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Lista de obras de Kevin M. Prise

1st L. H. Gray Workshop. Measurement of radiation-induced damage

artículo científico publicado en 1990

A charged-particle microbeam: I. Development of an experimental system for targeting cells individually with counted particles

article

A charged-particle microbeam: II. A single-particle micro-collimation and detection system

artículo científico publicado en 1997

A comparison of the chemical repair rates of free radical precursors of DNA damage and cell killing in Chinese hamster V79 cells

artículo científico publicado en 1992

A comparison of the radiosensitivity of relaxed and supercoiled plasmid DNA

artículo científico publicado en 1999

A computational model of cellular response to modulated radiation fields.

artículo científico publicado en 2012

A focused ultrasoft x-ray microbeam for targeting cells individually with submicrometer accuracy

scientific article published on 01 December 2001

A general mechanistic model enables predictions of the biological effectiveness of different qualities of radiation

artículo científico publicado en 2017

A kinetic-based model of radiation-induced intercellular signalling

artículo científico publicado en 2013

A mechanistic study of gold nanoparticle radiosensitisation using targeted microbeam irradiation.

artículo científico publicado en 2017

A model for radiation-induced bystander effects, with allowance for spatial position and the effects of cell turnover

artículo científico publicado en 2005

A multiple-radical model for radiation action on DNA and the dependence of OER on LET.

artículo científico publicado en 1996

A proliferation-dependent bystander effect in primary porcine and human urothelial explants in response to targeted irradiation.

artículo científico publicado en 2003

A review of the bystander effect and its implications for low-dose exposure ⬇️

artículo científico publicado el 1 de enero de 2003

A scanning focussed vertical ion nanobeam: A new UK facility for cell irradiation and analysis

A study of endonuclease III-sensitive sites in irradiated DNA: detection of alpha-particle-induced oxidative damage

artículo científico publicado en 1999

A study of the biological effects of modulated 6 MV radiation fields.

artículo científico publicado en 2010

ATM Kinase Inhibition Preferentially Sensitises PTEN-Deficient Prostate Tumour Cells to Ionising Radiation

scientific article published on 30 December 2020

ATM acts downstream of ATR in the DNA damage response signaling of bystander cells

artículo científico publicado en 2008

Acute radiation impacts contractility of guinea-pig bladder strips affecting mucosal-detrusor interactions.

artículo científico publicado en 2018

Akt/mTOR mediated induction of bystander effect signaling in a nucleus independent manner in irradiated human lung adenocarcinoma epithelial cells.

artículo científico publicado en 2017

Alpha particles induce pan-nuclear phosphorylation of H2AX in primary human lymphocytes mediated through ATM.

artículo científico publicado en 2015

An arrangement for irradiating cultured mammalian cells with aluminium characteristic ultrasoft X-rays

artículo científico publicado en 1987

An improved method for the treatment of data from DNA strand break measurements using filter elution techniques with an internal standard.

artículo científico publicado en 1989

An in vitro study of the radiobiological effects of flattening filter free radiotherapy treatments.

artículo científico publicado en 2013

An overview of current practice in external beam radiation oncology with consideration to potential benefits and challenges for nanotechnology.

artículo científico publicado en 2017

Antiproton induced DNA damage: proton like in flight, carbon-ion like near rest.

artículo científico publicado en 2013

Application of an Ex Vivo Tissue Model to Investigate Radiobiological Effects on Spermatogenesis.

artículo científico publicado en 2018

Assessing software upgrades, plan properties and patient geometry using intensity modulated radiation therapy (IMRT) complexity metrics

scientific article published on 01 April 2011

Assessment of DNA double-strand breaks induced by intravascular iodinated contrast media following in vitro irradiation and in vivo, during paediatric cardiac catheterization

artículo científico publicado en 2015

BJR radiobiology special feature.

artículo científico publicado en 2014

BRCA1 deficiency exacerbates estrogen-induced DNA damage and genomic instability

artículo científico publicado en 2014

BRCA1, FANCD2 and Chk1 are potential molecular targets for the modulation of a radiation-induced DNA damage response in bystander cells.

artículo científico publicado en 2014

Biological consequences of nanoscale energy deposition near irradiated heavy atom nanoparticles

artículo científico publicado en 2011

Biological mechanisms of gold nanoparticle radiosensitization.

artículo científico publicado en 2017

Bystander effects induced by diffusing mediators after photodynamic stress

artículo científico publicado en 2009

Bystander responses induced by low LET radiation.

artículo científico publicado en 2003

Bystander signaling between glioma cells and fibroblasts targeted with counted particles.

artículo científico publicado en 2005

Bystander-induced differentiation: a major response to targeted irradiation of a urothelial explant model.

artículo científico publicado en 2006

Cell survival responses after exposure to modulated radiation fields.

artículo científico publicado en 2011

Cell type-dependent uptake, localization, and cytotoxicity of 1.9 nm gold nanoparticles.

artículo científico publicado en 2012

Cell-Specific Radiosensitization by Gold Nanoparticles at Megavoltage Radiation Energies ⬇️

artículo científico publicado el 20 de noviembre de 2010

Cellular signalling effects in high precision radiotherapy

artículo científico publicado en 2015

Combined analysis of gamma-H2AX/53BP1 foci and caspase activation in lymphocyte subsets detects recent and more remote radiation exposures

artículo científico publicado en 2013

Comment on 'implications on clinical scenario of gold nanoparticle radiosensitization in regard to photon energy, nanoparticle size, concentration and location'.

artículo científico publicado en 2012

Concise Review: Stem Cell Effects in Radiation Risk ⬇️

artículo científico publicado el 1 de septiembre de 2011

Conventional in vivo irradiation procedures are insufficient to accurately determine tumor responses to non-uniform radiation fields.

artículo científico publicado en 2014

Cytoplasmic irradiation induces mitochondrial-dependent 53BP1 protein relocalization in irradiated and bystander cells.

artículo científico publicado en 2007

DNA DSB Repair Dynamics following Irradiation with Laser-Driven Protons at Ultra-High Dose Rates

artículo científico publicado en 2019

DNA damage responses following exposure to modulated radiation fields

artículo científico publicado en 2012

Deficiencies of double-strand break repair factors and effects on mutagenesis in directly gamma-irradiated and medium-mediated bystander human lymphoblastoid cells.

artículo científico publicado en 2008

Delayed lethality, apoptosis and micronucleus formation in human fibroblasts irradiated with X-rays or alpha-particles.

artículo científico publicado en 1999

Delivering a research-enabled multistakeholder partnership for enhanced patient care at a population level: The Northern Ireland Comprehensive Cancer Program

artículo científico publicado en 2015

Development of a novel experimental model to investigate radiobiological implications of respiratory motion in advanced radiotherapy

artículo científico publicado en 2012

Direct evidence for a bystander effect of ionizing radiation in primary human fibroblasts

artículo científico publicado en 2001

Dose response and kinetics of foci disappearance following exposure to high- and low-LET ionizing radiation.

artículo científico publicado en 2009

Dose, dose-rate and field size effects on cell survival following exposure to non-uniform radiation fields.

artículo científico publicado en 2012

Down-regulation of PERK enhances resistance to ionizing radiation

artículo científico publicado en 2013

Dual effects of radiation bystander signaling in urothelial cancer: purinergic-activation of apoptosis attenuates survival of urothelial cancer and normal urothelial cells.

artículo científico publicado en 2017

ESTRO ACROP: Technology for precision small animal radiotherapy research: Optimal use and challenges.

artículo científico publicado en 2017

Editorial-nanoparticles for diagnostic imaging and radiotherapy.

artículo científico publicado en 2015

Editorial. Non-DNA targeted effects

artículo científico publicado en 2010

Effect of radiation quality on lesion complexity in cellular DNA

artículo científico publicado en 1994

Effective suppression of bystander effects by DMSO treatment of irradiated CHO cells

artículo científico publicado en 2007

Erratum: CORRIGENDUM: Biological consequences of nanoscale energy deposition near irradiated heavy atom nanoparticles

artículo científico publicado en 2013

Estrogen enhanced cell-cell signalling in breast cancer cells exposed to targeted irradiation.

artículo científico publicado en 2008

Evaluating Iodine-125 DNA Damage Benchmarks of Monte Carlo DNA Damage Models

artículo científico publicado en 2022

Evaluation of a Novel Liquid Fiducial Marker, BioXmark®, for Small Animal Image-Guided Radiotherapy Applications

scientific article published on 18 May 2020

Evidence for a hypoxic fixation reaction leading to the induction of ssb and dsb in irradiated DNA

article

Evidence for complexity at the nanometer scale of radiation-induced DNA DSBs as a determinant of rejoining kinetics

article

Evidence for induction of DNA double strand breaks in the bystander response to targeted soft X-rays in CHO cells

artículo científico publicado en 2004

Evidence for induction of DNA double-strand breaks at paired radical sites

article

FLIP: A Targetable Mediator of Resistance to Radiation in Non-Small Cell Lung Cancer.

artículo científico publicado en 2016

Further evidence for double-strand breaks originating from a paired radical precursor from studies of oxygen fixation processes

article

Genomic instability after targeted irradiation of human lymphocytes: evidence for inter-individual differences under bystander conditions.

artículo científico publicado en 2010

Genomic instability in human lymphocytes irradiated with individual charged particles: involvement of tumor necrosis factor alpha in irradiated cells but not bystander cells

artículo científico publicado en 2005

Gold nanoparticle cellular uptake, toxicity and radiosensitisation in hypoxic conditions.

artículo científico publicado en 2014

Gold nanoparticles for cancer radiotherapy: a review

artículo científico publicado en 2016

High dose bystander effects in spatially fractionated radiation therapy

artículo científico publicado en 2013

High-precision microbeam radiotherapy reveals testicular tissue-sparing effects for male fertility preservation

scientific article published on 01 October 2019

Histone H2AX phosphorylation as a molecular pharmacological marker for DNA interstrand crosslink cancer chemotherapy.

artículo científico publicado en 2008

Histone H2AX phosphorylation in normal human cells irradiated with focused ultrasoft X rays: evidence for chromatin movement during repair

artículo científico publicado en 2006

Identification of RBCK1 as a novel regulator of FKBPL: implications for tumor growth and response to tamoxifen.

artículo científico publicado en 2013

Imaging and radiation effects of gold nanoparticles in tumour cells

artículo científico publicado en 2016

Immune modulation in advanced radiotherapies: Targeting out-of-field effects

artículo científico

Impact of fractionation on out-of-field survival and DNA damage responses following exposure to intensity modulated radiation fields

artículo científico publicado en 2015

Implications of intercellular signaling for radiation therapy: a theoretical dose-planning study

artículo científico publicado en 2013

In-vitro investigation of out-of-field cell survival following the delivery of conformal, intensity-modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) plans

artículo científico publicado en 2012

Increased protein ADPribosylation in HeLa cells exposed to the anti-cancer drug methotrexate

artículo científico publicado en 1986

Increased susceptibility to delayed genetic effects of low dose X-irradiation in DNA repair deficient cells.

artículo científico publicado en 2012

Inhibition of ataxia telangiectasia related-3 (ATR) improves therapeutic index in preclinical models of non-small cell lung cancer (NSCLC) radiotherapy.

artículo científico publicado en 2017

Intensity Modulated Radiation Fields Induce Protective Effects and Reduce Importance of Dose-Rate Effects

scientific article published on 01 July 2019

Investigating the Implications of a Variable RBE on Proton Dose Fractionation Across a Clinical Pencil Beam Scanned Spread-Out Bragg Peak

artículo científico publicado en 2016

Investigating the cellular effects of isolated radiation tracks using microbeam techniques

artículo científico publicado en 2002

Investigating the influence of respiratory motion on the radiation induced bystander effect in modulated radiotherapy

artículo científico publicado en 2013

Investigating the potential impact of four-dimensional computed tomography (4DCT) on toxicity, outcomes and dose escalation for radical lung cancer radiotherapy.

artículo científico publicado en 2013

Investigation into the radiobiological consequences of pre-treatment verification imaging with megavoltage X-rays in radiotherapy

artículo científico publicado en 2014

Investigation of dose-rate effects and cell-cycle distribution under protracted exposure to ionizing radiation for various dose-rates.

artículo científico publicado en 2018

Ionizing radiation-induced bystander mutagenesis and adaptation: quantitative and temporal aspects.

artículo científico publicado en 2009

LET-weighted doses effectively reduce biological variability in proton radiotherapy planning

artículo científico publicado en 2018

Local DNA damage by proton microbeam irradiation induces poly(ADP-ribose) synthesis in mammalian cells

scientific article published on 01 September 2003

Low dose effects of ionizing radiation on normal tissue stem cells

artículo científico publicado en 2014

Low-dose binary behavior of bystander cell killing after microbeam irradiation of a single cell with focused c(k) x rays.

artículo científico publicado en 2005

Low-dose hypersensitivity in Chinese hamster V79 cells targeted with counted protons using a charged-particle microbeam

artículo científico publicado en 2001

Low-dose radiation-induced risk in spermatogenesis.

artículo científico publicado en 2017

Low-dose studies of bystander cell killing with targeted soft X rays

artículo científico publicado en 2003

Mechanisms of DNA damage response to targeted irradiation in organotypic 3D skin cultures

artículo científico publicado en 2014

Mechanistic Modeling of Radium-223 Treatment of Bone Metastases

artículo científico publicado en 2018

Mechanistic Modelling of DNA Repair and Cellular Survival Following Radiation-Induced DNA Damage.

artículo científico publicado en 2016

Mechanistic Rationale to Target PTEN-Deficient Tumor Cells with Inhibitors of the DNA Damage Response Kinase ATM.

artículo científico publicado en 2015

Microbeam evolution: from single cell irradiation to pre-clinical studies

artículo científico publicado en 2018

Microbeam studies of the bystander response

artículo científico publicado en 2009

Microsatellite analysis for determination of the mutagenicity of extremely low-frequency electromagnetic fields and ionising radiation in vitro.

artículo científico publicado en 2006

Modelling responses to spatially fractionated radiation fields using preclinical image-guided radiotherapy.

artículo científico publicado en 2016

Multidisciplinary European Low Dose Initiative (MELODI): strategic research agenda for low dose radiation risk research

artículo científico publicado en 2017

Nanodosimetric effects of gold nanoparticles in megavoltage radiation therapy

artículo científico publicado en 2011

New advances in radiation biology.

artículo científico publicado en 2006

New insights into the cellular response to radiation using microbeams

Nitric oxide-mediated signaling in the bystander response of individually targeted glioma cells.

artículo científico publicado en 2003

Non-linear dose-effect curve for DNA double-strand breaks by low LET radiation: the effect of eluting buffer composition on the measurement of breaks by the filter elution technique

article

Non-targeted effects of ionising radiation--implications for low dose risk.

artículo científico publicado en 2012

Non-uniform radiation-induced biological responses at the tissue level involved in the health risk of environmental radiation: a radiobiological hypothesis

article

Nothing endures but change

artículo científico publicado en 2017

Opportunities for research in molecular radiotherapy.

artículo científico publicado en 2017

Optimising element choice for nanoparticle radiosensitisers

artículo científico publicado en 2016

Out-of-field cell survival following exposure to intensity-modulated radiation fields.

artículo científico publicado en 2011

PTEN deficiency promotes macrophage infiltration and hypersensitivity of prostate cancer to IAP antagonist/radiation combination therapy.

artículo científico publicado en 2016

Physical basis and biological mechanisms of gold nanoparticle radiosensitization.

artículo científico

Preclinical evaluation of gold-DTDTPA nanoparticles as theranostic agents in prostate cancer radiotherapy

artículo científico publicado en 2016

Preclinical models of radiation-induced lung damage: challenges and opportunities for small animal radiotherapy

scientific article published on 13 February 2019

Pro-inflammatory Signaling in a 3D Organotypic Skin Model after Low LET Irradiation-NF-κB, COX-2 Activation, and Impact on Cell Differentiation.

artículo científico publicado en 2017

Prostate cancer treated with brachytherapy; an exploratory study of dose-dependent biomarkers and quality of life.

artículo científico publicado en 2017

Protein disulphide isomerase as a target for nanoparticle-mediated sensitisation of cancer cells to radiation

artículo científico publicado en 2016

Quantification of radiation induced DNA double-strand breaks in human fibroblasts by PFGE: testing the applicability of random breakage models

artículo científico publicado en 2002

Radiation effects on the cytoskeleton of endothelial cells and endothelial monolayer permeability

scientific article published on 24 October 2007

Radiation induced bystander signals are independent of DNA damage and DNA repair capacity of the irradiated cells.

artículo científico publicado en 2007

Radiation microbeams as spatial and temporal probes of subcellular and tissue response

artículo científico publicado en 2010

Radiation responses of stem cells: targeted and non-targeted effects.

artículo científico publicado en 2015

Radiation-induced bystander and adaptive responses in cell and tissue models.

artículo científico publicado en 2006

Radiation-induced bystander effects. Mechanisms, biological implications, and current investigations at the Leipzig LIPSION facility.

artículo científico publicado en 2003

Radiation-induced bystander signalling in cancer therapy

artículo científico publicado en 2009

Radiation-induced intercellular signaling mediated by cytochrome-c via a p53-dependent pathway in hepatoma cells ⬇️

artículo científico publicado el 6 de diciembre de 2010

Radiobiological Implications of Fukushima Nuclear Accident for Personalized Medical Approach

artículo científico publicado en 2017

Radioprotection of targeted and bystander cells by methylproamine

artículo científico publicado en 2014

Rates for repair of pBR 322 DNA radicals by thiols as measured by the gas explosion technique: evidence that counter-ion condensation and co-ion depletion are significant at physiological ionic strength

artículo científico publicado en 1991

Real-time imaging of novel spatial and temporal responses to photodynamic stress.

artículo científico publicado en 2009

Relative Biological Effect/Linear Energy Transfer in Proton Beam Therapy: A Primer

scientific article published on 10 July 2019

Relative biological effectiveness (RBE) and out-of-field cell survival responses to passive scattering and pencil beam scanning proton beam deliveries.

artículo científico publicado en 2012

Relative biological effectiveness variation along monoenergetic and modulated Bragg peaks of a 62-MeV therapeutic proton beam: a preclinical assessment.

artículo científico

Reply to 'State of the art in research into the risk of low dose radiation exposure'

artículo científico publicado en 2014

Robustness of differential gene expression analysis of RNA-seq

artículo científico publicado en 2021

Role of TGF-beta1 and nitric oxide in the bystander response of irradiated glioma cells.

artículo científico publicado en 2007

Role of charge in the radioprotection of E. coli by thiols

artículo científico publicado en 1995

Signaling factors for irradiated glioma cells induced bystander responses in fibroblasts.

artículo científico publicado en 2007

Small animal image-guided radiotherapy

artículo científico publicado en 2017

Small animal image-guided radiotherapy: status, considerations and potential for translational impact

artículo científico publicado en 2015

Small field dosimetry for the small animal radiotherapy research platform (SARRP).

artículo científico publicado en 2017

Spatiotemporal investigations of DNA damage repair using microbeams

artículo científico publicado en 2010

State of the art in research into the risk of low dose radiation exposure--findings of the fourth MELODI workshop

artículo científico publicado en 2013

Substrate evaluation for a microbeam endstation using unstained cell imaging.

artículo científico publicado en 2008

Targeted cytoplasmic irradiation induces bystander responses.

scholarly article

Temporal characterization and in vitro comparison of cell survival following the delivery of 3D-conformal, intensity-modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT).

artículo científico publicado en 2011

The Impact of Hypoxia on Out-of-Field Cell Survival after Exposure to Modulated Radiation Fields

artículo científico publicado en 2017

The Irradiation of V79 Mammalian Cells by Protons with Energies below 2 MeV

artículo científico publicado en 1989

The Radiobiology of Proton Therapy: Challenges and Opportunities Around Relative Biological Effectiveness

artículo científico publicado en 2018

The Tissue-Sparing Effect of Spatially Fractionated X-rays for Maintaining Spermatogenesis: A Radiobiological Approach for the Preservation of Male Fertility after Radiotherapy

scientific article published on 11 April 2020

The application of charged-particle microbeams in radiobiology

The irradiation of V79 mammalian cells by protons with energies below 2 MeV. Part II. Measurement of oxygen enhancement ratios and DNA damage

artículo científico publicado en 1990

The relationship between radiation-induced DNA double-strand breaks and cell kill in hamster V79 fibroblasts irradiated with 250 kVp X-rays, 2.3 MeV neutrons or 238Pu alpha-particles

scientific article published on 01 December 1987

The role of PTEN as a cancer biomarker

artículo científico publicado en 2016

The role of mitochondrial function in gold nanoparticle mediated radiosensitisation.

artículo científico publicado en 2014

The role of non-protein sulphydryls in determining the chemical repair rates of free radical precursors of DNA damage and cell killing in Chinese hamster V79 cells

artículo científico publicado el 1 de septiembre de 1992

The use of microbeams to investigate radiation damage in living cells

artículo científico publicado en 2008

The use of theranostic gadolinium-based nanoprobes to improve radiotherapy efficacy.

artículo científico publicado en 2014

Time and Cell Type Dependency of Survival Responses in Co-cultured Tumor and Fibroblast Cells after Exposure to Modulated Radiation Fields

artículo científico publicado en 2015

Time-resolved dosimetric verification of respiratory-gated radiotherapy exposures using a high-resolution 2D ionisation chamber array.

artículo científico publicado en 2016

Use of the γ-H2AX assay to investigate DNA repair dynamics following multiple radiation exposures

artículo científico publicado en 2013

Using the Proton Energy Spectrum and Microdosimetry to Model Proton Relative Biological Effectiveness

scientific article published on 05 February 2019

Validation of a Metastatic Assay using biopsies to improve risk stratification in patients with prostate cancer treated with radical radiation therapy.

artículo científico publicado en 2018

Variations in the Processing of DNA Double-Strand Breaks Along 60-MeV Therapeutic Proton Beams

artículo científico publicado en 2015

What is the Role of the Bystander Response in Radionuclide Therapies?

artículo científico publicado en 2013

What role for DNA damage and repair in the bystander response?

artículo científico publicado en 2006

Workshop Report for Cancer Research: Defining the Shades of Gy: Utilizing the Biological Consequences of Radiotherapy in the Development of New Treatment Approaches-Meeting Viewpoint.

artículo científico publicado en 2018

hSSB1 rapidly binds at the sites of DNA double-strand breaks and is required for the efficient recruitment of the MRN complex

artículo científico publicado en 2010

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