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Lista de obras de Luc Pellerin

A coherent neurobiological framework for functional neuroimaging provided by a model integrating compartmentalized energy metabolism

artículo científico publicado en 2007

A neuronal MCT2 knockdown in the rat somatosensory cortex reduces both the NMR lactate signal and the BOLD response during whisker stimulation

artículo científico publicado en 2017

A novel method for in vitro production of human glial-like cells from neurosurgical resection tissue

artículo científico publicado en 2002

A probable dual mode of action for both L- and D-lactate neuroprotection in cerebral ischemia

artículo científico publicado en 2015

A protein assay program for Lotus 1-2-3.

artículo científico publicado en 1990

A2B receptor activation promotes glycogen synthesis in astrocytes through modulation of gene expression

artículo científico publicado en 2002

AMPK activation caused by reduced liver lactate metabolism protects against hepatic steatosis in MCT1 haploinsufficient mice.

artículo científico publicado en 2017

Activation of astrocytes by CNTF induces metabolic plasticity and increases resistance to metabolic insults.

artículo científico publicado en 2007

Activity-dependent regulation of energy metabolism by astrocytes: an update

artículo científico publicado en 2007

Adenosine triphosphate and arachidonic acid stimulate glycogenolysis in primary cultures of mouse cerebral cortical astrocytes

article

Alteration of glucose metabolism in cultured astrocytes after AQP9-small interference RNA application

artículo científico publicado en 2012

Altered mRNA and Protein Expression of Monocarboxylate Transporter MCT1 in the Cerebral Cortex and Cerebellum of Prion Protein Knockout Mice

artículo científico publicado en 2021

Alzheimer's disease: the amyloid hypothesis and the Inverse Warburg effect

artículo científico publicado en 2014

Ampakine CX546 bolsters energetic response of astrocytes: a novel target for cognitive-enhancing drugs acting as alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor modulators

artículo científico publicado en 2005

Arachidonic acid augments potassium currents in rat neocortical neurones.

artículo científico publicado en 1993

Arachidonic acid metabolites in the rat and human brain. New findings on the metabolism of prostaglandin D2 and lipoxygenase products

artículo científico publicado en 1989

Astrocytes Couple Synaptic Activity to Glucose Utilization in the Brain

artículo científico publicado en 1999

Astrocytes are key but indirect contributors to the development of the symptomatology and pathophysiology of Huntington's disease

artículo científico publicado en 2016

Astrocytes as a predominant cellular site of (99m)Tc-HMPAO retention

artículo científico publicado en 2001

Basal and stimulated lactate fluxes in primary cultures of astrocytes are differentially controlled by distinct proteins

artículo científico publicado en 2008

Brain energetics (thought needs food).

artículo científico publicado en 2008

Brain energy consumption induced by electrical stimulation promotes systemic glucose uptake

artículo científico publicado en 2011

Brain energy metabolism in Alzheimer’s disease: 99mTc-HMPAO SPECT imaging during verbal fluency and role of astrocytes in the cellular mechanism of 99mTc-HMPAO retention

artículo científico publicado en 2001

Brain hepoxilins: formation and action

artículo científico publicado en 1989

Brain lactate kinetics: Modeling evidence for neuronal lactate uptake upon activation

artículo científico publicado en 2005

Brain-derived neurotrophic factor enhances the expression of the monocarboxylate transporter 2 through translational activation in mouse cultured cortical neurons.

artículo científico publicado en 2009

Brain-derived neurotrophic factor enhances the hippocampal expression of key postsynaptic proteins in vivo including the monocarboxylate transporter MCT2.

artículo científico publicado en 2011

Caveolin expression changes in the neurovascular unit after juvenile traumatic brain injury: signs of blood-brain barrier healing?

artículo científico publicado en 2014

Cell-specific expression pattern of monocarboxylate transporters in astrocytes and neurons observed in different mouse brain cortical cell cultures

artículo científico publicado en 2003

Cell-specific localization of monocarboxylate transporters, MCT1 and MCT2, in the adult mouse brain revealed by double immunohistochemical labeling and confocal microscopy

artículo científico publicado en 2000

Cell-specific modulation of monocarboxylate transporter expression contributes to the metabolic reprograming taking place following cerebral ischemia

artículo científico publicado en 2016

Cellular and subcellular distribution of monocarboxylate transporters in cultured brain cells and in the adult brain.

artículo científico publicado en 2005

Cellular bases of brain energy metabolism and their relevance to functional brain imaging: evidence for a prominent role of astrocytes.

artículo científico publicado en 1996

Cellular distribution of glucose and monocarboxylate transporters in human brain white matter and multiple sclerosis lesions

artículo científico publicado en 2014

Cellular mechanisms of brain energy metabolism and their relevance to functional brain imaging.

artículo científico publicado en 1999

Cellular mechanisms of brain energy metabolism. Relevance to functional brain imaging and to neurodegenerative disorders

artículo científico publicado en 1996

Cerebral Ketone Body Oxidation Is Facilitated by a High Fat Diet Enriched with Advanced Glycation End Products in Normal and Diabetic Rats.

artículo científico publicado en 2016

Comment on recent modeling studies of astrocyte-neuron metabolic interactions

artículo científico publicado en 2010

Comparison of lactate transport in astroglial cells and monocarboxylate transporter 1 (MCT 1) expressing Xenopus laevis oocytes. Expression of two different monocarboxylate transporters in astroglial cells and neurons

artículo científico publicado en 1997

Competition between glucose and lactate as oxidative energy substrates in both neurons and astrocytes: a comparative NMR study

artículo científico publicado en 2006

Cortical Bilateral Adaptations in Rats Submitted to Focal Cerebral Ischemia: Emphasis on Glial Metabolism.

artículo científico publicado en 2017

Cryopreservation of human brain tissue allowing timely production of viable adult human brain cells for autologous transplantation

artículo científico publicado en 2003

Current technical approaches to brain energy metabolism

artículo científico publicado en 2017

Deep hypothermia and rewarming alters glutamate levels and glycogen content in cultured astrocytes

artículo científico publicado en 1999

Deficiency in monocarboxylate transporter 1 (MCT1) in mice delays regeneration of peripheral nerves following sciatic nerve crush.

artículo científico publicado en 2014

Determinants of brain cell metabolic phenotypes and energy substrate utilization unraveled with a modeling approach

artículo científico publicado en 2012

Developmental and hormonal regulation of the monocarboxylate transporter 2 (MCT2) expression in the mouse germ cells

artículo científico publicado en 2003

Differential messenger RNA distribution of lactate dehydrogenase LDH-1 and LDH-5 isoforms in the rat brain

artículo científico publicado en 2000

Distribution of monocarboxylate transporters in the peripheral nervous system suggests putative roles in lactate shuttling and myelination.

artículo científico publicado en 2015

Distribution of the monocarboxylate transporter MCT2 in human cerebral cortex: an immunohistochemical study

artículo científico publicado en 2008

Dual-gene, dual-cell type therapy against an excitotoxic insult by bolstering neuroenergetics.

artículo científico publicado en 2004

E4F1-mediated control of pyruvate dehydrogenase activity is essential for skin homeostasis.

artículo científico publicado en 2016

Early acquisition of typical metabolic features upon differentiation of mouse neural stem cells into astrocytes

artículo científico publicado en 2004

Effects of sodium arsenite on neurite outgrowth and glutamate AMPA receptor expression in mouse cortical neurons

artículo científico publicado en 2013

Empiricism and rationalism: two paths toward the same goal

artículo científico publicado en 2004

Endothelial cell-derived nitric oxide enhances aerobic glycolysis in astrocytes via HIF-1α-mediated target gene activation

artículo científico publicado en 2012

Energy on demand

artículo científico publicado en 1999

Enhanced expression of three monocarboxylate transporter isoforms in the brain of obese mice.

artículo científico publicado en 2007

Evidence for hypothalamic ketone body sensing: impact on food intake and peripheral metabolic responses in mice.

artículo científico publicado en 2015

Evidence supporting the existence of an activity-dependent astrocyte-neuron lactate shuttle

artículo científico publicado en 1998

Excitatory amino acids stimulate aerobic glycolysis in astrocytes via an activation of the Na+/K+ ATPase

artículo científico publicado en 1996

Expression of monocarboxylate transporter mRNAs in mouse brain: support for a distinct role of lactate as an energy substrate for the neonatal vs. adult brain

artículo científico publicado en 1998

Expression of the monocarboxylate transporter MCT1 in the adult human brain cortex

artículo científico publicado en 2006

Feeding active neurons: (re)emergence of a nursing role for astrocytes

artículo científico publicado en 2002

Focal cerebral ischaemia induces a decrease in activity and a shift in ouabain affinity of Na+, K+-ATPase isoforms without modifications in mRNA and protein expression

artículo científico publicado en 1999

Food for thought: the importance of glucose and other energy substrates for sustaining brain function under varying levels of activity ⬇️

artículo científico publicado el 1 de octubre de 2010

GABA uptake into astrocytes is not associated with significant metabolic cost: Implications for brain imaging of inhibitory transmission ⬇️

artículo científico publicado el 6 de octubre de 2003

Glial glutamate transporters mediate a functional metabolic crosstalk between neurons and astrocytes in the mouse developing cortex

artículo científico publicado en 2003

Glucocorticoids modulate neurotransmitter-induced glycogen metabolism in cultured cortical astrocytes.

artículo científico publicado en 2004

Glutamate reduces glucose utilization while concomitantly enhancing AQP9 and MCT2 expression in cultured rat hippocampal neurons

artículo científico publicado en 2014

Glutamate uptake stimulates Na+,K+-ATPase activity in astrocytes via activation of a distinct subunit highly sensitive to ouabain.

artículo científico publicado en 1997

Glycogen metabolism as a marker of astrocyte differentiation

artículo científico publicado en 2009

How astrocytes feed hungry neurons.

artículo científico publicado en 2005

How to balance the brain energy budget while spending glucose differently

artículo científico publicado en 2003

Hyperpalatable Diet and Physical Exercise Modulate the Expression of the Glial Monocarboxylate Transporters MCT1 and 4.

artículo científico publicado en 2016

Hypothalamic sensing of ketone bodies after prolonged cerebral exposure leads to metabolic control dysregulation.

artículo científico publicado en 2016

Immunocytochemical expression of monocarboxylate transporters in the human visual cortex at midgestation

artículo científico publicado en 2004

Impact of MCT1 Haploinsufficiency on the Mouse Retina.

artículo científico publicado en 2018

Improvement of Neuroenergetics by Hypertonic Lactate Therapy in Patients with Traumatic Brain Injury Is Dependent on Baseline Cerebral Lactate/Pyruvate Ratio

artículo científico publicado en 2015

Increased expression of monocarboxylate transporters 1, 2, and 4 in colorectal carcinomas.

artículo científico publicado en 2008

Insights into neuronal cell metabolism using NMR spectroscopy: uridyl diphosphate N-acetyl-glucosamine as a unique metabolic marker.

artículo científico publicado en 2011

Insulin and IGF-1 enhance the expression of the neuronal monocarboxylate transporter MCT2 by translational activation via stimulation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin pathway

artículo científico publicado en 2007

Lactate as a pivotal element in neuron-glia metabolic cooperation.

artículo científico publicado en 2003

Lactate is a preferential oxidative energy substrate over glucose for neurons in culture

artículo científico publicado en 2003

Linking supply to demand: the neuronal monocarboxylate transporter MCT2 and the alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionic acid receptor GluR2/3 subunit are associated in a common trafficking process.

artículo científico publicado en 2009

Local injection of antisense oligonucleotides targeted to the glial glutamate transporter GLAST decreases the metabolic response to somatosensory activation.

artículo científico publicado en 2001

Long-Lasting Metabolic Imbalance Related to Obesity Alters Olfactory Tissue Homeostasis and Impairs Olfactory-Driven Behaviors.

artículo científico publicado en 2015

Long-term changes of synaptic transmission induced by arachidonic acid in the CA1 subfield of the rat hippocampus

artículo científico publicado en 1990

Long-term modulation of glucose utilization by IL-1 alpha and TNF-alpha in astrocytes: Na+ pump activity as a potential target via distinct signaling mechanisms

artículo científico publicado en 2002

Low plasma lactate concentration as a biomarker of an incompetent brain-pull: a risk factor for weight gain in type 2 diabetes patients

artículo científico publicado en 2010

MCT2 is a major neuronal monocarboxylate transporter in the adult mouse brain

artículo científico publicado en 2002

Making sense of AMPA receptor trafficking by modeling molecular mechanisms of synaptic plasticity

artículo científico publicado en 2008

Metabolic activation pattern of distinct hippocampal subregions during spatial learning and memory retrieval

artículo científico publicado en 2006

Metabolic compartmentalization in the human cortex and hippocampus: evidence for a cell- and region-specific localization of lactate dehydrogenase 5 and pyruvate dehydrogenase

artículo científico publicado en 2007

Metabolic coupling during activation. A cellular view

artículo científico publicado en 1997

Metabolism of prostaglandin D2 by human cerebral cortex into 9 alpha, 11 beta-prostaglandin F2 by an active NADPH-dependent 11-ketoreductase

artículo científico publicado en 1989

Modulation of the glutamate-evoked release of arachidonic acid from mouse cortical neurons: involvement of a pH-sensitive membrane phospholipase A2

artículo científico publicado en 1995

Monocarboxylate transporters in the brain and in cancer.

artículo científico publicado en 2016

Monocarboxylate transporters in the central nervous system: distribution, regulation and function.

artículo científico publicado en 2005

Monocarboxylate transporters: new players in body weight regulation.

artículo científico publicado en 2015

NEUROSCIENCE: Let There Be (NADH) Light

artículo científico publicado en 2004

Neuroenergetic Response to Prolonged Cerebral Glucose Depletion after Severe Brain Injury and the Role of Lactate

artículo científico publicado en 2015

Neuroenergetic response to prolonged cerebral glucose depletion after severe brain injury and the role of lactate

artículo científico publicado en 2015

Neuroenergetics: Astrocytes Have a Sweet Spot for Glucose

artículo científico publicado en 2018

Neuroenergetics: calling upon astrocytes to satisfy hungry neurons

artículo científico publicado en 2004

Neuroprotective effect of rLosac on supplement-deprived mouse cultured cortical neurons involves maintainance of monocarboxylate transporter MCT2 protein levels

article

Neurotransmitters regulate energy metabolism in astrocytes: implications for the metabolic trafficking between neural cells.

artículo científico publicado en 1993

Nitric oxide induces the expression of the monocarboxylate transporter MCT4 in cultured astrocytes by a cGMP-independent transcriptional activation

artículo científico publicado en 2011

Noradrenaline enhances monocarboxylate transporter 2 expression in cultured mouse cortical neurons via a translational regulation

artículo científico publicado en 2003

Noradrenaline enhances the expression of the neuronal monocarboxylate transporter MCT2 by translational activation via stimulation of PI3K/Akt and the mTOR/S6K pathway

artículo científico publicado en 2007

Oligodendroglia metabolically support axons and contribute to neurodegeneration.

artículo científico publicado en 2012

Oxygen tension controls the expression of the monocarboxylate transporter MCT4 in cultured mouse cortical astrocytes via a hypoxia-inducible factor-1α-mediated transcriptional regulation.

artículo científico publicado en 2013

Perinatal and early postnatal changes in the expression of monocarboxylate transporters MCT1 and MCT2 in the rat forebrain

artículo científico publicado en 2003

Protein targeting to glycogen mRNA expression is stimulated by noradrenaline in mouse cortical astrocytes

scientific article published on 01 June 2000

Quantitative rt-PCR analysis of uncoupling protein isoforms in mouse brain cortex: methodological optimization and comparison of expression with brown adipose tissue and skeletal muscle

artículo científico publicado en 2004

Regulation by neurotransmitters of glial energy metabolism.

artículo científico publicado en 1997

Regulation of Astrocyte Energy Metabolism by Neurotransmitters

scientific article published on 01 May 1994

Regulation of the intracellular distribution, cell surface expression, and protein levels of AMPA receptor GluR2 subunits by the monocarboxylate transporter MCT2 in neuronal cells.

artículo científico publicado en 2009

Release of arachidonic acid by NMDA-receptor activation in the rat hippocampus

artículo científico publicado en 1991

Resistance to diet-induced obesity and associated metabolic perturbations in haploinsufficient monocarboxylate transporter 1 mice

scientific journal article

Rise in plasma lactate concentrations with psychosocial stress: a possible sign of cerebral energy demand

artículo científico publicado en 2012

Role of MCT1 and CAII in skeletal muscle pH homeostasis, energetics, and function: in vivo insights from MCT1 haploinsufficient mice

artículo científico publicado en 2017

Role of neuron-glia interaction in the regulation of brain glucose utilization.

artículo científico publicado en 2002

Selective distribution of lactate dehydrogenase isoenzymes in neurons and astrocytes of human brain

artículo científico publicado en 1996

Selective postsynaptic co-localization of MCT2 with AMPA receptor GluR2/3 subunits at excitatory synapses exhibiting AMPA receptor trafficking

artículo científico publicado en 2005

Similar perisynaptic glial localization for the Na+,K+-ATPase alpha 2 subunit and the glutamate transporters GLAST and GLT-1 in the rat somatosensory cortex

scientific journal article

Stimulation-induced increases of astrocytic oxidative metabolism in rats and humans investigated with 1-11C-acetate

artículo científico publicado en 2008

Sweet Sixteen for ANLS ⬇️

artículo científico publicado el 26 de octubre de 2011

Synthesis and functions of cyclooxygenase and lipoxygenase products in brain: new findings and an appraisal

artículo científico publicado en 1989

Temporal changes in mRNA expression of the brain nutrient transporters in the lithium-pilocarpine model of epilepsy in the immature and adult rat.

artículo científico publicado en 2011

The Hepatic Monocarboxylate Transporter 1 (MCT1) Contributes to the Regulation of Food Anticipation in Mice

artículo científico publicado en 2021

The Self-Inactivating KamiCas9 System for the Editing of CNS Disease Genes

artículo científico publicado en 2017

The anorexigenic effects of metformin involve increases in hypothalamic leptin receptor expression

artículo científico publicado en 2010

The astrocyte-mediated coupling between synaptic activity and energy metabolism operates through volume transmission.

artículo científico publicado en 2000

Trans-inhibition of glutamate transport prevents excitatory amino acid-induced glycolysis in astrocytes

scientific article published on 01 December 1999

Transfer of glycogen-derived lactate from astrocytes to axons via specific monocarboxylate transporters supports mouse optic nerve activity.

artículo científico publicado en 2005

Unraveling the complex metabolic nature of astrocytes

artículo científico publicado en 2013

Unusual astrocyte reactivity caused by the food mycotoxin ochratoxin A in aggregating rat brain cell cultures

artículo científico publicado en 2005

What you see is what you think--or is it?

artículo científico publicado en 2001

[18F]FDG PET signal is driven by astroglial glutamate transport

artículo científico publicado en 2017

[Functional brain imaging: role metabolic coupling between astrocytes and neurons]

artículo científico publicado en 2000

[Is lactate a major energy substrate for neurons?]

artículo científico publicado en 2006

beta-Adrenergic stimulation promotes homocysteic acid release from astrocyte cultures: evidence for a role of astrocytes in the modulation of synaptic transmission.

artículo científico publicado en 1997

β-Hydroxybutyrate supports synaptic vesicle cycling but reduces endocytosis and exocytosis in rat brain synaptosomes.

artículo científico publicado en 2015

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