Lista de obras - Nekane Merino - Dominio Público Uruguay

A tumor-targeted trimeric 4-1BB-agonistic antibody induces potent anti-tumor immunity without systemic toxicity

scientific article published in Nature Communications

ATTACK, a novel bispecific T cell-recruiting antibody with trivalent EGFR binding and monovalent CD3 binding for cancer immunotherapy

artículo científico publicado en 2017

Bacterial secretion of soluble and functional trivalent scFv-based N-terminal trimerbodies.

artículo científico publicado en 2015

Carcinoembryonic Antigen (CEA)-Specific 4-1BB-Costimulation Induced by CEA-Targeted 4-1BB-Agonistic Trimerbodies

artículo científico publicado en 2019

Crystal Structure of the Homing Endonuclease I-CvuI Provides a New Template for Genome Modification.

artículo científico publicado en 2015

Crystallization and preliminary X-ray diffraction analysis of the homing endonuclease I-CvuI from Chlorella vulgaris in complex with its target DNA.

artículo científico publicado en 2014

Efficient targeting of a SCID gene by an engineered single-chain homing endonuclease

artículo científico publicado en 2009

Generation and characterization of monospecific and bispecific hexavalent trimerbodies

artículo científico publicado en 2012

Intramolecular trimerization, a novel strategy for making multispecific antibodies with controlled orientation of the antigen binding domains

artículo científico publicado en 2016

Molecular mechanism of Gαi activation by non-GPCR proteins with a Gα-Binding and Activating motif

artículo científico publicado en 2017

Structural basis of human PCNA sliding on DNA.

artículo científico publicado en 2017

Structure of the I-SceI nuclease complexed with its dsDNA target and three catalytic metal ions.

artículo científico publicado en 2016

Structure of the processive human Pol δ holoenzyme

scientific article published on 28 February 2020

The Gαi-GIV binding interface is a druggable protein-protein interaction

artículo científico publicado en 2017

The immunosuppressive effect of the tick protein, Salp15, is long-lasting and persists in a murine model of hematopoietic transplant

artículo científico publicado en 2017

Understanding the indirect DNA read-out specificity of I-CreI Meganuclease

artículo científico publicado en 2018

Lista de obras de Nekane Merino

A tumor-targeted trimeric 4-1BB-agonistic antibody induces potent anti-tumor immunity without systemic toxicity

ATTACK, a novel bispecific T cell-recruiting antibody with trivalent EGFR binding and monovalent CD3 binding for cancer immunotherapy

Bacterial secretion of soluble and functional trivalent scFv-based N-terminal trimerbodies.

Carcinoembryonic Antigen (CEA)-Specific 4-1BB-Costimulation Induced by CEA-Targeted 4-1BB-Agonistic Trimerbodies

Crystal Structure of the Homing Endonuclease I-CvuI Provides a New Template for Genome Modification.

Crystallization and preliminary X-ray diffraction analysis of the homing endonuclease I-CvuI from Chlorella vulgaris in complex with its target DNA.

Efficient targeting of a SCID gene by an engineered single-chain homing endonuclease

Generation and characterization of monospecific and bispecific hexavalent trimerbodies

Intramolecular trimerization, a novel strategy for making multispecific antibodies with controlled orientation of the antigen binding domains

Molecular mechanism of Gαi activation by non-GPCR proteins with a Gα-Binding and Activating motif

Structural basis of human PCNA sliding on DNA.

Structure of the I-SceI nuclease complexed with its dsDNA target and three catalytic metal ions.

Structure of the processive human Pol δ holoenzyme

The Gαi-GIV binding interface is a druggable protein-protein interaction

The immunosuppressive effect of the tick protein, Salp15, is long-lasting and persists in a murine model of hematopoietic transplant

Understanding the indirect DNA read-out specificity of I-CreI Meganuclease