Lista de obras - Christopher J. Hayes - Dominio Público Uruguay

A Method for Constructing the C18-C28 Dispiroacetal Moiety of Altohyrtin A.

artículo científico publicado en 1997

A convenient method for 3-pyrroline synthesis

scientific article published on 01 October 2001

A formal synthesis of (-)-cephalotaxine

scientific article published on 13 June 2008

A new one-Pot synthesis of alkynylphosphonates

artículo científico publicado en 2000

A second generation formal synthesis of (-)-cephalotaxine

artículo científico publicado en 2008

Accessing low-oxidation state taxanes: is taxadiene-4(5)-epoxide on the taxol biosynthetic pathway?

artículo científico publicado en 2016

Alkyl Halide-Free Heteroatom Alkylation and Epoxidation Facilitated by a Recyclable Polymer-Supported Oxidant for the In-Flow Preparation of Diazo Compounds

artículo científico publicado en 2015

An efficient enantioselective synthesis of (2R)-hydroxymethyl glutamic acid and an approach to the (2R)-hydroxymethyl-substituted sphingofungins

artículo científico publicado en 2006

An olefin cross-metathesis approach to vinylphosphonate-linked nucleic acids

artículo científico publicado en 2001

Asymmetric organocatalytic formation of protected and unprotected tetroses under potentially prebiotic conditions

artículo científico publicado en 2012

Bridgehead enolate or bridgehead organolithium? DFT calculations provide insights into a difficult bridgehead substitution reaction in the synthesis of the polycyclic polyprenylated acylphloroglucinol (PPAP) nemorosone

artículo científico publicado en 2013

Bridgehead lithiation-substitution of bridged ketones, lactones, lactams, and imides: experimental observations and computational insights

artículo científico publicado en 2009

C-H Insertion as a Key Step to Spiro-Oxetanes, Scaffolds for Drug Discovery

artículo científico publicado en 2017

CDK12 inhibition reduces abnormalities in cells from patients with myotonic dystrophy and in a mouse model

artículo científico publicado en 2020

Carbene reactivity of 4-diazo-4H-imidazoles toward nucleophiles and aromatic compounds

artículo científico publicado en 2009

Commercially available 5'-DMT phosphoramidites as reagents for the synthesis of vinylphosphonate-linked oligonucleic acids

scientific article published on 01 October 2001

Continuous-flow generation of diazoesters and their direct use in S–H and P–H insertion reactions: synthesis of α-sulfanyl, α-sulfonyl, and α-phosphono carboxylates

Effects of vinylphosphonate internucleotide linkages on the cleavage specificity of exonuclease III and on the activity of DNA polymerase I.

artículo científico publicado en 2003

Efficient asymmetric organocatalytic formation of erythrose and threose under aqueous conditions.

artículo científico publicado en 2010

Enantioselective synthesis of the excitatory amino acid (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid

artículo científico publicado en 2002

Enantioselective total syntheses of (-)-clasto-lactacystin beta-lactone and 7-epi-(-)-clasto-lactacystin beta-lactone

artículo científico publicado en 2005

Enantioselective total syntheses of omuralide, 7-epi-omuralide, and (+)-lactacystin

artículo científico publicado en 2008

High-content screening identifies small molecules that remove nuclear foci, affect MBNL distribution and CELF1 protein levels via a PKC-independent pathway in myotonic dystrophy cell lines

artículo científico publicado en 2013

Identification of internal ribosome entry segment (IRES)-trans-acting factors for the Myc family of IRESs

artículo científico publicado en 2007

Multigram synthesis of the C29-C51 subunit and completion of the total synthesis of altohyrtin C (spongistatin 2).

artículo científico publicado en 2003

Nucleophilic fluorination of β-ketoester derivatives with HBF4

artículo científico publicado en 2012

Phosphoramidate synthesis via copper-catalysed aerobic oxidative coupling of amines and H-phosphonates

artículo científico publicado en 2013

RPA alleviates the inhibitory effect of vinylphosphonate internucleotide linkages on DNA unwinding by BLM and WRN helicases

artículo científico publicado en 2004

Rapid access to α-alkoxy and α-amino acid derivatives through safe continuous-flow generation of diazoesters

artículo científico publicado en 2011

Redirection of carotenoid metabolism for the efficient production of taxadiene [taxa-4(5),11(12)-diene] in transgenic tomato fruit

artículo científico publicado en 2006

Rh(II)-catalysed room temperature aziridination of homoallyl-carbamates

scientific article published on 01 November 2006

Stereoselective Synthesis of Functionalized Pyrrolidines by the Diverted N-H Insertion Reaction of Metallocarbenes with β-Aminoketone Derivatives

artículo científico publicado en 2016

Stereoselective Synthesis of Highly Substituted Tetrahydrofurans through Diverted Carbene O-H Insertion Reaction

artículo científico publicado en 2015

Synthesis of the C1-C28 Portion of Spongistatin 1 (Altohyrtin A).

artículo científico publicado en 1999

Synthesis of the spirochroman core of dihypoestoxide and stereochemical proposal for the natural product

artículo científico publicado en 2010

Synthesis of triazole-linked morpholino oligonucleotides via Cu(I) catalysed cycloaddition

artículo científico publicado en 2016

Synthesis of β-keto esters in-flow and rapid access to substituted pyrimidines

artículo científico publicado en 2010

Synthetic studies towards the phomactins. Concise syntheses of the tricyclic furanochroman and the oxygenated bicyclo[9.3.1]pentadecane ring systems in phomactin A.

artículo científico publicado en 2003

The Impact of Macrocycle Conformation on the Taxadiene-Forming Carbocation Cascade: Insight Gained from Sobralene, a Recently Discovered Verticillene Isomer

artículo científico publicado en 2020

Total synthesis of (+)-cymbodiacetal: a re-evaluation of the biomimetic route

artículo científico publicado en 2010

Total synthesis of (-)-aritasone via the ultra-high pressure hetero-Diels-Alder dimerisation of (-)-pinocarvone.

artículo científico publicado en 2017

Translational reprogramming following UVB irradiation is mediated by DNA-PKcs and allows selective recruitment to the polysomes of mRNAs encoding DNA repair enzymes.

artículo científico publicado en 2009

Ultra-resolution imaging of a self-assembling biomolecular system using robust carbon nanotube AFM probes

artículo científico publicado en 2007

Vinylphosphonate internucleotide linkages inhibit the activity of PcrA DNA helicase.

artículo científico publicado en 2002

alpha,beta-Unsaturated and cyclopropyl acyl radicals, and their ketene alkyl radical equivalents. Ring synthesis and tandem cyclisation reactions

artículo científico publicado en 2004

Lista de obras de Christopher J. Hayes

A Method for Constructing the C18-C28 Dispiroacetal Moiety of Altohyrtin A.

A convenient method for 3-pyrroline synthesis

A formal synthesis of (-)-cephalotaxine

A new one-Pot synthesis of alkynylphosphonates

A second generation formal synthesis of (-)-cephalotaxine

Accessing low-oxidation state taxanes: is taxadiene-4(5)-epoxide on the taxol biosynthetic pathway?

Alkyl Halide-Free Heteroatom Alkylation and Epoxidation Facilitated by a Recyclable Polymer-Supported Oxidant for the In-Flow Preparation of Diazo Compounds

An efficient enantioselective synthesis of (2R)-hydroxymethyl glutamic acid and an approach to the (2R)-hydroxymethyl-substituted sphingofungins

An olefin cross-metathesis approach to vinylphosphonate-linked nucleic acids

Asymmetric organocatalytic formation of protected and unprotected tetroses under potentially prebiotic conditions

Bridgehead enolate or bridgehead organolithium? DFT calculations provide insights into a difficult bridgehead substitution reaction in the synthesis of the polycyclic polyprenylated acylphloroglucinol (PPAP) nemorosone

Bridgehead lithiation-substitution of bridged ketones, lactones, lactams, and imides: experimental observations and computational insights

C-H Insertion as a Key Step to Spiro-Oxetanes, Scaffolds for Drug Discovery

CDK12 inhibition reduces abnormalities in cells from patients with myotonic dystrophy and in a mouse model

Carbene reactivity of 4-diazo-4H-imidazoles toward nucleophiles and aromatic compounds

Commercially available 5'-DMT phosphoramidites as reagents for the synthesis of vinylphosphonate-linked oligonucleic acids

Continuous-flow generation of diazoesters and their direct use in S–H and P–H insertion reactions: synthesis of α-sulfanyl, α-sulfonyl, and α-phosphono carboxylates

Effects of vinylphosphonate internucleotide linkages on the cleavage specificity of exonuclease III and on the activity of DNA polymerase I.

Efficient asymmetric organocatalytic formation of erythrose and threose under aqueous conditions.

Enantioselective synthesis of the excitatory amino acid (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid

Enantioselective total syntheses of (-)-clasto-lactacystin beta-lactone and 7-epi-(-)-clasto-lactacystin beta-lactone

Enantioselective total syntheses of omuralide, 7-epi-omuralide, and (+)-lactacystin

High-content screening identifies small molecules that remove nuclear foci, affect MBNL distribution and CELF1 protein levels via a PKC-independent pathway in myotonic dystrophy cell lines

Identification of internal ribosome entry segment (IRES)-trans-acting factors for the Myc family of IRESs

Multigram synthesis of the C29-C51 subunit and completion of the total synthesis of altohyrtin C (spongistatin 2).

Nucleophilic fluorination of β-ketoester derivatives with HBF4

Phosphoramidate synthesis via copper-catalysed aerobic oxidative coupling of amines and H-phosphonates

RPA alleviates the inhibitory effect of vinylphosphonate internucleotide linkages on DNA unwinding by BLM and WRN helicases

Rapid access to α-alkoxy and α-amino acid derivatives through safe continuous-flow generation of diazoesters

Redirection of carotenoid metabolism for the efficient production of taxadiene [taxa-4(5),11(12)-diene] in transgenic tomato fruit

Rh(II)-catalysed room temperature aziridination of homoallyl-carbamates

Stereoselective Synthesis of Functionalized Pyrrolidines by the Diverted N-H Insertion Reaction of Metallocarbenes with β-Aminoketone Derivatives

Stereoselective Synthesis of Highly Substituted Tetrahydrofurans through Diverted Carbene O-H Insertion Reaction

Synthesis of the C1-C28 Portion of Spongistatin 1 (Altohyrtin A).

Synthesis of the spirochroman core of dihypoestoxide and stereochemical proposal for the natural product

Synthesis of triazole-linked morpholino oligonucleotides via Cu(I) catalysed cycloaddition

Synthesis of β-keto esters in-flow and rapid access to substituted pyrimidines

Synthetic studies towards the phomactins. Concise syntheses of the tricyclic furanochroman and the oxygenated bicyclo[9.3.1]pentadecane ring systems in phomactin A.

The Impact of Macrocycle Conformation on the Taxadiene-Forming Carbocation Cascade: Insight Gained from Sobralene, a Recently Discovered Verticillene Isomer

Total synthesis of (+)-cymbodiacetal: a re-evaluation of the biomimetic route

Total synthesis of (-)-aritasone via the ultra-high pressure hetero-Diels-Alder dimerisation of (-)-pinocarvone.

Translational reprogramming following UVB irradiation is mediated by DNA-PKcs and allows selective recruitment to the polysomes of mRNAs encoding DNA repair enzymes.

Ultra-resolution imaging of a self-assembling biomolecular system using robust carbon nanotube AFM probes

Vinylphosphonate internucleotide linkages inhibit the activity of PcrA DNA helicase.

alpha,beta-Unsaturated and cyclopropyl acyl radicals, and their ketene alkyl radical equivalents. Ring synthesis and tandem cyclisation reactions