Lista de obras - Lars Hemmingsen - Dominio Público Uruguay

A Cu(I)-sensing ArsR family metal sensor protein with a relaxed metal selectivity profile.

artículo científico publicado en 2008

Aggregation-Prone Amyloid-β⋅Cu(II) Species Formed on the Millisecond Timescale under Mildly Acidic Conditions.

artículo científico publicado en 2015

Amyloid-β and α-Synuclein Decrease the Level of Metal-Catalyzed Reactive Oxygen Species by Radical Scavenging and Redox Silencing

artículo científico publicado en 2016

Application of 204mPb perturbed angular correlation of γ-rays spectroscopy in coordination chemistry

artículo científico publicado en 2012

As<sup>III</sup> Selectively Induces a Disorder-to-Order Transition in the Metalloid Binding Region of the AfArsR Protein

artículo científico publicado en 2024

Billion-fold enhancement in sensitivity of nuclear magnetic resonance spectroscopy for magnesium ions in solution

artículo científico publicado en 2014

Binding of D- and L-captopril inhibitors to metallo-beta-lactamase studied by polarizable molecular mechanics and quantum mechanics

artículo científico publicado en 2002

C-terminal Cysteines of CueR Act as Auxiliary Metal Site Ligands upon HgII Binding-A Mechanism To Prevent Transcriptional Activation by Divalent Metal Ions?

artículo científico publicado en 2019

Catalytic role of the metal ion in the metallo-beta-lactamase GOB.

artículo científico publicado en 2009

Cd-substituted horse liver alcohol dehydrogenase: catalytic site metal coordination geometry and protein conformation

artículo científico publicado en 1995

Comparison of the binding of cadmium(II), mercury(II), and arsenic(III) to the de novo designed peptides TRI L12C and TRI L16C.

artículo científico publicado en 2002

Coordination geometries for monovalent and divalent metal ions in [His121]azurin--studies using perturbed angular correlations of gamma-rays from 111Ag and 111mCd

artículo científico publicado en 1997

Design of a peptidic turn with high affinity for Hg(II)

scientific article published on 17 October 2012

Design of thiolate rich metal binding sites within a peptidic framework.

artículo científico publicado en 2008

Direct Observation of Nanosecond Water Exchange Dynamics at a Protein Metal Site

artículo científico publicado en 2016

Direct determination of absolute configuration of methyl-substituted phenyloxiranes: combined experimental and theoretical approach

artículo científico publicado en 2006

Direct observation of Mg complexes in ionic liquid solutions by Mg β-NMR spectroscopy

article

Docking and scoring of metallo-beta-lactamases inhibitors

artículo científico publicado en 2004

Dynamics of mononuclear cadmium beta-lactamase revealed by the combination of NMR and PAC spectroscopy

artículo científico publicado en 2001

Effect of inhibitors on the coordination geometries of cadmium at the metal sites in angiotensin-I-converting enzyme

artículo científico publicado en 1995

Effects of Cu(II) on the aggregation of amyloid-β

scientific article published on 10 October 2019

Electric field gradients in Hg compounds: molecular orbital (MO) analysis and comparison of 4-component and 2-component (ZORA) methods.

artículo científico publicado en 2012

Evaluation of carbohydrate molecular mechanical force fields by quantum mechanical calculations

artículo científico publicado en 2004

Fast cadmium inhibition of photosynthesis in cyanobacteria in vivo and in vitro studies using perturbed angular correlation of gamma-rays

artículo científico publicado en 2006

Fully relativistic coupled cluster and DFT study of electric field gradients at Hg in 199Hg compounds.

artículo científico publicado en 2012

Hg2+ and Cd2+ binding of a bioinspired hexapeptide with two cysteine units constructed as a minimalistic metal ion sensing fluorescent probe

scientific article published on 21 May 2019

Incorporation of second coordination sphere D-amino acids alters Cd(II) geometries in designed thiolate-rich proteins

artículo científico publicado en 2017

Interaction and coordination geometries for Ag(I) in the two metal sites of hemocyanin

artículo científico publicado en 2000

Long lived intermediate metal site structure upon binding of cadmium to plastocyanin

scientific article published on 29 November 2006

Metal ion mediated transition from random coil to β-sheet and aggregation of Bri2-23, a natural inhibitor of Aβ aggregation

artículo científico publicado en 2015

Nanosecond Dynamics at Protein Metal Sites: An Application of Perturbed Angular Correlation (PAC) of γ-Rays Spectroscopy.

artículo científico publicado en 2017

New leads of metallo-beta-lactamase inhibitors from structure-based pharmacophore design

artículo científico publicado en 2005

Nuclear magnetic resonance shielding constants and chemical shifts in linear 199Hg compounds: a comparison of three relativistic computational methods

scientific article published on 01 July 2011

Plastocyanin binding to photosystem I as a function of the charge state of the metal ion: effect of metal site conformation

artículo científico publicado en 1999

Preference of Cd(II) and Zn(II) for the two metal sites in Bacillus cereus beta-lactamase II: A perturbed angular correlation of gamma-rays spectroscopic study

scientific article published on 01 December 1999

Probing the coordination environment of the human copper chaperone HAH1: characterization of Hg(II)-bridged homodimeric species in solution.

artículo científico publicado en 2013

Rapid Formation of a Preoligomeric Peptide-Metal-Peptide Complex Following Copper(II) Binding to Amyloid β Peptides

scholarly article by Jeppe T. Pedersen et al published 17 February 2011 in Angewandte Chemie International Edition

Rapid exchange of metal between Zn(7)-metallothionein-3 and amyloid-β peptide promotes amyloid-related structural changes

artículo científico publicado en 2012

Reparameterization of all-atom dipalmitoylphosphatidylcholine lipid parameters enables simulation of fluid bilayers at zero tension.

artículo científico publicado en 2007

Specificity of the Metalloregulator CueR for Monovalent Metal Ions: Possible Functional Role of a Coordinated Thiol?

artículo científico publicado en 2015

Structural adaptability of zinc binding sites: different structures in partially, fully, and heavy-metal loaded states.

artículo científico publicado en 2009

Structural and functional characterization of Mycobacterium tuberculosis CmtR, a PbII/CdII-sensing SmtB/ArsR metalloregulatory repressor

scientific journal article

Structure and absolute configuration of nyasol and hinokiresinol via synthesis and vibrational circular dichroism spectroscopy

artículo científico publicado en 2005

Structure and dynamics of the metal site of cadmium-substituted carboxypeptidase A in solution and crystalline states and under steady-state peptide hydrolysis

scientific article published on 01 September 1997

Structure of metal site in Cd-substituted His117Gly mutant of azurin with and without addition of imidazole derivatives

artículo científico publicado en 1995

Structure, Chemical Bonding, and Nuclear Quadrupole Interactions of beta-Cd(OH)(2): Experiment and First Principles Calculations

artículo científico publicado en 1999

The Pathogenic A2V Mutant Exhibits Distinct Aggregation Kinetics, Metal Site Structure, and Metal Exchange of the Cu2+ -Aβ Complex.

artículo científico publicado en 2017

The application of (199)Hg NMR and (199m)Hg perturbed angular correlation (PAC) spectroscopy to define the biological chemistry of Hg(II): a case study with designed two- and three-stranded coiled coils.

artículo científico publicado en 2007

The protein conformation of Cd-substituted horse liver alcohol dehydrogenase and its metal-site coordination geometry in binary and ternary inhibitor complexes

artículo científico publicado en 1996

Towards the role of metal ions in the structural variability of proteins: CdII speciation of a metal ion binding loop motif

scientific article published on 31 October 2011

Using diastereopeptides to control metal ion coordination in proteins

artículo científico publicado en 2008

Using nonnatural amino acids to control metal-coordination number in three-stranded coiled coils

scientific article published on 01 April 2006

Variable primary coordination environments of Cd(II) binding to three helix bundles provide a pathway for rapid metal exchange.

artículo científico publicado en 2015

Zinc ion-induced domain organization in metallo-beta-lactamases: a flexible "zinc arm" for rapid metal ion transfer?

artículo científico publicado en 2009

Zn(II) and Hg(II) binding to a designed peptide that accommodates different coordination geometries

artículo científico publicado en 2015

d-Cysteine Ligands Control Metal Geometries within De Novo Designed Three-Stranded Coiled Coils

artículo científico publicado en 2017

pH-dependent structural change of reduced spinach plastocyanin studied by perturbed angular correlation of γ-rays and dynamic light scattering

scientific article published on 30 March 2006

Lista de obras de Lars Hemmingsen

A Cu(I)-sensing ArsR family metal sensor protein with a relaxed metal selectivity profile.

Aggregation-Prone Amyloid-β⋅Cu(II) Species Formed on the Millisecond Timescale under Mildly Acidic Conditions.

Amyloid-β and α-Synuclein Decrease the Level of Metal-Catalyzed Reactive Oxygen Species by Radical Scavenging and Redox Silencing

Application of 204mPb perturbed angular correlation of γ-rays spectroscopy in coordination chemistry

As<sup>III</sup> Selectively Induces a Disorder-to-Order Transition in the Metalloid Binding Region of the AfArsR Protein

Billion-fold enhancement in sensitivity of nuclear magnetic resonance spectroscopy for magnesium ions in solution

Binding of D- and L-captopril inhibitors to metallo-beta-lactamase studied by polarizable molecular mechanics and quantum mechanics

C-terminal Cysteines of CueR Act as Auxiliary Metal Site Ligands upon HgII Binding-A Mechanism To Prevent Transcriptional Activation by Divalent Metal Ions?

Catalytic role of the metal ion in the metallo-beta-lactamase GOB.

Cd-substituted horse liver alcohol dehydrogenase: catalytic site metal coordination geometry and protein conformation

Comparison of the binding of cadmium(II), mercury(II), and arsenic(III) to the de novo designed peptides TRI L12C and TRI L16C.

Coordination geometries for monovalent and divalent metal ions in [His121]azurin--studies using perturbed angular correlations of gamma-rays from 111Ag and 111mCd

Design of a peptidic turn with high affinity for Hg(II)

Design of thiolate rich metal binding sites within a peptidic framework.

Direct Observation of Nanosecond Water Exchange Dynamics at a Protein Metal Site

Direct determination of absolute configuration of methyl-substituted phenyloxiranes: combined experimental and theoretical approach

Direct observation of Mg complexes in ionic liquid solutions by Mg β-NMR spectroscopy

Docking and scoring of metallo-beta-lactamases inhibitors

Dynamics of mononuclear cadmium beta-lactamase revealed by the combination of NMR and PAC spectroscopy

Effect of inhibitors on the coordination geometries of cadmium at the metal sites in angiotensin-I-converting enzyme

Effects of Cu(II) on the aggregation of amyloid-β

Electric field gradients in Hg compounds: molecular orbital (MO) analysis and comparison of 4-component and 2-component (ZORA) methods.

Evaluation of carbohydrate molecular mechanical force fields by quantum mechanical calculations

Fast cadmium inhibition of photosynthesis in cyanobacteria in vivo and in vitro studies using perturbed angular correlation of gamma-rays

Fully relativistic coupled cluster and DFT study of electric field gradients at Hg in 199Hg compounds.

Hg2+ and Cd2+ binding of a bioinspired hexapeptide with two cysteine units constructed as a minimalistic metal ion sensing fluorescent probe

Incorporation of second coordination sphere D-amino acids alters Cd(II) geometries in designed thiolate-rich proteins

Interaction and coordination geometries for Ag(I) in the two metal sites of hemocyanin

Long lived intermediate metal site structure upon binding of cadmium to plastocyanin

Metal ion mediated transition from random coil to β-sheet and aggregation of Bri2-23, a natural inhibitor of Aβ aggregation

Nanosecond Dynamics at Protein Metal Sites: An Application of Perturbed Angular Correlation (PAC) of γ-Rays Spectroscopy.

New leads of metallo-beta-lactamase inhibitors from structure-based pharmacophore design

Nuclear magnetic resonance shielding constants and chemical shifts in linear 199Hg compounds: a comparison of three relativistic computational methods

Plastocyanin binding to photosystem I as a function of the charge state of the metal ion: effect of metal site conformation

Preference of Cd(II) and Zn(II) for the two metal sites in Bacillus cereus beta-lactamase II: A perturbed angular correlation of gamma-rays spectroscopic study

Probing the coordination environment of the human copper chaperone HAH1: characterization of Hg(II)-bridged homodimeric species in solution.

Rapid Formation of a Preoligomeric Peptide-Metal-Peptide Complex Following Copper(II) Binding to Amyloid β Peptides

Rapid exchange of metal between Zn(7)-metallothionein-3 and amyloid-β peptide promotes amyloid-related structural changes

Reparameterization of all-atom dipalmitoylphosphatidylcholine lipid parameters enables simulation of fluid bilayers at zero tension.

Specificity of the Metalloregulator CueR for Monovalent Metal Ions: Possible Functional Role of a Coordinated Thiol?

Structural adaptability of zinc binding sites: different structures in partially, fully, and heavy-metal loaded states.

Structural and functional characterization of Mycobacterium tuberculosis CmtR, a PbII/CdII-sensing SmtB/ArsR metalloregulatory repressor

Structure and absolute configuration of nyasol and hinokiresinol via synthesis and vibrational circular dichroism spectroscopy

Structure and dynamics of the metal site of cadmium-substituted carboxypeptidase A in solution and crystalline states and under steady-state peptide hydrolysis

Structure of metal site in Cd-substituted His117Gly mutant of azurin with and without addition of imidazole derivatives

Structure, Chemical Bonding, and Nuclear Quadrupole Interactions of beta-Cd(OH)(2): Experiment and First Principles Calculations

The Pathogenic A2V Mutant Exhibits Distinct Aggregation Kinetics, Metal Site Structure, and Metal Exchange of the Cu2+ -Aβ Complex.

The application of (199)Hg NMR and (199m)Hg perturbed angular correlation (PAC) spectroscopy to define the biological chemistry of Hg(II): a case study with designed two- and three-stranded coiled coils.

The protein conformation of Cd-substituted horse liver alcohol dehydrogenase and its metal-site coordination geometry in binary and ternary inhibitor complexes

Towards the role of metal ions in the structural variability of proteins: CdII speciation of a metal ion binding loop motif

Using diastereopeptides to control metal ion coordination in proteins

Using nonnatural amino acids to control metal-coordination number in three-stranded coiled coils

Variable primary coordination environments of Cd(II) binding to three helix bundles provide a pathway for rapid metal exchange.

Zinc ion-induced domain organization in metallo-beta-lactamases: a flexible "zinc arm" for rapid metal ion transfer?

Zn(II) and Hg(II) binding to a designed peptide that accommodates different coordination geometries

d-Cysteine Ligands Control Metal Geometries within De Novo Designed Three-Stranded Coiled Coils

pH-dependent structural change of reduced spinach plastocyanin studied by perturbed angular correlation of γ-rays and dynamic light scattering