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Lista de obras de Dolors Serra Cucurull

(-)-UB006: A new fatty acid synthase inhibitor and cytotoxic agent without anorexic side effects.

artículo científico publicado en 2017

Altered circadian rhythm and metabolic gene profile in rats subjected to advanced light phase shifts

artículo científico publicado en 2015

An overview of nanomedicines for neuron targeting

artículo científico publicado en 2020

Brown Adipose Tissue Bioenergetics: A New Methodological Approach

artículo científico publicado en 2017

C75 is converted to C75-CoA in the hypothalamus, where it inhibits carnitine palmitoyltransferase 1 and decreases food intake and body weight

artículo científico publicado en 2008

CPT I overexpression protects L6E9 muscle cells from fatty acid-induced insulin resistance

artículo científico publicado en 2006

CPT1C in the ventromedial nucleus of the hypothalamus is necessary for brown fat thermogenesis activation in obesity.

artículo científico publicado en 2018

CPT1c is localized in endoplasmic reticulum of neurons and has carnitine palmitoyltransferase activity

scientific journal article

Carnitine Palmitoyltransferase 1 Increases Lipolysis, UCP1 Protein Expression and Mitochondrial Activity in Brown Adipocytes

artículo científico publicado en 2016

Carnitine palmitoyltransferase 1C: From cognition to cancer.

artículo científico

Central ceramide-induced hypothalamic lipotoxicity and ER stress regulate energy balance

artículo científico publicado en 2014

Ceramide levels regulated by carnitine palmitoyltransferase 1C control dendritic spine maturation and cognition

artículo científico publicado en 2012

Ceramides and mitochondrial fatty acid oxidation in obesity.

artículo científico publicado en 2016

Definition by functional and structural analysis of two malonyl-CoA sites in carnitine palmitoyltransferase 1A

artículo científico publicado en 2007

Developmental changes in carnitine octanoyltransferase gene expression in intestine and liver of suckling rats

artículo científico publicado en 2001

Developmental changes in the phospho(enol)pyruvate carboxykinase gene expression in small intestine and liver of suckling rats.

artículo científico publicado en 1996

Enhanced fatty acid oxidation in adipocytes and macrophages reduces lipid-induced triglyceride accumulation and inflammation.

artículo científico publicado en 2015

Enhancing hepatic fatty acid oxidation as a strategy for reversing metabolic disorders programmed by maternal undernutrition during gestation

artículo científico publicado en 2014

Essential role of Nrf2 in the protective effect of lipoic acid against lipoapoptosis in hepatocytes

artículo científico publicado en 2015

Fatty acid metabolism and the basis of brown adipose tissue function

artículo científico publicado en 2015

Fatty acid synthase is a metabolic marker of cell proliferation rather than malignancy in ovarian cancer and its precursor cells.

artículo científico publicado en 2014

Ghrelin Causes a Decline in GABA Release by Reducing Fatty Acid Oxidation in Cortex.

artículo científico publicado en 2018

HIF drives lipid deposition and cancer in ccRCC via repression of fatty acid metabolism

artículo científico publicado en 2017

Hypothalamic ceramide levels regulated by CPT1C mediate the orexigenic effect of ghrelin.

artículo científico publicado en 2013

Hypothalamic regulation of liver and muscle nutrient partitioning by brain-specific carnitine palmitoyltransferase 1C (CPT1C) in male mice.

artículo científico publicado en 2017

Identification of the two histidine residues responsible for the inhibition by malonyl-CoA in peroxisomal carnitine octanoyltransferase from rat liver

artículo científico publicado en 2000

Impaired ketogenesis is a major mechanism for disturbed hepatic fatty acid metabolism in rats with long-term cholestasis and after relief of biliary obstruction

scientific journal article

Important role of ventromedial hypothalamic carnitine palmitoyltransferase-1a in the control of food intake.

artículo científico publicado en 2013

Increased inflammation, oxidative stress and mitochondrial respiration in brown adipose tissue from obese mice

artículo científico publicado en 2017

Influence of etomoxir on the expression of several genes in liver, testis and heart.

artículo científico publicado en 1995

Inhibition by etomoxir of rat liver carnitine octanoyltransferase is produced through the co-ordinate interaction with two histidine residues

scientific journal article

Ketogenic mitochondrial 3-hydroxy 3-methylglutaryl-CoA synthase gene expression in intestine and liver of suckling rats

artículo científico publicado en 1993

Localization of an exonic splicing enhancer responsible for mammalian natural trans-splicing.

artículo científico publicado en 2001

Long-term increased carnitine palmitoyltransferase 1A expression in ventromedial hypotalamus causes hyperphagia and alters the hypothalamic lipidomic profile

artículo científico publicado en 2014

Malonyl-CoA mediates leptin hypothalamic control of feeding independent of inhibition of CPT-1a

artículo científico publicado en 2011

Mitochondrial 3-hydroxy-3-methylglutaryl coenzyme A synthase and carnitine palmitoyltransferase II as potential control sites for ketogenesis during mitochondrion and peroxisome proliferation

scientific journal article

Mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase promoter contains a CREB binding site that regulates cAMP action in Caco-2 cells

artículo científico publicado en 2000

Mitochondrial fatty acid oxidation in obesity

artículo científico publicado en 2013

Modulation in vitro of H-ras oncogene expression by trans-splicing

artículo científico publicado en 2001

Molecular therapy for obesity and diabetes based on a long-term increase in hepatic fatty-acid oxidation

artículo científico publicado en 2011

Mutagenesis of Specific Amino Acids Converts Carnitine Acetyltransferase into Carnitine Palmitoyltransferase†

artículo científico publicado en 2006

Natural trans-splicing in carnitine octanoyltransferase pre-mRNAs in rat liver

artículo científico publicado en 1998

Novel effect of C75 on carnitine palmitoyltransferase I activity and palmitate oxidation

artículo científico publicado en 2006

Novel role of FATP1 in mitochondrial fatty acid oxidation in skeletal muscle cells

scientific journal article

Rapamycin negatively impacts insulin signaling, glucose uptake and uncoupling protein-1 in brown adipocytes

artículo científico publicado en 2016

Redesign of carnitine acetyltransferase specificity by protein engineering

scientific journal article

Regulation of mitochondrial 3-hydroxy-3-methylglutaryl-coenzyme A synthase protein by starvation, fat feeding, and diabetes

scientific journal article

Renal tubule Cpt1a overexpression protects from kidney fibrosis by restoring mitochondrial homeostasis

artículo científico publicado en 2021

Sensing of nutrients by CPT1C regulates late endosome/lysosome anterograde transport and axon growth

artículo científico publicado en 2019

Short-term vitamin E treatment impairs reactive oxygen species signaling required for adipose tissue expansion, resulting in fatty liver and insulin resistance in obese mice

artículo científico publicado en 2017

Structural (betaalpha)8 TIM barrel model of 3-hydroxy-3-methylglutaryl-coenzyme A lyase

artículo científico publicado en 2003

Structural model of a malonyl-CoA-binding site of carnitine octanoyltransferase and carnitine palmitoyltransferase I: mutational analysis of a malonyl-CoA affinity domain

scientific journal article

Structural model of carnitine palmitoyltransferase I based on the carnitine acetyltransferase crystal

artículo científico publicado en 2004

Structural model of the catalytic core of carnitine palmitoyltransferase I and carnitine octanoyltransferase (COT): mutation of CPT I histidine 473 and alanine 381 and COT alanine 238 impairs the catalytic activity

artículo científico publicado en 2001

Ten novel HMGCL mutations in 24 patients of different origin with 3-hydroxy-3-methyl-glutaric aciduria

artículo científico publicado en 2009

The effect of etomoxir on the mRNA levels of enzymes involved in ketogenesis and cholesterogenesis in rat liver

artículo científico publicado en 1994

The effect of fasting/refeeding and insulin treatment on the expression of the regulatory genes of ketogenesis in intestine and liver of suckling rats

scientific journal article