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Lista de obras de Rodrigo B. Leal

A single high dose of dexamethasone affects the phosphorylation state of glutamate AMPA receptors in the human limbic system

artículo científico publicado en 2016

Acute agmatine administration, similar to ketamine, reverses depressive-like behavior induced by chronic unpredictable stress in mice

artículo científico publicado en 2016

Agmatine enhances antidepressant potency of MK-801 and conventional antidepressants in mice

artículo científico publicado en 2014

Agmatine potentiates neuroprotective effects of subthreshold concentrations of ketamine via mTOR/S6 kinase signaling pathway.

artículo científico publicado en 2018

Agmatine produces antidepressant-like effects by activating AMPA receptors and mTOR signaling

artículo científico publicado en 2016

Amygdala levels of the GluA1 subunit of glutamate receptors and its phosphorylation state at serine 845 in the anterior hippocampus are biomarkers of ictal fear but not anxiety.

artículo científico publicado en 2018

Anti-glioma properties of DVL, a lectin purified from Dioclea violacea

scientific article published on 23 August 2018

Antidepressant-like action of the bark ethanolic extract from Tabebuia avellanedae in the olfactory bulbectomized mice.

artículo científico publicado en 2012

Antidepressant-like effect of Canavalia brasiliensis (ConBr) lectin in mice: evidence for the involvement of the glutamatergic system

artículo científico publicado en 2014

Antidepressant-like effect of lectin from Canavalia brasiliensis (ConBr) administered centrally in mice.

artículo científico publicado en 2006

Antidepressant-like effect of the organoselenium compound ebselen in mice: evidence for the involvement of the monoaminergic system.

artículo científico publicado en 2008

Antidepressant-like effect of zinc is dependent on signaling pathways implicated in BDNF modulation

artículo científico publicado en 2015

Antioxidant effect of diphenyl diselenide against sodium nitroprusside (SNP) induced lipid peroxidation in human platelets and erythrocyte membranes: an in vitro evaluation

artículo científico publicado en 2006

Atorvastatin Prevents Glutamate Uptake Reduction Induced by Quinolinic Acid Via MAPKs Signaling.

artículo científico publicado en 2016

Biochemical alterations in caged Nile tilapia Oreochromis niloticus

artículo científico publicado en 2010

Biochemical alterations in juvenile carp (Cyprinus carpio) exposed to zinc: glutathione reductase as a target

artículo científico publicado en 2008

Cadmium stimulates MAPKs and Hsp27 phosphorylation in bovine adrenal chromaffin cells

artículo científico publicado en 2007

Calcium-dependent phosphorylation of glial fibrillary acidic protein (GFAP) in the rat hippocampus: a comparison of the kinase/phosphatase balance in immature and mature slices using tryptic phosphopeptide mapping

artículo científico publicado en 1997

Canavalia bonariensis lectin: Molecular bases of glycoconjugates interaction and antiglioma potential.

artículo científico

Comparative study on methyl- and ethylmercury-induced toxicity in C6 glioma cells and the potential role of LAT-1 in mediating mercurial-thiol complexes uptake

artículo científico publicado en 2013

ConBr, A Lectin Purified from the Seeds of Canavalia brasiliensis, Protects Against Ischemia in Organotypic Culture of Rat Hippocampus: Potential Implication of Voltage-Gated Calcium Channels.

artículo científico publicado en 2016

ConBr, a lectin from Canavalia brasiliensis seeds, modulates signaling pathways and increases BDNF expression probably via a glycosylated target

artículo científico publicado en 2014

ConBr, a lectin from Canavalia brasiliensis seeds, protects against quinolinic acid-induced seizures in mice.

artículo científico publicado en 2011

Congenital hypothyroidism alters the phosphorylation of ERK1/2 and p38MAPK in the hippocampus of neonatal rats

artículo científico publicado en 2005

Creb is modulated in the mouse superior colliculus in developmental and experimentally-induced models of plasticity

artículo científico publicado en 2012

Crystal structure of DlyL, a mannose-specific lectin from Dioclea lasiophylla Mart. Ex Benth seeds that display cytotoxic effects against C6 glioma cells.

artículo científico publicado en 2018

Crystal structure of Pisum arvense seed lectin (PAL) and characterization of its interaction with carbohydrates by molecular docking and dynamics

artículo científico publicado en 2017

Developmental changes in content of glial marker proteins in rats exposed to protein malnutrition

artículo científico publicado en 2007

Developmental exposure to manganese induces lasting motor and cognitive impairment in rats

artículo científico publicado en 2015

Differential Activation of Mitogen-Activated Protein Kinases, ERK 1/2, p38(MAPK) and JNK p54/p46 During Postnatal Development of Rat Hippocampus

artículo científico publicado en 2015

Diphenyl diselenide confers neuroprotection against hydrogen peroxide toxicity in hippocampal slices

artículo científico publicado en 2008

Diphenyl diselenide induces apoptotic cell death and modulates ERK1/2 phosphorylation in human neuroblastoma SH-SY5Y cells

artículo científico publicado en 2010

EGF-FGF2 stimulates the proliferation and improves the neuronal commitment of mouse epidermal neural crest stem cells (EPI-NCSCs).

artículo científico publicado en 2014

Effect of the lectin of Bauhinia variegata and its recombinant isoform on surgically induced skin wounds in a murine model

artículo científico publicado en 2011

Effects of pentylenetetrazole kindling on mitogen-activated protein kinases levels in neocortex and hippocampus of mice

artículo científico publicado en 2014

Enhancement of memory consolidation by the histone deacetylase inhibitor sodium butyrate in aged rats

artículo científico publicado en 2015

Epigallocatechin-3-gallate protects rat brain mitochondria against cadmium-induced damage

artículo científico publicado en 2011

Exercise attenuates levodopa-induced dyskinesia in 6-hydroxydopamine-lesioned mice

artículo científico publicado en 2013

Exposure of C6 glioma cells to Pb(II) increases the phosphorylation of p38(MAPK) and JNK1/2 but not of ERK1/2.

artículo científico publicado en 2007

Fluoxetine modulates hippocampal cell signaling pathways implicated in neuroplasticity in olfactory bulbectomized mice.

artículo científico publicado en 2012

Glutamate-induced toxicity in hippocampal slices involves apoptotic features and p38 MAPK signaling

artículo científico publicado en 2007

Glutamatergic system and mTOR-signaling pathway participate in the antidepressant-like effect of inosine in the tail suspension test.

artículo científico publicado en 2017

High-intensity physical exercise disrupts implicit memory in mice: involvement of the striatal glutathione antioxidant system and intracellular signaling

artículo científico publicado en 2010

In vitro manganese exposure disrupts MAPK signaling pathways in striatal and hippocampal slices from immature rats

artículo científico publicado en 2013

In vivo manganese exposure modulates Erk, Akt and Darpp-32 in the striatum of developing rats, and impairs their motor function

artículo científico publicado en 2012

Involvement of PI3K, GSK-3β and PPARγ in the antidepressant-like effect of folic acid in the forced swimming test in mice

artículo científico publicado en 2011

Involvement of PI3K/Akt Signaling Pathway and Its Downstream Intracellular Targets in the Antidepressant-Like Effect of Creatine.

artículo científico publicado en 2015

Involvement of PKA, PKC, CAMK-II and MEK1/2 in the acute antidepressant-like effect of creatine in mice.

artículo científico publicado en 2014

Involvement of glutathione, ERK1/2 phosphorylation and BDNF expression in the antidepressant-like effect of zinc in rats.

artículo científico publicado en 2007

Involvement of p38MAPK on the antinociceptive action of myricitrin in mice

scientific article published on 22 June 2007

Involvement of the S100B in cAMP-induced cytoskeleton remodeling in astrocytes: a study using TRTK-12 in digitonin-permeabilized cells

artículo científico publicado en 2004

Knockdown of Carboxypeptidase A6 in Zebrafish Larvae Reduces Response to Seizure-Inducing Drugs and Causes Changes in the Level of mRNAs Encoding Signaling Molecules

artículo científico publicado en 2016

Lead stimulates ERK1/2 and p38MAPK phosphorylation in the hippocampus of immature rats

artículo científico publicado en 2004

Lead-Stimulated p38MAPK-Dependent Hsp27 Phosphorylation

artículo científico publicado en 2002

Lectin from Canavalia brasiliensis (ConBr) protects hippocampal slices against glutamate neurotoxicity in a manner dependent of PI3K/Akt pathway

artículo científico publicado en 2013

Lectin from Dioclea violacea induces autophagy in U87 glioma cells

scientific article published on 01 May 2019

Manganese induces sustained Ser40 phosphorylation and activation of tyrosine hydroxylase in PC12 cells.

artículo científico publicado en 2009

Manganese-exposed developing rats display motor deficits and striatal oxidative stress that are reversed by Trolox

artículo científico publicado en 2013

Mechanism of guanosine-induced neuroprotection in rat hippocampal slices submitted to oxygen-glucose deprivation

scientific article published on 01 August 2007

Mercurial-induced hydrogen peroxide generation in mouse brain mitochondria: protective effects of quercetin.

artículo científico publicado en 2007

Methylglyoxal-Mediated Dopamine Depletion, Working Memory Deficit, and Depression-Like Behavior Are Prevented by a Dopamine/Noradrenaline Reuptake Inhibitor

scientific article published on 04 October 2020

Mitochondrial Respiration Chain Enzymatic Activities in the Human Brain: Methodological Implications for Tissue Sampling and Storage.

artículo científico publicado en 2015

Modulation of Brain Glutathione Reductase and Peroxiredoxin 2 by α-Tocopheryl Phosphate.

artículo científico publicado en 2016

Modulation of ERK1/2 and p38(MAPK) by lead in the cerebellum of Brazilian catfish Rhamdia quelen

scientific article published on 19 December 2005

Molecular modeling, docking and dynamics simulations of the Dioclea lasiophylla Mart. Ex Benth seed lectin: An edematogenic and hypernociceptive protein.

artículo científico publicado en 2017

Neuroglial alterations in rats submitted to the okadaic acid-induced model of dementia.

artículo científico publicado en 2011

Neuropsychological functioning and brain energetics of drug resistant mesial temporal lobe epilepsy patients.

artículo científico publicado en 2017

Neurotoxicity of cadmium on immature hippocampus and a neuroprotective role for p38 MAPK.

artículo científico publicado en 2008

One century of ConA and 40 years of ConBr research: A structural review

artículo científico publicado en 2019

Partial characterization and immobilization in CNBr-activated Sepharose of a native lectin from Platypodium elegans seeds (PELa) and comparative study of edematogenic effect with the recombinant form

artículo científico publicado en 2017

Protective Effects of Ursolic Acid Against Cytotoxicity Induced by Corticosterone: Role of Protein Kinases

scientific article published on 11 November 2019

Protective effects of resveratrol on hydrogen peroxide induced toxicity in primary cortical astrocyte cultures

artículo científico publicado en 2007

Purification and characterization of a mannose/N-acetyl-D-glucosamine-specific lectin from the seeds of Platymiscium floribundum Vogel

artículo científico publicado en 2012

Purification and partial characterization of a new mannose/glucose-specific lectin from Dialium guineense Willd seeds that exhibits toxic effect.

artículo científico publicado en 2013

Region-specific alterations of AMPA receptor phosphorylation and signaling pathways in the pilocarpine model of epilepsy.

artículo científico publicado en 2015

Regional distribution and properties of an enzyme system in rat brain that phosphorylates ppH-47, an insoluble protein highly labelled in tissue slices from the hippocampus

artículo científico publicado en 1991

Regional variations in protein phosphorylating activity in rat brain studied in micro-slices labeled with [32P]phosphate

artículo científico publicado en 1990

Resveratrol protects against oxidative injury induced by H2O2 in acute hippocampal slice preparations from Wistar rats.

artículo científico publicado en 2008

Riboflavin acetate induces apoptosis in squamous carcinoma cells after photodynamic therapy.

artículo científico publicado en 2015

Role of Caenorhabditis elegans AKT-1/2 and SGK-1 in Manganese Toxicity

artículo científico publicado en 2018

Role of Phosphatidylinositol-3 Kinase Pathway in NMDA Preconditioning: Different Mechanisms for Seizures and Hippocampal Neuronal Degeneration Induced by Quinolinic Acid.

artículo científico publicado en 2018

S100B protein stimulates calcineurin activity

artículo científico publicado en 2004

S100B secretion is stimulated by IL-1beta in glial cultures and hippocampal slices of rats: Likely involvement of MAPK pathway

artículo científico publicado en 2008

S100B-mediated inhibition of the phosphorylation of GFAP is prevented by TRTK-12.

artículo científico publicado en 2004

Signaling pathways underlying the antidepressant-like effect of inosine in mice

artículo científico publicado en 2016

Single administration of agmatine reverses the depressive-like behavior induced by corticosterone in mice: Comparison with ketamine and fluoxetine

scientific article published on 18 August 2018

Sodium selenite protects from 3-nitropropionic acid-induced oxidative stress in cultured primary cortical neurons

artículo científico publicado en 2018

Structural analysis of Centrolobium tomentosum seed lectin with inflammatory activity

artículo científico publicado en 2016

Structural analysis of Dioclea lasiocarpa lectin: A C6 cells apoptosis-inducing protein.

artículo científico publicado en 2017

Structural characterization of a lectin from Canavalia virosa seeds with inflammatory and cytotoxic activities

artículo científico publicado en 2016

Structural studies of a vasorelaxant lectin from Dioclea reflexa Hook seeds: Crystal structure, molecular docking and dynamics.

artículo científico publicado en 2017

Sub-chronic agmatine treatment modulates hippocampal neuroplasticity and cell survival signaling pathways in mice.

artículo científico publicado en 2014

Subchronic administration of ascorbic acid elicits antidepressant-like effect and modulates cell survival signaling pathways in mice

artículo científico publicado en 2016

TNF-α-induced depressive-like phenotype and p38(MAPK) activation are abolished by ascorbic acid treatment

artículo científico publicado en 2015

The S100B protein inhibits phosphorylation of GFAP and vimentin in a cytoskeletal fraction from immature rat hippocampus

artículo científico publicado en 1998

The activation of ERK1/2 and p38 mitogen-activated protein kinases is dynamically regulated in the developing rat visual system

artículo científico publicado en 2008

The flavonoids hesperidin and rutin promote neural crest cell survival.

artículo científico publicado en 2012

Time course evaluation of behavioral impairments in the pilocarpine model of epilepsy

artículo científico publicado en 2016

Time-dependent modulation of AMPA receptor phosphorylation and mRNA expression of NMDA receptors and glial glutamate transporters in the rat hippocampus and cerebral cortex in a pilocarpine model of epilepsy

artículo científico publicado en 2013

Time-dependent modulation of mitogen activated protein kinases and AKT in rat hippocampus and cortex in the pilocarpine model of epilepsy

artículo científico publicado en 2012

Tyrosine hydroxylase dephosphorylation by protein phosphatase 2A in bovine adrenal chromaffin cells

artículo científico publicado en 2002

Tyrosine hydroxylase phosphorylation in bovine adrenal chromaffin cells: the role of MAPKs after angiotensin II stimulation

artículo científico publicado en 2001

Tyrosine hydroxylase regulation in adult rat striatum following short-term neonatal exposure to manganese

artículo científico publicado en 2016

Variant vicilins from a resistant Vigna unguiculata lineage (IT81D-1053) accumulate inside Callosobruchus maculatus larval midgut epithelium

artículo científico publicado en 2013

Vatairea macrocarpa lectin (VML) induces depressive-like behavior and expression of neuroinflammatory markers in mice.

artículo científico publicado en 2013

Zinc reverses malathion-induced impairment in antioxidant defenses.

artículo científico publicado en 2009