Lista de obras - Laura Ferraiuolo - Dominio Público Uruguay

<i>C9ORF72</i>-derived poly-GA DPRs undergo endocytic uptake in iAstrocytes and spread to motor neurons

artículo científico publicado en 2022

Additive amelioration of ALS by co-targeting independent pathogenic mechanisms

scientific article published on 11 January 2017

Applications of machine learning to diagnosis and treatment of neurodegenerative diseases

artículo científico publicado en 2020

Astrocyte adenosine deaminase loss increases motor neuron toxicity in amyotrophic lateral sclerosis

article

Can Astrocytes Be a Target for Precision Medicine?

artículo científico publicado en 2017

Delayed disease onset and extended survival in the SOD1G93A rat model of amyotrophic lateral sclerosis after suppression of mutant SOD1 in the motor cortex

artículo científico publicado en 2014

Differences in protein quality control correlate with phenotype variability in 2 mouse models of familial amyotrophic lateral sclerosis.

artículo científico publicado en 2014

Direct conversion of patient fibroblasts demonstrates non-cell autonomous toxicity of astrocytes to motor neurons in familial and sporadic ALS

artículo científico publicado en 2013

Directly converted astrocytes retain the ageing features of the donor fibroblasts and elucidate the astrocytic contribution to human CNS health and disease

artículo científico publicado en 2020

Dysregulation of astrocyte-motoneuron cross-talk in mutant superoxide dismutase 1-related amyotrophic lateral sclerosis

artículo científico publicado en 2011

Gene delivery improvement for treating the lysosomal storage disorder metachromatic leukodystrophy

artículo científico publicado en 2012

Gene expression profiling in human neurodegenerative disease

artículo científico publicado en 2012

High content analysis in amyotrophic lateral sclerosis

artículo científico publicado en 2016

Improving single injection CSF delivery of AAV9-mediated gene therapy for SMA: a dose-response study in mice and nonhuman primates

artículo científico publicado en 2014

Loss of nuclear TDP-43 in amyotrophic lateral sclerosis (ALS) causes altered expression of splicing machinery and widespread dysregulation of RNA splicing in motor neurones.

artículo científico publicado en 2014

Lysosomal and phagocytic activity is increased in astrocytes during disease progression in the SOD1 (G93A) mouse model of amyotrophic lateral sclerosis

artículo científico publicado en 2015

Major histocompatibility complex class I molecules protect motor neurons from astrocyte-induced toxicity in amyotrophic lateral sclerosis

artículo científico publicado en 2016

Micro-RNAs secreted through astrocyte-derived extracellular vesicles cause neuronal network degeneration in C9orf72 ALS

artículo científico publicado en 2019

MicroNeurotrophins Improve Survival in Motor Neuron-Astrocyte Co-Cultures but Do Not Improve Disease Phenotypes in a Mutant SOD1 Mouse Model of Amyotrophic Lateral Sclerosis

artículo científico publicado en 2016

Microarray analysis of the cellular pathways involved in the adaptation to and progression of motor neuron injury in the SOD1 G93A mouse model of familial ALS.

artículo científico publicado en 2007

Microglia induce motor neuron death via the classical NF-κB pathway in amyotrophic lateral sclerosis

artículo científico publicado en 2014

Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis ⬇️

artículo científico publicado el 1 de noviembre de 2011

Mutations in CHMP2B in lower motor neuron predominant amyotrophic lateral sclerosis (ALS).

artículo científico publicado en 2010

Neural stem cells as a therapeutic approach for amyotrophic lateral sclerosis

artículo científico publicado en 2013

New In Vitro Models to Study Amyotrophic Lateral Sclerosis

artículo científico publicado en 2016

OUP accepted manuscript

article by Laura Ferraiuolo & Pamela J. Shaw published 2018 in Brain

Oligodendrocytes contribute to motor neuron death in ALS via SOD1-dependent mechanism

artículo científico publicado en 2016

Phosphatase and tensin homologue/protein kinase B pathway linked to motor neuron survival in human superoxide dismutase 1-related amyotrophic lateral sclerosis

artículo científico publicado en 2011

SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits

artículo científico publicado en 2017

The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy

artículo científico publicado en 2016

The non-cell-autonomous component of ALS: new in vitro models and future challenges.

artículo científico publicado en 2014

Therapeutic AAV9-mediated suppression of mutant SOD1 slows disease progression and extends survival in models of inherited ALS

artículo científico publicado en 2013

Transcriptional response of the neuromuscular system to exercise training and potential implications for ALS

artículo científico publicado en 2009

Transcriptomic indices of fast and slow disease progression in two mouse models of amyotrophic lateral sclerosis.

artículo científico publicado en 2013

Translating SOD1 Gene Silencing toward the Clinic: A Highly Efficacious, Off-Target-free, and Biomarker-Supported Strategy for fALS.

artículo científico publicado en 2018

Translational profiling identifies a cascade of damage initiated in motor neurons and spreading to glia in mutant SOD1-mediated ALS.

artículo científico publicado en 2015

Ursodeoxycholic Acid Improves Mitochondrial Function and Redistributes Drp1 in Fibroblasts from Patients with Either Sporadic or Familial Alzheimer's Disease

artículo científico publicado en 2018

Lista de obras de Laura Ferraiuolo

<i>C9ORF72</i>-derived poly-GA DPRs undergo endocytic uptake in iAstrocytes and spread to motor neurons

Additive amelioration of ALS by co-targeting independent pathogenic mechanisms

Applications of machine learning to diagnosis and treatment of neurodegenerative diseases

Astrocyte adenosine deaminase loss increases motor neuron toxicity in amyotrophic lateral sclerosis

Can Astrocytes Be a Target for Precision Medicine?

Delayed disease onset and extended survival in the SOD1G93A rat model of amyotrophic lateral sclerosis after suppression of mutant SOD1 in the motor cortex

Differences in protein quality control correlate with phenotype variability in 2 mouse models of familial amyotrophic lateral sclerosis.

Direct conversion of patient fibroblasts demonstrates non-cell autonomous toxicity of astrocytes to motor neurons in familial and sporadic ALS

Directly converted astrocytes retain the ageing features of the donor fibroblasts and elucidate the astrocytic contribution to human CNS health and disease

Dysregulation of astrocyte-motoneuron cross-talk in mutant superoxide dismutase 1-related amyotrophic lateral sclerosis

Gene delivery improvement for treating the lysosomal storage disorder metachromatic leukodystrophy

Gene expression profiling in human neurodegenerative disease

High content analysis in amyotrophic lateral sclerosis

Improving single injection CSF delivery of AAV9-mediated gene therapy for SMA: a dose-response study in mice and nonhuman primates

Loss of nuclear TDP-43 in amyotrophic lateral sclerosis (ALS) causes altered expression of splicing machinery and widespread dysregulation of RNA splicing in motor neurones.

Lysosomal and phagocytic activity is increased in astrocytes during disease progression in the SOD1 (G93A) mouse model of amyotrophic lateral sclerosis

Major histocompatibility complex class I molecules protect motor neurons from astrocyte-induced toxicity in amyotrophic lateral sclerosis

Micro-RNAs secreted through astrocyte-derived extracellular vesicles cause neuronal network degeneration in C9orf72 ALS

MicroNeurotrophins Improve Survival in Motor Neuron-Astrocyte Co-Cultures but Do Not Improve Disease Phenotypes in a Mutant SOD1 Mouse Model of Amyotrophic Lateral Sclerosis

Microarray analysis of the cellular pathways involved in the adaptation to and progression of motor neuron injury in the SOD1 G93A mouse model of familial ALS.

Microglia induce motor neuron death via the classical NF-κB pathway in amyotrophic lateral sclerosis

Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis ⬇️

Mutations in CHMP2B in lower motor neuron predominant amyotrophic lateral sclerosis (ALS).

Neural stem cells as a therapeutic approach for amyotrophic lateral sclerosis

New In Vitro Models to Study Amyotrophic Lateral Sclerosis

OUP accepted manuscript

Oligodendrocytes contribute to motor neuron death in ALS via SOD1-dependent mechanism

Phosphatase and tensin homologue/protein kinase B pathway linked to motor neuron survival in human superoxide dismutase 1-related amyotrophic lateral sclerosis

SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits

The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy

The non-cell-autonomous component of ALS: new in vitro models and future challenges.

Therapeutic AAV9-mediated suppression of mutant SOD1 slows disease progression and extends survival in models of inherited ALS

Transcriptional response of the neuromuscular system to exercise training and potential implications for ALS

Transcriptomic indices of fast and slow disease progression in two mouse models of amyotrophic lateral sclerosis.

Translating SOD1 Gene Silencing toward the Clinic: A Highly Efficacious, Off-Target-free, and Biomarker-Supported Strategy for fALS.

Translational profiling identifies a cascade of damage initiated in motor neurons and spreading to glia in mutant SOD1-mediated ALS.

Ursodeoxycholic Acid Improves Mitochondrial Function and Redistributes Drp1 in Fibroblasts from Patients with Either Sporadic or Familial Alzheimer's Disease