Lista de obras - Erik Wiemer - Dominio Público Uruguay

A pharmacogenetic predictive model for paclitaxel clearance based on the DMET platform

artículo científico publicado en 2013

A small mammal model of tumour implantation, dissemination and growth factor expression after partial hepatectomy.

artículo científico publicado en 2007

Aberrant MicroRNA Expression and Its Implications for Uveal Melanoma Metastasis

artículo científico publicado en 2019

Absence of mutations in the deoxycytidine kinase (dCK) gene in patients with relapsed and/or refractory acute myeloid leukemia (AML).

artículo científico publicado en 2001

Activated Signaling Pathways and Targeted Therapies in Desmoid-Type Fibromatosis: A Literature Review.

artículo científico publicado en 2019

CYP3A4*22 genotype and systemic exposure affect paclitaxel-induced neurotoxicity.

artículo científico publicado en 2013

Can "specific" OCT1 inhibitors be used to determine OCT1 transporter activity toward imatinib?

artículo científico publicado en 2013

Cell-type-specific role of CHK2 in mediating DNA damage-induced G2 cell cycle arrest

artículo científico publicado en 2020

Circadian variation in tamoxifen pharmacokinetics in mice and breast cancer patients.

artículo científico publicado en 2015

Cross-resistance between taxanes and new hormonal agents abiraterone and enzalutamide may affect drug sequence choices in metastatic castration-resistant prostate cancer.

artículo científico publicado en 2013

DNA damage responsive microRNAs misexpressed in human cancer modulate therapy sensitivity

artículo científico publicado en 2013

Deregulated microRNAs in neurofibromatosis type 1 derived malignant peripheral nerve sheath tumors

artículo científico publicado en 2020

Dose selection in phase I studies: why we should always go for the top

artículo científico publicado en 2008

Early cessation of the clinical development of LiPlaCis, a liposomal cisplatin formulation.

artículo científico publicado en 2010

Editorial: the long and winding road to better cancer cell-specific therapies

scientific article published on 01 May 2008

Effect of omeprazole on the pharmacokinetics and toxicities of irinotecan in cancer patients: a prospective cross-over drug-drug interaction study.

artículo científico publicado en 2011

Effects of methimazole on the elimination of irinotecan.

artículo científico publicado en 2010

Evaluation of patient enrollment in oncology phase I clinical trials.

artículo científico publicado en 2013

Expression and inhibition of BRD4, EZH2 and TOP2A in neurofibromas and malignant peripheral nerve sheath tumors.

artículo científico publicado en 2017

Fasting protects against the side effects of irinotecan treatment but does not affect anti-tumour activity in mice

artículo científico publicado en 2015

Host resistance to lung infection mediated by major vault protein in epithelial cells

artículo científico publicado en 2007

Identification of multidrug resistance-associated protein 1 and glutathione as multidrug resistance mechanisms in human prostate cancer cells: chemosensitization with leukotriene D4 antagonists and buthionine sulfoximine.

artículo científico publicado en 2004

Improved insight into resistance mechanisms to imatinib in gastrointestinal stromal tumors: a basis for novel approaches and individualization of treatment

artículo científico publicado en 2007

Incident cancer risk after the start of aspirin use: results from a Dutch population-based cohort study of low dose aspirin users

artículo científico publicado en 2013

Increased expression of the breast cancer resistance protein (BCRP) in relapsed or refractory acute myeloid leukemia (AML)

artículo científico publicado en 2002

Inducible Major Vault Protein Plays a Pivotal Role in Double-Stranded RNA- or Virus-Induced Proinflammatory Response.

artículo científico publicado en 2016

Influence of smoking on the pharmacokinetics and toxicity profiles of taxane therapy

artículo científico publicado en 2012

Inhibition of activin-like kinase 4/5 attenuates cancer cachexia associated muscle wasting

scientific article published on 08 July 2019

Isolation and characterization of Pas2p, a peroxisomal membrane protein essential for peroxisome biogenesis in the methylotrophic yeast Pichia pastoris.

artículo científico publicado en 1996

Kinetics of the assembly of peroxisomes after fusion of complementary cell lines from patients with the cerebro-hepato-renal (Zellweger) syndrome and related disorders

scientific article published on 01 May 1988

Loss of E-cadherin is not a necessity for epithelial to mesenchymal transition in human breast cancer.

artículo científico publicado en 2013

Loss of SLCO1B3 drives taxane resistance in prostate cancer

artículo científico publicado en 2016

MDR1 expression in poor-risk acute myeloid leukemia with partial or complete monosomy 7.

artículo científico publicado en 2001

MDR1 gene-related clonal selection and P-glycoprotein function and expression in relapsed or refractory acute myeloid leukemia

artículo científico publicado en 2001

Macrocytosis as a potential parameter associated with survival after tyrosine kinase inhibitor treatment.

artículo científico publicado en 2016

Major vault protein suppresses obesity and atherosclerosis through inhibiting IKK-NF-κB signaling mediated inflammation

artículo científico publicado en 2019

Major vault protein, a candidate gene in 16p11.2 microdeletion syndrome, is required for the homeostatic regulation of visual cortical plasticity.

artículo científico publicado en 2018

Major vault protein, in concert with constitutively photomorphogenic 1, negatively regulates c-Jun-mediated activator protein 1 transcription in mammalian cells

artículo científico publicado en 2005

MiR-17-92 and miR-221/222 cluster members target KIT and ETV1 in human gastrointestinal stromal tumours

artículo científico publicado en 2013

MiR-193b promotes autophagy and non-apoptotic cell death in oesophageal cancer cells

artículo científico publicado en 2016

MicroRNA expression and DNA methylation profiles do not distinguish between primary and recurrent well-differentiated liposarcoma

scientific article published on 23 January 2020

MicroRNA expression profiles distinguish liposarcoma subtypes and implicate miR-145 and miR-451 as tumor suppressors.

artículo científico publicado en 2014

MicroRNA markers for forensic body fluid identification obtained from microarray screening and quantitative RT-PCR confirmation

artículo científico publicado en 2010

MicroRNA regulation of RAD51 in serous ovarian cancer modulates chemotherapy response

artículo científico publicado en 2015

MicroRNA response to hypoxic stress in soft tissue sarcoma cells: microRNA mediated regulation of HIF3α

artículo científico publicado en 2014

MicroRNA-mediated gene silencing modulates the UV-induced DNA-damage response

artículo científico publicado en 2009

MicroRNAs as possible indicators of drug sensitivity in breast cancer cell lines

artículo científico publicado en 2019

MicroRNAs in ovarian cancer biology and therapy resistance.

artículo científico publicado en 2010

Multiple human vault RNAs. Expression and association with the vault complex

artículo científico publicado en 2001

Non-Coding RNAs, a Novel Paradigm for the Management of Gastrointestinal Stromal Tumors

scientific article published on 22 September 2020

Phase I pharmacokinetic and pharmacodynamic study of the first-in-class spliceosome inhibitor E7107 in patients with advanced solid tumors.

artículo científico publicado en 2013

Phase I study of RGB-286638, a novel, multitargeted cyclin-dependent kinase inhibitor in patients with solid tumors

artículo científico publicado en 2014

Phase I study of cisplatin, hyperthermia, and lapatinib in patients with recurrent carcinoma of the uterine cervix in a previously irradiated area

artículo científico publicado en 2015

Phenotypic heterogeneity in cultured skin fibroblasts from patients with disorders of peroxisome biogenesis belonging to the same complementation group

artículo científico publicado en 1991

Pitfalls of the application of microdialysis in clinical oncology: controversial findings with docetaxel.

artículo científico publicado en 2007

Practical aspects of managing gastrointestinal stromal tumors.

artículo científico publicado en 2006

Prenatal diagnosis of Zellweger syndrome by direct visualization of peroxisomes in chorionic villus fibroblasts by immunofluorescence microscopy

artículo científico publicado en 1989

Production and characterisation of monoclonal antibodies against native and disassembled human catalase

scientific article published on 01 July 1992

Prognostic Circulating MicroRNA Biomarkers in Early-Stage Non-Small Cell Lung Cancer: A Role for miR-150.

artículo científico publicado en 2017

Quantification of cabazitaxel in human plasma by liquid chromatography/triple-quadrupole mass spectrometry: A practical solution for non-specific binding ⬇️

artículo científico publicado el 24 de octubre de 2011

Quantification of tamoxifen and three of its phase-I metabolites in human plasma by liquid chromatography/triple-quadrupole mass spectrometry ⬇️

artículo científico publicado el 5 de agosto de 2011

Relationship Between Sunitinib Pharmacokinetics and Administration Time: Preclinical and Clinical Evidence.

artículo científico publicado en 2015

Renal function as a predictor of irinotecan-induced neutropenia.

artículo científico publicado en 2008

Reply to Masaki Shiota and Akira Yokomizo's Letter to the Editor re: Robert J. van Soest, Ellen S. de Morrée, Charlotte F. Kweldam, et al. Targeting the Androgen Receptor Confers In Vivo Cross-resistance Between Enzalutamide and Docetaxel, But Not C

artículo científico publicado en 2015

Resistance to platinum-containing chemotherapy in testicular germ cell tumors is associated with downregulation of the protein kinase SRPK1.

artículo científico publicado en 2004

Selection and characterisation of a phage-displayed human antibody (Fab) reactive to the lung resistance-related major vault protein

artículo científico publicado en 2002

Simultaneous quantification of dextromethorphan and its metabolites dextrorphan, 3-methoxymorphinan and 3-hydroxymorphinan in human plasma by ultra performance liquid chromatography/tandem triple-quadrupole mass spectrometry ⬇️

artículo científico publicado el 21 de septiembre de 2010

Stressed tumor cell, chemosensitized cancer ⬇️

artículo científico publicado el 6 de diciembre de 2011

Targeting the Androgen Receptor Confers In Vivo Cross-resistance Between Enzalutamide and Docetaxel, But Not Cabazitaxel, in Castration-resistant Prostate Cancer

artículo científico publicado en 2014

The applicability of mTOR inhibition in solid tumors.

artículo científico publicado en 2009

The electrochemical proton gradient in the bloodstream form of Trypanosoma brucei is dependent on the temperature

artículo científico publicado el 1 de octubre de 1992

The formation of vault-tubes: a dynamic interaction between vaults and vault PARP.

artículo científico publicado en 2003

The genomic sequence of the murine major vault protein and its promoter

artículo científico publicado en 2002

The issue of non-specific binding of cabazitaxel

artículo científico publicado en 2013

The kinase RSK2 modulates the sensitivity of ovarian cancer cells to cisplatin.

artículo científico publicado en 2012

The role of microRNAs in cancer: no small matter.

artículo científico publicado en 2007

The vault complex

artículo científico publicado en 2003

The versatile nature of miR-9/9* in human cancer.

artículo científico publicado en 2018

Tissue-Specific Chk1 Activation Determines Apoptosis by Regulating the Balance of p53 and p21

artículo científico publicado en 2019

Understanding taxanes in prostate cancer; importance of intratumoral drug accumulation.

artículo científico publicado en 2016

Unimpaired dendritic cell functions in MVP/LRP knockout mice

artículo científico publicado en 2003

Unjustified prescribing of CYP2D6 inhibiting SSRIs in women treated with tamoxifen ⬇️

artículo científico publicado el 13 de junio de 2013

Vaults: a ribonucleoprotein particle involved in drug resistance? ⬇️

artículo científico publicado el 20 de octubre de 2003

Visualization of the peroxisomal compartment in living mammalian cells: dynamic behavior and association with microtubules.

artículo científico publicado en 1997

Wnt targets genes are not differentially expressed in desmoid tumors bearing different activating β-catenin mutations

artículo científico publicado en 2018

miR-141 regulates KEAP1 and modulates cisplatin sensitivity in ovarian cancer cells ⬇️

artículo científico publicado el 8 de octubre de 2012

miR-634 restores drug sensitivity in resistant ovarian cancer cells by targeting the Ras-MAPK pathway.

artículo científico publicado en 2015

miRNA expression profiling of 51 human breast cancer cell lines reveals subtype and driver mutation-specific miRNAs

artículo científico publicado en 2013

microRNAs in stage I epithelial ovarian cancer

artículo científico publicado en 2011

Lista de obras de Erik Wiemer

A pharmacogenetic predictive model for paclitaxel clearance based on the DMET platform

A small mammal model of tumour implantation, dissemination and growth factor expression after partial hepatectomy.

Aberrant MicroRNA Expression and Its Implications for Uveal Melanoma Metastasis

Absence of mutations in the deoxycytidine kinase (dCK) gene in patients with relapsed and/or refractory acute myeloid leukemia (AML).

Activated Signaling Pathways and Targeted Therapies in Desmoid-Type Fibromatosis: A Literature Review.

CYP3A4*22 genotype and systemic exposure affect paclitaxel-induced neurotoxicity.

Can "specific" OCT1 inhibitors be used to determine OCT1 transporter activity toward imatinib?

Cell-type-specific role of CHK2 in mediating DNA damage-induced G2 cell cycle arrest

Circadian variation in tamoxifen pharmacokinetics in mice and breast cancer patients.

Cross-resistance between taxanes and new hormonal agents abiraterone and enzalutamide may affect drug sequence choices in metastatic castration-resistant prostate cancer.

DNA damage responsive microRNAs misexpressed in human cancer modulate therapy sensitivity

Deregulated microRNAs in neurofibromatosis type 1 derived malignant peripheral nerve sheath tumors

Dose selection in phase I studies: why we should always go for the top

Early cessation of the clinical development of LiPlaCis, a liposomal cisplatin formulation.

Editorial: the long and winding road to better cancer cell-specific therapies

Effect of omeprazole on the pharmacokinetics and toxicities of irinotecan in cancer patients: a prospective cross-over drug-drug interaction study.

Effects of methimazole on the elimination of irinotecan.

Evaluation of patient enrollment in oncology phase I clinical trials.

Expression and inhibition of BRD4, EZH2 and TOP2A in neurofibromas and malignant peripheral nerve sheath tumors.

Fasting protects against the side effects of irinotecan treatment but does not affect anti-tumour activity in mice

Host resistance to lung infection mediated by major vault protein in epithelial cells

Identification of multidrug resistance-associated protein 1 and glutathione as multidrug resistance mechanisms in human prostate cancer cells: chemosensitization with leukotriene D4 antagonists and buthionine sulfoximine.

Improved insight into resistance mechanisms to imatinib in gastrointestinal stromal tumors: a basis for novel approaches and individualization of treatment

Incident cancer risk after the start of aspirin use: results from a Dutch population-based cohort study of low dose aspirin users

Increased expression of the breast cancer resistance protein (BCRP) in relapsed or refractory acute myeloid leukemia (AML)

Inducible Major Vault Protein Plays a Pivotal Role in Double-Stranded RNA- or Virus-Induced Proinflammatory Response.

Influence of smoking on the pharmacokinetics and toxicity profiles of taxane therapy

Inhibition of activin-like kinase 4/5 attenuates cancer cachexia associated muscle wasting

Isolation and characterization of Pas2p, a peroxisomal membrane protein essential for peroxisome biogenesis in the methylotrophic yeast Pichia pastoris.

Kinetics of the assembly of peroxisomes after fusion of complementary cell lines from patients with the cerebro-hepato-renal (Zellweger) syndrome and related disorders

Loss of E-cadherin is not a necessity for epithelial to mesenchymal transition in human breast cancer.

Loss of SLCO1B3 drives taxane resistance in prostate cancer

MDR1 expression in poor-risk acute myeloid leukemia with partial or complete monosomy 7.

MDR1 gene-related clonal selection and P-glycoprotein function and expression in relapsed or refractory acute myeloid leukemia

Macrocytosis as a potential parameter associated with survival after tyrosine kinase inhibitor treatment.

Major vault protein suppresses obesity and atherosclerosis through inhibiting IKK-NF-κB signaling mediated inflammation

Major vault protein, a candidate gene in 16p11.2 microdeletion syndrome, is required for the homeostatic regulation of visual cortical plasticity.

Major vault protein, in concert with constitutively photomorphogenic 1, negatively regulates c-Jun-mediated activator protein 1 transcription in mammalian cells

MiR-17-92 and miR-221/222 cluster members target KIT and ETV1 in human gastrointestinal stromal tumours

MiR-193b promotes autophagy and non-apoptotic cell death in oesophageal cancer cells

MicroRNA expression and DNA methylation profiles do not distinguish between primary and recurrent well-differentiated liposarcoma

MicroRNA expression profiles distinguish liposarcoma subtypes and implicate miR-145 and miR-451 as tumor suppressors.

MicroRNA markers for forensic body fluid identification obtained from microarray screening and quantitative RT-PCR confirmation

MicroRNA regulation of RAD51 in serous ovarian cancer modulates chemotherapy response

MicroRNA response to hypoxic stress in soft tissue sarcoma cells: microRNA mediated regulation of HIF3α

MicroRNA-mediated gene silencing modulates the UV-induced DNA-damage response

MicroRNAs as possible indicators of drug sensitivity in breast cancer cell lines

MicroRNAs in ovarian cancer biology and therapy resistance.

Multiple human vault RNAs. Expression and association with the vault complex

Non-Coding RNAs, a Novel Paradigm for the Management of Gastrointestinal Stromal Tumors

Phase I pharmacokinetic and pharmacodynamic study of the first-in-class spliceosome inhibitor E7107 in patients with advanced solid tumors.

Phase I study of RGB-286638, a novel, multitargeted cyclin-dependent kinase inhibitor in patients with solid tumors

Phase I study of cisplatin, hyperthermia, and lapatinib in patients with recurrent carcinoma of the uterine cervix in a previously irradiated area

Phenotypic heterogeneity in cultured skin fibroblasts from patients with disorders of peroxisome biogenesis belonging to the same complementation group

Pitfalls of the application of microdialysis in clinical oncology: controversial findings with docetaxel.

Practical aspects of managing gastrointestinal stromal tumors.

Prenatal diagnosis of Zellweger syndrome by direct visualization of peroxisomes in chorionic villus fibroblasts by immunofluorescence microscopy

Production and characterisation of monoclonal antibodies against native and disassembled human catalase

Prognostic Circulating MicroRNA Biomarkers in Early-Stage Non-Small Cell Lung Cancer: A Role for miR-150.

Quantification of cabazitaxel in human plasma by liquid chromatography/triple-quadrupole mass spectrometry: A practical solution for non-specific binding ⬇️

Quantification of tamoxifen and three of its phase-I metabolites in human plasma by liquid chromatography/triple-quadrupole mass spectrometry ⬇️

Relationship Between Sunitinib Pharmacokinetics and Administration Time: Preclinical and Clinical Evidence.

Renal function as a predictor of irinotecan-induced neutropenia.

Reply to Masaki Shiota and Akira Yokomizo's Letter to the Editor re: Robert J. van Soest, Ellen S. de Morrée, Charlotte F. Kweldam, et al. Targeting the Androgen Receptor Confers In Vivo Cross-resistance Between Enzalutamide and Docetaxel, But Not C

Resistance to platinum-containing chemotherapy in testicular germ cell tumors is associated with downregulation of the protein kinase SRPK1.

Selection and characterisation of a phage-displayed human antibody (Fab) reactive to the lung resistance-related major vault protein

Simultaneous quantification of dextromethorphan and its metabolites dextrorphan, 3-methoxymorphinan and 3-hydroxymorphinan in human plasma by ultra performance liquid chromatography/tandem triple-quadrupole mass spectrometry ⬇️

Stressed tumor cell, chemosensitized cancer ⬇️

Targeting the Androgen Receptor Confers In Vivo Cross-resistance Between Enzalutamide and Docetaxel, But Not Cabazitaxel, in Castration-resistant Prostate Cancer

The applicability of mTOR inhibition in solid tumors.

The electrochemical proton gradient in the bloodstream form of Trypanosoma brucei is dependent on the temperature

The formation of vault-tubes: a dynamic interaction between vaults and vault PARP.

The genomic sequence of the murine major vault protein and its promoter

The issue of non-specific binding of cabazitaxel

The kinase RSK2 modulates the sensitivity of ovarian cancer cells to cisplatin.

The role of microRNAs in cancer: no small matter.

The vault complex

The versatile nature of miR-9/9* in human cancer.

Tissue-Specific Chk1 Activation Determines Apoptosis by Regulating the Balance of p53 and p21