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Lista de obras de Manuel R. Teixeira

12q amplification defines a subtype of extraskeletal osteosarcoma with good prognosis that is the soft tissue homologue of parosteal osteosarcoma.

artículo científico publicado en 2012

8q Gain Is an Independent Predictor of Poor Survival in Diagnostic Needle Biopsies from Prostate Cancer Suspects

artículo científico publicado en 2006

8q24 Copy number gains and expression of the c-myc mRNA stabilizing protein CRD-BP in primary breast carcinomas

artículo científico publicado en 2003

A Large-Scale Analysis of Genetic Variants within Putative miRNA Binding Sites in Prostate Cancer

artículo científico publicado en 2015

A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk

article

A genetic risk score to guide age-specific, personalized prostate cancer screening

A genetic risk score to personalize prostate cancer screening, applied to population data

scientific article published on 24 June 2020

A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer

artículo científico publicado en 2014

A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease

artículo científico publicado en 2012

A network analysis to identify mediators of germline-driven differences in breast cancer prognosis

artículo científico publicado en 2020

A novel MLL-SEPT2 fusion variant in therapy-related myelodysplastic syndrome

artículo científico publicado en 2008

A novel exonic rearrangement affecting MLH1 and the contiguous LRRFIP2 is a founder mutation in Portuguese Lynch syndrome families

artículo científico publicado en 2011

A novel spliced fusion of MLL with CT45A2 in a pediatric biphenotypic acute leukemia. ⬇️

artículo científico publicado en 2010

A quantitative promoter methylation profile of prostate cancer.

artículo científico publicado en 2004

A universal assay for detection of oncogenic fusion transcripts by oligo microarray analysis

artículo científico publicado en 2009

AA9int: SNP interaction pattern search using non-hierarchical additive model set

ADAMTS1, CRABP1, and NR3C1 identified as epigenetically deregulated genes in colorectal tumorigenesis.

artículo científico publicado en 2006

Aberrant cellular retinol binding protein 1 (CRBP1) gene expression and promoter methylation in prostate cancer

artículo científico publicado en 2004

Acute megakaryoblastic leukemia with a four-way variant translocation originating the RBM15-MKL1 fusion gene

artículo científico publicado en 2011

Acute myeloid leukemia with inv(8)(p11q13).

artículo científico publicado en 2000

Adenomas and follicular carcinomas of the thyroid display two major patterns of chromosomal changes

scientific article published on 01 July 2005

After Angelina and the Supreme Court Decision, where do we go from here? BRCA gene testing in Rhode Island's Portuguese population.

artículo científico publicado en 2013

Alcohol consumption and prostate cancer incidence and progression: A Mendelian randomisation study

artículo científico publicado en 2016

Altered expression of MGMT in high-grade gliomas results from the combined effect of epigenetic and genetic aberrations

artículo científico publicado en 2013

Altered expression of key cell cycle regulators in renal cell carcinoma associated with Xp11.2 translocation.

artículo científico publicado en 2009

An original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriers

artículo científico publicado en 2015

Analysis of Founder Mutations in Rare Tumors Associated With Hereditary Breast/Ovarian Cancer Reveals a Novel Association of BRCA2 Mutations with Ampulla of Vater Carcinomas

artículo científico publicado en 2016

Are some breast carcinomas polyclonal in origin?

artículo científico publicado en 2001

Array CGH and gene-expression profiling reveals distinct genomic instability patterns associated with DNA repair and cell-cycle checkpoint pathways in Ewing's sarcoma.

artículo científico publicado en 2007

Assessing associations between the AURKA-HMMR-TPX2-TUBG1 functional module and breast cancer risk in BRCA1/2 mutation carriers

artículo científico publicado en 2015

Assessing the role of insulin-like growth factors and binding proteins in prostate cancer using Mendelian randomization: Genetic variants as instruments for circulating levels

artículo científico publicado en 2016

Assessment of clonal relationships in ipsilateral and bilateral multiple breast carcinomas by comparative genomic hybridisation and hierarchical clustering analysis

artículo científico publicado en 2004

Assessment of fusion gene status in sarcomas using a custom made fusion gene microarray

artículo científico publicado en 2013

Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

artículo científico publicado en 2018

Association of ERBB2 gene status with histopathological parameters and disease-specific survival in gastric carcinoma patients

scientific article published on 20 January 2009

Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness

artículo científico publicado en 2019

Association of breast cancer risk in BRCA1 and BRCA2 mutation carriers with genetic variants showing differential allelic expression: identification of a modifier of breast cancer risk at locus 11q22.3.

artículo científico publicado en 2016

Association of germline variation with the survival of women with BRCA1/2 pathogenic variants and breast cancer

scientific article published on 10 September 2020

Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer

artículo científico publicado en 2015

Associations of common breast cancer susceptibility alleles with risk of breast cancer subtypes in BRCA1 and BRCA2 mutation carriers

artículo científico publicado en 2014

Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation

artículo científico publicado en 2016

Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

scholarly article published in Nature Genetics

Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

scholarly article published in Nature Genetics

Author Correction: Germline variation at 8q24 and prostate cancer risk in men of European ancestry

scientific article published in Nature Communications

BMP2/BMP4 colorectal cancer susceptibility loci in northern and southern European populations

artículo científico publicado en 2012

BRCA1 and BRCA2 germline mutational spectrum and evidence for genetic anticipation in Portuguese breast/ovarian cancer families.

artículo científico publicado en 2006

BRCA1 and BRCA2 rearrangements in Brazilian individuals with Hereditary Breast and Ovarian Cancer Syndrome.

artículo científico publicado en 2016

BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers

artículo científico publicado en 2015

Blood lipids and prostate cancer: a Mendelian randomization analysis

artículo científico publicado en 2016

Both SEPT2 and MLL are down-regulated in MLL-SEPT2 therapy-related myeloid neoplasia

artículo científico publicado en 2009

Breast and Prostate Cancer Risks for Male BRCA1 and BRCA2 Pathogenic Variant Carriers Using Polygenic Risk Scores

artículo científico publicado en 2022

Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170.

artículo científico publicado en 2016

CSF1R copy number changes, point mutations, and RNA and protein overexpression in renal cell carcinomas

artículo científico publicado en 2009

Cancer Prognosis Defined by the Combined Analysis of 8q, PTEN and ERG.

artículo científico publicado en 2016

Candidate genetic modifiers for breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers

artículo científico publicado en 2014

Carcinoma of the thyroid with Ewing/PNET family tumor elements: a tumor of unknown histogenesis

artículo científico publicado en 2013

Carcinoma of the thyroid with ewing family tumor elements and favorable prognosis: report of a second case

artículo científico publicado en 2013

Cernunnos influences human immunoglobulin class switch recombination and may be associated with B cell lymphomagenesis

artículo científico publicado en 2012

Characterization of supernumerary rings and giant marker chromosomes in well-differentiated lipomatous tumors by a combination of G-banding, CGH, M-FISH, and chromosome- and locus-specific FISH

scientific article published on 01 January 2002

Chromosome Mechanisms Giving Rise to the TMPRSS2-ERG Fusion Oncogene in Prostate Cancer and HGPIN Lesions

scientific article published on 01 April 2008

Chromosome abnormalities in benign hyperproliferative disorders of epithelial and stromal breast tissue

artículo científico publicado en 1995

Chromosome abnormalities in bilateral breast carcinomas. Cytogenetic evaluation of the clonal origin of multiple primary tumors.

artículo científico

Chromosome analysis and molecular cytogenetic investigations of an epithelioid hemangioendothelioma

scientific article published on 01 September 2006

Chromosome copy number changes carry prognostic information independent of KIT/PDGFRA point mutations in gastrointestinal stromal tumors

artículo científico publicado en 2010

Circulating Metabolic Biomarkers of Screen-Detected Prostate Cancer in the ProtecT Study

artículo científico publicado en 2018

Clonal heterogeneity in breast cancer: Karyotypic comparisons of multiple intra—and extra—tumorous samples from 3 patients

artículo científico publicado en 1995

Co-occurrence of nonsense mutations in MSH6 and MSH2 in Lynch syndrome families evidencing that not all truncating mutations are equal

artículo científico publicado en 2015

Coexistence of alternative MLL–SEPT9 fusion transcripts in an acute myeloid leukemia with t(11;17)(q23;q25)

artículo científico publicado en 2010

Colorectal carcinomas with microsatellite instability display a different pattern of target gene mutations according to large bowel site of origin

artículo científico publicado en 2010

Combined RxFISH/G-banding allows refined karyotyping of solid tumors

artículo científico

Combined classical and molecular cytogenetic analysis of cancer.

artículo científico publicado en 2002

Common fusion transcripts identified in colorectal cancer cell lines by high-throughput RNA sequencing

artículo científico publicado en 2013

Comparison of chromosomal and array-based comparative genomic hybridization for the detection of genomic imbalances in primary prostate carcinomas

artículo científico publicado en 2006

Comparison of methodologies for KRAS mutation detection in metastatic colorectal cancer

artículo científico publicado en 2011

Complete cytogenetic characterization of the human breast cancer cell line MA11 combining G-banding, comparative genomic hybridization, multicolor fluorescence in situ hybridization, RxFISH, and chromosome-specific painting

artículo científico publicado en 2001

Constitutional and somatic rearrangement of chromosome 21 in acute lymphoblastic leukaemia

artículo científico publicado en 2014

Contribution of MLH1 constitutional methylation for Lynch syndrome diagnosis in patients with tumor MLH1 downregulation

artículo científico publicado en 2018

Conventional and molecular cytogenetics of human non-medullary thyroid carcinoma: characterization of eight cell line models and review of the literature on clinical samples

artículo científico publicado en 2008

Correspondence: SEMA4A variation and risk of colorectal cancer

artículo científico publicado en 2016

Cryptic chromosome rearrangement resulting in SYT-SSX2 fusion gene in a monophasic synovial sarcoma

article

Cyclin D1 A870G polymorphism and amplification in laryngeal squamous cell carcinoma: implications of tumor localization and tobacco exposure.

artículo científico publicado en 2004

Cysteine-rich secretory protein-3 (CRISP3) is strongly up-regulated in prostate carcinomas with the TMPRSS2-ERG fusion gene

artículo científico publicado en 2011

Cytogenetic abnormalities in anin situ ductal carcinoma and five prophylactically removed breasts from members of a family with hereditary breast cancer

artículo científico publicado en 1996

Cytogenetic analysis of multifocal breast carcinomas: detection of karyotypically unrelated clones as well as clonal similarities between tumour foci.

artículo científico publicado en 1994

Cytogenetic analysis of several pseudomyxoma peritonei lesions originating from a mucinous cystadenoma of the appendix

artículo científico publicado en 1997

Cytogenetic analysis of tumor clonality

artículo científico

Cytogenetic and molecular genetic analyses of endometrial stromal sarcoma: nonrandom involvement of chromosome arms 6p and 7p and confirmation of JAZF1/JJAZ1 gene fusion in t(7;17)

article

Cytogenetic characterization of tumors of the vulva and vagina

artículo científico publicado en 2003

Cytogenetic clues to breast carcinogenesis

artículo científico publicado en 2002

Cytogenetic comparison of primary tumors and lymph node metastases in breast cancer patients

artículo científico publicado en 1998

Cytogenetic polyclonality in tumors of the breast.

artículo científico publicado en 1997

DNA glycosylases involved in base excision repair may be associated with cancer risk in BRCA1 and BRCA2 mutation carriers

artículo científico publicado en 2014

DNA repair genes are selectively mutated in diffuse large B cell lymphomas

artículo científico publicado en 2013

Deregulation of PAX2 expression in renal cell tumours: mechanisms and potential use in differential diagnosis

scientific article published on 26 July 2013

Desmoplastic small round cell tumor: diagnosis by fine-needle aspiration cytology

artículo científico publicado en 2012

Detailed analysis of expression and promoter methylation status of apoptosis-related genes in prostate cancer

artículo científico publicado en 2010

Detailed genome-wide screening for inter- and intrachromosomal abnormalities by sequential G-banding and RxFISH color banding of the same metaphase cells

artículo científico

Detection of gene promoter hypermethylation in fine needle washings from breast lesions.

artículo científico publicado en 2003

Discontinuation of tyrosine kinase inhibitors in CML patients in real-world clinical practice at a single institution

artículo científico publicado en 2018

Discrimination between multicentric and multifocal breast carcinoma by cytogenetic investigation of macroscopically distinct ipsilateral lesions

artículo científico publicado en 1997

Distinct high resolution genome profiles of early onset and late onset colorectal cancer integrated with gene expression data identify candidate susceptibility loci

artículo científico publicado en 2010

Distinct patterns of KRAS mutations in colorectal carcinomas according to germline mismatch repair defects and hMLH1 methylation status

artículo científico publicado en 2004

EGFR exon mutation distribution and outcome in non-small-cell lung cancer: a Portuguese retrospective study

artículo científico publicado en 2012

Endometrial endometrioid adenocarcinoma associated with primitive neuroectodermal tumour of the uterus: a poor prognostic subtype of uterine tumours

scientific article published on 29 May 2010

Epigenetic heterogeneity of high-grade prostatic intraepithelial neoplasia: clues for clonal progression in prostate carcinogenesis.

artículo científico publicado en 2006

Epigenetic regulation of EFEMP1 in prostate cancer: biological relevance and clinical potential

artículo científico publicado en 2014

Epigenetic regulation of Wnt signaling pathway in urological cancer

artículo científico publicado en 2010

Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers

artículo científico publicado en 2017

Evaluation of breast cancer polyclonality by combined chromosome banding and comparative genomic hybridization analysis

artículo científico publicado en 2001

Exome sequencing reveals novel mutation targets in diffuse large B-cell lymphomas derived from Chinese patients.

artículo científico publicado en 2014

Expression changes of the MAD mitotic checkpoint gene family in renal cell carcinomas characterized by numerical chromosome changes

artículo científico publicado en 2007

Expression pattern of the septin gene family in acute myeloid leukemias with and without MLL-SEPT fusion genes.

artículo científico publicado en 2009

FLI1 is a novel ETS transcription factor involved in gene fusions in prostate cancer

artículo científico publicado en 2011

FOXE1 polymorphisms are associated with familial and sporadic nonmedullary thyroid cancer susceptibility

artículo científico publicado en 2012

Familial vs sporadic papillary thyroid carcinoma: a matched-case comparative study showing similar clinical/prognostic behaviour

artículo científico publicado en 2013

Feasibility of differential diagnosis of kidney tumors by comparative genomic hybridization of fine needle aspiration biopsies

artículo científico publicado en 2010

Fine-Scale Mapping at 9p22.2 Identifies Candidate Causal Variants That Modify Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

artículo científico publicado en 2016

Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression

artículo científico publicado en 2013

Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression.

artículo científico publicado en 2013

Fine-mapping of 150 breast cancer risk regions identifies 178 high confidence target genes

article

Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

artículo científico publicado en 2020

Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants.

artículo científico publicado en 2018

Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk

artículo científico publicado en 2014

Fine-mapping the HOXB region detects common variants tagging a rare coding allele: evidence for synthetic association in prostate cancer

artículo científico publicado en 2014

Fluorescence in situ hybridization of old G-banded and mounted chromosome preparations

artículo científico

Frequency of NUP98-NSD1 fusion transcript in childhood acute myeloid leukaemia

artículo científico publicado en 2003

Frequent 14-3-3 sigma promoter methylation in benign and malignant prostate lesions

artículo científico publicado en 2005

Frequent alterations in cytoskeleton remodelling genes in primary and metastatic lung adenocarcinomas

artículo científico publicado en 2015

Frequent copy number gains at 1q21 and 1q32 are associated with overexpression of the ETS transcription factors ETV3 and ELF3 in breast cancer irrespective of molecular subtypes

artículo científico publicado en 2013

Full in-frame exon 3 skipping of BRCA2 confers high risk of breast and/or ovarian cancer.

artículo científico publicado en 2018

Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus

artículo científico publicado en 2016

Gene Panel Tumor Testing in Ovarian Cancer Patients Significantly Increases the Yield of Clinically Actionable Germline Variants beyond BRCA1/BRCA2

scientific article published on 30 September 2020

Gene amplification of the histone methyltransferase SETDB1 contributes to human lung tumorigenesis

artículo científico publicado en 2013

Gene and pathway level analyses of germline DNA-repair gene variants and prostate cancer susceptibility using the iCOGS-genotyping array

artículo científico publicado en 2016

Gene and pathway level analyses of germline DNA-repair gene variants and prostate cancer susceptibility using the iCOGS-genotyping array

artículo científico publicado en 2018

Genetic Testing and Clinical Management Practices for Variants in Non-BRCA1/2 Breast (and Breast/Ovarian) Cancer Susceptibility Genes: An International Survey by the Evidence-Based Network for the Interpretation of Germline Mutant Alleles (ENIGMA) C

scientific article published on 26 October 2018

Genetic and clinical characterization of 45 acute leukemia patients with MLL gene rearrangements from a single institution.

artículo científico publicado en 2012

Genetic basis of PD-L1 overexpression in diffuse large B-cell lymphomas

artículo científico publicado en 2016

Genetic counselling and testing of susceptibility genes for therapeutic decision-making in breast cancer—an European consensus statement and expert recommendations

article

Genetic diagnosis of alveolar rhabdomyosarcoma in the bone marrow of a patient without evidence of primary tumor

artículo científico publicado en 2008

Genetic profiling of colorectal cancer liver metastases by combined comparative genomic hybridization and G-banding analysis.

artículo científico publicado en 2003

Genome characteristics of primary carcinomas, local recurrences, carcinomatoses, and liver metastases from colorectal cancer patients

artículo científico publicado en 2004

Genome profiling of breast cancer cells selected against in vitro shows copy number changes

artículo científico publicado en 2002

Genome signatures of colon carcinoma cell lines

artículo científico publicado en 2004

Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types

artículo científico publicado en 2016

Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer

article

Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses

scientific article published on 18 May 2020

Genome-wide association study of germline variants and breast cancer-specific mortality

artículo científico publicado en 2019

Genome-wide association study of prostate cancer-specific survival

artículo científico publicado en 2015

Genomic aberrations in carcinomas of the uterine corpus

scientific article published on 01 July 2004

Genomic analysis of prostate carcinoma specimens obtained via ultrasound-guided needle biopsy may be of use in preoperative decision-making

artículo científico publicado en 2004

Genomic changes in chromosomes 10, 16, and X in malignant peripheral nerve sheath tumors identify a high-risk patient group

artículo científico publicado en 2010

Genomic characterization of two large Alu-mediated rearrangements of the BRCA1 gene

artículo científico publicado en 2012

Genotypic and phenotypic classification of cancer: How should the impact of the two diagnostic approaches best be balanced?

artículo científico

Germline Mutations in PALB2, BRCA1, and RAD51C, Which Regulate DNA Recombination Repair, in Patients With Gastric Cancer

artículo científico publicado en 2016

Germline pathogenic variants in PALB2 and other cancer-predisposing genes in families with hereditary diffuse gastric cancer without CDH1 mutation: a whole-exome sequencing study.

artículo científico publicado en 2018

Germline variation at 8q24 and prostate cancer risk in men of European ancestry

artículo científico publicado en 2018

Haplotype and quantitative transcript analyses of Portuguese breast/ovarian cancer families with the BRCA1 R71G founder mutation of Galician origin

artículo científico publicado en 2009

Height and Body Mass Index as Modifiers of Breast Cancer Risk in BRCA1/2 Mutation Carriers: A Mendelian Randomization Study

artículo científico publicado en 2019

Hereditary Predisposition to Prostate Cancer: From Genetics to Clinical Implications

scientific article published on 16 July 2020

Hereditary gastrointestinal stromal tumors sharing the KIT Exon 17 germline mutation p.Asp820Tyr develop through different cytogenetic progression pathways

artículo científico publicado en 2009

Heterogeneous genetic profiles in soft tissue myoepitheliomas

artículo científico publicado en 2008

High promoter methylation levels of APC predict poor prognosis in sextant biopsies from prostate cancer patients.

artículo científico publicado en 2007

High resolution melting analysis of KRAS, BRAF and PIK3CA in KRAS exon 2 wild-type metastatic colorectal cancer

artículo científico publicado en 2013

Highly sensitive detection of the MGB1 transcript (mammaglobin) in the peripheral blood of breast cancer patients

artículo científico publicado en 2004

Hybrid oncocytic/chromophobe renal cell tumor: An integrated genetic and epigenetic characterization of a case

scientific article published on 18 October 2018

Hyperdiploidy with 58-66 chromosomes in childhood B-acute lymphoblastic leukemia is highly curable: 58951 CLG-EORTC results.

artículo científico publicado en 2013

Hypermethylation of Cyclin D2 is associated with loss of mRNA expression and tumor development in prostate cancer

artículo científico publicado en 2006

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

artículo científico publicado en 2017

Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array

artículo científico publicado en 2013

Identification of Two Novel HOXB13 Germline Mutations in Portuguese Prostate Cancer Patients

artículo científico publicado en 2015

Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer

artículo científico publicado en 2016

Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus

artículo científico publicado en 2016

Identification of previously unrecognized FAP in children with Gardner fibroma

artículo científico publicado en 2014

Identification of six new susceptibility loci for invasive epithelial ovarian cancer

artículo científico publicado en 2015

Identification of somatic TERT promoter mutations in familial nonmedullary thyroid carcinomas

artículo científico publicado en 2017

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer

artículo científico publicado en 2017

Immunohistochemical molecular phenotypes of gastric cancer based on SOX2 and CDX2 predict patient outcome

artículo científico publicado en 2014

Implementation of next-generation sequencing for molecular diagnosis of hereditary breast and ovarian cancer highlights its genetic heterogeneity

artículo científico publicado en 2016

Inheritance of deleterious mutations at both BRCA1 and BRCA2 in an international sample of 32,295 women

artículo científico publicado en 2016

Interim Results from the IMPACT Study: Evidence for Prostate-specific Antigen Screening in BRCA2 Mutation Carriers

artículo científico publicado en 2019

International distribution and age estimation of the Portuguese BRCA2 c.156_157insAlu founder mutation.

artículo científico publicado en 2010

Intraepidermal epidermotropic metastatic melanoma: a clinical and histopathological mimicker of melanoma in situ occurring in multiplicity

artículo científico publicado en 2011

Intratumor genomic heterogeneity in breast cancer with clonal divergence between primary carcinomas and lymph node metastases

artículo científico publicado en 2006

Investigating the possible causal role of coffee consumption with prostate cancer risk and progression using Mendelian randomization analysis

artículo científico publicado en 2016

Karyotypic Evolution in Breast Carcinomas with i(1)(q10) and der(1;16)(q10;p10) as the Primary Chromosome Abnormality

scientific article published on 01 September 1999

Karyotypic Findings in Tumors of the Vulva and Vagina

artículo científico publicado en 1999

Karyotypic changes in phyllodes tumors of the breast

scientific article published on 01 December 1994

Karyotypic comparisons of multiple tumorous and macroscopically normal surrounding tissue samples from patients with breast cancer

artículo científico publicado en 1996

Karyotypic divergence and convergence in two synchronous lung metastases of a clear cell sarcoma of tendons and aponeuroses with t(12;22)(q13;q12) and type 1 EWS/ATF1.

artículo científico publicado en 2003

Lapatinib-capecitabine versus capecitabine alone as radiosensitizers in RAS wild-type resectable rectal cancer, an adaptive randomized phase II trial (LaRRC trial): study protocol for a randomized controlled trial

artículo científico publicado en 2016

Li-Fraumeni-like syndrome associated with a large BRCA1 intragenic deletion

artículo científico publicado en 2012

MLL-SEPTIN gene fusions in hematological malignancies

artículo científico publicado en 2011

MSH6 germline mutations in early-onset colorectal cancer patients without family history of the disease

artículo científico publicado en 2006

MT1G hypermethylation is associated with higher tumor stage in prostate cancer

artículo científico publicado en 2005

Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2.

artículo científico publicado en 2016

Mendelian randomisation study of height and body mass index as modifiers of ovarian cancer risk in 22,588 BRCA1 and BRCA2 mutation carriers

scientific article published on 19 June 2019

Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1.

artículo científico publicado en 2015

Mitochondrial DNA-control region sequence variation in the NE Portuguese Jewish community

article

Mitochondrial genome alterations in rectal and sigmoid carcinomas

artículo científico publicado en 2009

Molecular characterization of a rare MLL–AF4 (MLL–AFF1) fusion rearrangement in infant leukemia

artículo científico publicado en 2007

Molecular characterization of the MLL-SEPT6 fusion gene in acute myeloid leukemia: identification of novel fusion transcripts and cloning of genomic breakpoint junctions

artículo científico publicado en 2008

Molecular circuit involving KLK4 integrates androgen and mTOR signaling in prostate cancer.

artículo científico publicado en 2013

Molecular cytogenetic characterization of proximal-type epithelioid sarcoma

artículo científico publicado en 2004

Molecular diagnosis of the Portuguese founder mutation BRCA2 c.156_157insAlu.

artículo científico publicado en 2008

Molecular subtyping of primary prostate cancer reveals specific and shared target genes of different ETS rearrangements

artículo científico publicado en 2012

Multimodal genetic diagnosis of solid variant alveolar rhabdomyosarcoma.

artículo científico publicado en 2005

Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans

artículo científico publicado en 2015

Multiple numerical chromosome aberrations in cancer: what are their causes and what are their consequences?

artículo científico publicado en 2005

Mutational Spectrum in a Worldwide Study of 29,700 Families with BRCA1 or BRCA2 Mutations

artículo científico publicado en 2018

Mutations in exon 14 of dihydropyrimidine dehydrogenase and 5-Fluorouracil toxicity in Portuguese colorectal cancer patients

artículo científico publicado en 2004

Myeloid Disease with the CSF3R T618I Mutation after CLL

artículo científico publicado en 2020

NCOA2 is a candidate target gene of 8q gain associated with clinically aggressive prostate cancer.

artículo científico publicado en 2016

Negative MR4·0 chronic myeloid leukaemia and its possible implications for treatment-free remission

artículo científico publicado en 2019

No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer.

artículo científico publicado en 2015

No significant role for beta tubulin mutations and mismatch repair defects in ovarian cancer resistance to paclitaxel/cisplatin

artículo científico publicado en 2005

Novel 5' fusion partners of ETV1 and ETV4 in prostate cancer

artículo científico publicado en 2013

Oncogenic mechanisms of HOXB13 missense mutations in prostate carcinogenesis.

artículo científico publicado en 2016

Ovarian metastasis from uveal melanoma with MLH1/PMS2 protein loss in a patient with germline MLH1 mutated Lynch syndrome: consequence or coincidence?

artículo científico publicado en 2016

Overexpression of the mitotic checkpoint genes BUB1 and BUBR1 is associated with genomic complexity in clear cell kidney carcinomas.

artículo científico publicado en 2008

PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS

artículo científico publicado en 2016

PNET with neuroendocrine differentiation of the lung: Report of an unusual entity.

artículo científico publicado en 2013

POLE somatic mutations in advanced colorectal cancer

artículo científico publicado en 2017

POU1F1 is a novel fusion partner of NUP98 in acute myeloid leukemia with t(3;11)(p11;p15).

artículo científico publicado en 2013

Pathogenicity evaluation of BRCA1 and BRCA2 unclassified variants identified in Portuguese breast/ovarian cancer families

artículo científico publicado en 2014

Pathologic Findings in Prophylactic and Nonprophylactic Hysterectomy Specimens of Patients With Lynch Syndrome.

artículo científico publicado en 2016

Performance of Lynch syndrome predictive models in quantifying the likelihood of germline mutations in patients with abnormal MLH1 immunoexpression

artículo científico publicado en 2016

Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts

artículo científico publicado en 2018

Polyunsaturated fatty acids and prostate cancer risk: a Mendelian randomisation analysis from the PRACTICAL consortium

artículo científico publicado en 2016

Ponatinib induces a sustained deep molecular response in a chronic myeloid leukaemia patient with an early relapse with a T315I mutation following allogeneic hematopoietic stem cell transplantation: a case report

Portuguese c.156_157insAlu BRCA2 founder mutation: gastrointestinal and tongue neoplasias may be part of the phenotype.

artículo científico publicado en 2012

Potential clinical applications of circulating cell-free DNA in ovarian cancer patients

artículo científico publicado en 2018

Potential downstream target genes of aberrant ETS transcription factors are differentially affected in Ewing's sarcoma and prostate carcinoma.

artículo científico publicado en 2012

Prediction of Breast and Prostate Cancer Risks in Male BRCA1 and BRCA2 Mutation Carriers Using Polygenic Risk Scores

artículo científico publicado en 2017

Prediction of individual genetic risk to prostate cancer using a polygenic score

artículo científico publicado en 2015

Promoter methylation and large intragenic rearrangements of DPYD are not implicated in severe toxicity to 5-fluorouracil-based chemotherapy in gastrointestinal cancer patients

artículo científico publicado en 2010

Prostate cancer risk regions at 8q24 and 17q24 are differentially associated with somatic TMPRSS2:ERG fusion status

artículo científico publicado en 2016

Prostate-specific antigen velocity in a prospective prostate cancer screening study of men with genetic predisposition

artículo científico publicado en 2018

Prostate-specific antigen velocity in a prospective prostate cancer screening study of men with genetic predisposition.

artículo científico publicado en 2018

Pubertal development and prostate cancer risk: Mendelian randomization study in a population-based cohort

artículo científico publicado en 2016

Publisher Correction: Shared heritability and functional enrichment across six solid cancers

scientific article published on 23 September 2019

Quantitative RARbeta2 hypermethylation: a promising prostate cancer marker

artículo científico publicado en 2004

Quantitative hypermethylation of a small panel of genes augments the diagnostic accuracy in fine-needle aspirate washings of breast lesions

article

Quantitative promoter methylation analysis of multiple cancer-related genes in renal cell tumors

artículo científico publicado en 2007

Re: Role of the oxidative DNA damage repair gene OGG1 in colorectal tumorigenesis

artículo científico publicado en 2014

Recurrent Coding Sequence Variation Explains Only A Small Fraction of the Genetic Architecture of Colorectal Cancer ⬇️

artículo científico publicado en 2015

Relative 8q gain predicts disease-specific survival irrespective of the TMPRSS2-ERG fusion status in diagnostic biopsies of prostate cancer.

artículo científico publicado en 2011

Relative copy number gain of MYC in diagnostic needle biopsies is an independent prognostic factor for prostate cancer patients

artículo científico publicado en 2006

Reply to AnnaMaria Cianciulli, Roberta Merola and Costantino Leonardo’s Letter to the Editor re: Franclim R. Ribeiro, Rui Henrique, Ana T. Martins, Carmen Jerónimo and Manuel R. Teixeira. Relative Copy Number Gain of MYC in Diagnostic Needle Biops

SEPT2 is a new fusion partner of MLL in acute myeloid leukemia with t(2;11)(q37;q23).

artículo científico publicado en 2006

SMARCB1/INI1 tumor suppressor gene is frequently inactivated in epithelioid sarcomas

artículo científico publicado en 2005

SNP interaction pattern identifier (SIPI): an intensive search for SNP-SNP interaction patterns

artículo científico publicado en 2017

Screening and characterization of BRCA2 c.156_157insAlu in Brazil: Results from 1380 individuals from the South and Southeast

scientific article published on 06 October 2018

Shared heritability and functional enrichment across six solid cancers

artículo científico publicado en 2019

Shared heritability and functional enrichment across six solid cancers

Specific and redundant activities of ETV1 and ETV4 in prostate cancer aggressiveness revealed by co-overexpression cellular contexts

artículo científico publicado en 2015

Statistical dissection of genetic pathways involved in prostate carcinogenesis

artículo científico publicado en 2006

Structural and expression changes of septins in myeloid neoplasia

artículo científico publicado en 2009

TCF21 and PCDH17 methylation: An innovative panel of biomarkers for a simultaneous detection of urological cancers

artículo científico publicado en 2011

TMPRSS2-ERG gene fusion causing ERG overexpression precedes chromosome copy number changes in prostate carcinomas and paired HGPIN lesions

artículo científico publicado en 2006

TP53 germline mutations in Portugal and genetic modifiers of age at cancer onset

artículo científico publicado en 2009

TP53mutations are associated with a particular pattern of genomic imbalances in breast carcinomas

artículo científico publicado en 2005

Target gene mutational pattern in Lynch syndrome colorectal carcinomas according to tumour location and germline mutation

artículo científico publicado en 2015

Targeted next generation sequencing identifies functionally deleterious germline mutations in novel genes in early-onset/familial prostate cancer.

artículo científico publicado en 2018

Targeted prostate cancer screening in BRCA1 and BRCA2 mutation carriers: results from the initial screening round of the IMPACT study

artículo científico publicado en 2014

Telomerase activity and genetic alterations in primary breast carcinomas

artículo científico publicado en 2003

The Brazilian Founder MutationTP53p.R337H is Uncommon in Portuguese Women Diagnosed with Breast Cancer

artículo científico publicado en 2014

The CHEK2 Variant C.349A>G Is Associated with Prostate Cancer Risk and Carriers Share a Common Ancestor

artículo científico publicado en 2020

The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer

scientific article published on 01 November 2019

The MLL recombinome of acute leukemias in 2013.

artículo científico publicado en 2013

The MSH2 c.388_389del mutation shows a founder effect in Portuguese Lynch syndrome families

artículo científico publicado en 2012

The Spectrum of FANCM Protein Truncating Variants in European Breast Cancer Cases

scientific article published on 26 January 2020

The c.156_157insAlu BRCA2 rearrangement accounts for more than one-fourth of deleterious BRCA mutations in northern/central Portugal.

artículo científico publicado en 2008

The effects of height and BMI on prostate cancer incidence and mortality: a Mendelian randomization study in 20,848 cases and 20,214 controls from the PRACTICAL consortium

artículo científico publicado en 2015

The loss of NKX3.1 expression in testicular--and prostate--cancers is not caused by promoter hypermethylation

artículo científico publicado en 2005

The nonsense mutation MSH2 c.2152C>T shows a founder effect in Portuguese Lynch syndrome families

artículo científico publicado en 2019

The order of genetic events associated with colorectal cancer progression inferred from meta-analysis of copy number changes

artículo científico publicado en 2006

The role of TP53 pathogenic variants in early-onset HER2-positive breast cancer

artículo científico publicado en 2020

The role of germline mutations in the BRCA1/2 and mismatch repair genes in men ascertained for early-onset and/or familial prostate cancer

artículo científico publicado en 2015

The role of targeted BRCA1/BRCA2 mutation analysis in hereditary breast/ovarian cancer families of Portuguese ancestry

artículo científico publicado en 2014

Three epigenetic biomarkers, GDF15, TMEFF2, and VIM, accurately predict bladder cancer from DNA-based analyses of urine samples

artículo científico publicado en 2010

Transcriptome instability as a molecular pan-cancer characteristic of carcinomas

artículo científico publicado en 2014

Transcriptome-wide association study of breast cancer risk by estrogen-receptor status

artículo científico publicado en 2020

Translocation (3;3)(p14;q29) as the Primary Chromosome Abnormality in a Peritoneal Mesothelioma

scientific article published on 01 May 1998

Truncating and missense PPM1D mutations in early-onset and/or familial/hereditary prostate cancer patients.

artículo científico publicado en 2016

Tumors of the Breast

Tumors of the Male Genital Organs

Uncovering potential downstream targets of oncogenic GRPR overexpression in prostate carcinomas harboring ETS rearrangements.

artículo científico publicado en 2015

Validation of a Next-Generation Sequencing Pipeline for the Molecular Diagnosis of Multiple Inherited Cancer Predisposing Syndromes

artículo científico publicado en 2017

Variability of the paracrine-induced osteoclastogenesis by human breast cancer cell lines.

artículo científico publicado en 2012

Widening the spectrum of Lynch syndrome: first report of testicular seminoma attributable to MSH2 loss

scientific article published on 13 November 2019

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