Lista de obras - Axel Behrens - Dominio Público Uruguay

6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 is essential for p53-null cancer cells.

artículo científico publicado en 2017

A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development

artículo científico publicado en 2017

ATM signalling and cancer

artículo científico publicado en 2013

ATMIN defines an NBS1-independent pathway of ATM signalling

artículo científico publicado en 2007

ATMIN is required for maintenance of genomic stability and suppression of B cell lymphoma

artículo científico publicado en 2011

Absence of the prion protein homologue Doppel causes male sterility

artículo científico publicado en 2002

Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation

artículo científico publicado en 1999

Antigen retrieval and clearing for whole-organ immunofluorescence by FLASH

artículo científico publicado en 2020

Arginine methylation of the c-Jun coactivator RACO-1 is required for c-Jun/AP-1 activation

artículo científico publicado en 2013

Arginine methylation: Making its mark on AP-1 gene activation ⬇️

artículo científico publicado el 11 de julio de 2013

Bag1-L is a phosphorylation-dependent coactivator of c-Jun during neuronal apoptosis

artículo científico publicado en 2010

CD9 identifies pancreatic cancer stem cells and modulates glutamine metabolism to fuel tumour growth

scientific article published on 04 November 2019

Cep55 promotes cytokinesis of neural progenitors but is dispensable for most mammalian cell divisions

scientific article published on 08 April 2020

Competition between NBS1 and ATMIN controls ATM signaling pathway choice

artículo científico publicado en 2012

Creating a "Transcampus" in diabetes research between King's College London and the Technische Universität Dresden: update on islet biology and transplantation.

artículo científico publicado en 2014

DMAP1 is an essential regulator of ATM activity and function

artículo científico publicado en 2013

DNA Repair Cofactors ATMIN and NBS1 Are Required to Suppress T Cell Activation

artículo científico publicado en 2015

Deficient adaptation to centrosome duplication defects in neural progenitors causes microcephaly and subcortical heterotopias

artículo científico publicado en 2021

Disruption of Doppel prevents neurodegeneration in mice with extensive Prnp deletions

scholarly article

Dual regulation of Fbw7 function and oncogenic transformation by Usp28.

artículo científico publicado en 2014

Duct- and Acinar-Derived Pancreatic Ductal Adenocarcinomas Show Distinct Tumor Progression and Marker Expression.

artículo científico publicado en 2017

ERK activation causes epilepsy by stimulating NMDA receptor activity

artículo científico publicado en 2007

Erratum: Corrigendum: Replication stress links structural and numerical cancer chromosomal instability

artículo científico publicado en 2013

Erratum: RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress

scientific article published on 27 June 2016

F-box and WD repeat domain-containing 7 regulates intestinal cell lineage commitment and is a haploinsufficient tumor suppressor

artículo científico publicado en 2010

FBXW7 influences murine intestinal homeostasis and cancer, targeting Notch, Jun, and DEK for degradation

artículo científico publicado en 2011

FBXW7 mutations typically found in human cancers are distinct from null alleles and disrupt lung development

scientific journal article

Fbw7 and its counteracting forces in stem cells and cancer: Oncoproteins in the balance

artículo científico

Fbw7 controls neural stem cell differentiation and progenitor apoptosis via Notch and c-Jun

artículo científico publicado en 2010

Fbw7 repression by hes5 creates a feedback loop that modulates Notch-mediated intestinal and neural stem cell fate decisions

artículo científico publicado en 2013

Fbxw7 controls angiogenesis by regulating endothelial Notch activity

artículo científico publicado en 2012

High expression of vinculin predicts poor prognosis and distant metastasis and associates with influencing tumor-associated NK cell infiltration and epithelial-mesenchymal transition in gastric cancer

artículo científico publicado en 2021

Identification of a co-activator that links growth factor signalling to c-Jun/AP-1 activation

artículo científico publicado en 2010

Impact of genomic damage and ageing on stem cell function

artículo científico publicado en 2014

Impaired intervertebral disc formation in the absence of Jun.

artículo científico publicado en 2003

Impaired postnatal hepatocyte proliferation and liver regeneration in mice lacking c-jun in the liver

artículo científico publicado en 2002

Inactivation of the ATMIN/ATM pathway protects against glioblastoma formation

artículo científico publicado en 2016

Increased skeletal VEGF enhances beta-catenin activity and results in excessively ossified bones

artículo científico publicado en 2009

Infarct volume after transient middle cerebral artery occlusion (MCAo) can be reduced by attenuation but not by inactivation of c-Jun action

artículo científico publicado en 2007

Integrin signalling regulates YAP and TAZ to control skin homeostasis

artículo científico publicado en 2016

Interaction of phosphorylated c-Jun with TCF4 regulates intestinal cancer development

artículo científico publicado en 2005

Investigation of the atypical FBXW7 mutation spectrum in human tumours by conditional expression of a heterozygous propellor tip missense allele in the mouse intestines

artículo científico publicado en 2014

JNK signalling modulates intestinal homeostasis and tumourigenesis in mice

artículo científico publicado en 2009

JunB can substitute for Jun in mouse development and cell proliferation

scientific journal article

LUBAC determines chemotherapy resistance in squamous cell lung cancer

artículo científico publicado en 2019

Lgr6 labels a rare population of mammary gland progenitor cells that are able to originate luminal mammary tumours

artículo científico publicado en 2016

Loss of Fbw7 reprograms adult pancreatic ductal cells into α, δ, and β cells

artículo científico publicado en 2014

Neuronal c-Jun is required for successful axonal regeneration, but the effects of phosphorylation of its N-terminus are moderate.

artículo científico publicado en 2012

NuRD suppresses pluripotency gene expression to promote transcriptional heterogeneity and lineage commitment

artículo científico publicado en 2012

NuRD-mediated deacetylation of H3K27 facilitates recruitment of Polycomb Repressive Complex 2 to direct gene repression

artículo científico publicado en 2011

Paligenosis: prepare to regenerate!

scientific article published on 22 March 2018

Peripheral facial nerve axotomy in mice causes sprouting of motor axons into perineuronal central white matter: time course and molecular characterization

artículo científico publicado en 2010

Perturbed hematopoiesis in mice lacking ATMIN.

artículo científico publicado en 2016

Physiological and pathological functions of the prion protein homologue Dpl ⬇️

artículo científico publicado el 1 de enero de 2003

Proteasomal degradation of the tumour suppressor FBW7 requires branched ubiquitylation by TRIP12

artículo científico publicado en 2021

RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress.

artículo científico publicado en 2015

Replication stress links structural and numerical cancer chromosomal instability

artículo científico publicado en 2013

Role of the AP-1 transcription factor c-Jun in developing, adult and injured brain

artículo científico publicado en 2006

Small is not beautiful: antagonizing functions for the prion protein PrP(C) and its homologue Dpl.

artículo científico publicado en 2002

Specific pathophysiological functions of JNK isoforms in the brain

artículo científico publicado en 2005

Stem cell and progenitor fate in the mammalian intestine: Notch and lateral inhibition in homeostasis and disease

artículo científico

The AP-1 transcription factor c-Jun is required for efficient axonal regeneration

scientific journal article

The ATM cofactor ATMIN protects against oxidative stress and accumulation of DNA damage in the aging brain

artículo científico publicado en 2010

The E3 ubiquitin ligase Trim7 mediates c-Jun/AP-1 activation by Ras signalling

artículo científico publicado en 2015

The F-box protein Fbw7 is required for cerebellar development

artículo científico publicado en 2011

The GATA2 transcriptional network is requisite for RAS oncogene-driven non-small cell lung cancer

artículo científico publicado en 2012

The deubiquitinase USP28 controls intestinal homeostasis and promotes colorectal cancer

artículo científico publicado en 2014

The ubiquitin ligase SCFFbw7 antagonizes apoptotic JNK signaling

artículo científico publicado en 2004

UBR5-mediated ubiquitination of ATMIN is required for ionizing radiation-induced ATM signaling and function

artículo científico publicado en 2014

USP25 promotes pathological HIF-1-driven metabolic reprogramming and is a potential therapeutic target in pancreatic cancer

artículo científico publicado en 2022

Usp28 counteracts Fbw7 in intestinal homeostasis and cancer

artículo científico publicado en 2015

Vanilloid receptor-1 regulates neurogenic inflammation in colon and protects mice from colon cancer

artículo científico publicado en 2012

YAP1 and TAZ Control Pancreatic Cancer Initiation in Mice by Direct Up-regulation of JAK-STAT3 Signaling

artículo científico publicado en 2016

c-Jun N-Terminal Phosphorylation: Biomarker for Cellular Stress Rather than Cell Death in the Injured Cochlea.

artículo científico publicado en 2016

c-Jun N-terminal phosphorylation antagonises recruitment of the Mbd3/NuRD repressor complex

artículo científico publicado en 2011

c-Jun in Schwann cells promotes axonal regeneration and motoneuron survival via paracrine signaling.

artículo científico publicado en 2012

c-Jun is a negative regulator of myelination.

artículo científico publicado en 2008

c-Jun reprograms Schwann cells of injured nerves to generate a repair cell essential for regeneration

artículo científico publicado en 2012

Lista de obras de Axel Behrens

6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 is essential for p53-null cancer cells.

A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development

ATM signalling and cancer

ATMIN defines an NBS1-independent pathway of ATM signalling

ATMIN is required for maintenance of genomic stability and suppression of B cell lymphoma

Absence of the prion protein homologue Doppel causes male sterility

Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation

Antigen retrieval and clearing for whole-organ immunofluorescence by FLASH

Arginine methylation of the c-Jun coactivator RACO-1 is required for c-Jun/AP-1 activation

Arginine methylation: Making its mark on AP-1 gene activation ⬇️

Bag1-L is a phosphorylation-dependent coactivator of c-Jun during neuronal apoptosis

CD9 identifies pancreatic cancer stem cells and modulates glutamine metabolism to fuel tumour growth

Cep55 promotes cytokinesis of neural progenitors but is dispensable for most mammalian cell divisions

Competition between NBS1 and ATMIN controls ATM signaling pathway choice

Creating a "Transcampus" in diabetes research between King's College London and the Technische Universität Dresden: update on islet biology and transplantation.

DMAP1 is an essential regulator of ATM activity and function

DNA Repair Cofactors ATMIN and NBS1 Are Required to Suppress T Cell Activation

Deficient adaptation to centrosome duplication defects in neural progenitors causes microcephaly and subcortical heterotopias

Disruption of Doppel prevents neurodegeneration in mice with extensive Prnp deletions

Dual regulation of Fbw7 function and oncogenic transformation by Usp28.

Duct- and Acinar-Derived Pancreatic Ductal Adenocarcinomas Show Distinct Tumor Progression and Marker Expression.

ERK activation causes epilepsy by stimulating NMDA receptor activity

Erratum: Corrigendum: Replication stress links structural and numerical cancer chromosomal instability

Erratum: RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress

F-box and WD repeat domain-containing 7 regulates intestinal cell lineage commitment and is a haploinsufficient tumor suppressor

FBXW7 influences murine intestinal homeostasis and cancer, targeting Notch, Jun, and DEK for degradation

FBXW7 mutations typically found in human cancers are distinct from null alleles and disrupt lung development

Fbw7 and its counteracting forces in stem cells and cancer: Oncoproteins in the balance

Fbw7 controls neural stem cell differentiation and progenitor apoptosis via Notch and c-Jun

Fbw7 repression by hes5 creates a feedback loop that modulates Notch-mediated intestinal and neural stem cell fate decisions

Fbxw7 controls angiogenesis by regulating endothelial Notch activity

High expression of vinculin predicts poor prognosis and distant metastasis and associates with influencing tumor-associated NK cell infiltration and epithelial-mesenchymal transition in gastric cancer

Identification of a co-activator that links growth factor signalling to c-Jun/AP-1 activation

Impact of genomic damage and ageing on stem cell function

Impaired intervertebral disc formation in the absence of Jun.

Impaired postnatal hepatocyte proliferation and liver regeneration in mice lacking c-jun in the liver

Inactivation of the ATMIN/ATM pathway protects against glioblastoma formation

Increased skeletal VEGF enhances beta-catenin activity and results in excessively ossified bones

Infarct volume after transient middle cerebral artery occlusion (MCAo) can be reduced by attenuation but not by inactivation of c-Jun action

Integrin signalling regulates YAP and TAZ to control skin homeostasis

Interaction of phosphorylated c-Jun with TCF4 regulates intestinal cancer development

Investigation of the atypical FBXW7 mutation spectrum in human tumours by conditional expression of a heterozygous propellor tip missense allele in the mouse intestines

JNK signalling modulates intestinal homeostasis and tumourigenesis in mice

JunB can substitute for Jun in mouse development and cell proliferation

LUBAC determines chemotherapy resistance in squamous cell lung cancer

Lgr6 labels a rare population of mammary gland progenitor cells that are able to originate luminal mammary tumours

Loss of Fbw7 reprograms adult pancreatic ductal cells into α, δ, and β cells

Neuronal c-Jun is required for successful axonal regeneration, but the effects of phosphorylation of its N-terminus are moderate.

NuRD suppresses pluripotency gene expression to promote transcriptional heterogeneity and lineage commitment

NuRD-mediated deacetylation of H3K27 facilitates recruitment of Polycomb Repressive Complex 2 to direct gene repression

Paligenosis: prepare to regenerate!

Peripheral facial nerve axotomy in mice causes sprouting of motor axons into perineuronal central white matter: time course and molecular characterization

Perturbed hematopoiesis in mice lacking ATMIN.

Physiological and pathological functions of the prion protein homologue Dpl ⬇️

Proteasomal degradation of the tumour suppressor FBW7 requires branched ubiquitylation by TRIP12

RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress.

Replication stress links structural and numerical cancer chromosomal instability

Role of the AP-1 transcription factor c-Jun in developing, adult and injured brain

Small is not beautiful: antagonizing functions for the prion protein PrP(C) and its homologue Dpl.

Specific pathophysiological functions of JNK isoforms in the brain

Stem cell and progenitor fate in the mammalian intestine: Notch and lateral inhibition in homeostasis and disease

The AP-1 transcription factor c-Jun is required for efficient axonal regeneration

The ATM cofactor ATMIN protects against oxidative stress and accumulation of DNA damage in the aging brain

The E3 ubiquitin ligase Trim7 mediates c-Jun/AP-1 activation by Ras signalling

The F-box protein Fbw7 is required for cerebellar development

The GATA2 transcriptional network is requisite for RAS oncogene-driven non-small cell lung cancer

The deubiquitinase USP28 controls intestinal homeostasis and promotes colorectal cancer

The ubiquitin ligase SCFFbw7 antagonizes apoptotic JNK signaling

UBR5-mediated ubiquitination of ATMIN is required for ionizing radiation-induced ATM signaling and function

USP25 promotes pathological HIF-1-driven metabolic reprogramming and is a potential therapeutic target in pancreatic cancer

Usp28 counteracts Fbw7 in intestinal homeostasis and cancer

Vanilloid receptor-1 regulates neurogenic inflammation in colon and protects mice from colon cancer

YAP1 and TAZ Control Pancreatic Cancer Initiation in Mice by Direct Up-regulation of JAK-STAT3 Signaling

c-Jun N-Terminal Phosphorylation: Biomarker for Cellular Stress Rather than Cell Death in the Injured Cochlea.

c-Jun N-terminal phosphorylation antagonises recruitment of the Mbd3/NuRD repressor complex

c-Jun in Schwann cells promotes axonal regeneration and motoneuron survival via paracrine signaling.

c-Jun is a negative regulator of myelination.

c-Jun reprograms Schwann cells of injured nerves to generate a repair cell essential for regeneration