Lista de obras - Michelle Peckham - Dominio Público Uruguay

3D Palm Shows Distinct Distributions of Z-Disc Proteins with the Z-Discs in Cardiomyocytes

3Rs and biophysics

artículo científico publicado en 2017

A Combination of Diffusion and Active Translocation Localizes Myosin 10 to the Filopodial Tip ⬇️

artículo científico publicado en 2016

A FERM domain autoregulates Drosophila myosin 7a activity

artículo científico publicado en 2009

A birefringence study of changes in myosin orientation during relaxation of skinned muscle fibers induced by photolytic ATP release

artículo científico publicado en 1994

A call to action from the lab bench

artículo científico publicado en 1997

A targeted deletion of the C-terminal end of titin, including the titin kinase domain, impairs myofibrillogenesis

artículo científico publicado en 2003

A tubulin alpha 8 mouse knockout model indicates a likely role in spermatogenesis but not in brain development. ⬇️

artículo científico publicado en 2017

A1603P and K1617del, Mutations in β-Cardiac Myosin Heavy Chain that Cause Laing Early-Onset Distal Myopathy, Affect Secondary Structure and Filament Formation In Vitro and In Vivo ⬇️

artículo científico publicado en 2018

ANGI-03. THE MIGRATORY SWITCH – INVESTIGATING MESENCHYMAL-AMOEBOID TRANSITION (MAT) IN HIGH GRADE GLIOMAS ⬇️

Actin Mutations and Their Role in Disease

scientific article published on 10 May 2020

Actin filament organization in aligned prefusion myoblasts

artículo científico publicado en 2004

Affimer proteins are versatile and renewable affinity reagents ⬇️

artículo científico publicado en 2017

Affimer proteins for F-actin: novel affinity reagents that label F-actin in live and fixed cells ⬇️

artículo científico publicado en 2018

Alignment of myoblasts on ultrafine gratings inhibits fusion in vitro.

artículo científico publicado en 2002

Alteration in crossbridge kinetics caused by mutations in actin

artículo científico publicado en 1990

Alternative reagents to antibodies in imaging applications ⬇️

artículo científico publicado en 2017

Apolipoprotein(a) acts as a chemorepellent to human vascular smooth muscle cells via integrin αVβ3 and RhoA/ROCK-mediated mechanisms

artículo científico publicado en 2013

Biological and Molecular Approaches to the Generation of Conditionally Immortal Neural Cells

Birefringence as a probe of crossbridge orientation in demembranated muscle fibres

Cardiomyopathy mutations in the tail of β-cardiac myosin modify the coiled-coil structure and affect integration into thick filaments in muscle sarcomeres in adult cardiomyocytes ⬇️

artículo científico publicado en 2013

Cardiomyopathy mutations in the tail of β-cardiac myosin modify the coiled-coil structure and affect integration into thick filaments in muscle sarcomeres in adult cardiomyocytes

artículo científico publicado en 2013

Cell biochemistry studied by single-molecule imaging.

artículo científico publicado en 2006

Chapter 7 The cellular and molecular basis of skeletal and cardiac muscle contraction

Characterization of long and stable de novo single alpha-helix domains provides novel insight into their stability ⬇️

artículo científico publicado en 2017

Coiled coils and SAH domains in cytoskeletal molecular motors ⬇️

artículo científico publicado el 1 de octubre de 2011

Constitutive and variable regions of Z-disk titin/connectin in myofibril formation: a dominant-negative screen

artículo científico publicado en 1997

Construction of an instant structured illumination microscope ⬇️

artículo científico publicado en 2015

Determining How Many Ionic Interactions are Needed for the High Stability of Single Alpha Helical (SAH) Domains

Determining Stable Single Alpha Helical (SAH) Domain Properties by Circular Dichroism and Atomic Force Microscopy

artículo científico publicado en 2018

Different regional effects of voluntary exercise on the mechanical and electrical properties of rat ventricular myocytes

artículo científico publicado en 2002

Differential trafficking of Kif5c on tyrosinated and detyrosinated microtubules in live cells

artículo científico publicado en 2008

Dimerization of mammalian kinesin-3 motors results in superprocessive motion

artículo científico publicado en 2014

Disease mutations in striated muscle myosins

artículo científico publicado en 2020

Dynamic ion pair behavior stabilizes single alpha helices in proteins ⬇️

artículo científico publicado en 2018

Engineering a multi-nucleated myotube, the role of the actin cytoskeleton

artículo científico publicado en 2008

Evidence for differential post-translational modifications of slow myosin heavy chain during murine skeletal muscle development

artículo científico publicado en 2000

Exploiting nanobodies and Affimers for superresolution imaging in light microscopy

artículo científico publicado en 2019

Functional integrity of the contractile actin cortex is safeguarded by multiple Diaphanous-related formins

scientific article published on 11 February 2019

Heterologous expression of wild-type and mutant beta-cardiac myosin changes the contractile kinetics of cultured mouse myotubes

artículo científico publicado en 2003

Heterologous expression of wild-type and mutant beta-cardiac myosin changes the contractile kinetics of cultured mouse myotubes

Histone deacetylase 3 indirectly modulates tubulin acetylation ⬇️

artículo científico publicado en 2015

How myosin organization of the actin cytoskeleton contributes to the cancer phenotype ⬇️

artículo científico publicado en 2016

Human congenital myopathy actin mutants cause myopathy and alter Z-disc structure in Drosophila flight muscle

artículo científico publicado en 2013

Hypertrophic cardiomyopathy mutations in the calponin-homology domain of ACTN2 affect actin binding and cardiomyocyte Z-disc incorporation ⬇️

artículo científico publicado en 2016

Imaging individual myosin molecules within living cells

artículo científico publicado en 2011

Intranuclear rod myopathy: molecular pathogenesis and mechanisms of weakness

artículo científico publicado en 2007

Journal club. A cell biologist ponders an outstanding mystery in muscle formation

artículo científico publicado en 2009

LOX-1 scavenger receptor mediates calcium-dependent recognition of phosphatidylserine and apoptotic cells

artículo científico publicado en 2006

Labile heat and changes in rate of relaxation of frog muscles.

artículo científico publicado en 1986

Local anesthetics inhibit kinesin motility and microtentacle protrusions in human epithelial and breast tumor cells

artículo científico publicado en 2010

Mechanical and Kinetic Properties of a Myosin 5-SAH Chimera

Microtubule assembly in cultured myoblasts and myotubes following nocodazole induced microtubule depolymerisation

artículo científico publicado en 2003

Microtubule proliferation in right ventricular myocytes of rats with monocrotaline-induced pulmonary hypertension

artículo científico publicado en 2012

Modulation of cell spreading and cell-substrate adhesion dynamics by dystroglycan.

artículo científico publicado en 2010

Myogenic cells express multiple myosin isoforms

artículo científico publicado el 1 de octubre de 1997

Myosin crossbridge orientation in demembranated muscle fibres studied by birefringence and X-ray diffraction measurements

scientific article published on 01 November 1989

Myosin tails and single α-helical domains ⬇️

artículo científico publicado en 2015

Myosin-6 Mobility at the Plasma Membrane of Cultured Mammalian Cells

article

N232S, G741R and D778G β-cardiac myosin mutants, implicated in familial hypertrophic cardiomyopathy, do not disrupt myofibrillar organisation in cultured myotubes

artículo científico publicado en 2000

Nanoscale Pattern Extraction from Relative Positions of Sparse 3D Localizations

artículo científico publicado en 2020

Non-muscle myosins 2A and 2B drive changes in cell morphology that occur as myoblasts align and fuse

scientific journal article

Novel murine clonal cell lines either express slow or mixed (fast and slow) muscle markers following differentiation in vitro

artículo científico publicado en 2008

Persistent Chikungunya Virus Replication in Human Cells is Associated with Presence of Stable Cytoplasmic Granules Containing Non-structural Protein 3

Persistent Replication of a Chikungunya Virus Replicon in Human Cells Is Associated with Presence of Stable Cytoplasmic Granules Containing Nonstructural Protein 3 ⬇️

artículo científico publicado en 2018

Physiological properties of the dorsal longitudinal flight muscle and the tergal depressor of the trochanter muscle of Drosophila melanogaster

artículo científico publicado en 1990

Preferential Adhesion to and Survival on Patterned Laminin Organizes Myogenesisin Vitro

artículo científico publicado en 1997

Promoting differentiation of cultured myoblasts using biomimetic surfaces that present alpha-laminin-2 peptides ⬇️

artículo científico publicado en 2016

Recent innovations in super-resolution microscopy

artículo científico publicado en 2015

Single Molecule Investigation of the Acto-Myosin-10 Complex Using Optical Tweezers

Site-Specific Labeling of Affimers for DNA-PAINT Microscopy ⬇️

artículo científico publicado en 2018

Specific Myosins Control Actin Organization, Cell Morphology, and Migration in Prostate Cancer Cells ⬇️

artículo científico publicado en 2015

Specific changes to the mechanism of cell locomotion induced by overexpression of beta-actin.

artículo científico publicado en 2001

Stable single α-helices are constant force springs in proteins ⬇️

artículo científico publicado en 2014

Structural Basis for The Regulation of Drosophila Myosin 7a

Structural Dynamics in the Myosin 7A Single α-Helix Domain

article

Structural implications of β-cardiac myosin heavy chain mutations in human disease

artículo científico publicado en 2014

Structure of the shutdown state of myosin-2

scientific article published on 02 December 2020

TMEM107 recruits ciliopathy proteins to subdomains of the ciliary transition zone and causes Joubert syndrome ⬇️

scientific journal article

Targeted homozygous deletion of M-band titin in cardiomyocytes prevents sarcomere formation

artículo científico publicado en 2006

The Function of Myosin-10 In Vitro and Inside Filopodia

The Inner Centromere Protein (INCENP) Coil Is a Single α-Helix (SAH) Domain That Binds Directly to Microtubules and Is Important for Chromosome Passenger Complex (CPC) Localization and Function in Mitosis. ⬇️

artículo científico publicado en 2015

The SAH domain extends the functional length of the myosin lever ⬇️

artículo científico publicado en 2009

The predicted coiled-coil domain of myosin 10 forms a novel elongated domain that lengthens the head

artículo científico publicado en 2005

The sarcomere length dependence of the rate of heat production during isometric tetanic contraction of frog muscles

article

The spatial and temporal dynamics of pleckstrin homology domain binding at the plasma membrane measured by imaging single molecules in live mouse myoblasts

artículo científico publicado en 2004

Unravelling the Properties of Single α-Helical Domains in Myosin and other Proteins

Using molecular genetics as a tool in understanding crawling cell locomotion in myoblasts.

artículo científico publicado en 1999

Visualisation and analysis of hepatitis C virus non-structural proteins using super-resolution microscopy ⬇️

scientific article published in Scientific Reports

Visualizing single molecules inside living cells using total internal reflection fluorescence microscopy.

artículo científico publicado en 2003

When a predicted coiled coil is really a single α-helix, in myosins and other proteins

article

Lista de obras de Michelle Peckham

3D Palm Shows Distinct Distributions of Z-Disc Proteins with the Z-Discs in Cardiomyocytes

3Rs and biophysics

A Combination of Diffusion and Active Translocation Localizes Myosin 10 to the Filopodial Tip ⬇️

A FERM domain autoregulates Drosophila myosin 7a activity

A birefringence study of changes in myosin orientation during relaxation of skinned muscle fibers induced by photolytic ATP release

A call to action from the lab bench

A targeted deletion of the C-terminal end of titin, including the titin kinase domain, impairs myofibrillogenesis

A tubulin alpha 8 mouse knockout model indicates a likely role in spermatogenesis but not in brain development. ⬇️

A1603P and K1617del, Mutations in β-Cardiac Myosin Heavy Chain that Cause Laing Early-Onset Distal Myopathy, Affect Secondary Structure and Filament Formation In Vitro and In Vivo ⬇️

ANGI-03. THE MIGRATORY SWITCH – INVESTIGATING MESENCHYMAL-AMOEBOID TRANSITION (MAT) IN HIGH GRADE GLIOMAS ⬇️

Actin Mutations and Their Role in Disease

Actin filament organization in aligned prefusion myoblasts

Affimer proteins are versatile and renewable affinity reagents ⬇️

Affimer proteins for F-actin: novel affinity reagents that label F-actin in live and fixed cells ⬇️

Alignment of myoblasts on ultrafine gratings inhibits fusion in vitro.

Alteration in crossbridge kinetics caused by mutations in actin

Alternative reagents to antibodies in imaging applications ⬇️

Apolipoprotein(a) acts as a chemorepellent to human vascular smooth muscle cells via integrin αVβ3 and RhoA/ROCK-mediated mechanisms

Biological and Molecular Approaches to the Generation of Conditionally Immortal Neural Cells

Birefringence as a probe of crossbridge orientation in demembranated muscle fibres

Cardiomyopathy mutations in the tail of β-cardiac myosin modify the coiled-coil structure and affect integration into thick filaments in muscle sarcomeres in adult cardiomyocytes ⬇️

Cardiomyopathy mutations in the tail of β-cardiac myosin modify the coiled-coil structure and affect integration into thick filaments in muscle sarcomeres in adult cardiomyocytes

Cell biochemistry studied by single-molecule imaging.

Chapter 7 The cellular and molecular basis of skeletal and cardiac muscle contraction

Characterization of long and stable de novo single alpha-helix domains provides novel insight into their stability ⬇️

Coiled coils and SAH domains in cytoskeletal molecular motors ⬇️

Constitutive and variable regions of Z-disk titin/connectin in myofibril formation: a dominant-negative screen

Construction of an instant structured illumination microscope ⬇️

Determining How Many Ionic Interactions are Needed for the High Stability of Single Alpha Helical (SAH) Domains

Determining Stable Single Alpha Helical (SAH) Domain Properties by Circular Dichroism and Atomic Force Microscopy

Different regional effects of voluntary exercise on the mechanical and electrical properties of rat ventricular myocytes

Differential trafficking of Kif5c on tyrosinated and detyrosinated microtubules in live cells

Dimerization of mammalian kinesin-3 motors results in superprocessive motion

Disease mutations in striated muscle myosins

Dynamic ion pair behavior stabilizes single alpha helices in proteins ⬇️

Engineering a multi-nucleated myotube, the role of the actin cytoskeleton

Evidence for differential post-translational modifications of slow myosin heavy chain during murine skeletal muscle development

Exploiting nanobodies and Affimers for superresolution imaging in light microscopy

Functional integrity of the contractile actin cortex is safeguarded by multiple Diaphanous-related formins

Heterologous expression of wild-type and mutant beta-cardiac myosin changes the contractile kinetics of cultured mouse myotubes

Heterologous expression of wild-type and mutant beta-cardiac myosin changes the contractile kinetics of cultured mouse myotubes

Histone deacetylase 3 indirectly modulates tubulin acetylation ⬇️

How myosin organization of the actin cytoskeleton contributes to the cancer phenotype ⬇️

Human congenital myopathy actin mutants cause myopathy and alter Z-disc structure in Drosophila flight muscle

Hypertrophic cardiomyopathy mutations in the calponin-homology domain of ACTN2 affect actin binding and cardiomyocyte Z-disc incorporation ⬇️

Imaging individual myosin molecules within living cells

Intranuclear rod myopathy: molecular pathogenesis and mechanisms of weakness

Journal club. A cell biologist ponders an outstanding mystery in muscle formation

LOX-1 scavenger receptor mediates calcium-dependent recognition of phosphatidylserine and apoptotic cells

Labile heat and changes in rate of relaxation of frog muscles.

Local anesthetics inhibit kinesin motility and microtentacle protrusions in human epithelial and breast tumor cells

Mechanical and Kinetic Properties of a Myosin 5-SAH Chimera

Microtubule assembly in cultured myoblasts and myotubes following nocodazole induced microtubule depolymerisation

Microtubule proliferation in right ventricular myocytes of rats with monocrotaline-induced pulmonary hypertension

Modulation of cell spreading and cell-substrate adhesion dynamics by dystroglycan.

Myogenic cells express multiple myosin isoforms

Myosin crossbridge orientation in demembranated muscle fibres studied by birefringence and X-ray diffraction measurements

Myosin tails and single α-helical domains ⬇️

Myosin-6 Mobility at the Plasma Membrane of Cultured Mammalian Cells

N232S, G741R and D778G β-cardiac myosin mutants, implicated in familial hypertrophic cardiomyopathy, do not disrupt myofibrillar organisation in cultured myotubes

Nanoscale Pattern Extraction from Relative Positions of Sparse 3D Localizations

Non-muscle myosins 2A and 2B drive changes in cell morphology that occur as myoblasts align and fuse

Novel murine clonal cell lines either express slow or mixed (fast and slow) muscle markers following differentiation in vitro

Persistent Chikungunya Virus Replication in Human Cells is Associated with Presence of Stable Cytoplasmic Granules Containing Non-structural Protein 3

Persistent Replication of a Chikungunya Virus Replicon in Human Cells Is Associated with Presence of Stable Cytoplasmic Granules Containing Nonstructural Protein 3 ⬇️

Physiological properties of the dorsal longitudinal flight muscle and the tergal depressor of the trochanter muscle of Drosophila melanogaster

Preferential Adhesion to and Survival on Patterned Laminin Organizes Myogenesisin Vitro

Promoting differentiation of cultured myoblasts using biomimetic surfaces that present alpha-laminin-2 peptides ⬇️

Recent innovations in super-resolution microscopy

Single Molecule Investigation of the Acto-Myosin-10 Complex Using Optical Tweezers

Site-Specific Labeling of Affimers for DNA-PAINT Microscopy ⬇️

Specific Myosins Control Actin Organization, Cell Morphology, and Migration in Prostate Cancer Cells ⬇️

Specific changes to the mechanism of cell locomotion induced by overexpression of beta-actin.

Stable single α-helices are constant force springs in proteins ⬇️

Structural Basis for The Regulation of Drosophila Myosin 7a

Structural Dynamics in the Myosin 7A Single α-Helix Domain

Structural implications of β-cardiac myosin heavy chain mutations in human disease

Structure of the shutdown state of myosin-2

TMEM107 recruits ciliopathy proteins to subdomains of the ciliary transition zone and causes Joubert syndrome ⬇️