Filtros de búsqueda

Lista de obras de Mario Paolo Colombo

A non-redundant role for OX40 in the competitive fitness of Treg in response to IL-2

artículo científico publicado en 2010

ATP Release from Chemotherapy-Treated Dying Leukemia Cells Elicits an Immune Suppressive Effect by Increasing Regulatory T Cells and Tolerogenic Dendritic Cells.

artículo científico publicado en 2017

Accelerated dendritic-cell migration and T-cell priming in SPARC-deficient mice

artículo científico publicado en 2005

Active immunization of metastatic melanoma patients with interleukin-2-transduced allogeneic melanoma cells: evaluation of efficacy and tolerability

scientific article published on 01 June 1997

Adoptive immunotherapy of a BALB/c lymphoma by syngeneic anti-DBA/2 immune lymphoid cells: characterization of the effector population and evidence for the role of the host's non-T cells.

artículo científico publicado en 1985

Amino-biphosphonate-mediated MMP-9 inhibition breaks the tumor-bone marrow axis responsible for myeloid-derived suppressor cell expansion and macrophage infiltration in tumor stroma

artículo científico publicado en 2007

An in vivo model to compare human leukocyte infiltration in carcinoma xenografts producing different chemokines.

artículo científico publicado en 1995

An unusual BRCA2 allele carrying two splice site mutations

artículo científico publicado en 2009

Angiopoietin decoy secreted at tumor site impairs tumor growth and metastases by inducing local inflammation and altering neoangiogenesis

artículo científico publicado en 2004

Antibody-Fc/FcR Interaction on Macrophages as a Mechanism for Hyperprogressive Disease in Non-small Cell Lung Cancer Subsequent to PD-1/PD-L1 Blockade

scientific article published on 11 September 2018

Antibody-mediated blockade of JMJD6 interaction with collagen I exerts antifibrotic and antimetastatic activities.

artículo científico publicado en 2017

Apoptosis induced by HIV-gp120 in a Th1 clone involves the generation of reactive oxygen intermediates downstream CD95 triggering

artículo científico publicado en 1997

Application of multicolor fluorescence in situ hybridization analysis for detection of cross-contamination and in vitro progression in commonly used murine tumor cell lines

artículo científico publicado en 2002

Bone marrow stroma CD40 expression correlates with inflammatory mast cell infiltration and disease progression in splenic marginal zone lymphoma

artículo científico publicado en 2014

CD4 T cells inhibit in vivo the CD8-mediated immune response against murine colon carcinoma cells transduced with interleukin-12 genes

scientific article published on 01 January 1995

CD4+CD25+ regulatory T cells suppress mast cell degranulation and allergic responses through OX40-OX40L interaction.

artículo científico publicado en 2008

CD40/CD40L interaction regulates CD4+CD25+ T reg homeostasis through dendritic cell-produced IL-2.

artículo científico publicado en 2005

CD99 acts as an oncosuppressor in osteosarcoma

artículo científico publicado en 2006

CD99 drives terminal differentiation of osteosarcoma cells by acting as a spatial regulator of ERK 1/2.

artículo científico publicado en 2014

CD99 inhibits neural differentiation of human Ewing sarcoma cells and thereby contributes to oncogenesis

artículo científico publicado en 2010

CD99 triggering in Ewing sarcoma delivers a lethal signal through p53 pathway reactivation and cooperates with doxorubicin

artículo científico publicado en 2014

CD99 triggering induces methuosis of Ewing sarcoma cells through IGF-1R/RAS/Rac1 signaling

artículo científico publicado en 2016

Cancer immunotherapy based on killing of Salmonella-infected tumor cells

artículo científico publicado en 2005

Caveolin-1 reduces osteosarcoma metastases by inhibiting c-Src activity and met signaling.

artículo científico publicado en 2007

Chaperon and adjuvant activity of hsp70: different natural killer requirement for cross-priming of chaperoned and bystander antigens

artículo científico publicado en 2005

Choosing wisely first line immunotherapy in non-small cell lung cancer (NSCLC): what to add and what to leave out

artículo científico publicado en 2019

Common extracellular matrix regulation of myeloid cell activity in the bone marrow and tumor microenvironments

artículo científico publicado en 2017

Consensus nomenclature for CD8(+) T cell phenotypes in cancer

artículo científico publicado en 2015

Contrasting roles of SPARC-related granuloma in bacterial containment and in the induction of anti-Salmonella typhimurium immunity

artículo científico publicado en 2008

Convergences and divergences of thymus- and peripherally derived regulatory T cells in cancer

artículo científico publicado en 2013

Cross-Talk between Myeloid-Derived Suppressor Cells and Mast Cells Mediates Tumor-Specific Immunosuppression in Prostate Cancer

artículo científico publicado en 2018

Cross-reactions between tumor cells and allogeneic normal tissues. Inhibition of a syngeneic lymphoma outgrowth in H-2 and non-H-2 alloimmune BALB/c mice.

artículo científico publicado en 1982

Cytokine Gene Transduction in the Immunotherapy of Cancer

artículo científico publicado el 1 de enero de 1997

Cytokine gene transfer in tumor cells as an approach to antitumor therapy

artículo científico publicado el 1 de enero de 1992

Cytotoxic T lymphocyte response against non-immunoselected tumor antigens predicts the outcome of gene therapy with IL-12-transduced tumor cell vaccine.

artículo científico publicado en 1999

DNA threads released by activated CD4+ T lymphocytes provide autocrine costimulation

artículo científico publicado en 2019

Defective stromal remodeling and neutrophil extracellular traps in lymphoid tissues favor the transition from autoimmunity to lymphoma.

artículo científico publicado en 2013

Dendritic cells infiltrating tumors cotransduced with granulocyte/macrophage colony-stimulating factor (GM-CSF) and CD40 ligand genes take up and present endogenous tumor-associated antigens, and prime naive mice for a cytotoxic T lymphocyte respons

artículo científico publicado en 1999

Different requirements for alpha-galactosylceramide and recombinant IL-12 antitumor activity in the treatment of C-26 colon carcinoma hepatic metastases.

artículo científico publicado en 2001

Down-regulation of SPARC/osteonectin/BM-40 expression in methylcholanthrene-induced fibrosarcomas and in Kirsten-MSV transformed fibroblasts.

artículo científico publicado en 1991

Effect of adrenergic and Ca2+ antagonists on increased ornithine decarboxylase expression in regenerating rat liver.

artículo científico publicado en 1990

Eighth annual meeting of the Italian network for tumor biotherapy (NIBIT), Siena, October 7-9, 2010.

artículo científico publicado en 2011

Enhanced efficacy of tumor cell vaccines transfected with secretable hsp70.

artículo científico publicado en 2004

Evaluation of osteonectin as a diagnostic marker of osteogenic bone tumors

artículo científico publicado en 1992

Exacerbated experimental autoimmune encephalomyelitis in mast-cell-deficient Kit W-sh/W-sh mice.

artículo científico publicado en 2011

Expression levels of insulin receptor substrate-1 modulate the osteoblastic differentiation of mesenchymal stem cells and osteosarcoma cells

artículo científico publicado en 2014

Expression of a growth arrest specific gene (gas-1) in transformed cells ⬇️

artículo científico publicado el 1 de julio de 1992

Frontline Science: Mast cells regulate neutrophil homeostasis by influencing macrophage clearance activity

artículo científico publicado en 2019

Genetic deletion of osteopontin in TRAMP mice skews prostate carcinogenesis from adenocarcinoma to aggressive human-like neuroendocrine cancers

artículo científico publicado en 2015

Genetic modification of a carcinoma with the IL-4 gene increases the influx of dendritic cells relative to other cytokines

artículo científico publicado en 1997

Goals and objectives of the Italian Network for Tumor Biotherapy (NIBIT).

artículo científico publicado en 2017

HIV/gp120 and PMA/ionomycin induced apoptosis but not activation induced cell death require PKC for Fas-L upregulation

article

Healthy and tumoral tissue resistivity in wild-type and sparc-/- animal models.

artículo científico publicado en 2016

IL-10-producing B cells are characterized by a specific methylation signature

scientific article published on 07 May 2019

IL-15 cis presentation is required for optimal NK cell activation in lipopolysaccharide-mediated inflammatory conditions

scientific article published on 19 September 2013

Imatinib Spares cKit-Expressing Prostate Neuroendocrine Tumors, whereas Kills Seminal Vesicle Epithelial-Stromal Tumors by Targeting PDGFR-β.

artículo científico publicado en 2016

Immune Checkpoint Ligand Reverse Signaling: Looking Back to Go Forward in Cancer Therapy.

artículo científico publicado en 2019

Immunodominance in the T-cell response to multiple non-H-2 histocompatibility antigens. V. Chromosomal mapping of the immunodominant cytotoxic T-cell target-1 (CTT-1)

artículo científico publicado en 1993

Improved clinical outcome in indolent B-cell lymphoma patients vaccinated with autologous tumor cells experiencing immunogenic death.

artículo científico publicado en 2010

In Ewing's sarcoma CCN3(NOV) inhibits proliferation while promoting migration and invasion of the same cell type

artículo científico publicado en 2005

In vitro analysis of the melanoma/endothelium interaction increasing the release of soluble intercellular adhesion molecule 1 by endothelial cells

artículo científico publicado en 1999

Infiltrating mast cell-mediated stimulation of estrogen receptor activity in breast cancer cells promotes the luminal phenotype

scientific article published on 16 March 2020

Inheritance of a mutant histocompatibility gene and a new mammary tumor virus genome in the B6.KH-84 mouse strain

artículo científico publicado en 1987

Inhibiting interactions of lysine demethylase LSD1 with snail/slug blocks cancer cell invasion

artículo científico publicado en 2012

Innovative Therapy, Monoclonal Antibodies and Beyond.

artículo científico publicado en 2017

Interferon gamma-independent rejection of interleukin 12-transduced carcinoma cells requires CD4+ T cells and Granulocyte/Macrophage colony-stimulating factor

artículo científico publicado en 1998

Interleukin 12-mediated prevention of spontaneous mammary adenocarcinomas in two lines of Her-2/neu transgenic mice.

artículo científico publicado en 1998

Interleukin-12 in anti-tumor immunity and immunotherapy.

artículo científico publicado en 2002

Interleukin-12 production by leukemia-derived dendritic cells counteracts the inhibitory effect of leukemic microenvironment on T cells

article

Intratumor OX40 stimulation inhibits IRF1 expression and IL-10 production by Treg cells while enhancing CD40L expression by effector memory T cells

artículo científico publicado en 2011

Is GPNMB the Achilles' Heel of Mo-MDSC While Marking Their Suppressive Activity?

artículo científico publicado en 2018

Isolation and mapping to 17p12-13 of the human homologous of the murine growth arrest specific Gas-3 gene

artículo científico publicado en 1992

Lipopolysaccharide or Whole Bacteria Block the Conversion of Inflammatory Monocytes into Dendritic Cells In Vivo ⬇️

artículo científico publicado el 20 de octubre de 2003

Liver follicular helper T-cells predict the achievement of virological response following interferon-based treatment in HCV-infected patients

artículo científico publicado en 2012

Localization of growth arrest-specific genes on mouse chromosomes 1, 7, 8, 11, 13, and 16.

artículo científico publicado en 1992

Lymphotoxin gene expression by melanocytes and melanoma cell lines and persistence of unspliced mRNA

artículo científico publicado en 1993

MEF2C and SOCS2 in stemness regulation.

artículo científico publicado en 2015

Macrophage-derived SPARC bridges tumor cell-extracellular matrix interactions toward metastasis

artículo científico publicado en 2008

Mast Cells Control the Expansion and Differentiation of IL-10–Competent B Cells

artículo científico publicado en 2014

Mast Cells Infiltrating Inflamed or Transformed Gut Alternatively Sustain Mucosal Healing or Tumor Growth.

artículo científico publicado en 2015

Mast cell targeting hampers prostate adenocarcinoma development but promotes the occurrence of highly malignant neuroendocrine cancers

artículo científico publicado en 2011

Mast cells and Th17 cells contribute to the lymphoma-associated pro-inflammatory microenvironment of angioimmunoblastic T-cell lymphoma.

artículo científico publicado en 2010

Mast cells boost myeloid-derived suppressor cell activity and contribute to the development of tumor-favoring microenvironment.

artículo científico publicado en 2014

Mast cells counteract regulatory T-cell suppression through interleukin-6 and OX40/OX40L axis toward Th17-cell differentiation

artículo científico publicado en 2009

Mast cells in the pathogenesis of multiple sclerosis and experimental autoimmune encephalomyelitis

artículo científico publicado en 2012

Matricellular proteins at the crossroad of inflammation and cancer.

artículo científico publicado en 2008

Matricellular proteins tune myeloid-derived suppressor cell recruitment and function in breast cancer

artículo científico publicado en 2017

Matricellular proteins: from homeostasis to inflammation, cancer, and metastasis

artículo científico publicado en 2010

Mesenchymal Transition of High-Grade Breast Carcinomas Depends on Extracellular Matrix Control of Myeloid Suppressor Cell Activity

artículo científico publicado en 2016

Microenvironment-centred dynamics in aggressive B-cell lymphomas

artículo científico publicado en 2012

Modulation of FcεRI-dependent mast cell response by OX40L via Fyn, PI3K, and RhoA.

artículo científico publicado en 2012

Modulation of peripheral blood immune cells by early use of steroids and its association with clinical outcomes in patients with metastatic non-small cell lung cancer treated with immune checkpoint inhibitors

artículo científico publicado en 2019

Modulation of tryptophan catabolism by human leukemic cells results in the conversion of CD25- into CD25+ T regulatory cells

artículo científico publicado en 2007

Molecular mechanisms of CD99-induced caspase-independent cell death and cell-cell adhesion in Ewing's sarcoma cells: actin and zyxin as key intracellular mediators.

artículo científico publicado en 2004

Murine dendritic cells loaded in vitro with soluble protein prime cytotoxic T lymphocytes against tumor antigen in vivo

artículo científico publicado en 1996

Myeloid cell expansion elicited by the progression of spontaneous mammary carcinomas in c-erbB-2 transgenic BALB/c mice suppresses immune reactivity

artículo científico publicado en 2003

Neoplastic and stromal cells contribute to an extracellular matrix gene expression profile defining a breast cancer subtype likely to progress

artículo científico publicado en 2013

Neutrophil extracellular traps mediate transfer of cytoplasmic neutrophil antigens to myeloid dendritic cells toward ANCA induction and associated autoimmunity

artículo científico publicado en 2012

Nicotinamide Phosphoribosyltransferase Acts as a Metabolic Gate for Mobilization of Myeloid-Derived Suppressor Cells

scientific article published on 18 February 2019

Ninth annual meeting of the Italian Network for Tumor Biotherapy (NIBIT), Siena, Italy, October 19-22, 2011: New perspectives in the immunotherapy of cancer

artículo científico publicado en 2012

Nitroaspirin corrects immune dysfunction in tumor-bearing hosts and promotes tumor eradication by cancer vaccination

artículo científico publicado en 2005

Nonredundant roles of antibody, cytokines, and perforin in the eradication of established Her-2/neu carcinomas

artículo científico publicado en 2003

Nucleofection is an efficient nonviral transfection technique for human bone marrow-derived mesenchymal stem cells

artículo científico publicado en 2005

OX40 triggering blocks suppression by regulatory T cells and facilitates tumor rejection

OX40 triggering concomitant to IL12-engineered cell vaccine hampers the immunoprevention of HER2/neu-driven mammary carcinogenesis

scientific article published on 11 June 2018

On OX40 and PD-1 Combination: Why Should OX40 Be First in Sequence?

artículo científico publicado en 2017

Oncogene-driven intrinsic inflammation induces leukocyte production of tumor necrosis factor that critically contributes to mammary carcinogenesis

artículo científico publicado en 2010

Osteopontin shapes immunosuppression in the metastatic niche

artículo científico publicado en 2014

Overexpression of protectin (CD59) down-modulates the susceptibility of human melanoma cells to homologous complement

scientific article published on 01 December 2000

Peripheral regulatory T cells and serum transforming growth factor-β: relationship with clinical response to infliximab in Crohn's disease

artículo científico publicado en 2010

Persistent Immune Stimulation Exacerbates Genetically Driven Myeloproliferative Disorders via Stromal Remodeling.

artículo científico publicado en 2017

Polyps wrap mast cells and Treg within tumorigenic tentacles

artículo científico publicado en 2009

RORC1 Regulates Tumor-Promoting "Emergency" Granulo-Monocytopoiesis

artículo científico publicado en 2015

Reciprocal influence of B cells and tumor macro and microenvironments in the ApcMin/+ model of colorectal cancer.

artículo científico publicado en 2017

Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards

artículo científico publicado en 2016

Reconstitution of human telomerase reverse transcriptase expression rescues colorectal carcinoma cells from in vitro senescence: evidence against immortality as a constitutive trait of tumor cells

artículo científico publicado en 2005

Redundancy of autocrine loops in human rhabdomyosarcoma cells: induction of differentiation by suramin

artículo científico publicado en 1995

Refined localization of H7 and Ctt1 on distal mouse chromosome 9

scientific article published on 01 January 1994

Regulated Expression of miR-155 is Required for iNKT Cell Development

artículo científico publicado en 2015

Regulatory-T-cell inhibition versus depletion: the right choice in cancer immunotherapy

artículo científico publicado en 2007

Reversal of tumor-induced dendritic cell paralysis by CpG immunostimulatory oligonucleotide and anti-interleukin 10 receptor antibody

artículo científico publicado en 2002

Rheostatic Functions of Mast Cells in the Control of Innate and Adaptive Immune Responses

artículo científico publicado en 2017

Role of PLZF in melanoma progression.

artículo científico publicado en 2004

SCD5-induced oleic acid production reduces melanoma malignancy by intracellular retention of SPARC and cathepsin B.

artículo científico publicado en 2015

SOCS2 Controls Proliferation and Stemness of Hematopoietic Cells under Stress Conditions and Its Deregulation Marks Unfavorable Acute Leukemias

artículo científico publicado en 2015

SPARC oppositely regulates inflammation and fibrosis in bleomycin-induced lung damage

artículo científico publicado en 2011

Salmonella vaccine carrier strains: effective delivery system to trigger anti-tumor immunity by oral route

artículo científico publicado en 1999

Sarcoma Eradication by Doxorubicin and Targeted TNF Relies upon CD8+ T-cell Recognition of a Retroviral Antigen

artículo científico publicado en 2017

Separation of Dual Oxidase 2 and Lactoperoxidase Expression in Intestinal Crypts and Species Differences May Limit Hydrogen Peroxide Scavenging During Mucosal Healing in Mice and Humans

artículo científico publicado en 2017

Sequence of human GAS3/PMP22 full-length cDNA.

artículo científico publicado en 1993

Seventh annual meeting of the Italian Network for Tumor Biotherapy (NIBIT), Siena, 1-3 October 2009.

artículo científico publicado en 2010

Sixth annual meeting of the Italian network for tumor biotherapy (NIBIT), Siena, 16-18 October 2008.

artículo científico publicado en 2009

Smac mimetics induce inflammation and necrotic tumour cell death by modulating macrophage activity

artículo científico publicado en 2013

Stromal SPARC contributes to the detrimental fibrotic changes associated with myeloproliferation whereas its deficiency favors myeloid cell expansion.

artículo científico publicado en 2012

Stromal niche communalities underscore the contribution of the matricellular protein SPARC to B-cell development and lymphoid malignancies

artículo científico publicado en 2014

Targeting myelomonocytic cells to revert inflammation-dependent cancer promotion

artículo científico publicado en 2005

Tenth annual meeting of the Italian Network for Tumor Biotherapy (NIBIT), SIENA, Italy, November 5-7, 2012.

artículo científico publicado en 2013

The Italian Network for Tumor Biotherapy (NIBIT): getting together to push the field forward.

artículo científico publicado en 2008

The Role of Mast Cells in Molding the Tumor Microenvironment.

artículo científico

The aryl hydrocarbon receptor modulates acute and late mast cell responses

artículo científico publicado en 2012

The bone marrow stroma in hematological neoplasms--a guilty bystander.

artículo científico publicado en 2011

The dark side of mast cell-targeted therapy in prostate cancer

artículo científico publicado en 2012

The defined attenuated Listeria monocytogenes delta mp12 mutant is an effective oral vaccine carrier to trigger a long-lasting immune response against a mouse fibrosarcoma

artículo científico publicado en 1997

The good and bad of targeting cancer-associated extracellular matrix.

artículo científico publicado en 2017

The ins and outs of osteopontin

artículo científico publicado en 2015

The intriguing role of polymorphonuclear neutrophils in antitumor reactions.

artículo científico publicado en 2001

The matricellular protein SPARC supports follicular dendritic cell networking toward Th17 responses

article

The terminology issue for myeloid-derived suppressor cells

artículo científico publicado en 2007

Trabectedin Overrides Osteosarcoma Differentiative Block and Reprograms the Tumor Immune Environment Enabling Effective Combination with Immune Checkpoint Inhibitors

artículo científico publicado en 2017

Transcriptional Profiles and Stromal Changes Reveal Bone Marrow Adaptation to Early Breast Cancer in Association with Deregulated Circulating microRNAs

scientific article published on 27 November 2019

Treatment of a low immunogenic experimental tumour with alloactivated or tumour-immune lymphocytes

artículo científico publicado en 1987

Triggering CD40 on endothelial cells contributes to tumor growth

artículo científico publicado en 2006

Triggering of OX40 (CD134) on CD4(+)CD25+ T cells blocks their inhibitory activity: a novel regulatory role for OX40 and its comparison with GITR.

artículo científico publicado en 2004

Tumor and dendritic cells as cellular vaccines: confrontation and perspectives--a symposium in writing

scientific article published on 01 April 1998

Tumor-cell-targeted cytokine gene therapy

artículo científico publicado en 1991

Tumor-derived prostaglandin E2 promotes p50 NF-κB-dependent differentiation of monocytic MDSC

scientific article published on 07 April 2020

Tumor-induced expansion of regulatory T cells by conversion of CD4+CD25- lymphocytes is thymus and proliferation independent

artículo científico publicado en 2006

Ultrasound-guided intra-tumor injection of combined immunotherapy cures mice from orthotopic prostate cancer

artículo científico publicado en 2013

Vaccination of stage IV patients with allogeneic IL-4- or IL-2-gene-transduced melanoma cells generates functional antibodies against vaccinating and autologous melanoma cells

artículo científico publicado en 2001

When Failure Is Worse Than Giving Up: The Case of CTL

scientific article published on 01 April 2019

cIAP1 regulates the EGFR/Snai2 axis in triple-negative breast cancer cells.

artículo científico publicado en 2018

p50 Nuclear Factor- B Overexpression in Tumor-Associated Macrophages Inhibits M1 Inflammatory Responses and Antitumor Resistance

article

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda