Lista de obras - Georg Meisl - Dominio Público Uruguay

A method of predicting the in vitro fibril formation propensity of Aβ40 mutants based on their inclusion body levels in E. coli

artículo científico publicado en 2019

A microfluidic diffusion platform for characterizing the size of lipid vesicles and the thermodynamics of protein-lipid interactions.

artículo científico publicado en 2018

A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity

artículo científico publicado en 2017

Absolute Quantification of Amyloid Propagons by Digital Microfluidics

artículo científico publicado en 2017

An Environmentally Sensitive Fluorescent Dye as a Multidimensional Probe of Amyloid Formation

artículo científico publicado en 2016

Author Correction: Dynamics of oligomer populations formed during the aggregation of Alzheimer's Aβ42 peptide

artículo científico publicado en 2020

Autoantibodies against the prion protein in individuals with PRNP mutations

artículo científico publicado en 2020

Autocatalytic amplification of Alzheimer-associated Aβ42 peptide aggregation in human cerebrospinal fluid

scientific article published on 08 October 2019

Differences in nucleation behavior underlie the contrasting aggregation kinetics of the Aβ40 and Aβ42 peptides

artículo científico publicado en 2014

Diffuse transition state structure for the unfolding of a leucine-rich repeat protein.

artículo científico publicado en 2014

Direct observation of murine prion protein replication in vitro

artículo científico publicado en 2018

Direct observation of prion protein oligomer formation reveals an aggregation mechanism with multiple conformationally distinct species

artículo científico publicado en 2019

Dynamics of oligomer populations formed during the aggregation of Alzheimer's Aβ42 peptide

artículo científico publicado en 2020

Electrostatically-guided inhibition of Curli amyloid nucleation by the CsgC-like family of chaperones

artículo científico publicado en 2016

Extrinsic Amyloid-Binding Dyes for Detection of Individual Protein Aggregates in Solution

scholarly article by Christopher G Taylor et al published 4 September 2018 in Analytical Chemistry

Identification of on- and off-pathway oligomers in amyloid fibril formation

scientific article published on 08 June 2020

Increased Secondary Nucleation Underlies Accelerated Aggregation of the Four-Residue N-Terminally Truncated Aβ42 Species Aβ5-42

scientific article published on 08 March 2019

Kinetic analysis reveals that independent nucleation events determine the progression of polyglutamine aggregation in <i>C. elegans</i>

artículo científico publicado en 2021

Kinetic barriers to α-synuclein protofilament formation and conversion into mature fibrils

artículo científico publicado en 2018

Kinetic diversity of amyloid oligomers

scientific article published on 15 May 2020

Kinetic fingerprints differentiate the mechanisms of action of anti-Aβ antibodies

artículo científico publicado en 2020

Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation

artículo científico publicado en 2015

Measurement of Tau Filament Fragmentation Provides Insights into Prion-like Spreading.

artículo científico publicado en 2018

Mechanism of Fibril and Soluble Oligomer Formation in Amyloid Beta and Hen Egg White Lysozyme Proteins

scientific article published on 27 June 2019

Microfluidic Antibody Affinity Profiling Reveals the Role of Memory Reactivation and Cross-Reactivity in the Defense Against SARS-CoV-2

artículo científico publicado en 2022

Modulation of electrostatic interactions to reveal a reaction network unifying the aggregation behaviour of the Aβ42 peptide and its variants

artículo científico publicado en 2017

Molecular mechanisms of protein aggregation from global fitting of kinetic models.

artículo científico publicado en 2016

Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine

article

Mutations associated with familial Parkinson's disease alter the initiation and amplification steps of α-synuclein aggregation

artículo científico publicado en 2016

N-Terminal Extensions Retard Aβ42 Fibril Formation but Allow Cross-Seeding and Coaggregation with Aβ42

artículo científico publicado en 2015

Oligomer Diversity during the Aggregation of the Repeat Region of Tau

scientific article published on 17 July 2018

On the role of sidechain size and charge in the aggregation of A42 with familial mutations

article published in the Proceedings of the National Academy of Sciences of the United States of America

On-chip measurements of protein unfolding from direct observations of micron-scale diffusion.

artículo científico publicado en 2018

Origin of metastable oligomers and their effects on amyloid fibril self-assembly

scientific article published on 13 June 2018

Ostwald's rule of stages governs structural transitions and morphology of dipeptide supramolecular polymers

artículo científico publicado en 2014

Phage display and kinetic selection of antibodies that specifically inhibit amyloid self-replication ⬇️

artículo científico publicado en 2017

Physical determinants of the self-replication of protein fibrils

scientific article published on 18 July 2016

Plant Polyphenols Inhibit Functional Amyloid and Biofilm Formation in Pseudomonas Strains by Directing Monomers to Off-Pathway Oligomers

artículo científico publicado en 2019

Preventing peptide and protein misbehavior.

artículo científico publicado en 2015

Pulsed Hydrogen-Deuterium Exchange Reveals Altered Structures and Mechanisms in the Aggregation of Familial Alzheimer's Disease Mutants

artículo científico publicado en 2021

Quantitative analysis of intrinsic and extrinsic factors in the aggregation mechanism of Alzheimer-associated Aβ-peptide

artículo científico publicado en 2016

Scaling behaviour and rate-determining steps in filamentous self-assembly

artículo científico publicado en 2017

Secondary nucleation in amyloid formation

artículo científico publicado en 2018

Self-assembly of MPG1, a hydrophobin protein from the rice blast fungus that forms functional amyloid coatings, occurs by a surface-driven mechanism

artículo científico publicado en 2016

Solvent and conformation dependence of amide I vibrations in peptides and proteins containing proline

artículo científico publicado en 2011

Super-resolution imaging reveals α-synuclein seeded aggregation in SH-SY5Y cells

artículo científico publicado en 2021

The Aβ40 and Aβ42 peptides self-assemble into separate homomolecular fibrils in binary mixtures but cross-react during primary nucleation.

artículo científico publicado en 2015

The Influence of Pathogenic Mutations in α-Synuclein on Biophysical and Structural Characteristics of Amyloid Fibrils

scientific article published on 17 March 2020

The catalytic nature of protein aggregation

artículo científico publicado en 2020

The molecular processes underpinning prion-like spreading and seed amplification in protein aggregation

artículo científico publicado en 2020

The role of fibril structure and surface hydrophobicity in secondary nucleation of amyloid fibrils

scientific article published on 01 October 2020

Thermodynamic and kinetic design principles for amyloid-aggregation inhibitors

scientific article published on 14 September 2020

Transthyretin Inhibits Primary and Secondary Nucleations of Amyloid-β Peptide Aggregation and Reduces the Toxicity of Its Oligomers

artículo científico publicado en 2020

Trodusquemine enhances Aβ aggregation but suppresses its toxicity by displacing oligomers from cell membranes

scientific article published in Nature Communications

Ultrastructural evidence for self-replication of Alzheimer-associated Aβ42 amyloid along the sides of fibrils

scientific article published on 21 May 2020

α-Synuclein strains target distinct brain regions and cell types

scientific article published on 02 December 2019

Lista de obras de Georg Meisl

A method of predicting the in vitro fibril formation propensity of Aβ40 mutants based on their inclusion body levels in E. coli

A microfluidic diffusion platform for characterizing the size of lipid vesicles and the thermodynamics of protein-lipid interactions.

A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity

Absolute Quantification of Amyloid Propagons by Digital Microfluidics

An Environmentally Sensitive Fluorescent Dye as a Multidimensional Probe of Amyloid Formation

Author Correction: Dynamics of oligomer populations formed during the aggregation of Alzheimer's Aβ42 peptide

Autoantibodies against the prion protein in individuals with PRNP mutations

Autocatalytic amplification of Alzheimer-associated Aβ42 peptide aggregation in human cerebrospinal fluid

Differences in nucleation behavior underlie the contrasting aggregation kinetics of the Aβ40 and Aβ42 peptides

Diffuse transition state structure for the unfolding of a leucine-rich repeat protein.

Direct observation of murine prion protein replication in vitro

Direct observation of prion protein oligomer formation reveals an aggregation mechanism with multiple conformationally distinct species

Dynamics of oligomer populations formed during the aggregation of Alzheimer's Aβ42 peptide

Electrostatically-guided inhibition of Curli amyloid nucleation by the CsgC-like family of chaperones

Extrinsic Amyloid-Binding Dyes for Detection of Individual Protein Aggregates in Solution

Identification of on- and off-pathway oligomers in amyloid fibril formation

Increased Secondary Nucleation Underlies Accelerated Aggregation of the Four-Residue N-Terminally Truncated Aβ42 Species Aβ5-42

Kinetic analysis reveals that independent nucleation events determine the progression of polyglutamine aggregation in <i>C. elegans</i>

Kinetic barriers to α-synuclein protofilament formation and conversion into mature fibrils

Kinetic diversity of amyloid oligomers

Kinetic fingerprints differentiate the mechanisms of action of anti-Aβ antibodies

Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation

Measurement of Tau Filament Fragmentation Provides Insights into Prion-like Spreading.

Mechanism of Fibril and Soluble Oligomer Formation in Amyloid Beta and Hen Egg White Lysozyme Proteins

Microfluidic Antibody Affinity Profiling Reveals the Role of Memory Reactivation and Cross-Reactivity in the Defense Against SARS-CoV-2

Modulation of electrostatic interactions to reveal a reaction network unifying the aggregation behaviour of the Aβ42 peptide and its variants

Molecular mechanisms of protein aggregation from global fitting of kinetic models.

Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine

Mutations associated with familial Parkinson's disease alter the initiation and amplification steps of α-synuclein aggregation

N-Terminal Extensions Retard Aβ42 Fibril Formation but Allow Cross-Seeding and Coaggregation with Aβ42

Oligomer Diversity during the Aggregation of the Repeat Region of Tau

On the role of sidechain size and charge in the aggregation of A42 with familial mutations

On-chip measurements of protein unfolding from direct observations of micron-scale diffusion.

Origin of metastable oligomers and their effects on amyloid fibril self-assembly

Ostwald's rule of stages governs structural transitions and morphology of dipeptide supramolecular polymers

Phage display and kinetic selection of antibodies that specifically inhibit amyloid self-replication ⬇️

Physical determinants of the self-replication of protein fibrils

Plant Polyphenols Inhibit Functional Amyloid and Biofilm Formation in Pseudomonas Strains by Directing Monomers to Off-Pathway Oligomers

Preventing peptide and protein misbehavior.

Pulsed Hydrogen-Deuterium Exchange Reveals Altered Structures and Mechanisms in the Aggregation of Familial Alzheimer's Disease Mutants

Quantitative analysis of intrinsic and extrinsic factors in the aggregation mechanism of Alzheimer-associated Aβ-peptide

Scaling behaviour and rate-determining steps in filamentous self-assembly

Secondary nucleation in amyloid formation

Self-assembly of MPG1, a hydrophobin protein from the rice blast fungus that forms functional amyloid coatings, occurs by a surface-driven mechanism

Solvent and conformation dependence of amide I vibrations in peptides and proteins containing proline

Super-resolution imaging reveals α-synuclein seeded aggregation in SH-SY5Y cells

The Aβ40 and Aβ42 peptides self-assemble into separate homomolecular fibrils in binary mixtures but cross-react during primary nucleation.

The Influence of Pathogenic Mutations in α-Synuclein on Biophysical and Structural Characteristics of Amyloid Fibrils

The catalytic nature of protein aggregation

The molecular processes underpinning prion-like spreading and seed amplification in protein aggregation

The role of fibril structure and surface hydrophobicity in secondary nucleation of amyloid fibrils

Thermodynamic and kinetic design principles for amyloid-aggregation inhibitors

Transthyretin Inhibits Primary and Secondary Nucleations of Amyloid-β Peptide Aggregation and Reduces the Toxicity of Its Oligomers

Trodusquemine enhances Aβ aggregation but suppresses its toxicity by displacing oligomers from cell membranes

Ultrastructural evidence for self-replication of Alzheimer-associated Aβ42 amyloid along the sides of fibrils

α-Synuclein strains target distinct brain regions and cell types