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Lista de obras de Niels Jessen

5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside increases myocardial glucose uptake during reperfusion and induces late pre-conditioning: potential role of AMP-activated protein kinase.

artículo científico publicado en 2009

A PET Tracer for Renal Organic Cation Transporters, ¹¹C-Metformin: Radiosynthesis and Preclinical Proof-of-Concept Studies.

artículo científico publicado en 2016

A highly sensitive and specific assay for determination of IGF-I bioactivity in human serum

scientific article published on 25 February 2003

A novel insulin sensitizer (S15511) enhances insulin-stimulated glucose uptake in rat skeletal muscles

artículo científico publicado en 2008

A randomised, double-blind, placebo-controlled trial of metformin on myocardial efficiency in insulin-resistant chronic heart failure patients without diabetes

artículo científico publicado en 2019

A randomized placebo-controlled clinical trial of nicotinamide riboside in obese men: safety, insulin-sensitivity, and lipid-mobilizing effects

artículo científico publicado en 2018

AICAR stimulates adiponectin and inhibits cytokines in adipose tissue

artículo científico publicado en 2004

AMP kinase in exercise adaptation of skeletal muscle

artículo científico

AMP-activated protein kinase and the regulation of glucose transport

artículo científico publicado en 2006

AMPK vs mTORC1 signaling: genuine exercise effects of differentiated exercise in humans. Response to letter to editor by Dr A. K. Yamada

artículo científico publicado en 2012

AMPKα is critical for enhancing skeletal muscle fatty acid utilization during in vivo exercise in mice

artículo científico

Ablation of AMP-activated protein kinase alpha2 activity exacerbates insulin resistance induced by high-fat feeding of mice

artículo científico publicado en 2008

Ablation of LKB1 in the heart leads to energy deprivation and impaired cardiac function

artículo científico publicado en 2010

Acipimox Acutely Increases GLP-1 Concentrations in Overweight Subjects and Hypopituitary Patients

scientific article published on 01 July 2019

Acute Hypoglycemia in Healthy Humans Impairs Insulin-Stimulated Glucose Uptake and Glycogen Synthase in Skeletal Muscle: A Randomized Clinical Study.

artículo científico publicado en 2017

Acute and sustained effects of a periodized carbohydrate intake using the sleep-low model in endurance-trained males

artículo científico publicado en 2019

Acute peripheral metabolic effects of intraarterial ghrelin infusion in healthy young men.

artículo científico publicado en 2010

Acyl Ghrelin Induces Insulin Resistance Independently of GH, Cortisol, and Free Fatty Acids

artículo científico publicado en 2017

Altered gene expression and repressed markers of autophagy in skeletal muscle of insulin resistant patients with type 2 diabetes

artículo científico publicado en 2017

Amino acid supplementation is anabolic during the acute phase of endotoxin-induced inflammation: A human randomized crossover trial.

artículo científico publicado en 2015

Anabolic effects of leucine-rich whey protein, carbohydrate, and soy protein with and without β-hydroxy-β-methylbutyrate (HMB) during fasting-induced catabolism: A human randomized crossover trial

artículo científico publicado en 2016

Assessment of mouse liver [1-13C]pyruvate metabolism by dynamic hyperpolarized MRS

scientific article published on 01 September 2019

Assessment of the cardiovascular and gastrointestinal autonomic complications of diabetes

artículo científico publicado en 2016

CaMKII regulates contraction- but not insulin-induced glucose uptake in mouse skeletal muscle

artículo científico publicado en 2010

Cardiac vagal tone, a non-invasive measure of parasympathetic tone, is a clinically relevant tool in Type 1 diabetes mellitus

artículo científico publicado en 2017

Changes in adipokines after transjugular intrahepatic porto-systemic shunt indicate an anabolic shift in metabolism

artículo científico publicado en 2012

Chronic adrenergic stimulation induces brown adipose tissue differentiation in visceral adipose tissue.

artículo científico publicado en 2015

Chronic consumption of farmed salmon containing persistent organic pollutants causes insulin resistance and obesity in mice ⬇️

artículo científico publicado en 2011

Clinical Pharmacology in Denmark in 2016 - 40 Years with the Danish Society of Clinical Pharmacology and 20 Years as a Medical Speciality

artículo científico publicado en 2016

Combined Insulin Deficiency and Endotoxin Exposure Stimulate Lipid Mobilization and Alter Adipose Tissue Signaling in an Experimental Model of Ketoacidosis in Subjects With Type 1 Diabetes: A Randomized Controlled Crossover Trial

artículo científico publicado en 2016

Contraction signaling to glucose transport in skeletal muscle

artículo científico publicado en 2005

Defects in muscle branched-chain amino acid oxidation contribute to impaired lipid metabolism

scientific article published on 06 August 2016

Delaying time to first nocturnal void may have beneficial effects on reducing blood glucose levels.

artículo científico publicado en 2016

Diabetes: Exercise and type 2 diabetes mellitus--good for body and mind?

artículo científico publicado en 2010

Differential regulation of lipid and protein metabolism in obese vs. lean subjects before and after a 72-h fast

artículo científico publicado en 2016

Differentiated mTOR but not AMPK signaling after strength vs endurance exercise in training-accustomed individuals.

artículo científico publicado en 2013

Direct effects of TNF-α on local fuel metabolism and cytokine levels in the placebo-controlled, bilaterally infused human leg: increased insulin sensitivity, increased net protein breakdown, and increased IL-6 release.

artículo científico publicado en 2013

Direct effects of locally administered lipopolysaccharide on glucose, lipid, and protein metabolism in the placebo-controlled, bilaterally infused human leg.

artículo científico publicado en 2013

Dissecting adipose tissue lipolysis: molecular regulation and implications for metabolic disease

artículo científico publicado en 2014

Distinct signals regulate AS160 phosphorylation in response to insulin, AICAR, and contraction in mouse skeletal muscle

artículo científico publicado en 2006

Dose-response effects of free fatty acids on glucose and lipid metabolism during somatostatin blockade of growth hormone and insulin in humans

artículo científico publicado en 2007

Effect of resveratrol on experimental non-alcoholic fatty liver disease depends on severity of pathology and timing of treatment.

artículo científico publicado en 2015

Effect of resveratrol on experimental non-alcoholic steatohepatitis.

artículo científico publicado en 2015

Effects of 3-hydroxybutyrate and free fatty acids on muscle protein kinetics and signaling during LPS-induced inflammation in humans: anticatabolic impact of ketone bodies

scientific article published on 01 October 2018

Effects of AICAR and exercise on insulin-stimulated glucose uptake, signaling, and GLUT-4 content in rat muscles

artículo científico publicado en 2002

Effects of Nicotinamide Riboside on Endocrine Pancreatic Function and Incretin Hormones in Nondiabetic Men With Obesity

artículo científico publicado en 2019

Effects of Prednisolone on Serum and Tissue Fluid IGF-I Receptor Activation and Post-Receptor Signaling in Humans.

artículo científico publicado en 2017

Effects of divergent resistance exercise contraction mode and dietary supplementation type on anabolic signalling, muscle protein synthesis and muscle hypertrophy

artículo científico publicado en 2014

Effects of exercise training on subcutaneous and visceral adipose tissue in normal- and high-fat diet-fed rats

scientific article published on 02 June 2009

Effects of insulin-induced hypoglycaemia on lipolysis rate, lipid oxidation and adipose tissue signalling in human volunteers: a randomised clinical study.

artículo científico publicado en 2016

Effects of short-term prednisolone treatment on indices of lipolysis and lipase signaling in abdominal adipose tissue in healthy humans

scientific article published on 29 June 2019

Endogenous peroxisome proliferator-activated receptor-gamma augments fatty acid uptake in oxidative muscle

artículo científico publicado en 2008

Enrichment of Genetic Variants in the Glucocorticoid Receptor Signalling Pathway in Autoimmune Hepatitis with Failure of Standard Treatment

artículo científico publicado en 2017

Erythropoietin administration acutely stimulates resting energy expenditure in healthy young men.

artículo científico publicado en 2012

Erythropoietin does not activate erythropoietin receptor signaling or lipolytic pathways in human subcutaneous white adipose tissue in vivo.

artículo científico publicado en 2016

Evaluation of Active Brown Adipose Tissue by the Use of Hyperpolarized [1-C]Pyruvate MRI in Mice

scientific article published on 01 September 2018

Evaluation of functional erythropoietin receptor status in skeletal muscle in vivo: acute and prolonged studies in healthy human subjects

artículo científico publicado en 2012

Evidence against a role for insulin-signaling proteins PI 3-kinase and Akt in insulin resistance in human skeletal muscle induced by short-term GH infusion

artículo científico publicado en 2004

Exercise and fasting activate growth hormone-dependent myocellular signal transducer and activator of transcription-5b phosphorylation and insulin-like growth factor-I messenger ribonucleic acid expression in humans.

artículo científico publicado en 2010

Exercise increases TBC1D1 phosphorylation in human skeletal muscle

artículo científico publicado en 2011

Experimental nonalcoholic steatohepatitis compromises ureagenesis, an essential hepatic metabolic function

artículo científico publicado en 2014

FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis

artículo científico publicado en 2020

Fasting increases human skeletal muscle net phenylalanine release and this is associated with decreased mTOR signaling

artículo científico publicado en 2014

Fasting, but not exercise, increases adipose triglyceride lipase (ATGL) protein and reduces G(0)/G(1) switch gene 2 (G0S2) protein and mRNA content in human adipose tissue

artículo científico publicado en 2011

Fat content in liver and skeletal muscle changes in a reciprocal manner in patients with acromegaly during combination therapy with a somatostatin analog and a GH receptor antagonist: a randomized clinical trial

artículo científico publicado en 2012

Free Fatty Acids Inhibit Growth Hormone/Signal Transducer and Activator of Transcription-5 Signaling in Human Muscle: A Potential Feedback Mechanism.

artículo científico publicado en 2009

Free fatty acids inhibit growth hormone/signal transducer and activator of transcription-5 signaling in human muscle: a potential feedback mechanism.

artículo científico publicado en 2009

GH receptor signaling in skeletal muscle and adipose tissue in human subjects following exposure to an intravenous GH bolus

artículo científico publicado en 2006

GH signaling in human adipose and muscle tissue during 'feast and famine': amplification of exercise stimulation following fasting compared to glucose administration

artículo científico publicado en 2015

GH signaling in skeletal muscle and adipose tissue in healthy human subjects: impact of gender and age

artículo científico publicado en 2014

GLUT4 and UBC9 protein expression is reduced in muscle from type 2 diabetic patients with severe insulin resistance.

artículo científico publicado en 2011

Gene expression in skeletal muscle after an acute intravenous GH bolus in human subjects: identification of a mechanism regulating ANGPTL4.

artículo científico publicado en 2013

Genetic Polymorphisms in Organic Cation Transporter 1 Attenuates Hepatic Metformin Exposure in Humans.

artículo científico publicado en 2017

Ghrelin infusion in humans induces acute insulin resistance and lipolysis independent of growth hormone signaling

artículo científico publicado en 2008

Ghrelin- and GH-induced insulin resistance: no association with retinol-binding protein-4.

artículo científico publicado en 2013

Growth Hormone and Insulin Signaling in Acromegaly: Impact of Surgery Versus Somatostatin Analog Treatment

artículo científico publicado en 2016

Growth hormone (GH)-induced insulin resistance is rapidly reversible: an experimental study in GH-deficient adults

artículo científico publicado en 2011

Growth hormone acts along PPARγ-FSP27 axis to stimulate lipolysis in human adipocytes

artículo científico publicado en 2018

Growth hormone and glucose homeostasis

artículo científico publicado en 2004

Growth hormone controls lipolysis by regulation of FSP27 expression

artículo científico publicado en 2018

Growth hormone signaling and action in obese versus lean human subjects

artículo científico publicado en 2018

Growth hormone signaling in muscle and adipose tissue of obese human subjects: associations with measures of body composition and interaction with resveratrol treatment

artículo científico publicado en 2014

Growth hormone signaling in vivo in human muscle and adipose tissue: impact of insulin, substrate background, and growth hormone receptor blockade.

artículo científico publicado en 2008

Growth hormone upregulates ANGPTL4 mRNA and suppresses lipoprotein lipase via fatty acids: Randomized experiments in human individuals

artículo científico publicado en 2020

Growth hormone-induced insulin resistance in human subjects involves reduced pyruvate dehydrogenase activity.

artículo científico publicado en 2013

Hepatic exposure of metformin in patients with non-alcoholic fatty liver disease

artículo científico publicado en 2019

High expression of organic cation transporter 3 in human BAT-like adipocytes. Implications for extraneuronal norepinephrine uptake

artículo científico publicado en 2016

High-dose resveratrol supplementation in obese men: an investigator-initiated, randomized, placebo-controlled clinical trial of substrate metabolism, insulin sensitivity, and body composition.

artículo científico publicado en 2012

Human skeletal muscle CD90<sup>+</sup> fibro-adipogenic progenitors are associated with muscle degeneration in type 2 diabetic patients

artículo científico publicado en 2021

Hyperpolarized [1- C] pyruvate as a possible diagnostic tool in liver disease

artículo científico publicado en 2018

IL-6 has no acute effect on the regulation of urea synthesisin vivoin rats

artículo científico publicado en 2010

Imaging in Pharmacogenetics

artículo científico publicado en 2018

Immobilization Decreases FOXO3a Phosphorylation and Increases Autophagy-Related Gene and Protein Expression in Human Skeletal Muscle.

artículo científico publicado en 2019

Impact of growth hormone receptor blockade on substrate metabolism during fasting in healthy subjects

artículo científico publicado en 2009

Impaired insulin action despite upregulation of proximal insulin signaling: novel insights into skeletal muscle insulin resistance in liver cirrhosis

scientific article published on 28 September 2006

In Vivo Imaging of Human 11C-Metformin in Peripheral Organs: Dosimetry, Biodistribution, and Kinetic Analyses.

artículo científico publicado en 2016

Independent effects of testosterone on lipid oxidation and VLDL-TG production: a randomized, double-blind, placebo-controlled, crossover study

artículo científico publicado en 2012

Insulin and GH signaling in human skeletal muscle in vivo following exogenous GH exposure: impact of an oral glucose load

artículo científico publicado en 2011

Insulin inhibits autophagy signaling independent of counter-regulatory hormone levels, but does not affect the effects of exercise

artículo científico publicado en 2018

Insulin resistance after a 72-h fast is associated with impaired AS160 phosphorylation and accumulation of lipid and glycogen in human skeletal muscle.

artículo científico publicado en 2011

Insulin resistance induced by growth hormone is linked to lipolysis and associated with suppressed pyruvate dehydrogenase activity in skeletal muscle: a 2 × 2 factorial, randomised, crossover study in human individuals

scientific article published on 18 September 2020

Intact pituitary function is decisive for the catabolic response to TNF-α: studies of protein, glucose and fatty acid metabolism in hypopituitary and healthy subjects

artículo científico publicado en 2014

JNK1 deficiency does not enhance muscle glucose metabolism in lean mice

artículo científico publicado en 2006

Ketone Body Infusion With 3-Hydroxybutyrate Reduces Myocardial Glucose Uptake and Increases Blood Flow in Humans: A Positron Emission Tomography Study

artículo científico publicado en 2017

Kinetics and utilization of lipid sources during acute exercise and acipimox

artículo científico publicado en 2014

LKB1 regulates lipid oxidation during exercise independently of AMPK

artículo científico publicado en 2013

LPS-Enhanced Glucose-Stimulated Insulin Secretion Is Normalized by Resveratrol

artículo científico publicado en 2016

Long-term AICAR administration and exercise prevents diabetes in ZDF rats

artículo científico publicado en 2005

Long-term AICAR administration reduces metabolic disturbances and lowers blood pressure in rats displaying features of the insulin resistance syndrome

artículo científico publicado en 2002

Macrophage activation marker sCD163 correlates with accelerated lipolysis following LPS exposure: a human-randomised clinical trial

artículo científico publicado en 2018

Maternal protein restriction before pregnancy reduces offspring early body mass and affects glucose metabolism in C57BL/6JBom mice

artículo científico publicado en 2012

Metabolic effects of insulin in a human model of ketoacidosis combining exposure to lipopolysaccharide and insulin deficiency: a randomised, controlled, crossover study in individuals with type 1 diabetes

artículo científico publicado en 2017

Metabolic impacts of high dietary exposure to persistent organic pollutants in mice

artículo científico publicado en 2012

Metformin Lowers Body Weight But Fails to Increase Insulin Sensitivity in Chronic Heart Failure Patients without Diabetes: a Randomized, Double-Blind, Placebo-Controlled Study

artículo científico publicado en 2020

Metformin does not Affect Postabsorptive Hepatic Free Fatty Acid Uptake, Oxidation or Resecretion in Humans: A 3-months Placebo Controlled Clinical Trial in Patients with Type 2 Diabetes and Healthy Controls

artículo científico publicado en 2018

Metformin increases endogenous glucose production in non-diabetic individuals and individuals with recent-onset type 2 diabetes

artículo científico publicado en 2019

Metformin induces cardioprotection against ischaemia/reperfusion injury in the rat heart 24 hours after administration

artículo científico publicado en 2008

Metformin is distributed to tumor tissue in breast cancer patients in vivo: A 11C-metformin PET/CT study

scientific article published on 02 April 2020

Metformin reduces liver glucose production by inhibition of fructose-1-6-bisphosphatase ⬇️

artículo científico publicado en 2018

Metformin targets brown adipose tissue in vivo and reduces oxygen consumption in vitro

artículo científico publicado en 2018

Microarray expression analysis in delayed cardioprotection: the effect of exercise, AICAR, or metformin and the possible role of AMP-activated protein kinase (AMPK).

artículo científico publicado en 2011

Molecular and cellular adaptations to exercise training in skeletal muscle from cancer patients treated with chemotherapy

scientific article published on 09 April 2019

Nicotinamide riboside does not alter mitochondrial respiration, content or morphology in skeletal muscle from obese and insulin-resistant men

artículo científico publicado en 2019

No Beneficial Effects of Resveratrol on the Metabolic Syndrome: A Randomized Placebo-Controlled Clinical Trial

artículo científico publicado en 2017

Novel serum biomarkers for erythropoietin use in humans: a proteomic approach.

artículo científico publicado en 2010

Physical exercise increases autophagic signaling through ULK1 in human skeletal muscle

artículo científico publicado en 2015

Placebo-controlled, randomised clinical trial: high-dose resveratrol treatment for non-alcoholic fatty liver disease

artículo científico publicado en 2016

Placental superoxide dismutase 3 mediates benefits of maternal exercise on offspring health

artículo científico publicado en 2021

Prolonged erythropoietin treatment does not impact gene expression in human skeletal muscle

artículo científico publicado en 2015

Prolonged fasting-induced metabolic signatures in human skeletal muscle of lean and obese men

artículo científico publicado en 2018

Pronounced expression of the lipolytic inhibitor G0/G1 Switch Gene 2 (G0S2) in adipose tissue from brown bears (Ursus arctos) prior to hibernation

artículo científico publicado en 2016

Reduced CD300LG mRNA tissue expression, increased intramyocellular lipid content and impaired glucose metabolism in healthy male carriers of Arg82Cys in CD300LG: a novel genometabolic cross-link between CD300LG and common metabolic phenotypes

artículo científico publicado en 2015

Reduced cannabinoid receptor 1 protein in subcutaneous adipose tissue of obese

artículo científico publicado en 2009

Reduced mRNA and protein expression of perilipin A and G0/G1 switch gene 2 (G0S2) in human adipose tissue in poorly controlled type 2 diabetes

artículo científico publicado en 2012

Redundancy in regulation of lipid accumulation in skeletal muscle during prolonged fasting in obese men

scientific article published on 01 November 2019

Regulation of Lipolysis and Adipose Tissue Signaling during Acute Endotoxin-Induced Inflammation: A Human Randomized Crossover Trial.

artículo científico publicado en 2016

Regulation of urea synthesis during the acute-phase response in rats

artículo científico publicado en 2013

Renal PET-imaging with (11)C-metformin in a transgenic mouse model for chronic kidney disease.

artículo científico publicado en 2016

Renoprotective Effects of Metformin are Independent of Organic Cation Transporters 1 &2 and AMP-activated Protein Kinase in the Kidney

artículo científico publicado en 2016

Reply: Letter to the editor - A dietary amino acid load causes a transient decrease in the function of human neutrophil granulocytes

artículo científico publicado en 2016

Resistance exercise, but not endurance exercise, induces IKKβ phosphorylation in human skeletal muscle of training-accustomed individuals

artículo científico publicado en 2013

Results from 11C-metformin-PET scans, tissue analysis and cellular drug-sensitivity assays questions the view that biguanides affects tumor respiration directly.

artículo científico

Resveratrol ameliorates imiquimod-induced psoriasis-like skin inflammation in mice

artículo científico publicado en 2015

Resveratrol in metabolic health: an overview of the current evidence and perspectives.

artículo científico publicado en 2013

Resveratrol up-regulates hepatic uncoupling protein 2 and prevents development of nonalcoholic fatty liver disease in rats fed a high-fat diet.

artículo científico publicado en 2012

SLC30A3 responds to glucose- and zinc variations in beta-cells and is critical for insulin production and in vivo glucose-metabolism during beta-cell stress.

artículo científico publicado en 2009

Sevoflurane Impairs Insulin Secretion and Tissue-Specific Glucose Uptake In Vivo

scientific article published on 24 August 2018

Single-centre experience of the macrophage activation marker soluble (s)CD163 - associations with disease activity and treatment response in patients with autoimmune hepatitis.

artículo científico publicado en 2016

Skeletal muscle-selective knockout of LKB1 increases insulin sensitivity, improves glucose homeostasis, and decreases TRB3

artículo científico publicado en 2006

Soluble programmed death-1 levels are associated with disease activity and treatment response in patients with autoimmune hepatitis.

artículo científico publicado en 2016

Stress hormone release is a key component of the metabolic response to lipopolysaccharide: studies in hypopituitary and healthy subjects

artículo científico publicado en 2016

Substrate Metabolism and Insulin Sensitivity During Fasting in Obese Human Subjects: Impact of GH Blockade

artículo científico publicado en 2017

Substrate metabolism, hormone and cytokine levels and adipose tissue signalling in individuals with type 1 diabetes after insulin withdrawal and subsequent insulin therapy to model the initiating steps of ketoacidosis

artículo científico publicado en 2018

Sustained AS160 and TBC1D1 phosphorylations in human skeletal muscle 30 min after a single bout of exercise.

artículo científico publicado en 2014

Temporal patterns of lipolytic regulators in adipose tissue after acute growth hormone exposure in human subjects: A randomized controlled crossover trial

scientific article published on 20 August 2019

The acute effect of a physiological bolus of growth hormone (GH) on insulin signalling pathways in striated muscle in healthy volunteers.

artículo científico publicado en 2009

The acute effects of growth hormone in adipose tissue is associated with suppression of antilipolytic signals

artículo científico publicado en 2020

The effect of exercise, training, and inactivity on insulin sensitivity in diabetics and their relatives: what is new?

artículo científico publicado en 2007

Time-course effects of physiological free fatty acid surges on insulin sensitivity in humans

scientific article published on 11 October 2010

Treatment with an SSRI antidepressant restores hippocampo-hypothalamic corticosteroid feedback and reverses insulin resistance in low-birth-weight rats

artículo científico publicado en 2010

Type 2 diabetes mellitus worsens neurological injury following cardiac arrest: an animal experimental study

scientific article published on 07 August 2018

Unacylated Ghrelin Does Not Acutely Affect Substrate Metabolism or Insulin Sensitivity in Men With Type 2 Diabetes

scientific article published on 01 June 2019

Unchanged capacity of urea synthesis during acute phase response in rats

scientific article published on 19 August 2010

Underpowered or negative? A crucial distinction

artículo científico publicado en 2019

Whole body metabolic effects of prolonged endurance training in combination with erythropoietin treatment in humans: a randomized placebo controlled trial

artículo científico publicado en 2013

[11C]-Labeled Metformin Distribution in the Liver and Small Intestine Using Dynamic Positron Emission Tomography in Mice Demonstrates Tissue-Specific Transporter Dependency.

artículo científico publicado en 2016

miRNAs in human subcutaneous adipose tissue: Effects of weight loss induced by hypocaloric diet and exercise.

artículo científico publicado en 2017

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016

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