Lista de obras - José A. Melero - Dominio Público Uruguay

A primer vector system that allows temperature dependent gene amplification and expression in mammalian cells: regulation of the influenza virus NS1 gene expression

artículo científico publicado en 1985

Analysis of genetic variability in human respiratory syncytial virus by the RNase A mismatch cleavage method: subtype divergence and heterogeneity

artículo científico publicado en 1990

Antibody-Induced Internalization of the Human Respiratory Syncytial Virus Fusion Protein

artículo científico publicado en 2017

Antigenic structure of the human respiratory syncytial virus G glycoprotein and relevance of hypermutation events for the generation of antigenic variants

artículo científico publicado en 1997

Apoptosis, Toll-like, RIG-I-like and NOD-like Receptors Are Pathways Jointly Induced by Diverse Respiratory Bacterial and Viral Pathogens

artículo científico publicado en 2017

Binding of human respiratory syncytial virus to cells: implication of sulfated cell surface proteoglycans.

artículo científico publicado en 2000

Characterization in vitro and in vivo of a pandemic H1N1 influenza virus from a fatal case.

artículo científico publicado en 2013

Characterization of a Prefusion-Specific Antibody That Recognizes a Quaternary, Cleavage-Dependent Epitope on the RSV Fusion Glycoprotein

artículo científico publicado en 2015

Characterization of a human astrovirus serotype 2 structural protein (VP26) that contains an epitope involved in virus neutralization.

artículo científico publicado en 1994

Chimeric Pneumoviridae fusion proteins as immunogens to induce cross-neutralizing antibody responses

artículo científico publicado en 2017

Cleavage of the human respiratory syncytial virus fusion protein at two distinct sites is required for activation of membrane fusion

artículo científico publicado en 2001

Clinical response to pandemic H1N1 influenza virus from a fatal and mild case in ferrets.

artículo científico publicado en 2015

Conformational constraints of conserved neutralizing epitopes from a major antigenic area of human respiratory syncytial virus fusion glycoprotein.

artículo científico publicado en 1993

Conservation of G-Protein Epitopes in Respiratory Syncytial Virus (Group A) Despite Broad Genetic Diversity: Is Antibody Selection Involved in Virus Evolution?

artículo científico publicado en 2015

Construction of cell lines that regulate by temperature the amplification and expression of influenza virus non-structural protein genes

artículo científico publicado en 1986

Coordinate expression of the 48K host nuclear phosphoprotein and SV40 T Ag upon primary infection of mouse cells ⬇️

artículo científico publicado el 30 de abril de 1980

Corrigendum: Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state

artículo científico publicado en 2017

Cytoplasmic inclusions of respiratory syncytial virus-infected cells: formation of inclusion bodies in transfected cells that coexpress the nucleoprotein, the phosphoprotein, and the 22K protein

artículo científico publicado en 1993

Deoxyribinucleic acid-binding proteins in virus-transformed cell lines ⬇️

artículo científico publicado el 25 de mayo de 1975

Effect of proteolytic processing at two distinct sites on shape and aggregation of an anchorless fusion protein of human respiratory syncytial virus and fate of the intervening segment.

artículo científico publicado en 2002

Electron microscopy of the human respiratory syncytial virus fusion protein and complexes that it forms with monoclonal antibodies

artículo científico publicado en 2000

Eliminating a region of respiratory syncytial virus attachment protein allows induction of protective immunity without vaccine-enhanced lung eosinophilia.

artículo científico publicado en 1998

Engineering, Structure and Immunogenicity of the Human Metapneumovirus F Protein in the Postfusion Conformation.

artículo científico publicado en 2016

Enhanced neutralization of human respiratory syncytial virus by mixtures of monoclonal antibodies to the attachment (G) glycoprotein

artículo científico publicado en 1998

Entry of enveloped viruses into host cells: membrane fusion

artículo científico publicado en 2013

Evaluation of the antibody specificities of human convalescent-phase sera against the attachment (G) protein of human respiratory syncytial virus: influence of strain variation and carbohydrate side chains

artículo científico publicado en 2000

Evolution of the G and P genes of human respiratory syncytial virus (subgroup A) studied by the RNase A mismatch cleavage method

artículo científico publicado en 1991

Exogenous, TAP-independent lysosomal presentation of a respiratory syncytial virus CTL epitope

artículo científico publicado en 2012

Frame shift mutations as a novel mechanism for the generation of neutralization resistant mutants of human respiratory syncytial virus.

artículo científico publicado en 1990

Generation and Characterization of ALX-0171, a Potent Novel Therapeutic Nanobody for the Treatment of Respiratory Syncytial Virus Infection

artículo científico publicado en 2015

Generation of monoclonal antibodies specific of the postfusion conformation of the Pneumovirinae fusion (F) protein.

artículo científico publicado en 2015

High level expression of soluble glycoproteins in the allantoic fluid of embryonated chicken eggs using a Sendai virus minigenome system

artículo científico publicado en 2007

Host nuclear proteins expressed in simian virus 40-transformed and -infected cells

artículo científico publicado en 1980

Human respiratory syncytial virus infects and induces activation markers in mouse B lymphocytes

artículo científico publicado en 2009

ISG15 Is Upregulated in Respiratory Syncytial Virus Infection and Reduces Virus Growth through Protein ISGylation.

artículo científico publicado en 2016

Identification of the glucose/glycosylation‐regulated proteins as those which accumulate in the temperature‐sensitive cell line K12 ⬇️

artículo científico publicado el 1 de octubre de 1981

Influence of Respiratory Syncytial Virus F Glycoprotein Conformation on Induction of Protective Immune Responses.

scientific article published on 23 March 2016

Influence of antigen conformation and mode of presentation on the antibody and protective responses against human respiratory syncytial virus: relevance for vaccine development

artículo científico publicado en 2016

Intensified-Fenton process for the treatment of phenol aqueous solutions

artículo científico publicado en 2015

Isolation and cell cycle analysis of temperature-sensitive mutants from Chinese hamster cells

artículo científico publicado el 1 de enero de 1979

Llama-derived single domain antibodies to build multivalent, superpotent and broadened neutralizing anti-viral molecules

artículo científico publicado en 2011

Location of the epitope recognized by monoclonal antibody 63G on the primary structure of human respiratory syncytial virus G glycoprotein and the ability of synthetic peptides containing this epitope to induce neutralizing antibodies

artículo científico publicado en 1992

Low-pH-induced membrane fusion mediated by human metapneumovirus F protein is a rare, strain-dependent phenomenon

artículo científico publicado en 2008

Major changes in the G protein of human respiratory syncytial virus isolates introduced by a duplication of 60 nucleotides.

artículo científico publicado en 2003

Membrane permeability changes induced in Escherichia coli by the SH protein of human respiratory syncytial virus.

artículo científico publicado en 1997

Mutant forms of the F protein of human respiratory syncytial (RS) virus induce a cytotoxic T lymphocyte response but not a neutralizing antibody response and only transient resistance to RS virus infection

artículo científico publicado en 1996

Nuclear transport of influenza virus polymerase PA protein.

artículo científico publicado en 1992

Nucleotide sequence of the fusion and phosphoprotein genes of human respiratory syncytial (RS) virus Long strain: evidence of subtype genetic heterogeneity

artículo científico publicado en 1988

Participation of cytoskeletal intermediate filaments in the infectious cycle of human respiratory syncytial virus (RSV).

artículo científico publicado en 1988

Polyclonal and monoclonal antibodies specific for the six-helix bundle of the human respiratory syncytial virus fusion glycoprotein as probes of the protein post-fusion conformation.

artículo científico publicado en 2014

Polylactide-co-glycolide (PLG) microparticles modify the immune response to DNA vaccination

article

Possible transcriptional control of three polypeptides which accumulate in a temperature-sensitive mammalian cell line

artículo científico publicado en 1978

Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state.

artículo científico publicado en 2017

Progress in understanding and controlling respiratory syncytial virus: still crazy after all these years

artículo científico publicado en 2011

Rapid profiling of RSV antibody repertoires from the memory B cells of naturally infected adult donors

artículo científico publicado en 2016

Recombinant Soluble Respiratory Syncytial Virus F Protein That Lacks Heptad Repeat B, Contains a GCN4 Trimerization Motif and Is Not Cleaved Displays Prefusion-Like Characteristics.

artículo científico publicado en 2015

Reduced innate immune response, apoptosis, and virus release in cells cured of respiratory syncytial virus persistent infection.

artículo científico publicado en 2010

Relevance of viral context and diversity of antigen-processing routes for respiratory syncytial virus cytotoxic T-lymphocyte epitopes

artículo científico publicado en 2008

Respiratory syncytial virus and other pneumoviruses: a review of the international symposium--RSV 2003.

artículo científico publicado en 2004

Respiratory syncytial virus infection of gene gun vaccinated mice induces Th2-driven pulmonary eosinophilia even in the absence of sensitisation to the fusion (F) or attachment (G) protein

artículo científico publicado en 2000

Roflumilast inhibits respiratory syncytial virus infection in human differentiated bronchial epithelial cells

artículo científico publicado en 2013

Selection and characterization of human respiratory syncytial virus escape mutants resistant to a polyclonal antiserum raised against the F protein

artículo científico publicado en 2012

Social, economic, and health impact of the respiratory syncytial virus: a systematic search

artículo científico publicado en 2014

Structural, antigenic and immunogenic features of respiratory syncytial virus glycoproteins relevant for vaccine development

artículo científico publicado en 2016

Structure and immunogenicity of pre-fusion-stabilized human metapneumovirus F glycoprotein.

artículo científico publicado en 2017

Subcellular distribution of DNA-binding proteins from cultured hamster fibroblasts

artículo científico publicado en 1976

Ten years of global evolution of the human respiratory syncytial virus BA genotype with a 60-nucleotide duplication in the G protein gene

artículo científico publicado en 2010

The Complexity of Antibody Responses Elicited against the Respiratory Syncytial Virus Glycoproteins in Hospitalized Children Younger than 2 Years

artículo científico publicado en 2017

The Effect of Heat-inactivated Murine Cytomegalovirus on Host DNA Synthesis of Different Cells

artículo científico publicado el 1 de junio de 1978

The G protein of human respiratory syncytial virus: significance of carbohydrate side-chains and the C-terminal end to its antigenicity

artículo científico publicado en 1991

The Pneumovirinae fusion (F) protein: A common target for vaccines and antivirals

artículo científico publicado en 2015

The cysteine-rich region of respiratory syncytial virus attachment protein inhibits innate immunity elicited by the virus and endotoxin

artículo científico publicado en 2005

The main allergen of Olea europaea (Ole e I) is also present in other species of the Oleaceae family

artículo científico publicado en 1993

The respiratory syncytial virus vaccine landscape: lessons from the graveyard and promising candidates

scholarly article by Natalie I Mazur et al published October 2018 in Lancet Infectious Diseases

The three C-terminal residues of human respiratory syncytial virus G glycoprotein (Long strain) are essential for integrity of multiple epitopes distinguishable by antiidiotypic antibodies

artículo científico publicado en 1995

The use of monoclonal antibodies and lectins to identify changes in viral glycoproteins that are influenced by glycosylation: the case of human respiratory syncytial virus attachment (G) glycoprotein.

artículo científico publicado en 2007

Thermostability of the human respiratory syncytial virus fusion protein before and after activation: implications for the membrane-fusion mechanism

artículo científico publicado en 2004

Trivalency of a Nanobody Specific for the Human Respiratory Syncytial Virus Fusion Glycoprotein Drastically Enhances Virus Neutralization and Impacts Escape Mutant Selection

artículo científico publicado en 2016

Unusual antigenic and genetic characteristics of human respiratory syncytial viruses isolated in Cuba.

artículo científico publicado en 1998

Venous Collector in a Case of Partial Anomalous Pulmonary Venous Drainage

artículo científico publicado en 2015

Xylose isomerization with zeolites in a two-step alcohol-water process.

artículo científico publicado en 2015

Lista de obras de José A. Melero

A primer vector system that allows temperature dependent gene amplification and expression in mammalian cells: regulation of the influenza virus NS1 gene expression

Analysis of genetic variability in human respiratory syncytial virus by the RNase A mismatch cleavage method: subtype divergence and heterogeneity

Antibody-Induced Internalization of the Human Respiratory Syncytial Virus Fusion Protein

Antigenic structure of the human respiratory syncytial virus G glycoprotein and relevance of hypermutation events for the generation of antigenic variants

Apoptosis, Toll-like, RIG-I-like and NOD-like Receptors Are Pathways Jointly Induced by Diverse Respiratory Bacterial and Viral Pathogens

Binding of human respiratory syncytial virus to cells: implication of sulfated cell surface proteoglycans.

Characterization in vitro and in vivo of a pandemic H1N1 influenza virus from a fatal case.

Characterization of a Prefusion-Specific Antibody That Recognizes a Quaternary, Cleavage-Dependent Epitope on the RSV Fusion Glycoprotein

Characterization of a human astrovirus serotype 2 structural protein (VP26) that contains an epitope involved in virus neutralization.

Chimeric Pneumoviridae fusion proteins as immunogens to induce cross-neutralizing antibody responses

Cleavage of the human respiratory syncytial virus fusion protein at two distinct sites is required for activation of membrane fusion

Clinical response to pandemic H1N1 influenza virus from a fatal and mild case in ferrets.

Conformational constraints of conserved neutralizing epitopes from a major antigenic area of human respiratory syncytial virus fusion glycoprotein.

Conservation of G-Protein Epitopes in Respiratory Syncytial Virus (Group A) Despite Broad Genetic Diversity: Is Antibody Selection Involved in Virus Evolution?

Construction of cell lines that regulate by temperature the amplification and expression of influenza virus non-structural protein genes

Coordinate expression of the 48K host nuclear phosphoprotein and SV40 T Ag upon primary infection of mouse cells ⬇️

Corrigendum: Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state

Cytoplasmic inclusions of respiratory syncytial virus-infected cells: formation of inclusion bodies in transfected cells that coexpress the nucleoprotein, the phosphoprotein, and the 22K protein

Deoxyribinucleic acid-binding proteins in virus-transformed cell lines ⬇️

Effect of proteolytic processing at two distinct sites on shape and aggregation of an anchorless fusion protein of human respiratory syncytial virus and fate of the intervening segment.

Electron microscopy of the human respiratory syncytial virus fusion protein and complexes that it forms with monoclonal antibodies

Eliminating a region of respiratory syncytial virus attachment protein allows induction of protective immunity without vaccine-enhanced lung eosinophilia.

Engineering, Structure and Immunogenicity of the Human Metapneumovirus F Protein in the Postfusion Conformation.

Enhanced neutralization of human respiratory syncytial virus by mixtures of monoclonal antibodies to the attachment (G) glycoprotein

Entry of enveloped viruses into host cells: membrane fusion

Evaluation of the antibody specificities of human convalescent-phase sera against the attachment (G) protein of human respiratory syncytial virus: influence of strain variation and carbohydrate side chains

Evolution of the G and P genes of human respiratory syncytial virus (subgroup A) studied by the RNase A mismatch cleavage method

Exogenous, TAP-independent lysosomal presentation of a respiratory syncytial virus CTL epitope

Frame shift mutations as a novel mechanism for the generation of neutralization resistant mutants of human respiratory syncytial virus.

Generation and Characterization of ALX-0171, a Potent Novel Therapeutic Nanobody for the Treatment of Respiratory Syncytial Virus Infection

Generation of monoclonal antibodies specific of the postfusion conformation of the Pneumovirinae fusion (F) protein.

High level expression of soluble glycoproteins in the allantoic fluid of embryonated chicken eggs using a Sendai virus minigenome system

Host nuclear proteins expressed in simian virus 40-transformed and -infected cells

Human respiratory syncytial virus infects and induces activation markers in mouse B lymphocytes

ISG15 Is Upregulated in Respiratory Syncytial Virus Infection and Reduces Virus Growth through Protein ISGylation.

Identification of the glucose/glycosylation‐regulated proteins as those which accumulate in the temperature‐sensitive cell line K12 ⬇️

Influence of Respiratory Syncytial Virus F Glycoprotein Conformation on Induction of Protective Immune Responses.

Influence of antigen conformation and mode of presentation on the antibody and protective responses against human respiratory syncytial virus: relevance for vaccine development

Intensified-Fenton process for the treatment of phenol aqueous solutions

Isolation and cell cycle analysis of temperature-sensitive mutants from Chinese hamster cells

Llama-derived single domain antibodies to build multivalent, superpotent and broadened neutralizing anti-viral molecules

Location of the epitope recognized by monoclonal antibody 63G on the primary structure of human respiratory syncytial virus G glycoprotein and the ability of synthetic peptides containing this epitope to induce neutralizing antibodies

Low-pH-induced membrane fusion mediated by human metapneumovirus F protein is a rare, strain-dependent phenomenon

Major changes in the G protein of human respiratory syncytial virus isolates introduced by a duplication of 60 nucleotides.

Membrane permeability changes induced in Escherichia coli by the SH protein of human respiratory syncytial virus.

Mutant forms of the F protein of human respiratory syncytial (RS) virus induce a cytotoxic T lymphocyte response but not a neutralizing antibody response and only transient resistance to RS virus infection

Nuclear transport of influenza virus polymerase PA protein.

Nucleotide sequence of the fusion and phosphoprotein genes of human respiratory syncytial (RS) virus Long strain: evidence of subtype genetic heterogeneity

Participation of cytoskeletal intermediate filaments in the infectious cycle of human respiratory syncytial virus (RSV).

Polyclonal and monoclonal antibodies specific for the six-helix bundle of the human respiratory syncytial virus fusion glycoprotein as probes of the protein post-fusion conformation.

Polylactide-co-glycolide (PLG) microparticles modify the immune response to DNA vaccination

Possible transcriptional control of three polypeptides which accumulate in a temperature-sensitive mammalian cell line

Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state.

Progress in understanding and controlling respiratory syncytial virus: still crazy after all these years

Rapid profiling of RSV antibody repertoires from the memory B cells of naturally infected adult donors

Recombinant Soluble Respiratory Syncytial Virus F Protein That Lacks Heptad Repeat B, Contains a GCN4 Trimerization Motif and Is Not Cleaved Displays Prefusion-Like Characteristics.

Reduced innate immune response, apoptosis, and virus release in cells cured of respiratory syncytial virus persistent infection.

Relevance of viral context and diversity of antigen-processing routes for respiratory syncytial virus cytotoxic T-lymphocyte epitopes

Respiratory syncytial virus and other pneumoviruses: a review of the international symposium--RSV 2003.

Respiratory syncytial virus infection of gene gun vaccinated mice induces Th2-driven pulmonary eosinophilia even in the absence of sensitisation to the fusion (F) or attachment (G) protein

Roflumilast inhibits respiratory syncytial virus infection in human differentiated bronchial epithelial cells

Selection and characterization of human respiratory syncytial virus escape mutants resistant to a polyclonal antiserum raised against the F protein

Social, economic, and health impact of the respiratory syncytial virus: a systematic search

Structural, antigenic and immunogenic features of respiratory syncytial virus glycoproteins relevant for vaccine development

Structure and immunogenicity of pre-fusion-stabilized human metapneumovirus F glycoprotein.

Subcellular distribution of DNA-binding proteins from cultured hamster fibroblasts

Ten years of global evolution of the human respiratory syncytial virus BA genotype with a 60-nucleotide duplication in the G protein gene

The Complexity of Antibody Responses Elicited against the Respiratory Syncytial Virus Glycoproteins in Hospitalized Children Younger than 2 Years

The Effect of Heat-inactivated Murine Cytomegalovirus on Host DNA Synthesis of Different Cells

The G protein of human respiratory syncytial virus: significance of carbohydrate side-chains and the C-terminal end to its antigenicity

The Pneumovirinae fusion (F) protein: A common target for vaccines and antivirals

The cysteine-rich region of respiratory syncytial virus attachment protein inhibits innate immunity elicited by the virus and endotoxin

The main allergen of Olea europaea (Ole e I) is also present in other species of the Oleaceae family

The respiratory syncytial virus vaccine landscape: lessons from the graveyard and promising candidates

The three C-terminal residues of human respiratory syncytial virus G glycoprotein (Long strain) are essential for integrity of multiple epitopes distinguishable by antiidiotypic antibodies

The use of monoclonal antibodies and lectins to identify changes in viral glycoproteins that are influenced by glycosylation: the case of human respiratory syncytial virus attachment (G) glycoprotein.

Thermostability of the human respiratory syncytial virus fusion protein before and after activation: implications for the membrane-fusion mechanism

Trivalency of a Nanobody Specific for the Human Respiratory Syncytial Virus Fusion Glycoprotein Drastically Enhances Virus Neutralization and Impacts Escape Mutant Selection

Unusual antigenic and genetic characteristics of human respiratory syncytial viruses isolated in Cuba.