Lista de obras - Ugutz Unzueta - Dominio Público Uruguay

A Novel CXCR4-Targeted Diphtheria Toxin Nanoparticle Inhibits Invasion and Metastatic Dissemination in a Head and Neck Squamous Cell Carcinoma Mouse Model

artículo científico publicado en 2022

A multivalent Ara-C-prodrug nanoconjugate achieves selective ablation of leukemic cells in an acute myeloid leukemia mouse model

A nanostructured bacterial bioscaffold for the sustained bottom-up delivery of protein drugs

artículo científico publicado en 2013

A refined cocktailing of pro-apoptotic nanoparticles boosts anti-tumor activity

artículo científico publicado en 2020

An Auristatin nanoconjugate targeting CXCR4+ leukemic cells blocks acute myeloid leukemia dissemination

artículo científico publicado en 2020

Assembly of histidine-rich protein materials controlled through divalent cations

artículo científico publicado en 2018

BBB-targeting, protein-based nanomedicines for drug and nucleic acid delivery to the CNS.

artículo científico publicado en 2015

Bacterial mimetics of endocrine secretory granules as immobilized in vivo depots for functional protein drugs.

artículo científico publicado en 2016

Biofabrication of functional protein nanoparticles through simple His-tag engineering

artículo científico publicado en 2021

Bottom-Up Instructive Quality Control in the Biofabrication of Smart Protein Materials

artículo científico publicado en 2015

CXCR4(+)-targeted protein nanoparticles produced in the food-grade bacterium Lactococcus lactis.

artículo científico publicado en 2016

Cancer-specific uptake of a liganded protein nanocarrier targeting aggressive CXCR4 + colorectal cancer models

artículo científico publicado en 2016

Collaborative membrane activity and receptor-dependent tumor cell targeting for precise nanoparticle delivery in CXCR4+ colorectal cancer

scientific article published on 05 September 2019

Conformational Conversion during Controlled Oligomerization into Nonamylogenic Protein Nanoparticles

scientific article published on 13 August 2018

Conformational and functional variants of CD44-targeted protein nanoparticles bio-produced in bacteria

artículo científico publicado en 2016

Developing Protein-Antitumoral Drug Nanoconjugates as Bifunctional Antimicrobial Agents

artículo científico publicado en 2020

Dialysis: a characterization method of aggregation tendency.

artículo científico publicado en 2015

Efficient bioactive oligonucleotide-protein conjugation for cell-targeted cancer therapy

scientific article published on 28 March 2019

Engineered biological entities for drug delivery and gene therapy protein nanoparticles.

artículo científico

Engineering multifunctional protein nanoparticles by in vitro disassembling and reassembling of heterologous building blocks

artículo científico publicado en 2017

Engineering tumor cell targeting in nanoscale amyloidal materials.

artículo científico publicado en 2016

Fluorescent Dye Labeling Changes the Biodistribution of Tumor-Targeted Nanoparticles

artículo científico publicado en 2020

Functional inclusion bodies produced in the yeast Pichia pastoris.

artículo científico publicado en 2016

Improved performance of protein-based recombinant gene therapy vehicles by tuning downstream procedures

artículo científico publicado en 2013

In vivo architectonic stability of fully de novo designed protein-only nanoparticles

artículo científico publicado en 2014

Internalization and kinetics of nuclear migration of protein-only, arginine-rich nanoparticles.

artículo científico publicado en 2010

Intracellular CXCR4⁺ cell targeting with T22-empowered protein-only nanoparticles.

artículo científico publicado en 2012

Intracellular targeting of CD44+ cells with self-assembling, protein only nanoparticles

artículo científico publicado en 2014

Intracellular trafficking of a dynein-based nanoparticle designed for gene delivery.

artículo científico publicado en 2017

Intrinsic functional and architectonic heterogeneity of tumor-targeted protein nanoparticles

artículo científico publicado en 2017

Lymphocyte infiltration and antitumoral effect promoted by cytotoxic inflammatory proteins formulated as self-assembling, protein-only nanoparticles

Nanoparticulate architecture of protein-based artificial viruses is supported by protein-DNA interactions

artículo científico publicado en 2011

Nanostructured toxins for the selective destruction of drug-resistant human CXCR4+ colorectal cancer stem cells

scientific article published on 10 January 2020

Non-amyloidogenic peptide tags for the regulatable self-assembling of protein-only nanoparticles

artículo científico publicado en 2012

Novel Endometrial Cancer Models Using Sensitive Metastasis Tracing for CXCR4-Targeted Therapy in Advanced Disease

Potent Anticancer Activity of CXCR4-Targeted Nanostructured Toxins in Aggressive Endometrial Cancer Models

Protein aggregation and soluble aggregate formation screened by a fast microdialysis assay

artículo científico publicado en 2010

Protein nanodisk assembling and intracellular trafficking powered by an arginine-rich (R9) peptide

artículo científico publicado en 2010

Protein nanoparticles are nontoxic, tuneable cell stressors

artículo científico publicado en 2018

Protein-Based Therapeutic Killing for Cancer Therapies.

artículo científico publicado en 2017

Protein-driven nanomedicines in oncotherapy.

artículo científico publicado en 2019

Protein-only, antimicrobial peptide-containing recombinant nanoparticles with inherent built-in antibacterial activity.

artículo científico publicado en 2017

RGD-based cell ligands for cell-targeted drug delivery act as potent trophic factors

artículo científico publicado en 2012

Rational engineering of single-chain polypeptides into protein-only, BBB-targeted nanoparticles.

artículo científico publicado en 2016

Recruiting potent membrane penetrability in tumor cell-targeted protein-only nanoparticles

artículo científico publicado en 2018

Rehosting of bacterial chaperones for high-quality protein production.

artículo científico publicado en 2009

Release of targeted protein nanoparticles from functional bacterial amyloids: A death star-like approach.

artículo científico publicado en 2018

Selective CXCR4+ Cancer Cell Targeting and Potent Antineoplastic Effect by a Nanostructured Version of Recombinant Ricin

artículo científico publicado en 2018

Selective delivery of T22-PE24-H6 to CXCR4+ diffuse large B-cell lymphoma cells leads to wide therapeutic index in a disseminated mouse model

scientific article published on 06 April 2020

Selective depletion of metastatic stem cells as therapy for human colorectal cancer

artículo científico publicado en 2018

Self-assembling as regular nanoparticles dramatically minimizes photobleaching of tumour-targeted GFP

scientific article published on 06 December 2019

Self-assembling toxin-based nanoparticles as self-delivered antitumoral drugs.

artículo científico publicado en 2018

Sheltering DNA in self-organizing, protein-only nano-shells as artificial viruses for gene delivery.

artículo científico publicado en 2013

Strategies for the production of difficult-to-express full-length eukaryotic proteins using microbial cell factories: production of human alpha-galactosidase A.

artículo científico publicado en 2015

Structural and functional features of self-assembling protein nanoparticles produced in endotoxin-free Escherichia coli.

artículo científico publicado en 2016

Switching cell penetrating and CXCR4-binding activities of nanoscale-organized arginine-rich peptides.

artículo científico publicado en 2018

The fusogenic peptide HA2 impairs selectivity of CXCR4-targeted protein nanoparticles.

artículo científico publicado en 2017

Topographically targeted osteogenesis of mesenchymal stem cells stimulated by inclusion bodies attached to polycaprolactone surfaces

artículo científico publicado en 2013

Towards protein-based viral mimetics for cancer therapies.

artículo científico publicado en 2015

Lista de obras de Ugutz Unzueta

A Novel CXCR4-Targeted Diphtheria Toxin Nanoparticle Inhibits Invasion and Metastatic Dissemination in a Head and Neck Squamous Cell Carcinoma Mouse Model

A multivalent Ara-C-prodrug nanoconjugate achieves selective ablation of leukemic cells in an acute myeloid leukemia mouse model

A nanostructured bacterial bioscaffold for the sustained bottom-up delivery of protein drugs

A refined cocktailing of pro-apoptotic nanoparticles boosts anti-tumor activity

An Auristatin nanoconjugate targeting CXCR4+ leukemic cells blocks acute myeloid leukemia dissemination

Assembly of histidine-rich protein materials controlled through divalent cations

BBB-targeting, protein-based nanomedicines for drug and nucleic acid delivery to the CNS.

Bacterial mimetics of endocrine secretory granules as immobilized in vivo depots for functional protein drugs.

Biofabrication of functional protein nanoparticles through simple His-tag engineering

Bottom-Up Instructive Quality Control in the Biofabrication of Smart Protein Materials

CXCR4(+)-targeted protein nanoparticles produced in the food-grade bacterium Lactococcus lactis.

Cancer-specific uptake of a liganded protein nanocarrier targeting aggressive CXCR4 + colorectal cancer models

Collaborative membrane activity and receptor-dependent tumor cell targeting for precise nanoparticle delivery in CXCR4+ colorectal cancer

Conformational Conversion during Controlled Oligomerization into Nonamylogenic Protein Nanoparticles

Conformational and functional variants of CD44-targeted protein nanoparticles bio-produced in bacteria

Developing Protein-Antitumoral Drug Nanoconjugates as Bifunctional Antimicrobial Agents

Dialysis: a characterization method of aggregation tendency.

Efficient bioactive oligonucleotide-protein conjugation for cell-targeted cancer therapy

Engineered biological entities for drug delivery and gene therapy protein nanoparticles.

Engineering multifunctional protein nanoparticles by in vitro disassembling and reassembling of heterologous building blocks

Engineering tumor cell targeting in nanoscale amyloidal materials.

Fluorescent Dye Labeling Changes the Biodistribution of Tumor-Targeted Nanoparticles

Functional inclusion bodies produced in the yeast Pichia pastoris.

Improved performance of protein-based recombinant gene therapy vehicles by tuning downstream procedures

In vivo architectonic stability of fully de novo designed protein-only nanoparticles

Internalization and kinetics of nuclear migration of protein-only, arginine-rich nanoparticles.

Intracellular CXCR4⁺ cell targeting with T22-empowered protein-only nanoparticles.

Intracellular targeting of CD44+ cells with self-assembling, protein only nanoparticles

Intracellular trafficking of a dynein-based nanoparticle designed for gene delivery.

Intrinsic functional and architectonic heterogeneity of tumor-targeted protein nanoparticles

Lymphocyte infiltration and antitumoral effect promoted by cytotoxic inflammatory proteins formulated as self-assembling, protein-only nanoparticles

Nanoparticulate architecture of protein-based artificial viruses is supported by protein-DNA interactions

Nanostructured toxins for the selective destruction of drug-resistant human CXCR4+ colorectal cancer stem cells

Non-amyloidogenic peptide tags for the regulatable self-assembling of protein-only nanoparticles

Novel Endometrial Cancer Models Using Sensitive Metastasis Tracing for CXCR4-Targeted Therapy in Advanced Disease

Potent Anticancer Activity of CXCR4-Targeted Nanostructured Toxins in Aggressive Endometrial Cancer Models

Protein aggregation and soluble aggregate formation screened by a fast microdialysis assay

Protein nanodisk assembling and intracellular trafficking powered by an arginine-rich (R9) peptide

Protein nanoparticles are nontoxic, tuneable cell stressors

Protein-Based Therapeutic Killing for Cancer Therapies.

Protein-driven nanomedicines in oncotherapy.

Protein-only, antimicrobial peptide-containing recombinant nanoparticles with inherent built-in antibacterial activity.

RGD-based cell ligands for cell-targeted drug delivery act as potent trophic factors

Rational engineering of single-chain polypeptides into protein-only, BBB-targeted nanoparticles.

Recruiting potent membrane penetrability in tumor cell-targeted protein-only nanoparticles

Rehosting of bacterial chaperones for high-quality protein production.

Release of targeted protein nanoparticles from functional bacterial amyloids: A death star-like approach.

Selective CXCR4+ Cancer Cell Targeting and Potent Antineoplastic Effect by a Nanostructured Version of Recombinant Ricin

Selective delivery of T22-PE24-H6 to CXCR4+ diffuse large B-cell lymphoma cells leads to wide therapeutic index in a disseminated mouse model

Selective depletion of metastatic stem cells as therapy for human colorectal cancer

Self-assembling as regular nanoparticles dramatically minimizes photobleaching of tumour-targeted GFP

Self-assembling toxin-based nanoparticles as self-delivered antitumoral drugs.

Sheltering DNA in self-organizing, protein-only nano-shells as artificial viruses for gene delivery.

Strategies for the production of difficult-to-express full-length eukaryotic proteins using microbial cell factories: production of human alpha-galactosidase A.

Structural and functional features of self-assembling protein nanoparticles produced in endotoxin-free Escherichia coli.

Switching cell penetrating and CXCR4-binding activities of nanoscale-organized arginine-rich peptides.

The fusogenic peptide HA2 impairs selectivity of CXCR4-targeted protein nanoparticles.

Topographically targeted osteogenesis of mesenchymal stem cells stimulated by inclusion bodies attached to polycaprolactone surfaces

Towards protein-based viral mimetics for cancer therapies.