Lista de obras - Lenka Skálová - Dominio Público Uruguay

A comparison between stereospecificity of oracin reduction and stereoselectivity of oxidation of 11-dihydrooracin enantiomersin vitro in rat and guinea pig

artículo científico publicado en 1999

Achiral and chiral high-performance liquid chromatographic determination of flubendazole and its metabolites in biomatrices using UV photodiode-array and mass spectrometric detection

artículo científico publicado en 2007

Activities of biotransformation enzymes in pheasant (Phasianus colchicus) and their modulation by in vivo administration of mebendazole and flubendazole

artículo científico publicado en 2007

Activity, stereospecificity, and stereoselectivity of microsomal enzymes in dependence on storage and freezing of rat liver samples

scientific article published on 01 October 2000

Age-related changes in hepatic activity and expression of detoxification enzymes in male rats

artículo científico publicado en 2013

Albendazole in environment: faecal concentrations in lambs and impact on lower development stages of helminths and seed germination.

artículo científico publicado en 2016

Albendazole repeated administration induces cytochromes P4501A and accelerates albendazole deactivation in mouflon (Ovis musimon).

artículo científico publicado en 2005

Altered cytochrome P450 activities and expression levels in the liver and intestines of the monosodium glutamate-induced mouse model of human obesity

artículo científico publicado en 2015

Antiproliferative Effects of Hop-derived Prenylflavonoids and Their Influence on the Efficacy of Oxaliplatine, 5-fluorouracil and Irinotecan in Human ColorectalC Cells

artículo científico publicado en 2019

Antiproliferative effect of benzimidazole anthelmintics albendazole, ricobendazole, and flubendazole in intestinal cancer cell lines.

artículo científico publicado en 2013

Biotransformation of albendazole and activities of selected detoxification enzymes in Haemonchus contortus strains susceptible and resistant to anthelmintics

artículo científico publicado en 2013

Biotransformation of anthelmintics and the activity of drug-metabolizing enzymes in the tapeworm Moniezia expansa

artículo científico publicado en 2014

Biotransformation of benzimidazole anthelmintics in reed (Phragmites australis) as a potential tool for their detoxification in environment

artículo científico publicado en 2013

Biotransformation of flobufen enantiomers in ruminant hepatocytes and subcellular fractions

artículo científico publicado en 2001

Biotransformation of flubendazole and fenbendazole and their effects in the ribwort plantain (Plantago lanceolata).

artículo científico publicado en 2017

Biotransformation of flubendazole and selected model xenobiotics in Haemonchus contortus

artículo científico publicado en 2007

Catechins Variously Affect Activities of Conjugation Enzymes in Proliferating and Differentiated Caco-2 Cells.

artículo científico publicado en 2016

Characterization of enzymes responsible for biotransformation of the new antileukotrienic drug quinlukast in rat liver microsomes and in primary cultures of rat hepatocytes

artículo científico publicado en 2004

Characterization of metabolites of sibutramine in primary cultures of rat hepatocytes by liquid chromatography-ion trap mass spectrometry

artículo científico publicado en 2008

Chiral aspects of metabolism of antiinflammatory drug flobufen in human hepatocytes

artículo científico publicado en 2003

Comparison of biotransformation and efficacy of aminoacetonitrile anthelminticsin vitro

Comparison of in vitro activities of biotransformation enzymes in pig, cattle, goat and sheep.

artículo científico publicado en 2004

Cranberry extract–enriched diets increase NAD(P)H:quinone oxidoreductase and catalase activities in obese but not in nonobese mice

artículo científico publicado en 2015

Design, Synthesis, and Biological Evaluation of Isothiosemicarbazones with Antimycobacterial Activity

artículo científico publicado en 2017

Drug-Metabolizing and Antioxidant Enzymes in Monosodium L-Glutamate Obese Mice

artículo científico publicado en 2014

Effect of ivermectin on activities of cytochrome P450 isoenzymes in mouflon (Ovis musimon) and fallow deer (Dama dama).

artículo científico publicado en 2001

Effect of oral administration of green tea extract in various dosage schemes on oxidative stress status of mice in vivo.

artículo científico publicado en 2015

Effect of selected catechins on doxorubicin antiproliferative efficacy and hepatotoxicity in vitro.

artículo científico publicado en 2014

Effect of standardized cranberry extract on the activity and expression of selected biotransformation enzymes in rat liver and intestine.

artículo científico publicado en 2014

Effect of substituents on microsomal reduction of benzo(c)fluorene N-oxides

artículo científico publicado en 2000

Efficacy of monepantel against lower developmental stages of a multi-resistant and susceptible Haemonchus contortus isolates: an in vitro study

scholarly article published by Lenka Lecová in 2013

Essential Oil from Myrica rubra Leaves Potentiated Antiproliferative and Prooxidative Effect of Doxorubicin and its Accumulation in Intestinal Cancer Cells

artículo científico publicado en 2015

Evaluation of drug uptake and deactivation in plant: Fate of albendazole in ribwort plantain (Plantago laceolata) cells and regenerants

artículo científico publicado en 2017

Factors affecting pharmacokinetics of benzimidazole anthelmintics in food-producing animals: the consequences and potential risks.

artículo científico publicado en 2011

Flubendazole induces mitotic catastrophe and senescence in colon cancer cells in vitro

artículo científico publicado en 2016

Flubendazole metabolism and biotransformation enzymes activities in healthy sheep and sheep with haemonchosis

artículo científico publicado en 2010

Hepatotoxicity of monoterpenes and sesquiterpenes.

artículo científico publicado en 2017

Import and efflux of flubendazole in Haemonchus contortus strains susceptible and resistant to anthelmintics ⬇️

artículo científico publicado el 21 de febrero de 2012

In vitro oxidative metabolism of xenobiotics in the lancet fluke (Dicrocoelium dendriticum) and the effects of albendazole and albendazole sulphoxide ex vivo

artículo científico publicado en 2010

Influence of diet supplementation with green tea extract on drug-metabolizing enzymes in a mouse model of monosodium glutamate-induced obesity

artículo científico publicado en 2015

Inhibition and induction of glutathione S-transferases by flavonoids: possible pharmacological and toxicological consequences ⬇️

artículo científico publicado el 24 de septiembre de 2012

Inhibitory effect of anthocyanidins on hepatic glutathione S-transferase, UDP-glucuronosyltransferase and carbonyl reductase activities in rat and human.

artículo científico publicado en 2013

Inter-Individual Variability in Acute Toxicity of R-Pulegone and R-Menthofuran in Human Liver Slices and Their Influence on miRNA Expression Changes in Comparison to Acetaminophen

artículo científico publicado en 2018

Inter-species comparisons of hepatic cytochrome P450 enzyme levels in male ruminants.

artículo científico publicado en 2003

Interaction of anthocyanins with drug-metabolizing and antioxidant enzymes.

artículo científico

Investigation of the metabolism of monepantel in ovine hepatocytes by UHPLC/MS/MS.

artículo científico publicado en 2012

Ivermectin-induced changes in the expression of cytochromes P450 and efflux transporters in Haemonchus contortus female and male adults

artículo científico publicado en 2019

LC-MS-MS identification of albendazole and flubendazole metabolites formed ex vivo by Haemonchus contortus.

artículo científico publicado en 2008

Liquid chromatography/mass spectrometric identification of benzimidazole anthelminthics metabolites formed ex vivo by Dicrocoelium dendriticum.

artículo científico publicado en 2009

Liver microsomal biotransformation of albendazole in deer, cattle, sheep and pig and some related wild breeds.

artículo científico publicado en 2005

Metabolic pathways of anthelmintic drug monepantel in sheep and in its parasite (Haemonchus contortus)

Metabolic pathways of benzimidazole anthelmintics in harebell (Campanula rotundifolia).

artículo científico publicado en 2016

Metabolism of drugs and other xenobiotics in giant liver fluke (Fascioloides magna).

artículo científico publicado en 2015

Modulation of porcine (Sus scrofa domestica) and pheasant (Phasianus colchicus) carbonyl reducing enzymes by anthelmintic therapy with flubendazole.

artículo científico publicado en 2008

Modulation of porcine biotransformation enzymes by anthelmintic therapy with fenbendazole and flubendazole

artículo científico publicado en 2005

Modulatory effects of quercetin and rutin on the activity, expression and inducibility of CYP1A1 in intestinal HCT-8 cells.

artículo científico publicado en 2013

Monepantel induces hepatic cytochromes p450 in sheep in vitro and in vivo

artículo científico publicado en 2014

Monepantel: the most studied new anthelmintic drug of recent years.

artículo científico

Mouflon (Ovis musimon) dicrocoeliosis: effects of parasitosis on the activities of biotransformation enzymes and albendazole metabolism in liver.

artículo científico publicado en 2007

Naturally occurring flavonoids as inhibitors of purified cytosolic glutathione S-transferase

artículo científico publicado en 2012

Nerolidol and Farnesol Inhibit Some Cytochrome P450 Activities but Did Not Affect Other Xenobiotic-Metabolizing Enzymes in Rat and Human Hepatic Subcellular Fractions.

artículo científico publicado en 2017

Paclitaxel conjugation with the analog of the gonadotropin-releasing hormone as a targeting moiety ⬇️

artículo científico publicado el 12 de junio de 2011

Pharmacokinetics of flubendazole and its metabolites in lambs and adult sheep (Ovis aries).

artículo científico publicado en 2009

Phase I biotransformation of albendazole in lancet fluke (Dicrocoelium dendriticum).

artículo científico publicado en 2008

Possibilities to increase the effectiveness of doxorubicin in cancer cells killing.

artículo científico publicado en 2011

Reduction of doxorubicin and oracin and induction of carbonyl reductase in human breast carcinoma MCF-7 cells.

artículo científico publicado en 2008

Reduction of flobufen in pig hepatocytes: effect of pig breed (domestic, wild) and castration.

artículo científico publicado en 2003

Reduction of the Potential Anticancer Drug Oracin in the Rat Liver In-vitro

artículo científico publicado en 2000

Reference genes for real-time PCR quantification of messenger RNAs and microRNAs in mouse model of obesity

artículo científico publicado en 2014

Reliable reference gene selection for quantitative real time PCR in Haemonchus contortus

artículo científico publicado en 2015

Sensitive chiral high-performance liquid chromatographic determination of anthelmintic flubendazole and its phase I metabolites in blood plasma using UV photodiode-array and fluorescence detection Application to pharmacokinetic studies in sheep

artículo científico publicado en 2008

Sertraline as a new potential anthelmintic against Haemonchus contortus: toxicity, efficacy, and biotransformation

artículo científico publicado en 2021

Sesquiterpenes Are Agonists of the Pregnane X Receptor but Do Not Induce the Expression of Phase I Drug-Metabolizing Enzymes in the Human Liver

scientific article published on 14 September 2019

Sex differences in stereospecificity of oracin reductases in ratin vitro andin vivo

artículo científico publicado en 1999

Stereochemical aspects of carbonyl reduction of the original anticancer drug oracin by mouse liver microsomes and purified 11beta-hydroxysteroid dehydrogenase type 1.

artículo científico publicado en 2003

Stereoselective pharmacokinetics of flobufen in rats

scientific article published on 01 January 1999

Stereospecific biotransformation of albendazole in mouflon and rat-isolated hepatocytes.

artículo científico publicado en 2003

Stereospecific reduction of the original anticancer drug oracin in rat extrahepatic tissues

scientific article published on 01 July 2003

Stereospecificity and stereoselectivity of flobufen metabolic profile in male rats in vitro and in vivo: phase I of biotransformation

artículo científico publicado en 2001

Stereospecificity of flobufen metabolism in guinea pigs in vitro and in vivo: phase I of biotransformation

artículo científico publicado en 2004

Sub-lethal doses of albendazole induce drug metabolizing enzymes and increase albendazole deactivation in Haemonchus contortus adults

scientific article published on 23 July 2020

The ATP bioluminescence assay: a new application and optimization for viability testing in the parasitic nematode Haemonchus contortus

artículo científico publicado en 2021

The Effects of Selected Sesquiterpenes from Myrica rubra Essential Oil on the Efficacy of Doxorubicin in Sensitive and Resistant Cancer Cell Lines.

artículo científico publicado en 2017

The Influence of Sesquiterpenes from Myrica rubra on the Antiproliferative and Pro-Oxidative Effects of Doxorubicin and Its Accumulation in Cancer Cells.

artículo científico publicado en 2015

The Modulation of Phase II Drug-Metabolizing Enzymes in Proliferating and Differentiated CaCo-2 Cells by Hop-Derived Prenylflavonoids

scientific article published on 18 July 2020

The Role of Xenobiotic-Metabolizing Enzymes in Anthelmintic Deactivation and Resistance in Helminths.

artículo científico publicado en 2016

The Selection and Validation of Reference Genes for mRNA and microRNA Expression Studies in Human Liver Slices Using RT-qPCR

artículo científico publicado en 2019

The activity of drug-metabolizing enzymes and the biotransformation of selected anthelmintics in the model tapeworm Hymenolepis diminuta

scientific article published on 06 February 2012

The effects of albendazole and its metabolites on hepatic cytochromes P450 activities in mouflon and rat.

artículo científico publicado en 2003

The effects of benzimidazole anthelmintics on P4501A in rat hepatocytes and HepG2 cells.

artículo científico publicado en 2003

The effects of fenbendazole, flubendazole and mebendazole on activities of hepatic cytochromes P450 in pig.

artículo científico publicado en 2004

The effects of flubendazole and mebendazole on cytochromes P4501A in pheasant hepatocytes.

artículo científico publicado en 2004

The effects of mebendazole on P4501A activity in rat hepatocytes and HepG2 cells. Comparison with tiabendazole and omeprazole

artículo científico publicado en 2003

The effects of β-caryophyllene oxide and trans-nerolidol on the efficacy of doxorubicin in breast cancer cells and breast tumor-bearing mice

artículo científico publicado en 2017

The inability of tapeworm Hymenolepis diminuta and fluke Dicrocoelium dendriticum to metabolize praziquantel

artículo científico publicado en 2011

The influence of oracin on reduction and toxicity of doxorubicin in hepatocytes and mammary epithelial cells MCF-10A.

artículo científico publicado en 2012

The inhibitory effects of β-caryophyllene, β-caryophyllene oxide and α-humulene on the activities of the main drug-metabolizing enzymes in rat and human liver in vitro.

artículo científico publicado en 2017

The metabolic fate of ivermectin in host (Ovis aries) and parasite (Haemonchus contortus).

artículo científico publicado en 2012

The metabolism of flubendazole and the activities of selected biotransformation enzymes in Haemonchus contortus strains susceptible and resistant to anthelmintics

artículo científico publicado en 2012

The metabolism of flubendazole in human liver and cancer cell lines.

artículo científico publicado en 2018

The modulation of carbonyl reductase 1 by polyphenols

artículo científico

The novel anticancer drug oracin: different stereospecificity and cooperativity for carbonyl reduction by purified human liver 11beta-hydroxysteroid dehydrogenase type 1.

artículo científico publicado en 2004

The role of aryl hydrocarbon receptor in regulation of enzymes involved in metabolic activation of polycyclic aromatic hydrocarbons in a model of rat liver progenitor cells.

artículo científico publicado en 2009

The stereoselective biotransformation of the anti-obesity drug sibutramine in rat liver microsomes and in primary cultures of rat hepatocytes

artículo científico publicado en 2005

The transport of albendazole and albendazole sulphoxide in the lancet fluke (Dicrocoelium dendriticum)

artículo científico publicado en 2010

UDP-glycosyltransferase family in Haemonchus contortus: Phylogenetic analysis, constitutive expression, sex-differences and resistance-related differences

artículo científico publicado en 2018

Use of chiral liquid chromatography for the evaluation of stereospecificity in the carbonyl reduction of potential benzo[c]fluorene antineoplastics benfluron and dimefluron in various species.

artículo científico publicado en 2004

Veterinary drugs in the environment and their toxicity to plants.

artículo científico publicado en 2015

Xenobiotic metabolizing enzymes and metabolism of anthelminthics in helminths.

artículo científico publicado en 2009

Xenobiotic-metabolizing enzymes in plants and their role in uptake and biotransformation of veterinary drugs in the environment

artículo científico publicado en 2015

Lista de obras de Lenka Skálová

A comparison between stereospecificity of oracin reduction and stereoselectivity of oxidation of 11-dihydrooracin enantiomersin vitro in rat and guinea pig

Achiral and chiral high-performance liquid chromatographic determination of flubendazole and its metabolites in biomatrices using UV photodiode-array and mass spectrometric detection

Activities of biotransformation enzymes in pheasant (Phasianus colchicus) and their modulation by in vivo administration of mebendazole and flubendazole

Activity, stereospecificity, and stereoselectivity of microsomal enzymes in dependence on storage and freezing of rat liver samples

Age-related changes in hepatic activity and expression of detoxification enzymes in male rats

Albendazole in environment: faecal concentrations in lambs and impact on lower development stages of helminths and seed germination.

Albendazole repeated administration induces cytochromes P4501A and accelerates albendazole deactivation in mouflon (Ovis musimon).

Altered cytochrome P450 activities and expression levels in the liver and intestines of the monosodium glutamate-induced mouse model of human obesity

Antiproliferative Effects of Hop-derived Prenylflavonoids and Their Influence on the Efficacy of Oxaliplatine, 5-fluorouracil and Irinotecan in Human ColorectalC Cells

Antiproliferative effect of benzimidazole anthelmintics albendazole, ricobendazole, and flubendazole in intestinal cancer cell lines.

Biotransformation of albendazole and activities of selected detoxification enzymes in Haemonchus contortus strains susceptible and resistant to anthelmintics

Biotransformation of anthelmintics and the activity of drug-metabolizing enzymes in the tapeworm Moniezia expansa

Biotransformation of benzimidazole anthelmintics in reed (Phragmites australis) as a potential tool for their detoxification in environment

Biotransformation of flobufen enantiomers in ruminant hepatocytes and subcellular fractions

Biotransformation of flubendazole and fenbendazole and their effects in the ribwort plantain (Plantago lanceolata).

Biotransformation of flubendazole and selected model xenobiotics in Haemonchus contortus

Catechins Variously Affect Activities of Conjugation Enzymes in Proliferating and Differentiated Caco-2 Cells.

Characterization of enzymes responsible for biotransformation of the new antileukotrienic drug quinlukast in rat liver microsomes and in primary cultures of rat hepatocytes

Characterization of metabolites of sibutramine in primary cultures of rat hepatocytes by liquid chromatography-ion trap mass spectrometry

Chiral aspects of metabolism of antiinflammatory drug flobufen in human hepatocytes

Comparison of biotransformation and efficacy of aminoacetonitrile anthelminticsin vitro

Comparison of in vitro activities of biotransformation enzymes in pig, cattle, goat and sheep.

Cranberry extract–enriched diets increase NAD(P)H:quinone oxidoreductase and catalase activities in obese but not in nonobese mice

Design, Synthesis, and Biological Evaluation of Isothiosemicarbazones with Antimycobacterial Activity

Drug-Metabolizing and Antioxidant Enzymes in Monosodium L-Glutamate Obese Mice

Effect of ivermectin on activities of cytochrome P450 isoenzymes in mouflon (Ovis musimon) and fallow deer (Dama dama).

Effect of oral administration of green tea extract in various dosage schemes on oxidative stress status of mice in vivo.

Effect of selected catechins on doxorubicin antiproliferative efficacy and hepatotoxicity in vitro.

Effect of standardized cranberry extract on the activity and expression of selected biotransformation enzymes in rat liver and intestine.

Effect of substituents on microsomal reduction of benzo(c)fluorene N-oxides

Efficacy of monepantel against lower developmental stages of a multi-resistant and susceptible Haemonchus contortus isolates: an in vitro study

Essential Oil from Myrica rubra Leaves Potentiated Antiproliferative and Prooxidative Effect of Doxorubicin and its Accumulation in Intestinal Cancer Cells

Evaluation of drug uptake and deactivation in plant: Fate of albendazole in ribwort plantain (Plantago laceolata) cells and regenerants

Factors affecting pharmacokinetics of benzimidazole anthelmintics in food-producing animals: the consequences and potential risks.

Flubendazole induces mitotic catastrophe and senescence in colon cancer cells in vitro

Flubendazole metabolism and biotransformation enzymes activities in healthy sheep and sheep with haemonchosis

Hepatotoxicity of monoterpenes and sesquiterpenes.

Import and efflux of flubendazole in Haemonchus contortus strains susceptible and resistant to anthelmintics ⬇️

In vitro oxidative metabolism of xenobiotics in the lancet fluke (Dicrocoelium dendriticum) and the effects of albendazole and albendazole sulphoxide ex vivo

Influence of diet supplementation with green tea extract on drug-metabolizing enzymes in a mouse model of monosodium glutamate-induced obesity

Inhibition and induction of glutathione S-transferases by flavonoids: possible pharmacological and toxicological consequences ⬇️

Inhibitory effect of anthocyanidins on hepatic glutathione S-transferase, UDP-glucuronosyltransferase and carbonyl reductase activities in rat and human.

Inter-Individual Variability in Acute Toxicity of R-Pulegone and R-Menthofuran in Human Liver Slices and Their Influence on miRNA Expression Changes in Comparison to Acetaminophen

Inter-species comparisons of hepatic cytochrome P450 enzyme levels in male ruminants.

Interaction of anthocyanins with drug-metabolizing and antioxidant enzymes.

Investigation of the metabolism of monepantel in ovine hepatocytes by UHPLC/MS/MS.

Ivermectin-induced changes in the expression of cytochromes P450 and efflux transporters in Haemonchus contortus female and male adults

LC-MS-MS identification of albendazole and flubendazole metabolites formed ex vivo by Haemonchus contortus.

Liquid chromatography/mass spectrometric identification of benzimidazole anthelminthics metabolites formed ex vivo by Dicrocoelium dendriticum.

Liver microsomal biotransformation of albendazole in deer, cattle, sheep and pig and some related wild breeds.

Metabolic pathways of anthelmintic drug monepantel in sheep and in its parasite (Haemonchus contortus)

Metabolic pathways of benzimidazole anthelmintics in harebell (Campanula rotundifolia).

Metabolism of drugs and other xenobiotics in giant liver fluke (Fascioloides magna).

Modulation of porcine (Sus scrofa domestica) and pheasant (Phasianus colchicus) carbonyl reducing enzymes by anthelmintic therapy with flubendazole.

Modulation of porcine biotransformation enzymes by anthelmintic therapy with fenbendazole and flubendazole

Modulatory effects of quercetin and rutin on the activity, expression and inducibility of CYP1A1 in intestinal HCT-8 cells.

Monepantel induces hepatic cytochromes p450 in sheep in vitro and in vivo

Monepantel: the most studied new anthelmintic drug of recent years.

Mouflon (Ovis musimon) dicrocoeliosis: effects of parasitosis on the activities of biotransformation enzymes and albendazole metabolism in liver.

Naturally occurring flavonoids as inhibitors of purified cytosolic glutathione S-transferase

Nerolidol and Farnesol Inhibit Some Cytochrome P450 Activities but Did Not Affect Other Xenobiotic-Metabolizing Enzymes in Rat and Human Hepatic Subcellular Fractions.

Paclitaxel conjugation with the analog of the gonadotropin-releasing hormone as a targeting moiety ⬇️

Pharmacokinetics of flubendazole and its metabolites in lambs and adult sheep (Ovis aries).

Phase I biotransformation of albendazole in lancet fluke (Dicrocoelium dendriticum).

Possibilities to increase the effectiveness of doxorubicin in cancer cells killing.

Reduction of doxorubicin and oracin and induction of carbonyl reductase in human breast carcinoma MCF-7 cells.

Reduction of flobufen in pig hepatocytes: effect of pig breed (domestic, wild) and castration.

Reduction of the Potential Anticancer Drug Oracin in the Rat Liver In-vitro

Reference genes for real-time PCR quantification of messenger RNAs and microRNAs in mouse model of obesity

Reliable reference gene selection for quantitative real time PCR in Haemonchus contortus

Sensitive chiral high-performance liquid chromatographic determination of anthelmintic flubendazole and its phase I metabolites in blood plasma using UV photodiode-array and fluorescence detection Application to pharmacokinetic studies in sheep

Sertraline as a new potential anthelmintic against Haemonchus contortus: toxicity, efficacy, and biotransformation

Sesquiterpenes Are Agonists of the Pregnane X Receptor but Do Not Induce the Expression of Phase I Drug-Metabolizing Enzymes in the Human Liver

Sex differences in stereospecificity of oracin reductases in ratin vitro andin vivo

Stereochemical aspects of carbonyl reduction of the original anticancer drug oracin by mouse liver microsomes and purified 11beta-hydroxysteroid dehydrogenase type 1.

Stereoselective pharmacokinetics of flobufen in rats

Stereospecific biotransformation of albendazole in mouflon and rat-isolated hepatocytes.

Stereospecific reduction of the original anticancer drug oracin in rat extrahepatic tissues

Stereospecificity and stereoselectivity of flobufen metabolic profile in male rats in vitro and in vivo: phase I of biotransformation