Lista de obras - Wei Huang - Dominio Público Uruguay

A Concise Synthesis of Three Branches Derived from Polysaccharide RN1 and Anti-Pancreatic Cancer Activity Study

scientific article published on 21 October 2017

A Traceless Site‐Specific Conjugation on Native Antibodies Enables Efficient One‐Step Payload Assembly

artículo científico publicado en 2022

A combined method for producing homogeneous glycoproteins with eukaryotic N-glycosylation

artículo científico publicado en 2010

A simplified procedure for gram-scale production of sialylglycopeptide (SGP) from egg yolks and subsequent semi-synthesis of Man3GlcNAc oxazoline

artículo científico publicado en 2014

Anti-Oligomannose Antibodies as Potential Serum Biomarkers of Aggressive Prostate Cancer

artículo científico publicado en 2013

Antibody against Microbial Neuraminidases Recognizes Human Sialidase 3 (NEU3): the Neuraminidase/Sialidase Superfamily Revisited.

artículo científico publicado en 2017

Arthrobacter endo-beta-N-acetylglucosaminidase shows transglycosylation activity on complex-type N-glycan oxazolines: one-pot conversion of ribonuclease B to sialylated ribonuclease C.

artículo científico publicado en 2010

Biochemical features of the adhesion G protein-coupled receptor CD97 related to its auto-proteolysis and HeLa cell attachment activities.

artículo científico publicado en 2016

Chemical Synthesis of the Homogeneous Granulocyte-Macrophage Colony-Stimulating Factor Through Se-Auxiliary-Mediated Ligation

scientific article published on 16 December 2019

Chemoenzymatic glycoengineering of intact IgG antibodies for gain of functions.

artículo científico publicado en 2012

Chemoenzymatic synthesis and Fcγ receptor binding of homogeneous glycoforms of antibody Fc domain. Presence of a bisecting sugar moiety enhances the affinity of Fc to FcγIIIa receptor

artículo científico publicado en 2011

Chemoenzymatic synthesis and lectin array characterization of a class of N-glycan clusters.

artículo científico publicado en 2009

Chemoenzymatic synthesis and lectin recognition of a selectively fluorinated glycoprotein ⬇️

artículo científico publicado el 21 de marzo de 2013

Chemoenzymatic synthesis of N-linked neoglycoproteins through a chitinase-catalyzed transglycosylation.

artículo científico publicado en 2008

Chemoenzymatic synthesis of glycoengineered IgG antibodies and glycosite-specific antibody-drug conjugates.

artículo científico publicado en 2017

Convergent Synthesis of Homogeneous Glc1Man9GlcNAc2-Protein and Derivatives as Ligands of Molecular Chaperones in Protein Quality Control ⬇️

artículo científico publicado el 19 de agosto de 2011

Core Fucosylation of Maternal Milk N-Glycan Evokes B Cell Activation by Selectively Promoting the l-Fucose Metabolism of Gut spp. and spp

scientific article published on 02 April 2019

Design and Synthesis of Pyrophosphate-Targeting Vancomycin Derivatives for Combating Vancomycin-Resistant Enterococci

artículo científico publicado en 2018

Design and synthesis of glycoprotein-based multivalent glyco-ligands for influenza hemagglutinin and human galectin-3 ⬇️

artículo científico publicado el 23 de enero de 2013

Design and synthesis of novel dual-cyclic RGD peptides for αvβ3 integrin targeting

artículo científico publicado en 2019

Efficient glycosynthase mutant derived from Mucor hiemalis endo-beta-N-acetylglucosaminidase capable of transferring oligosaccharide from both sugar oxazoline and natural N-glycan

artículo científico publicado en 2009

Efficient transfer of sialo-oligosaccharide onto proteins by combined use of a glycosynthase-like mutant of Mucor hiemalis endoglycosidase and synthetic sialo-complex-type sugar oxazoline

artículo científico publicado en 2010

Endo-beta-N-acetylglucosaminidase-catalyzed polymerization of beta-Glcp-(1-->4)-GlcpNAc oxazoline: a revisit to enzymatic transglycosylation

artículo científico publicado en 2009

Enzymatic glycosylation of triazole-linked GlcNAc/Glc-peptides: synthesis, stability and anti-HIV activity of triazole-linked HIV-1 gp41 glycopeptide C34 analogues.

scientific article published on May 2009

Epitopes of MUC1 Tandem Repeats in Cancer as Revealed by Antibody Crystallography: Toward Glycopeptide Signature-Guided Therapy

artículo científico publicado en 2018

Expeditious chemoenzymatic synthesis of CD52 glycopeptide antigens.

artículo científico publicado en 2010

Expression, glycoform characterization, and antibody-binding of HIV-1 V3 glycopeptide domain fused with human IgG1-Fc

artículo científico publicado en 2010

Extra Sugar on Vancomycin: New Analogues for Combating Multidrug-Resistant Staphylococcus aureus and Vancomycin-Resistant Enterococci.

artículo científico publicado en 2017

FK506-binding protein ligands: structure-based design, synthesis, and neurotrophic/neuroprotective properties of substituted 5,5-dimethyl-2-(4-thiazolidine)carboxylates

artículo científico publicado en 2006

Glycoconjugate probes containing a core-fucosylated N-glycan trisaccharide for fucose lectin identification and purification

scientific article published on 03 August 2017

Glycoengineering and glycosite-specific labeling of serum IgGs from various species.

artículo científico publicado en 2017

Glycosynthases enable a highly efficient chemoenzymatic synthesis of N-glycoproteins carrying intact natural N-glycans

artículo científico publicado en 2009

Homogeneous Antibody-Drug Conjugates via Glycoengineering

scientific article published on 01 January 2019

Introducing N-glycans into natural products through a chemoenzymatic approach.

artículo científico publicado en 2008

Molecular basis of antibody binding to mucin glycopeptides in lung cancer

artículo científico publicado en 2015

N-glycosylation of the β2 adrenergic receptor regulates receptor function by modulating dimerization

artículo científico publicado en 2017

NEU1 and NEU3 sialidase activity expressed in human lung microvascular endothelia: NEU1 restrains endothelial cell migration, whereas NEU3 does not

artículo científico publicado en 2012

One-step immobilization and purification of genetic engineering CBD fusion EndoS on cellulose for antibodies Fc-glycan remodeling

scientific article published on 12 July 2019

Palladium-Catalysed C(sp3 )-H Glycosylation for the Synthesis of C-Alkyl Glycoamino Acids

artículo científico publicado en 2020

Real-Time Analysis on Drug-Antibody Ratio of Antibody-Drug Conjugates for Synthesis, Process Optimization, and Quality Control

artículo científico publicado en 2017

Remarkable transglycosylation activity of glycosynthase mutants of endo-D, an endo-β-N-acetylglucosaminidase from Streptococcus pneumoniae.

artículo científico publicado en 2012

Selective N-glycan editing on living cell surfaces to probe glycoconjugate function

artículo científico publicado en 2020

Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage

artículo científico publicado en 2014

Structure-Based Discovery of a Subtype-Selective Inhibitor Targeting a Transient Receptor Potential Vanilloid Channel

scientific article published on 16 January 2019

Sulfonium, an Underestimated Moiety for Structural Modification, Alters the Antibacterial Profile of Vancomycin Against Multidrug-Resistant Bacteria

scientific article published on 09 April 2019

Synthesis and biological activity of metabolically stabilized cyclopentyl trisphosphate analogues of D-myo-Ins(1,4,5)P3.

artículo científico publicado en 2007

Synthesis of Branched Peptides via a Side-Chain Benzyl Ester

artículo científico publicado en 2020

Synthetic glycopeptides reveal the glycan specificity of HIV-neutralizing antibodies.

artículo científico publicado en 2013

Thermostability detection and optimization of glycoengineered antibodies and antibody-drug conjugates based on differential scanning flouremitry analysis

artículo científico publicado en 2019

Uncovering cryptic glycan markers in multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE).

artículo científico publicado en 2014

Unusual transglycosylation activity of Flavobacterium meningosepticum endoglycosidases enables convergent chemoenzymatic synthesis of core fucosylated complex N-glycopeptides

artículo científico publicado en 2011

Lista de obras de Wei Huang

A Concise Synthesis of Three Branches Derived from Polysaccharide RN1 and Anti-Pancreatic Cancer Activity Study

A Traceless Site‐Specific Conjugation on Native Antibodies Enables Efficient One‐Step Payload Assembly

A combined method for producing homogeneous glycoproteins with eukaryotic N-glycosylation

A simplified procedure for gram-scale production of sialylglycopeptide (SGP) from egg yolks and subsequent semi-synthesis of Man3GlcNAc oxazoline

Anti-Oligomannose Antibodies as Potential Serum Biomarkers of Aggressive Prostate Cancer

Antibody against Microbial Neuraminidases Recognizes Human Sialidase 3 (NEU3): the Neuraminidase/Sialidase Superfamily Revisited.

Arthrobacter endo-beta-N-acetylglucosaminidase shows transglycosylation activity on complex-type N-glycan oxazolines: one-pot conversion of ribonuclease B to sialylated ribonuclease C.

Biochemical features of the adhesion G protein-coupled receptor CD97 related to its auto-proteolysis and HeLa cell attachment activities.

Chemical Synthesis of the Homogeneous Granulocyte-Macrophage Colony-Stimulating Factor Through Se-Auxiliary-Mediated Ligation

Chemoenzymatic glycoengineering of intact IgG antibodies for gain of functions.

Chemoenzymatic synthesis and Fcγ receptor binding of homogeneous glycoforms of antibody Fc domain. Presence of a bisecting sugar moiety enhances the affinity of Fc to FcγIIIa receptor

Chemoenzymatic synthesis and lectin array characterization of a class of N-glycan clusters.

Chemoenzymatic synthesis and lectin recognition of a selectively fluorinated glycoprotein ⬇️

Chemoenzymatic synthesis of N-linked neoglycoproteins through a chitinase-catalyzed transglycosylation.

Chemoenzymatic synthesis of glycoengineered IgG antibodies and glycosite-specific antibody-drug conjugates.

Convergent Synthesis of Homogeneous Glc1Man9GlcNAc2-Protein and Derivatives as Ligands of Molecular Chaperones in Protein Quality Control ⬇️

Core Fucosylation of Maternal Milk N-Glycan Evokes B Cell Activation by Selectively Promoting the l-Fucose Metabolism of Gut spp. and spp

Design and Synthesis of Pyrophosphate-Targeting Vancomycin Derivatives for Combating Vancomycin-Resistant Enterococci

Design and synthesis of glycoprotein-based multivalent glyco-ligands for influenza hemagglutinin and human galectin-3 ⬇️

Design and synthesis of novel dual-cyclic RGD peptides for αvβ3 integrin targeting

Efficient glycosynthase mutant derived from Mucor hiemalis endo-beta-N-acetylglucosaminidase capable of transferring oligosaccharide from both sugar oxazoline and natural N-glycan

Efficient transfer of sialo-oligosaccharide onto proteins by combined use of a glycosynthase-like mutant of Mucor hiemalis endoglycosidase and synthetic sialo-complex-type sugar oxazoline

Endo-beta-N-acetylglucosaminidase-catalyzed polymerization of beta-Glcp-(1-->4)-GlcpNAc oxazoline: a revisit to enzymatic transglycosylation

Enzymatic glycosylation of triazole-linked GlcNAc/Glc-peptides: synthesis, stability and anti-HIV activity of triazole-linked HIV-1 gp41 glycopeptide C34 analogues.

Epitopes of MUC1 Tandem Repeats in Cancer as Revealed by Antibody Crystallography: Toward Glycopeptide Signature-Guided Therapy

Expeditious chemoenzymatic synthesis of CD52 glycopeptide antigens.

Expression, glycoform characterization, and antibody-binding of HIV-1 V3 glycopeptide domain fused with human IgG1-Fc

Extra Sugar on Vancomycin: New Analogues for Combating Multidrug-Resistant Staphylococcus aureus and Vancomycin-Resistant Enterococci.

FK506-binding protein ligands: structure-based design, synthesis, and neurotrophic/neuroprotective properties of substituted 5,5-dimethyl-2-(4-thiazolidine)carboxylates

Glycoconjugate probes containing a core-fucosylated N-glycan trisaccharide for fucose lectin identification and purification

Glycoengineering and glycosite-specific labeling of serum IgGs from various species.

Glycosynthases enable a highly efficient chemoenzymatic synthesis of N-glycoproteins carrying intact natural N-glycans

Homogeneous Antibody-Drug Conjugates via Glycoengineering

Introducing N-glycans into natural products through a chemoenzymatic approach.

Molecular basis of antibody binding to mucin glycopeptides in lung cancer

N-glycosylation of the β2 adrenergic receptor regulates receptor function by modulating dimerization

NEU1 and NEU3 sialidase activity expressed in human lung microvascular endothelia: NEU1 restrains endothelial cell migration, whereas NEU3 does not

One-step immobilization and purification of genetic engineering CBD fusion EndoS on cellulose for antibodies Fc-glycan remodeling

Palladium-Catalysed C(sp3 )-H Glycosylation for the Synthesis of C-Alkyl Glycoamino Acids

Real-Time Analysis on Drug-Antibody Ratio of Antibody-Drug Conjugates for Synthesis, Process Optimization, and Quality Control

Remarkable transglycosylation activity of glycosynthase mutants of endo-D, an endo-β-N-acetylglucosaminidase from Streptococcus pneumoniae.

Selective N-glycan editing on living cell surfaces to probe glycoconjugate function

Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage

Structure-Based Discovery of a Subtype-Selective Inhibitor Targeting a Transient Receptor Potential Vanilloid Channel

Sulfonium, an Underestimated Moiety for Structural Modification, Alters the Antibacterial Profile of Vancomycin Against Multidrug-Resistant Bacteria

Synthesis and biological activity of metabolically stabilized cyclopentyl trisphosphate analogues of D-myo-Ins(1,4,5)P3.

Synthesis of Branched Peptides via a Side-Chain Benzyl Ester

Synthetic glycopeptides reveal the glycan specificity of HIV-neutralizing antibodies.

Thermostability detection and optimization of glycoengineered antibodies and antibody-drug conjugates based on differential scanning flouremitry analysis

Uncovering cryptic glycan markers in multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE).

Unusual transglycosylation activity of Flavobacterium meningosepticum endoglycosidases enables convergent chemoenzymatic synthesis of core fucosylated complex N-glycopeptides