Lista de obras - Helen R. Mott - Dominio Público Uruguay

(1)H, (13)C and (15)N resonance assignments of the Cdc42-binding domain of TOCA1

artículo científico publicado en 2016

1H, 13C and 15N resonance assignments for Binder of Arl2, BART.

artículo científico publicado en 2008

1H, 13C and 15N resonance assignments for the active conformation of the small G protein RalB in complex with its effector RLIP76.

artículo científico publicado en 2008

1H, 13C and 15N resonance assignments for the small G protein RalB in its active conformation.

artículo científico publicado en 2007

1H, 13C and 15N resonance assignments of the GTPase-activating (GAP) and Ral binding domains (GBD) of RLIP76 (RalBP1).

artículo científico publicado en 2011

1H, 15N and 13C resonance assignments of the HR1c domain of PRK1, a protein kinase C-related kinase

scientific article published on 04 June 2020

A Complete Survey of RhoGDI Targets Reveals Novel Interactions with Atypical Small GTPases

artículo científico publicado en 2021

A dock and coalesce mechanism driven by hydrophobic interactions governs Cdc42 binding with its effector protein ACK

artículo científico publicado en 2017

Affinity maturation of the RLIP76 Ral binding domain to inform the design of stapled peptides targeting the Ral GTPases

artículo científico publicado en 2020

Atomic structure and hierarchical assembly of a cross- amyloid fibril

artículo científico publicado en 2013

Bioblockades join the assault on small G protein signalling.

artículo científico publicado en 2018

Cdc42 in actin dynamics: An ordered pathway governed by complex equilibria and directional effector handover

artículo científico publicado en 2016

Differential binding of RhoA, RhoB, and RhoC to protein kinase C-related kinase (PRK) isoforms PRK1, PRK2, and PRK3: PRKs have the highest affinity for RhoB.

artículo científico publicado en 2013

Double mutant cycle thermodynamic analysis of the hydrophobic Cdc42-ACK protein-protein interaction

artículo científico publicado en 2007

Erratum to: (1)H, (13)C and (15)N resonance assignments of the Cdc42-binding domain of TOCA1.

artículo científico publicado en 2016

Fluorescence properties of green fluorescent protein FRET pairs concatenated with the small G protein, Rac, and its interacting domain of the kinase, p21-activated kinase

artículo científico publicado en 2004

Genomic Subtypes of Non-invasive Bladder Cancer with Distinct Metabolic Profile and Female Gender Bias in KDM6A Mutation Frequency ⬇️

artículo científico publicado en 2017

Human interleukin-1 receptor antagonist. High yield expression in E. coli and examination of cysteine residues

artículo científico publicado el 21 de septiembre de 1992

Hydrodynamic gene delivery of baboon trypanosome lytic factor eliminates both animal and human-infective African trypanosomes

artículo científico publicado en 2009

In support of the BMRB.

artículo científico publicado en 2012

Inhibition of Ral GTPases Using a Stapled Peptide Approach.

artículo científico publicado en 2016

Integral membrane protein structure determination using pseudocontact shifts.

artículo científico publicado en 2015

Investigation of the Interaction between Cdc42 and Its Effector TOCA1: HANDOVER OF Cdc42 TO THE ACTIN REGULATOR N-WASP IS FACILITATED BY DIFFERENTIAL BINDING AFFINITIES.

artículo científico publicado en 2016

Molecular dissection of the interaction between the small G proteins Rac1 and RhoA and protein kinase C-related kinase 1 (PRK1)

artículo científico publicado en 2003

Mutational analysis reveals a single binding interface between RhoA and its effector, PRK1.

artículo científico publicado en 2011

NMR Analysis of Interacting Soluble Forms of the Cell−Cell Recognition Molecules CD2 and CD48†

article

NMR resonance assignments for the active and inactive conformations of the small G protein RalA

scientific article published on 08 January 2020

RLIP76 (RalBP1): The first piece of the structural puzzle

artículo científico publicado en 2010

Resonance assignments for the RLIP76 Ral binding domain in its free form and in complex with the small G protein RalB.

artículo científico publicado en 2008

Role of intermolecular forces in defining material properties of protein nanofibrils

artículo científico publicado en 2007

Secondary structure of human interleukin 2 from 3D heteronuclear NMR experiments

artículo científico publicado el 25 de agosto de 1992

Solution structure and dynamics of the small GTPase RalB in its active conformation: significance for effector protein binding

artículo científico publicado en 2009

Specificity determinants on Cdc42 for binding its effector protein ACK.

artículo científico publicado en 2005

Structural analysis of the SH3 domain of beta-PIX and its interaction with alpha-p21 activated kinase (PAK)

artículo científico publicado en 2005

Structural and Functional Analysis of a Mutant Ras Protein That Is Insensitive to Nitric Oxide Activation†

article

Structural basis for the shielding function of the dynamic trypanosome variant surface glycoprotein coat

artículo científico publicado en 2017

Structural basis of HP1/PXVXL motif peptide interactions and HP1 localisation to heterochromatin

artículo científico publicado en 2004

Structure and function of RLIP76 (RalBP1): an intersection point between Ras and Rho signalling

artículo científico publicado en 2014

Structure determination of the seven-helix transmembrane receptor sensory rhodopsin II by solution NMR spectroscopy

artículo científico publicado en 2010

Structure of a glycosylphosphatidylinositol-anchored domain from a trypanosome variant surface glycoprotein

artículo científico publicado en 2008

Structure of the C-terminal domain from Trypanosoma brucei variant surface glycoprotein MITat1.2.

artículo científico publicado en 2004

Structure of the GTPase-binding domain of Sec5 and elucidation of its Ral binding site

artículo científico publicado en 2003

Structure of the HP1 chromodomain bound to histone H3 methylated at lysine 9

artículo científico publicado en 2002

Structure of the small G protein Cdc42 bound to the GTPase-binding domain of ACK

artículo científico publicado en 1999

Structure of the sterile alpha motif (SAM) domain of the Saccharomyces cerevisiae mitogen-activated protein kinase pathway-modulating protein STE50 and analysis of its interaction with the STE11 SAM

artículo científico publicado en 2004

Structures of Ras superfamily effector complexes: What have we learnt in two decades?

artículo científico

The IQGAP1-Rac1 and IQGAP1-Cdc42 interactions: interfaces differ between the complexes

artículo científico publicado en 2007

The Rac1 polybasic region is required for interaction with its effector PRK1

artículo científico publicado en 2008

The RalB-RLIP76 Complex Reveals a Novel Mode of Ral-Effector Interaction

artículo científico publicado en 2010

The Structure of the RLIP76 RhoGAP-Ral Binding Domain Dyad: Fixed Position of the Domains Leads to Dual Engagement of Small G Proteins at the Membrane

artículo científico publicado en 2013

The discovery and maturation of peptide biologics targeting the small G-protein Cdc42: A bioblockade for Ras-driven signaling

scientific article published on 20 January 2020

The solution structure of the Raf-1 cysteine-rich domain: a novel ras and phospholipid binding site

artículo científico publicado en 1996

The structure of binder of Arl2 (BART) reveals a novel G protein binding domain: implications for function

artículo científico publicado en 2009

Thermodynamic mapping of effector protein interfaces with RalA and RalB.

artículo científico publicado en 2015

Variant Surface Glycoprotein gene repertoires in Trypanosoma brucei have diverged to become strain-specific

artículo científico publicado en 2007

Lista de obras de Helen R. Mott

(1)H, (13)C and (15)N resonance assignments of the Cdc42-binding domain of TOCA1

1H, 13C and 15N resonance assignments for Binder of Arl2, BART.

1H, 13C and 15N resonance assignments for the active conformation of the small G protein RalB in complex with its effector RLIP76.

1H, 13C and 15N resonance assignments for the small G protein RalB in its active conformation.

1H, 13C and 15N resonance assignments of the GTPase-activating (GAP) and Ral binding domains (GBD) of RLIP76 (RalBP1).

1H, 15N and 13C resonance assignments of the HR1c domain of PRK1, a protein kinase C-related kinase

A Complete Survey of RhoGDI Targets Reveals Novel Interactions with Atypical Small GTPases

A dock and coalesce mechanism driven by hydrophobic interactions governs Cdc42 binding with its effector protein ACK

Affinity maturation of the RLIP76 Ral binding domain to inform the design of stapled peptides targeting the Ral GTPases

Atomic structure and hierarchical assembly of a cross- amyloid fibril

Bioblockades join the assault on small G protein signalling.

Cdc42 in actin dynamics: An ordered pathway governed by complex equilibria and directional effector handover

Differential binding of RhoA, RhoB, and RhoC to protein kinase C-related kinase (PRK) isoforms PRK1, PRK2, and PRK3: PRKs have the highest affinity for RhoB.

Double mutant cycle thermodynamic analysis of the hydrophobic Cdc42-ACK protein-protein interaction

Erratum to: (1)H, (13)C and (15)N resonance assignments of the Cdc42-binding domain of TOCA1.

Fluorescence properties of green fluorescent protein FRET pairs concatenated with the small G protein, Rac, and its interacting domain of the kinase, p21-activated kinase

Genomic Subtypes of Non-invasive Bladder Cancer with Distinct Metabolic Profile and Female Gender Bias in KDM6A Mutation Frequency ⬇️

Human interleukin-1 receptor antagonist. High yield expression in E. coli and examination of cysteine residues

Hydrodynamic gene delivery of baboon trypanosome lytic factor eliminates both animal and human-infective African trypanosomes

In support of the BMRB.

Inhibition of Ral GTPases Using a Stapled Peptide Approach.

Integral membrane protein structure determination using pseudocontact shifts.

Investigation of the Interaction between Cdc42 and Its Effector TOCA1: HANDOVER OF Cdc42 TO THE ACTIN REGULATOR N-WASP IS FACILITATED BY DIFFERENTIAL BINDING AFFINITIES.

Molecular dissection of the interaction between the small G proteins Rac1 and RhoA and protein kinase C-related kinase 1 (PRK1)

Mutational analysis reveals a single binding interface between RhoA and its effector, PRK1.

NMR Analysis of Interacting Soluble Forms of the Cell−Cell Recognition Molecules CD2 and CD48†

NMR resonance assignments for the active and inactive conformations of the small G protein RalA

RLIP76 (RalBP1): The first piece of the structural puzzle

Resonance assignments for the RLIP76 Ral binding domain in its free form and in complex with the small G protein RalB.

Role of intermolecular forces in defining material properties of protein nanofibrils

Secondary structure of human interleukin 2 from 3D heteronuclear NMR experiments

Solution structure and dynamics of the small GTPase RalB in its active conformation: significance for effector protein binding

Specificity determinants on Cdc42 for binding its effector protein ACK.

Structural analysis of the SH3 domain of beta-PIX and its interaction with alpha-p21 activated kinase (PAK)

Structural and Functional Analysis of a Mutant Ras Protein That Is Insensitive to Nitric Oxide Activation†

Structural basis for the shielding function of the dynamic trypanosome variant surface glycoprotein coat

Structural basis of HP1/PXVXL motif peptide interactions and HP1 localisation to heterochromatin

Structure and function of RLIP76 (RalBP1): an intersection point between Ras and Rho signalling

Structure determination of the seven-helix transmembrane receptor sensory rhodopsin II by solution NMR spectroscopy

Structure of a glycosylphosphatidylinositol-anchored domain from a trypanosome variant surface glycoprotein

Structure of the C-terminal domain from Trypanosoma brucei variant surface glycoprotein MITat1.2.

Structure of the GTPase-binding domain of Sec5 and elucidation of its Ral binding site

Structure of the HP1 chromodomain bound to histone H3 methylated at lysine 9

Structure of the small G protein Cdc42 bound to the GTPase-binding domain of ACK

Structure of the sterile alpha motif (SAM) domain of the Saccharomyces cerevisiae mitogen-activated protein kinase pathway-modulating protein STE50 and analysis of its interaction with the STE11 SAM

Structures of Ras superfamily effector complexes: What have we learnt in two decades?

The IQGAP1-Rac1 and IQGAP1-Cdc42 interactions: interfaces differ between the complexes

The Rac1 polybasic region is required for interaction with its effector PRK1

The RalB-RLIP76 Complex Reveals a Novel Mode of Ral-Effector Interaction

The Structure of the RLIP76 RhoGAP-Ral Binding Domain Dyad: Fixed Position of the Domains Leads to Dual Engagement of Small G Proteins at the Membrane

The discovery and maturation of peptide biologics targeting the small G-protein Cdc42: A bioblockade for Ras-driven signaling

The solution structure of the Raf-1 cysteine-rich domain: a novel ras and phospholipid binding site

The structure of binder of Arl2 (BART) reveals a novel G protein binding domain: implications for function

Thermodynamic mapping of effector protein interfaces with RalA and RalB.

Variant Surface Glycoprotein gene repertoires in Trypanosoma brucei have diverged to become strain-specific