Lista de obras - Philippe G. Frank - Dominio Público Uruguay

A Western-type diet accelerates tumor progression in an autochthonous mouse model of prostate cancer

artículo científico publicado en 2010

A biphasic response of hepatobiliary cholesterol metabolism to dietary fat at the onset of obesity in the mouse

artículo científico publicado en 2005

ATR/TEM8 is highly expressed in epithelial cells lining Bacillus anthracis' three sites of entry: implications for the pathogenesis of anthrax infection

artículo científico publicado en 2005

Ablation of calcineurin Aβ reveals hyperlipidemia and signaling cross-talks with phosphodiesterases

artículo científico publicado en 2012

Adenovirus-mediated expression of caveolin-1 in mouse liver increases plasma high-density lipoprotein levels

artículo científico publicado en 2001

Alterations in membrane caveolae and BKCa channel activity in skin fibroblasts in Smith-Lemli-Opitz syndrome

artículo científico publicado en 2011

Altered emotionality, spatial memory and cholinergic function in caveolin-1 knock-out mice

artículo científico publicado en 2007

Apolipoprotein A-I conformation in reconstituted discoidal lipoproteins varying in phospholipid and cholesterol content

artículo científico publicado en 1995

Caveolin, caveolae, and endothelial cell function

artículo científico publicado en 2003

Caveolin-1 (P132L), a common breast cancer mutation, confers mammary cell invasiveness and defines a novel stem cell/metastasis-associated gene signature

artículo científico publicado en 2009

Caveolin-1 Null (−/−) Mice Show Dramatic Reductions in Life Span†

scientific article published on 01 December 2003

Caveolin-1 and caveolae in atherosclerosis: differential roles in fatty streak formation and neointimal hyperplasia

artículo científico publicado en 2004

Caveolin-1 and regulation of cellular cholesterol homeostasis

scientific journal article

Caveolin-1 deficiency stimulates neointima formation during vascular injury

artículo científico publicado en 2004

Caveolin-1 expression negatively regulates cell cycle progression by inducing G(0)/G(1) arrest via a p53/p21(WAF1/Cip1)-dependent mechanism.

artículo científico publicado en 2001

Caveolin-1 promotes tumor progression in an autochthonous mouse model of prostate cancer: genetic ablation of Cav-1 delays advanced prostate tumor development in tramp mice

artículo científico publicado en 2005

Caveolin-1 regulates the anti-atherogenic properties of macrophages

artículo científico publicado en 2014

Caveolin-1-/- null mammary stromal fibroblasts share characteristics with human breast cancer-associated fibroblasts

artículo científico publicado en 2009

Caveolin-1-deficient aortic smooth muscle cells show cell autonomous abnormalities in proliferation, migration, and endothelin-based signal transduction

artículo científico publicado en 2006

Caveolin-1-deficient mice are lean, resistant to diet-induced obesity, and show hypertriglyceridemia with adipocyte abnormalities

artículo científico publicado en 2001

Caveolin-1-deficient mice show accelerated mammary gland development during pregnancy, premature lactation, and hyperactivation of the Jak-2/STAT5a signaling cascade.

artículo científico publicado en 2002

Caveolin-1-deficient mice show defects in innate immunity and inflammatory immune response during Salmonella enterica serovar Typhimurium infection

artículo científico publicado en 2006

Caveolin-1/3 double-knockout mice are viable, but lack both muscle and non-muscle caveolae, and develop a severe cardiomyopathic phenotype.

artículo científico publicado en 2002

Caveolin-2-deficient mice show increased sensitivity to endotoxemia

artículo científico publicado en 2011

Celecoxib combined with atorvastatin prevents progression of atherosclerosis

artículo científico publicado en 2010

Characterization of human apolipoprotein A-I expressed in Escherichia coli

artículo científico publicado en 1997

Cholesterol and breast cancer development.

artículo científico publicado en 2012

Clinical and translational implications of the caveolin gene family: lessons from mouse models and human genetic disorders

scientific article published on 30 March 2009

Deletion of central alpha-helices in human apolipoprotein A-I: effect on phospholipid association

artículo científico publicado en 1997

Deletion of the C-terminal domain of apolipoprotein A-I impairs cell surface binding and lipid efflux in macrophage

scientific article published on 01 November 1999

Development of a Novel High-Performance Thin Layer Chromatography-Based Method for the Simultaneous Quantification of Clinically Relevant Lipids from Cells and Tissue Extracts

scientific article published on 18 May 2020

Distinct central amphipathic alpha-helices in apolipoprotein A-I contribute to the in vivo maturation of high density lipoprotein by either activating lecithin-cholesterol acyltransferase or binding lipids

artículo científico publicado en 2000

EPA and DHA Fatty Acids Induce a Remodeling of Tumor Vasculature and Potentiate Docetaxel Activity

artículo científico publicado en 2020

Effect of apolipoprotein A-I lipidation on the formation and function of pre-beta and alpha-migrating LpA-I particles

artículo científico publicado en 1999

Effect of the surface lipid composition of reconstituted LPA-I on apolipoprotein A-I structure and lecithin: cholesterol acyltransferase activity

artículo científico publicado en 1998

Endothelial caveolae and caveolin-1 as key regulators of atherosclerosis

artículo científico publicado en 2010

Endothelial cells isolated from caveolin-2 knockout mice display higher proliferation rate and cell cycle progression relative to their wild-type counterparts

artículo científico publicado en 2009

Evolutionarily conserved role of calcineurin in phosphodegron-dependent degradation of phosphodiesterase 4D

artículo científico publicado en 2010

Genetic ablation of caveolin-1 confers protection against atherosclerosis

artículo científico publicado en 2003

Genetic ablation of caveolin-1 drives estrogen-hypersensitivity and the development of DCIS-like mammary lesions

artículo científico publicado en 2009

Heteronuclear NMR studies of human serum apolipoprotein A-I. Part I. Secondary structure in lipid-mimetic solution

artículo científico publicado en 2002

ICAM-1: role in inflammation and in the regulation of vascular permeability

artículo científico publicado en 2008

Impaired phagocytosis in caveolin-1 deficient macrophages

artículo científico publicado en 2005

Importance of central alpha-helices of human apolipoprotein A-I in the maturation of high-density lipoproteins

artículo científico publicado en 1998

Ketones and lactate "fuel" tumor growth and metastasis: Evidence that epithelial cancer cells use oxidative mitochondrial metabolism

artículo científico publicado en 2010

Loss of caveolin-1 causes the hyper-proliferation of intestinal crypt stem cells, with increased sensitivity to whole body gamma-radiation

artículo científico publicado en 2005

Loss of caveolin-3 induces a lactogenic microenvironment that is protective against mammary tumor formation

scientific journal article

Loss of stromal caveolin-1 leads to oxidative stress, mimics hypoxia and drives inflammation in the tumor microenvironment, conferring the "reverse Warburg effect": a transcriptional informatics analysis with validation

artículo científico publicado en 2010

Microvascular hyperpermeability in caveolin-1 (-/-) knock-out mice. Treatment with a specific nitric-oxide synthase inhibitor, L-NAME, restores normal microvascular permeability in Cav-1 null mice

artículo científico publicado en 2002

Muscle-specific interaction of caveolin isoforms: differential complex formation between caveolins in fibroblastic vs. muscle cells

artículo científico publicado en 2004

Oxidized Products of α-Linolenic Acid Negatively Regulate Cellular Survival and Motility of Breast Cancer Cells

scientific article published on 28 December 2019

Proteasome inhibitor (MG-132) treatment of mdx mice rescues the expression and membrane localization of dystrophin and dystrophin-associated proteins

artículo científico publicado en 2003

Role of caveolin-1 in the regulation of lipoprotein metabolism

artículo científico publicado en 2008

Role of caveolin-1 in the regulation of the vascular shear stress response

artículo científico publicado en 2006

Role of cholesterol in the development and progression of breast cancer

artículo científico publicado en 2010

SCN4B acts as a metastasis-suppressor gene preventing hyperactivation of cell migration in breast cancer

artículo científico publicado en 2016

SR-BI: Linking Cholesterol and Lipoprotein Metabolism with Breast and Prostate Cancer

artículo científico publicado en 2016

Seminal plasma choline phospholipid-binding proteins stimulate cellular cholesterol and phospholipid efflux

artículo científico publicado en 1999

Stabilization of caveolin-1 by cellular cholesterol and scavenger receptor class B type I.

artículo científico publicado en 2002

The autophagic tumor stroma model of cancer: Role of oxidative stress and ketone production in fueling tumor cell metabolism

artículo científico publicado en 2010

The reverse Warburg effect: aerobic glycolysis in cancer associated fibroblasts and the tumor stroma

artículo científico publicado en 2009

The reverse Warburg effect: glycolysis inhibitors prevent the tumor promoting effects of caveolin-1 deficient cancer associated fibroblasts

artículo científico publicado en 2010

Towards a new "stromal-based" classification system for human breast cancer prognosis and therapy

artículo científico publicado en 2009

Transcriptional evidence for the "Reverse Warburg Effect" in human breast cancer tumor stroma and metastasis: similarities with oxidative stress, inflammation, Alzheimer's disease, and "Neuron-Glia Metabolic Coupling"

artículo científico publicado en 2010

Lista de obras de Philippe G. Frank

A Western-type diet accelerates tumor progression in an autochthonous mouse model of prostate cancer

A biphasic response of hepatobiliary cholesterol metabolism to dietary fat at the onset of obesity in the mouse

ATR/TEM8 is highly expressed in epithelial cells lining Bacillus anthracis' three sites of entry: implications for the pathogenesis of anthrax infection

Ablation of calcineurin Aβ reveals hyperlipidemia and signaling cross-talks with phosphodiesterases

Adenovirus-mediated expression of caveolin-1 in mouse liver increases plasma high-density lipoprotein levels

Alterations in membrane caveolae and BKCa channel activity in skin fibroblasts in Smith-Lemli-Opitz syndrome

Altered emotionality, spatial memory and cholinergic function in caveolin-1 knock-out mice

Apolipoprotein A-I conformation in reconstituted discoidal lipoproteins varying in phospholipid and cholesterol content

Caveolin, caveolae, and endothelial cell function

Caveolin-1 (P132L), a common breast cancer mutation, confers mammary cell invasiveness and defines a novel stem cell/metastasis-associated gene signature

Caveolin-1 Null (−/−) Mice Show Dramatic Reductions in Life Span†

Caveolin-1 and caveolae in atherosclerosis: differential roles in fatty streak formation and neointimal hyperplasia

Caveolin-1 and regulation of cellular cholesterol homeostasis

Caveolin-1 deficiency stimulates neointima formation during vascular injury

Caveolin-1 expression negatively regulates cell cycle progression by inducing G(0)/G(1) arrest via a p53/p21(WAF1/Cip1)-dependent mechanism.

Caveolin-1 promotes tumor progression in an autochthonous mouse model of prostate cancer: genetic ablation of Cav-1 delays advanced prostate tumor development in tramp mice

Caveolin-1 regulates the anti-atherogenic properties of macrophages

Caveolin-1-/- null mammary stromal fibroblasts share characteristics with human breast cancer-associated fibroblasts

Caveolin-1-deficient aortic smooth muscle cells show cell autonomous abnormalities in proliferation, migration, and endothelin-based signal transduction

Caveolin-1-deficient mice are lean, resistant to diet-induced obesity, and show hypertriglyceridemia with adipocyte abnormalities

Caveolin-1-deficient mice show accelerated mammary gland development during pregnancy, premature lactation, and hyperactivation of the Jak-2/STAT5a signaling cascade.

Caveolin-1-deficient mice show defects in innate immunity and inflammatory immune response during Salmonella enterica serovar Typhimurium infection

Caveolin-1/3 double-knockout mice are viable, but lack both muscle and non-muscle caveolae, and develop a severe cardiomyopathic phenotype.

Caveolin-2-deficient mice show increased sensitivity to endotoxemia

Celecoxib combined with atorvastatin prevents progression of atherosclerosis

Characterization of human apolipoprotein A-I expressed in Escherichia coli

Cholesterol and breast cancer development.

Clinical and translational implications of the caveolin gene family: lessons from mouse models and human genetic disorders

Deletion of central alpha-helices in human apolipoprotein A-I: effect on phospholipid association

Deletion of the C-terminal domain of apolipoprotein A-I impairs cell surface binding and lipid efflux in macrophage

Development of a Novel High-Performance Thin Layer Chromatography-Based Method for the Simultaneous Quantification of Clinically Relevant Lipids from Cells and Tissue Extracts

Distinct central amphipathic alpha-helices in apolipoprotein A-I contribute to the in vivo maturation of high density lipoprotein by either activating lecithin-cholesterol acyltransferase or binding lipids

EPA and DHA Fatty Acids Induce a Remodeling of Tumor Vasculature and Potentiate Docetaxel Activity

Effect of apolipoprotein A-I lipidation on the formation and function of pre-beta and alpha-migrating LpA-I particles

Effect of the surface lipid composition of reconstituted LPA-I on apolipoprotein A-I structure and lecithin: cholesterol acyltransferase activity

Endothelial caveolae and caveolin-1 as key regulators of atherosclerosis

Endothelial cells isolated from caveolin-2 knockout mice display higher proliferation rate and cell cycle progression relative to their wild-type counterparts

Evolutionarily conserved role of calcineurin in phosphodegron-dependent degradation of phosphodiesterase 4D

Genetic ablation of caveolin-1 confers protection against atherosclerosis

Genetic ablation of caveolin-1 drives estrogen-hypersensitivity and the development of DCIS-like mammary lesions

Heteronuclear NMR studies of human serum apolipoprotein A-I. Part I. Secondary structure in lipid-mimetic solution

ICAM-1: role in inflammation and in the regulation of vascular permeability

Impaired phagocytosis in caveolin-1 deficient macrophages

Importance of central alpha-helices of human apolipoprotein A-I in the maturation of high-density lipoproteins

Ketones and lactate "fuel" tumor growth and metastasis: Evidence that epithelial cancer cells use oxidative mitochondrial metabolism

Loss of caveolin-1 causes the hyper-proliferation of intestinal crypt stem cells, with increased sensitivity to whole body gamma-radiation

Loss of caveolin-3 induces a lactogenic microenvironment that is protective against mammary tumor formation

Loss of stromal caveolin-1 leads to oxidative stress, mimics hypoxia and drives inflammation in the tumor microenvironment, conferring the "reverse Warburg effect": a transcriptional informatics analysis with validation

Microvascular hyperpermeability in caveolin-1 (-/-) knock-out mice. Treatment with a specific nitric-oxide synthase inhibitor, L-NAME, restores normal microvascular permeability in Cav-1 null mice

Muscle-specific interaction of caveolin isoforms: differential complex formation between caveolins in fibroblastic vs. muscle cells

Oxidized Products of α-Linolenic Acid Negatively Regulate Cellular Survival and Motility of Breast Cancer Cells

Proteasome inhibitor (MG-132) treatment of mdx mice rescues the expression and membrane localization of dystrophin and dystrophin-associated proteins

Role of caveolin-1 in the regulation of lipoprotein metabolism

Role of caveolin-1 in the regulation of the vascular shear stress response

Role of cholesterol in the development and progression of breast cancer

SCN4B acts as a metastasis-suppressor gene preventing hyperactivation of cell migration in breast cancer

SR-BI: Linking Cholesterol and Lipoprotein Metabolism with Breast and Prostate Cancer

Seminal plasma choline phospholipid-binding proteins stimulate cellular cholesterol and phospholipid efflux

Stabilization of caveolin-1 by cellular cholesterol and scavenger receptor class B type I.

The autophagic tumor stroma model of cancer: Role of oxidative stress and ketone production in fueling tumor cell metabolism

The reverse Warburg effect: aerobic glycolysis in cancer associated fibroblasts and the tumor stroma

The reverse Warburg effect: glycolysis inhibitors prevent the tumor promoting effects of caveolin-1 deficient cancer associated fibroblasts

Towards a new "stromal-based" classification system for human breast cancer prognosis and therapy

Transcriptional evidence for the "Reverse Warburg Effect" in human breast cancer tumor stroma and metastasis: similarities with oxidative stress, inflammation, Alzheimer's disease, and "Neuron-Glia Metabolic Coupling"