrates for SAPKs

Regulation of Hsp27 oligomerization, chaperone function, and protective activity against oxidative stress/tumor necrosis factor alpha by phosphorylation

SB202190-induced cell type-specific vacuole formation and defective autophagy do not depend on p38 MAP kinase inhibition

Scaffolding by ERK3 regulates MK5 in development

Small-molecule protein and lipid kinase inhibitors in inflammation and specific models for their evaluation

Stress induced gene expression: a direct role for MAPKAP kinases in transcriptional activation of immediate early genes

Stress-dependent phosphorylation of myocardin-related transcription factor A (MRTF-A) by the p38(MAPK)/MK2 axis

Stress-induced stimulation of early growth response gene-1 by p38/stress-activated protein kinase 2 is mediated by a cAMP-responsive promoter element in a MAPKAP kinase 2-independent manner

Targeting innate immunity protein kinase signalling in inflammation

The MAPK-Activated Kinase MK2 Attenuates Dendritic Cell-Mediated Th1 Differentiation and Autoimmune Encephalomyelitis

The extracellular signal-regulated kinase 3 (mitogen-activated protein kinase 6 [MAPK6])-MAPK-activated protein kinase 5 signaling complex regulates septin function and dendrite morphology

The mitogen-activated protein kinase (MAPK)-activated protein kinases MK2 and MK3 cooperate in stimulation of tumor necrosis factor biosynthesis and stabilization of p38 MAPK.

The p38/MK2-driven exchange between tristetraprolin and HuR regulates AU-rich element-dependent translation

The problem of pyridinyl imidazole class inhibitors of MAPK14/p38α and MAPK11/p38β in autophagy research

p38 MAP kinase and MAPKAP kinases MK2/3 cooperatively phosphorylate epithelial keratins

p38MAPK/MK2-dependent phosphorylation controls cytotoxic RIPK1 signalling in inflammation and infection

p38MAPK/MK2-mediated phosphorylation of RBM7 regulates the human nuclear exosome targeting complex