Lista de obras - Jeffrey D. Rudolf - Dominio Público Uruguay

A Mutasynthetic Library of Platensimycin and Platencin Analogues

artículo científico publicado en 2016

A genetically amenable platensimycin- and platencin-overproducer as a platform for biosynthetic explorations: a showcase of PtmO4, a long-chain acyl-CoA dehydrogenase.

artículo científico

Angucyclines and Angucyclinones from Streptomyces sp. CB01913 Featuring C-Ring Cleavage and Expansion ⬇️

artículo científico publicado en 2015

Antibacterial sulfur-containing platensimycin and platencin congeners from Streptomyces platensis SB12029. ⬇️

artículo científico publicado en 2016

Bacterial terpenome

artículo científico publicado en 2020

Biochemical and Structural Characterization of TtnD, a Prenylated FMN-Dependent Decarboxylase from the Tautomycetin Biosynthetic Pathway

scientific article published on 10 September 2018

Biosynthesis of thiocarboxylic acid-containing natural products. ⬇️

artículo científico publicado en 2018

Biosynthetic Origin of the Ether Ring in Platensimycin.

artículo científico publicado en 2016

Biosynthetic potential-based strain prioritization for natural product discovery: a showcase for diterpenoid-producing actinomycetes

artículo científico publicado en 2014

BlmB and TlmB provide resistance to the bleomycin family of antitumor antibiotics by N-acetylating metal-free bleomycin, tallysomycin, phleomycin, and zorbamycin

artículo científico publicado en 2014

Characterization and Crystal Structure of a Nonheme Diiron Monooxygenase Involved in Platensimycin and Platencin Biosynthesis

scientific article published on 23 July 2019

Correction to multisite prenylation of 4-substituted tryptophans by dimethylallyltryptophan synthase

artículo científico publicado en 2013

Cryptic and Stereospecific Hydroxylation, Oxidation, and Reduction in Platensimycin and Platencin Biosynthesis.

artículo científico publicado en 2019

Crystal Structure of Thioesterase SgcE10 Supporting Common Polyene Intermediates in 9- and 10-Membered Enediyne Core Biosynthesis

artículo científico publicado en 2017

Crystal Structure of the Zorbamycin-Binding Protein ZbmA, the Primary Self-Resistance Element in Streptomyces flavoviridis ATCC21892

artículo científico publicado en 2015

Crystal Structures of SgcE6 and SgcC, the Two-Component Monooxygenase That Catalyzes Hydroxylation of a Carrier Protein-Tethered Substrate during the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 in Streptomyces globisporus.

artículo científico publicado en 2016

Crystal structure of SgcJ, an NTF2-like superfamily protein involved in biosynthesis of the nine-membered enediyne antitumor antibiotic C-1027

artículo científico publicado en 2016

Cytochrome P450-Catalyzed Hydroxylation Initiating Ether Formation in Platensimycin Biosynthesis

artículo científico publicado en 2018

Cytochromes P450 for natural product biosynthesis in Streptomyces: sequence, structure, and function.

artículo científico

Discovery and Biosynthesis of a Structurally Dynamic Antibacterial Diterpenoid ⬇️

Discovery of the Tiancilactone Antibiotics by Genome Mining of Atypical Bacterial Type II Diterpene Synthases ⬇️

scientific article published on 27 May 2018

Discovery, Structure, and Mechanism of a Class II Sesquiterpene Cyclase

artículo científico publicado en 2022

Divergent synthesis of complex diterpenes through a hybrid oxidative approach

artículo científico publicado en 2020

Enediyne polyketide synthases stereoselectively reduce the β-ketoacyl intermediates to β-D-hydroxyacyl intermediates in enediyne core biosynthesis

artículo científico publicado en 2014

Enediynes: Exploration of microbial genomics to discover new anticancer drug leads.

artículo científico publicado en 2014

Evaluation of Platensimycin and Platensimycin-Inspired Thioether Analogues against Methicillin-Resistant Staphylococcus aureus in Topical and Systemic Infection Mouse Models

artículo científico publicado en 2019

Genome neighborhood network reveals insights into enediyne biosynthesis and facilitates prediction and prioritization for discovery

artículo científico publicado en 2015

Germicidins H-J from Streptomyces sp. CB00361. ⬇️

artículo científico publicado en 2016

In vivo instability of platensimycin and platencin: Synthesis and biological evaluation of urea- and carbamate-platensimycin

artículo científico publicado en 2017

Mechanisms of self-resistance in the platensimycin- and platencin-producing Streptomyces platensis MA7327 and MA7339 strains.

artículo científico publicado en 2014

Natural separation of the acyl-CoA ligase reaction results in a non-adenylating enzyme

artículo científico publicado en 2018

Nutritional control of antibiotic production by Streptomyces platensis MA7327: importance of l-aspartic acid. ⬇️

artículo científico

P450-Catalyzed Tailoring Steps in Leinamycin Biosynthesis Featuring Regio- and Stereoselective Hydroxylations and Substrate Promiscuities

artículo científico publicado en 2018

Platensimycin and platencin: Inspirations for chemistry, biology, enzymology, and medicine

artículo científico publicado en 2016

Resistance to Enediyne Antitumor Antibiotics by Sequestration

artículo científico publicado en 2018

Strain Prioritization and Genome Mining for Enediyne Natural Products

artículo científico publicado en 2016

Strain prioritization for natural product discovery by a high-throughput real-time PCR method.

artículo científico publicado en 2014

Structural Insights into the Free-Standing Condensation Enzyme SgcC5 Catalyzing Ester-Bond Formation in the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027.

artículo científico publicado en 2018

Structure of the ent-Copalyl Diphosphate Synthase PtmT2 from Streptomyces platensis CB00739, a Bacterial Type II Diterpene Synthase.

artículo científico publicado en 2016

Terpene synthases in disguise: enzymology, structure, and opportunities of non-canonical terpene synthases

scientific article published on 01 March 2020

The Natural Products Atlas 2.0: a database of microbially-derived natural products

artículo científico

Tyrosine O-prenyltransferase SirD catalyzes S-, C-, and N-prenylations on tyrosine and tryptophan derivatives

artículo científico publicado en 2013

Lista de obras de Jeffrey D. Rudolf

A Mutasynthetic Library of Platensimycin and Platencin Analogues

A genetically amenable platensimycin- and platencin-overproducer as a platform for biosynthetic explorations: a showcase of PtmO4, a long-chain acyl-CoA dehydrogenase.

Angucyclines and Angucyclinones from Streptomyces sp. CB01913 Featuring C-Ring Cleavage and Expansion ⬇️

Antibacterial sulfur-containing platensimycin and platencin congeners from Streptomyces platensis SB12029. ⬇️

Bacterial terpenome

Biochemical and Structural Characterization of TtnD, a Prenylated FMN-Dependent Decarboxylase from the Tautomycetin Biosynthetic Pathway

Biosynthesis of thiocarboxylic acid-containing natural products. ⬇️

Biosynthetic Origin of the Ether Ring in Platensimycin.

Biosynthetic potential-based strain prioritization for natural product discovery: a showcase for diterpenoid-producing actinomycetes

BlmB and TlmB provide resistance to the bleomycin family of antitumor antibiotics by N-acetylating metal-free bleomycin, tallysomycin, phleomycin, and zorbamycin

Characterization and Crystal Structure of a Nonheme Diiron Monooxygenase Involved in Platensimycin and Platencin Biosynthesis

Correction to multisite prenylation of 4-substituted tryptophans by dimethylallyltryptophan synthase

Cryptic and Stereospecific Hydroxylation, Oxidation, and Reduction in Platensimycin and Platencin Biosynthesis.

Crystal Structure of Thioesterase SgcE10 Supporting Common Polyene Intermediates in 9- and 10-Membered Enediyne Core Biosynthesis

Crystal Structure of the Zorbamycin-Binding Protein ZbmA, the Primary Self-Resistance Element in Streptomyces flavoviridis ATCC21892

Crystal Structures of SgcE6 and SgcC, the Two-Component Monooxygenase That Catalyzes Hydroxylation of a Carrier Protein-Tethered Substrate during the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 in Streptomyces globisporus.

Crystal structure of SgcJ, an NTF2-like superfamily protein involved in biosynthesis of the nine-membered enediyne antitumor antibiotic C-1027

Cytochrome P450-Catalyzed Hydroxylation Initiating Ether Formation in Platensimycin Biosynthesis

Cytochromes P450 for natural product biosynthesis in Streptomyces: sequence, structure, and function.

Discovery and Biosynthesis of a Structurally Dynamic Antibacterial Diterpenoid ⬇️

Discovery of the Tiancilactone Antibiotics by Genome Mining of Atypical Bacterial Type II Diterpene Synthases ⬇️

Discovery, Structure, and Mechanism of a Class II Sesquiterpene Cyclase

Divergent synthesis of complex diterpenes through a hybrid oxidative approach

Enediyne polyketide synthases stereoselectively reduce the β-ketoacyl intermediates to β-D-hydroxyacyl intermediates in enediyne core biosynthesis

Enediynes: Exploration of microbial genomics to discover new anticancer drug leads.

Evaluation of Platensimycin and Platensimycin-Inspired Thioether Analogues against Methicillin-Resistant Staphylococcus aureus in Topical and Systemic Infection Mouse Models

Genome neighborhood network reveals insights into enediyne biosynthesis and facilitates prediction and prioritization for discovery

Germicidins H-J from Streptomyces sp. CB00361. ⬇️

In vivo instability of platensimycin and platencin: Synthesis and biological evaluation of urea- and carbamate-platensimycin

Mechanisms of self-resistance in the platensimycin- and platencin-producing Streptomyces platensis MA7327 and MA7339 strains.

Natural separation of the acyl-CoA ligase reaction results in a non-adenylating enzyme

Nutritional control of antibiotic production by Streptomyces platensis MA7327: importance of l-aspartic acid. ⬇️

P450-Catalyzed Tailoring Steps in Leinamycin Biosynthesis Featuring Regio- and Stereoselective Hydroxylations and Substrate Promiscuities

Platensimycin and platencin: Inspirations for chemistry, biology, enzymology, and medicine

Resistance to Enediyne Antitumor Antibiotics by Sequestration

Strain Prioritization and Genome Mining for Enediyne Natural Products

Strain prioritization for natural product discovery by a high-throughput real-time PCR method.

Structural Insights into the Free-Standing Condensation Enzyme SgcC5 Catalyzing Ester-Bond Formation in the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027.

Structure of the ent-Copalyl Diphosphate Synthase PtmT2 from Streptomyces platensis CB00739, a Bacterial Type II Diterpene Synthase.

Terpene synthases in disguise: enzymology, structure, and opportunities of non-canonical terpene synthases

The Natural Products Atlas 2.0: a database of microbially-derived natural products

Tyrosine O-prenyltransferase SirD catalyzes S-, C-, and N-prenylations on tyrosine and tryptophan derivatives