Lista de obras - Bradley W Doble - Dominio Público Uruguay

A CD133-AKT-Wnt signaling axis drives glioblastoma brain tumor-initiating cells

scientific article published on 06 November 2019

A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation

artículo científico publicado en 2005

Abnormalities in brain structure and behavior in GSK-3alpha mutant mice

artículo científico publicado en 2009

BMI1 is a therapeutic target in recurrent medulloblastoma

artículo científico publicado en 2018

Basic fibroblast growth factor stimulates connexin-43 expression and intercellular communication of cardiac fibroblasts

artículo científico publicado en 1995

CUG-initiated FGF-2 induces chromatin compaction in cultured cardiac myocytes and in vitro

article

Calcium protects pituitary basic fibroblast growth factors from limited proteolysis by co-purifying proteases

artículo científico publicado en 1990

Cardiomyocyte gap junctions: a target of growth-promoting signaling

artículo científico publicado en 1998

Deletion of GSK-3beta in mice leads to hypertrophic cardiomyopathy secondary to cardiomyoblast hyperproliferation

artículo científico publicado en 2008

Ectopic γ-catenin expression partially mimics the effects of stabilized β-catenin on embryonic stem cell differentiation

artículo científico publicado en 2013

Exploring pluripotency with chemical genetics

artículo científico publicado en 2009

FGF-2-induced Negative Inotropism and Cardioprotection are Inhibited by Chelerythrine: Involvement of Sarcolemmal Calcium-independent Protein Kinase C

scientific article published on 01 December 1998

Fine-Tuning of the RIG-I-Like Receptor/Interferon Regulatory Factor 3-Dependent Antiviral Innate Immune Response by the Glycogen Synthase Kinase 3/β-Catenin Pathway

artículo científico publicado en 2015

Functional redundancy of GSK-3alpha and GSK-3beta in Wnt/beta-catenin signaling shown by using an allelic series of embryonic stem cell lines

artículo científico publicado en 2007

GSK-3 is a master regulator of neural progenitor homeostasis

artículo científico publicado en 2009

GSK-3: tricks of the trade for a multi-tasking kinase

artículo científico publicado en 2003

GSK-3alpha directly regulates beta-adrenergic signaling and the response of the heart to hemodynamic stress in mice

scientific journal article

GSK3 Deficiencies in Hematopoietic Stem Cells Initiate Pre-neoplastic State that Is Predictive of Clinical Outcomes of Human Acute Leukemia.

artículo científico publicado en 2016

Genetic deficiency of glycogen synthase kinase-3beta corrects diabetes in mouse models of insulin resistance

artículo científico publicado en 2008

Glycogen synthase kinase 3, circadian rhythms, and bipolar disorder: a molecular link in the therapeutic action of lithium

artículo científico publicado en 2007

Glycogen synthase kinase 3alpha-specific regulation of murine hepatic glycogen metabolism

artículo científico publicado en 2007

Glycogen synthase kinase-3 (Gsk-3) plays a fundamental role in maintaining DNA methylation at imprinted loci in mouse embryonic stem cells

artículo científico publicado en 2015

IL-17 receptor signaling inhibits C/EBPbeta by sequential phosphorylation of the regulatory 2 domain

artículo científico publicado en 2009

Inhibition of TGFbeta signaling potentiates the FGF-2-induced stimulation of cardiomyocyte DNA synthesis

scientific journal article

Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions.

artículo científico publicado en 2007

Medulloblastoma stem cells: modeling tumor heterogeneity.

artículo científico publicado en 2012

Medulloblastoma stem cells: where development and cancer cross pathways.

artículo científico

Over-expression of CUG- or AUG-initiated Forms of Basic Fibroblast Growth Factor in Cardiac Myocytes Results in Similar Effects on Mitosis and Protein Synthesis but Distinct Nuclear Morphologies

artículo científico publicado en 1994

Phosphatidylinositol 3-kinase (PI3K) signaling via glycogen synthase kinase-3 (Gsk-3) regulates DNA methylation of imprinted loci

scientific journal article

Phosphorylation by p38 MAPK as an alternative pathway for GSK3beta inactivation.

scientific article published on May 2008

Phosphorylation of serine 262 in the gap junction protein connexin-43 regulates DNA synthesis in cell-cell contact forming cardiomyocytes

scientific journal article

Prevention of amino acid conversion in SILAC experiments with embryonic stem cells.

artículo científico publicado en 2008

Pyrvinium Targets CD133 in Human Glioblastoma Brain Tumor-Initiating Cells.

artículo científico publicado en 2015

R-spondin1 is a high affinity ligand for LRP6 and induces LRP6 phosphorylation and beta-catenin signaling

artículo científico publicado en 2007

Regulation of basic fibroblast growth factor (bFGF) and FGF receptors in the heart.

artículo científico publicado en 1995

Role of glycogen synthase kinase-3 in cell fate and epithelial-mesenchymal transitions

artículo científico publicado en 2007

Selective monoclonal antibody recognition and cellular localization of an unphosphorylated form of connexin43.

artículo científico publicado en 1997

The carboxy-tail of connexin-43 localizes to the nucleus and inhibits cell growth

artículo científico publicado en 2003

The responses of neural stem cells to the level of GSK-3 depend on the tissue of origin

artículo científico publicado en 2013

Tissue-specific role of glycogen synthase kinase 3beta in glucose homeostasis and insulin action

artículo científico publicado en 2008

Wnt activation as a therapeutic strategy in medulloblastoma

scientific article published on 28 August 2020

β-Catenin Enhances Oct-4 Activity and Reinforces Pluripotency through a TCF-Independent Mechanism ⬇️

artículo científico publicado el 4 de febrero de 2011

β-Catenin safeguards the ground state of mousepluripotency by strengthening the robustness of the transcriptional apparatus

scientific article published on 17 July 2020

Lista de obras de Bradley W Doble

A CD133-AKT-Wnt signaling axis drives glioblastoma brain tumor-initiating cells

A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation

Abnormalities in brain structure and behavior in GSK-3alpha mutant mice

BMI1 is a therapeutic target in recurrent medulloblastoma

Basic fibroblast growth factor stimulates connexin-43 expression and intercellular communication of cardiac fibroblasts

CUG-initiated FGF-2 induces chromatin compaction in cultured cardiac myocytes and in vitro

Calcium protects pituitary basic fibroblast growth factors from limited proteolysis by co-purifying proteases

Cardiomyocyte gap junctions: a target of growth-promoting signaling

Deletion of GSK-3beta in mice leads to hypertrophic cardiomyopathy secondary to cardiomyoblast hyperproliferation

Ectopic γ-catenin expression partially mimics the effects of stabilized β-catenin on embryonic stem cell differentiation

Exploring pluripotency with chemical genetics

FGF-2-induced Negative Inotropism and Cardioprotection are Inhibited by Chelerythrine: Involvement of Sarcolemmal Calcium-independent Protein Kinase C

Fine-Tuning of the RIG-I-Like Receptor/Interferon Regulatory Factor 3-Dependent Antiviral Innate Immune Response by the Glycogen Synthase Kinase 3/β-Catenin Pathway

Functional redundancy of GSK-3alpha and GSK-3beta in Wnt/beta-catenin signaling shown by using an allelic series of embryonic stem cell lines

GSK-3 is a master regulator of neural progenitor homeostasis

GSK-3: tricks of the trade for a multi-tasking kinase

GSK-3alpha directly regulates beta-adrenergic signaling and the response of the heart to hemodynamic stress in mice

GSK3 Deficiencies in Hematopoietic Stem Cells Initiate Pre-neoplastic State that Is Predictive of Clinical Outcomes of Human Acute Leukemia.

Genetic deficiency of glycogen synthase kinase-3beta corrects diabetes in mouse models of insulin resistance

Glycogen synthase kinase 3, circadian rhythms, and bipolar disorder: a molecular link in the therapeutic action of lithium

Glycogen synthase kinase 3alpha-specific regulation of murine hepatic glycogen metabolism

Glycogen synthase kinase-3 (Gsk-3) plays a fundamental role in maintaining DNA methylation at imprinted loci in mouse embryonic stem cells

IL-17 receptor signaling inhibits C/EBPbeta by sequential phosphorylation of the regulatory 2 domain

Inhibition of TGFbeta signaling potentiates the FGF-2-induced stimulation of cardiomyocyte DNA synthesis

Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions.

Medulloblastoma stem cells: modeling tumor heterogeneity.

Medulloblastoma stem cells: where development and cancer cross pathways.

Over-expression of CUG- or AUG-initiated Forms of Basic Fibroblast Growth Factor in Cardiac Myocytes Results in Similar Effects on Mitosis and Protein Synthesis but Distinct Nuclear Morphologies

Phosphatidylinositol 3-kinase (PI3K) signaling via glycogen synthase kinase-3 (Gsk-3) regulates DNA methylation of imprinted loci

Phosphorylation by p38 MAPK as an alternative pathway for GSK3beta inactivation.

Phosphorylation of serine 262 in the gap junction protein connexin-43 regulates DNA synthesis in cell-cell contact forming cardiomyocytes

Prevention of amino acid conversion in SILAC experiments with embryonic stem cells.

Pyrvinium Targets CD133 in Human Glioblastoma Brain Tumor-Initiating Cells.

R-spondin1 is a high affinity ligand for LRP6 and induces LRP6 phosphorylation and beta-catenin signaling

Regulation of basic fibroblast growth factor (bFGF) and FGF receptors in the heart.

Role of glycogen synthase kinase-3 in cell fate and epithelial-mesenchymal transitions

Selective monoclonal antibody recognition and cellular localization of an unphosphorylated form of connexin43.

The carboxy-tail of connexin-43 localizes to the nucleus and inhibits cell growth

The responses of neural stem cells to the level of GSK-3 depend on the tissue of origin

Tissue-specific role of glycogen synthase kinase 3beta in glucose homeostasis and insulin action

Wnt activation as a therapeutic strategy in medulloblastoma

β-Catenin Enhances Oct-4 Activity and Reinforces Pluripotency through a TCF-Independent Mechanism ⬇️

β-Catenin safeguards the ground state of mousepluripotency by strengthening the robustness of the transcriptional apparatus