Lista de obras - Sebastian Moran - Dominio Público Uruguay

A Comprehensive DNA Methylation Profile of Epithelial-to-Mesenchymal Transition

scientific article published on 08 August 2014

A DNA methylation map of human cancer at single base-pair resolution.

artículo científico publicado en 2017

A DNA methylation-based definition of biologically distinct breast cancer subtypes

artículo científico publicado en 2014

A Prognostic DNA Methylation Signature for Stage I Non–Small-Cell Lung Cancer

article

A landscape of pharmacogenomic interactions in cancer.

artículo científico publicado en 2016

Aberrant DNA methylation in non-small cell lung cancer-associated fibroblasts

artículo científico publicado en 2015

Aberrant DNA methylation profiles in the premature aging disorders Hutchinson-Gilford Progeria and Werner syndrome

artículo científico publicado en 2012

Arachidonic and oleic acid exert distinct effects on the DNA methylome.

artículo científico publicado en 2016

Caveolin-1 is down-regulated in alveolar rhabdomyosarcomas and negatively regulates tumor growth

artículo científico publicado en 2014

Copy number rather than epigenetic alterations are the major dictator of imprinted methylation in tumors

artículo científico publicado en 2017

Correction to: DNA methylation-based reclassification of olfactory neuroblastoma

artículo científico publicado en 2018

DNA methylation contributes to natural human variation

artículo científico publicado en 2013

DNA methylation dynamics in human carotid plaques after cerebrovascular events

artículo científico publicado en 2015

DNA methylation map of human atherosclerosis

artículo científico publicado en 2014

DNA methylation profiling identifies PTRF/Cavin-1 as a novel tumor suppressor in Ewing sarcoma when co-expressed with caveolin-1.

artículo científico publicado en 2016

DNA methylation profiling in breast cancer discordant identical twins identifies DOK7 as novel epigenetic biomarker

artículo científico publicado en 2012

DNA methylation-based reclassification of olfactory neuroblastoma

artículo científico publicado en 2018

DNMT3A mutations mediate the epigenetic reactivation of the leukemogenic factor MEIS1 in acute myeloid leukemia

artículo científico publicado en 2015

Distinct DNA methylomes of newborns and centenarians

artículo científico publicado en 2012

EGLN2 DNA methylation and expression interact with HIF1A to affect survival of early-stage NSCLC

scientific article published on 31 January 2019

Epigenetic Homogeneity Within Colorectal Tumors Predicts Shorter Relapse-Free and Overall Survival Times for Patients With Locoregional Cancer

artículo científico publicado en 2016

Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFR

artículo científico publicado en 2015

Epigenetic inactivation of the putative DNA/RNA helicase SLFN11 in human cancer confers resistance to platinum drugs

artículo científico publicado en 2015

Epigenetic loss of the RNA decapping enzyme NUDT16 mediates C-MYC activation in T-cell acute lymphoblastic leukemia.

artículo científico publicado en 2017

Epigenetic mechanisms involved in melanoma pathogenesis and chemoresistance

artículo científico publicado en 2015

Epigenetic profiling to classify cancer of unknown primary: a multicentre, retrospective analysis

artículo científico publicado en 2016

Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer.

artículo científico publicado en 2016

Gene amplification of the histone methyltransferase SETDB1 contributes to human lung tumorigenesis

artículo científico publicado en 2013

Gene amplification-associated overexpression of the RNA editing enzyme ADAR1 enhances human lung tumorigenesis

artículo científico publicado en 2016

Genome-wide DNA methylation profiling predicts relapse in childhood B-cell acute lymphoblastic leukaemia

artículo científico publicado en 2012

Genomic Profiling of Patient-Derived Xenografts for Lung Cancer Identifies B2M Inactivation Impairing Immunorecognition

Genomic and Molecular Screenings Identify Different Mechanisms for Acquired Resistance to MET Inhibitors in Lung Cancer Cells

artículo científico publicado en 2017

H3K4me1 marks DNA regions hypomethylated during aging in human stem and differentiated cells

artículo científico publicado en 2014

Higher prevalence of cerebral white matter hyperintensities in homozygous APOE-ɛ4 allele carriers aged 45-75: Results from the ALFA study.

artículo científico publicado en 2017

Human DNA methylomes of neurodegenerative diseases show common epigenomic patterns.

artículo científico publicado en 2016

Identification of 20 novel loci associated with ischaemic stroke. Epigenome-wide association study

artículo científico publicado en 2020

Identification of a new locus and validation of previously reported loci showing differential methylation associated with smoking. The REGICOR study

artículo científico publicado en 2015

Identification of an episignature of human colorectal cancer associated with obesity by genome-wide DNA methylation analysis.

artículo científico publicado en 2018

Journal club: epigenetic profiling to classify cancer of unknown primary - Authors' reply.

artículo científico publicado en 2017

KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer

artículo científico publicado en 2015

Linkage of DNA Methylation Quantitative Trait Loci to Human Cancer Risk

Look-alike humans identified by facial recognition algorithms show genetic similarities

artículo científico publicado en 2022

MAX inactivation in small cell lung cancer disrupts MYC-SWI/SNF programs and is synthetic lethal with BRG1

artículo científico publicado en 2014

Metformin pharmacogenomics: a genome-wide association study to identify genetic and epigenetic biomarkers involved in metformin anticancer response using human lymphoblastoid cell lines

artículo científico publicado en 2016

MicroRNA-654-5p suppresses ovarian cancer development impacting on MYC, WNT and AKT pathways

scientific article published on 05 July 2019

Non-CpG island promoter hypomethylation and miR-149 regulate the expression of SRPX2 in colorectal cancer

artículo científico publicado en 2012

Obesity and menopause modify the epigenomic profile of breast cancer

artículo científico publicado en 2017

Profiling of oxBS-450K 5-hydroxymethylcytosine in human placenta and brain reveals enrichment at imprinted loci.

artículo científico publicado en 2017

Sarcoma classification by DNA methylation profiling

artículo científico publicado en 2021

Sensitization of retinoids and corticoids to epigenetic drugs in MYC-activated lung cancers by antitumor reprogramming.

artículo científico publicado en 2016

Technologies for Deciphering Epigenomic DNA Patterns

artículo científico publicado en 2017

The ALFA project: A research platform to identify early pathophysiological features of Alzheimer's disease

artículo científico publicado en 2016

The DNA methylation drift of the atherosclerotic aorta increases with lesion progression

artículo científico publicado en 2015

The NCI-60 Methylome and Its Integration into CellMiner

artículo científico publicado en 2016

Validation of DNA methylation profiling in formalin-fixed paraffin-embedded samples using the Infinium HumanMethylation450 Microarray.

artículo científico publicado en 2014

Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome

artículo científico publicado en 2011

Validation of a DNA methylation microarray for 850,000 CpG sites of the human genome enriched in enhancer sequences

artículo científico publicado en 2015

Variable maternal methylation overlapping the nc886/vtRNA2-1 locus is locked between hypermethylated repeats and is frequently altered in cancer.

artículo científico publicado en 2014

Whole genome grey and white matter DNA methylation profiles in dorsolateral prefrontal cortex.

artículo científico publicado en 2017

Whole-exome sequencing identifies MDH2 as a new familial paraganglioma gene.

artículo científico publicado en 2015

Whole-genome bisulfite DNA sequencing of a DNMT3B mutant patient

artículo científico publicado en 2012

Lista de obras de Sebastian Moran

A Comprehensive DNA Methylation Profile of Epithelial-to-Mesenchymal Transition

A DNA methylation map of human cancer at single base-pair resolution.

A DNA methylation-based definition of biologically distinct breast cancer subtypes

A Prognostic DNA Methylation Signature for Stage I Non–Small-Cell Lung Cancer

A landscape of pharmacogenomic interactions in cancer.

Aberrant DNA methylation in non-small cell lung cancer-associated fibroblasts

Aberrant DNA methylation profiles in the premature aging disorders Hutchinson-Gilford Progeria and Werner syndrome

Arachidonic and oleic acid exert distinct effects on the DNA methylome.

Caveolin-1 is down-regulated in alveolar rhabdomyosarcomas and negatively regulates tumor growth

Copy number rather than epigenetic alterations are the major dictator of imprinted methylation in tumors

Correction to: DNA methylation-based reclassification of olfactory neuroblastoma

DNA methylation contributes to natural human variation

DNA methylation dynamics in human carotid plaques after cerebrovascular events

DNA methylation map of human atherosclerosis

DNA methylation profiling identifies PTRF/Cavin-1 as a novel tumor suppressor in Ewing sarcoma when co-expressed with caveolin-1.

DNA methylation profiling in breast cancer discordant identical twins identifies DOK7 as novel epigenetic biomarker

DNA methylation-based reclassification of olfactory neuroblastoma

DNMT3A mutations mediate the epigenetic reactivation of the leukemogenic factor MEIS1 in acute myeloid leukemia

Distinct DNA methylomes of newborns and centenarians

EGLN2 DNA methylation and expression interact with HIF1A to affect survival of early-stage NSCLC

Epigenetic Homogeneity Within Colorectal Tumors Predicts Shorter Relapse-Free and Overall Survival Times for Patients With Locoregional Cancer

Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFR

Epigenetic inactivation of the putative DNA/RNA helicase SLFN11 in human cancer confers resistance to platinum drugs

Epigenetic loss of the RNA decapping enzyme NUDT16 mediates C-MYC activation in T-cell acute lymphoblastic leukemia.

Epigenetic mechanisms involved in melanoma pathogenesis and chemoresistance

Epigenetic profiling to classify cancer of unknown primary: a multicentre, retrospective analysis

Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer.

Gene amplification of the histone methyltransferase SETDB1 contributes to human lung tumorigenesis

Gene amplification-associated overexpression of the RNA editing enzyme ADAR1 enhances human lung tumorigenesis

Genome-wide DNA methylation profiling predicts relapse in childhood B-cell acute lymphoblastic leukaemia

Genomic Profiling of Patient-Derived Xenografts for Lung Cancer Identifies B2M Inactivation Impairing Immunorecognition

Genomic and Molecular Screenings Identify Different Mechanisms for Acquired Resistance to MET Inhibitors in Lung Cancer Cells

H3K4me1 marks DNA regions hypomethylated during aging in human stem and differentiated cells

Higher prevalence of cerebral white matter hyperintensities in homozygous APOE-ɛ4 allele carriers aged 45-75: Results from the ALFA study.

Human DNA methylomes of neurodegenerative diseases show common epigenomic patterns.

Identification of 20 novel loci associated with ischaemic stroke. Epigenome-wide association study

Identification of a new locus and validation of previously reported loci showing differential methylation associated with smoking. The REGICOR study

Identification of an episignature of human colorectal cancer associated with obesity by genome-wide DNA methylation analysis.

Journal club: epigenetic profiling to classify cancer of unknown primary - Authors' reply.

KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer

Linkage of DNA Methylation Quantitative Trait Loci to Human Cancer Risk

Look-alike humans identified by facial recognition algorithms show genetic similarities

MAX inactivation in small cell lung cancer disrupts MYC-SWI/SNF programs and is synthetic lethal with BRG1

Metformin pharmacogenomics: a genome-wide association study to identify genetic and epigenetic biomarkers involved in metformin anticancer response using human lymphoblastoid cell lines

MicroRNA-654-5p suppresses ovarian cancer development impacting on MYC, WNT and AKT pathways

Non-CpG island promoter hypomethylation and miR-149 regulate the expression of SRPX2 in colorectal cancer

Obesity and menopause modify the epigenomic profile of breast cancer

Profiling of oxBS-450K 5-hydroxymethylcytosine in human placenta and brain reveals enrichment at imprinted loci.

Sarcoma classification by DNA methylation profiling

Sensitization of retinoids and corticoids to epigenetic drugs in MYC-activated lung cancers by antitumor reprogramming.

Technologies for Deciphering Epigenomic DNA Patterns

The ALFA project: A research platform to identify early pathophysiological features of Alzheimer's disease

The DNA methylation drift of the atherosclerotic aorta increases with lesion progression

The NCI-60 Methylome and Its Integration into CellMiner

Validation of DNA methylation profiling in formalin-fixed paraffin-embedded samples using the Infinium HumanMethylation450 Microarray.

Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome

Validation of a DNA methylation microarray for 850,000 CpG sites of the human genome enriched in enhancer sequences

Variable maternal methylation overlapping the nc886/vtRNA2-1 locus is locked between hypermethylated repeats and is frequently altered in cancer.

Whole genome grey and white matter DNA methylation profiles in dorsolateral prefrontal cortex.

Whole-exome sequencing identifies MDH2 as a new familial paraganglioma gene.

Whole-genome bisulfite DNA sequencing of a DNMT3B mutant patient