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Lista de obras de Phillip J. Robinson

1,8-Naphthalimide derivatives: new leads against dynamin I GTPase activity

artículo científico publicado en 2015

5-Aryl-2-(naphtha-1-yl)sulfonamido-thiazol-4(5H)-ones as clathrin inhibitors

artículo científico publicado en 2016

A Cholesterol-Dependent Endocytic Mechanism Generates Midbody Tubules During Cytokinesis

artículo científico publicado en 2015

A Direct Fluorescent Activity Assay for Glycosyltransferases Enables Convenient High-Throughput Screening: Application to O-GlcNAc Transferase

artículo científico publicado en 2020

A Novel Post-translational Modification in Nerve Terminals: O-LinkedN-Acetylglucosamine Phosphorylation

artículo científico publicado en 2011

A Novel Sequence in AP180 and CALM Promotes Efficient Clathrin Binding and Assembly

artículo científico publicado en 2016

A comparative study of the role of adenylate cyclase in the release of adrenocorticotropin from the ovine and rat anterior pituitary

artículo científico publicado en 1994

A rapid Percoll gradient procedure for preparation of synaptosomes

artículo científico publicado en 2008

A synthetic peptide analog of the putative substrate-binding motif activates protein kinase C

artículo científico publicado en 1989

Actin- and dynamin-dependent maturation of bulk endocytosis restores neurotransmission following synaptic depletion

artículo científico publicado en 2012

Activation of protein kinase C in vitro and in intact cells or synaptosomes determined by acetic acid extraction of MARCKS.

artículo científico publicado en 1993

Adrenocorticotropin causes vasodilatation in the human fetal-placental circulation

artículo científico publicado en 1996

Altered protein phosphorylation in intact rat cortical synaptosomes after in vivo administration of fluphenazine

artículo científico publicado en 1987

An integrated flow and microwave approach to a broad spectrum protein kinase inhibitor

scholarly article in RSC Advances, vol. 5 no. 113, 2015

Analysis of synaptic vesicle endocytosis in synaptosomes by high-content screening.

artículo científico publicado en 2012

Arginine vasopressin (AVP) causes the reversible phosphorylation of the myristoylated alanine-rich C kinase substrate (MARCKS) protein in the ovine anterior pituitary: evidence that MARCKS phosphorylation is associated with adrenocorticotropin (ACTH

artículo científico publicado en 1994

Arginine vasopressin (AVP) causes the reversible phosphorylation of the myristoylated alanine-rich C kinase substrate (MARCKS) protein in the ovine anterior pituitary: evidence that MARCKS phosphorylation is associated with adrenocorticotropin (ACTH)

article

Autophosphorylation and ATM activation: additional sites add to the complexity

artículo científico publicado en 2010

Azido and diazarinyl analogues of bis-tyrphostin as asymmetrical inhibitors of dynamin GTPase

artículo científico publicado en 2009

Ba2+ does not support synaptic vesicle retrieval in rat cerebrocortical synaptosomes.

artículo científico publicado en 1998

Barocycler-Based Concurrent Multiomics Method To Assess Molecular Changes Associated with Atherosclerosis Using Small Amounts of Arterial Tissue from a Single Mouse

artículo científico publicado en 2019

Basal and KCl-stimulated corticotropin-releasing hormone release from human placental syncytiotrophoblasts is inhibited by sodium nitroprusside

artículo científico publicado en 1994

Building a better dynasore: the dyngo compounds potently inhibit dynamin and endocytosis

artículo científico publicado en 2013

Calcineurin activity is required for the completion of cytokinesis

artículo científico publicado en 2010

Calcineurin selectively docks with the dynamin Ixb splice variant to regulate activity-dependent bulk endocytosis

artículo científico

Calcium channel agonists and antagonists regulate protein phosphorylation in intact synaptosomes

artículo científico publicado en 1986

Calcium-stimulated protein kinases from rat cerebral cortex are inactivated by preincubation

artículo científico publicado en 1981

Cdk1/Erk2- and Plk1-dependent phosphorylation of a centrosome protein, Cep55, is required for its recruitment to midbody and cytokinesis.

artículo científico publicado en 2005

Cdk5 is essential for synaptic vesicle endocytosis

scientific journal article

Chapter 12 Phosphoproteomics

Chapter 22 Depolarization-dependent protein phosphorylation in synaptosomes: mechanisms and significance

Characterization of the urinary albumin degradation pathway in the isolated perfused rat kidney

artículo científico publicado en 2006

Chloride channel ClC-5 binds to aspartyl aminopeptidase to regulate renal albumin endocytosis

scientific article published on 13 January 2015

Cholinoceptor regulation of cyclic AMP levels in bovine adrenal medullary cells

artículo científico publicado en 1992

Clathrin terminal domain-ligand interactions regulate sorting of mannose 6-phosphate receptors mediated by AP-1 and GGA adaptors

scientific article published on 09 January 2014

Clathrin-independent carriers form a high capacity endocytic sorting system at the leading edge of migrating cells

artículo científico publicado en 2010

Corticotropin-releasing hormone-induced vasodilatation in the human fetal placental circulation.

artículo científico publicado en 1994

Decreased phorbol ester binding in the parahippocampal gyrus from subjects with schizophrenia is not associated with changes in protein kinase C.

artículo científico publicado en 2002

Dephosphin, a 96,000 Da substrate of protein kinase C in synaptosomal cytosol, is phosphorylated in intact synaptosomes

artículo científico publicado en 1991

Dephosphin/dynamin is a neuronal phosphoprotein concentrated in nerve terminals: Evidence from rat cerebellum

article

Depolarization-dependent protein phosphorylation in rat cortical synaptosomes: the effects of calcium, strontium and barium

artículo científico publicado en 1983

Development of 1,8-naphthalimides as clathrin inhibitors

artículo científico publicado en 2013

Development of quinone analogues as dynamin GTPase inhibitors

artículo científico publicado en 2014

Development of second-generation indole-based dynamin GTPase inhibitors

artículo científico publicado en 2012

Differential phosphorylation of dynamin I isoforms in subcellular compartments demonstrates the hidden complexity of phosphoproteomes

artículo científico publicado en 2010

Dimerization of CtIP, a BRCA1- and CtBP-interacting protein, is mediated by an N-terminal coiled-coil motif

artículo científico publicado en 2004

Dopamine and serotonin in two populations of synaptosomes isolated by percoll gradient centrifugation

artículo científico publicado en 1986

Dynamin 2 is essential for mammalian spermatogenesis.

artículo científico publicado en 2016

Dynamin GTPase regulated by protein kinase C phosphorylation in nerve terminals

artículo científico publicado en 1993

Dynamin I phosphorylation by GSK3 controls activity-dependent bulk endocytosis of synaptic vesicles.

artículo científico publicado en 2010

Dynamin II function is required for EGF-mediated Stat3 activation but not Erk1/2 phosphorylation.

artículo científico publicado en 2012

Dynamin inhibition blocks botulinum neurotoxin type A endocytosis in neurons and delays botulism

artículo científico publicado en 2011

Dynamin inhibitors induce caspase-mediated apoptosis following cytokinesis failure in human cancer cells and this is blocked by Bcl-2 overexpression

artículo científico publicado en 2011

Dynamin inhibits phosphatidylinositol 3-kinase in hematopoietic cells.

artículo científico publicado en 2001

Dynamin regulates specific membrane fusion events necessary for acrosomal exocytosis in mouse spermatozoa.

artículo científico publicado en 2012

Enhanced Protein Recovery and Reproducibility from Pull-Down Assays and Immunoprecipitations Using Spin Columns

artículo científico publicado en 2001

Evidence that the stimulation by arginine vasopressin of the release of adrenocorticotropin from the ovine anterior pituitary involves the activation of protein kinase C.

artículo científico publicado en 1992

Expanding the clinical, pathological and MRI phenotype of DNM2-related centronuclear myopathy

artículo científico publicado en 2010

FD5180, a Novel Protein Kinase Affinity Probe, and the Effect of Bead Loading on Protein Kinase Identification

From Spanish fly to room-temperature ionic liquids (RTILs): synthesis, thermal stability and inhibition of dynamin 1 GTPase by a novel class of RTILs

article

Genotoxic stress-induced nuclear localization of oncoprotein YB-1 in the absence of proteolytic processing.

artículo científico publicado en 2009

Glycogen synthase kinase 3 regulates acrosomal exocytosis in mouse spermatozoa via dynamin phosphorylation.

artículo científico publicado en 2015

HIV infection is influenced by dynamin at 3 independent points in the viral life cycle.

artículo científico publicado en 2017

Hypertrophy and dietary tyrosine ameliorate the phenotypes of a mouse model of severe nemaline myopathy

article

IQGAP1 is associated with nuclear envelope reformation and completion of abscission

artículo científico publicado en 2015

Identification and characterisation of the RalA-ERp57 interaction: evidence for GDI activity of ERp57.

artículo científico publicado en 2012

Identification of TPIT and other novel autoantigens in lymphocytic hypophysitis: immunoscreening of a pituitary cDNA library and development of immunoprecipitation assays

artículo científico publicado en 2011

Identification of a family of DNA-binding proteins with homology to RNA splicing factors

artículo científico publicado en 2006

Identification of cGMP-dependent protein kinase and its specific substrates in the anterior pituitary

artículo científico publicado en 1996

Identification of the 49-kDa autoantigen associated with lymphocytic hypophysitis as alpha-enolase

artículo científico publicado en 2002

Iminochromene inhibitors of dynamins I and II GTPase activity and endocytosis

artículo científico publicado en 2010

Improved detection of hydrophilic phosphopeptides using graphite powder microcolumns and mass spectrometry: evidence for in vivo doubly phosphorylated dynamin I and dynamin III.

artículo científico publicado en 2004

Increased levels of SNAP-25 and synaptophysin in the dorsolateral prefrontal cortex in bipolar I disorder

artículo científico publicado en 2006

Inhibition of clathrin by pitstop 2 activates the spindle assembly checkpoint and induces cell death in dividing HeLa cancer cells

artículo científico publicado en 2013

Inhibition of dynamin by dynole 34-2 induces cell death following cytokinesis failure in cancer cells

artículo científico publicado en 2011

Inhibition of dynamin mediated endocytosis by the dynoles--synthesis and functional activity of a family of indoles

artículo científico publicado en 2009

Intranuclear rod myopathy: molecular pathogenesis and mechanisms of weakness

artículo científico publicado en 2007

Involvement of novel autophosphorylation sites in ATM activation

artículo científico publicado en 2006

Kruppel-associated Box (KRAB)-associated co-repressor (KAP-1) Ser-473 phosphorylation regulates heterochromatin protein 1β (HP1-β) mobilization and DNA repair in heterochromatin

artículo científico publicado en 2012

Label-free quantitation of phosphopeptide changes during rat sperm capacitation.

artículo científico publicado en 2010

Long chain amines and long chain ammonium salts as novel inhibitors of dynamin GTPase activity

artículo científico publicado en 2004

Loss of Dynamin 2 GTPase function results in microcytic anaemia

artículo científico publicado en 2017

Loss-of-function mutations of Dynamin 2 promote T-ALL by enhancing IL-7 signalling.

artículo científico publicado en 2016

Mammalian septins nomenclature

artículo científico publicado en 2002

Mechanisms of calcineurin inhibitor-induced neurotoxicity

Mechanisms of synaptic vesicle recycling illuminated by fluorescent dyes.

artículo científico publicado en 1999

Membrane fission by dynamin: what we know and what we need to know

artículo científico publicado en 2016

Microtubule-associated protein 6 mediates neuronal connectivity through Semaphorin 3E-dependent signalling for axonal growth.

artículo científico publicado en 2015

Multisite phosphorylation of doublecortin by cyclin-dependent kinase 5.

artículo científico publicado en 2004

Mutations in the SPTLC1 Protein Cause Mitochondrial Structural Abnormalities and Endoplasmic Reticulum Stress in Lymphoblasts

scholarly article by Simon J. Myers published in July 2014

Myristyl Trimethyl Ammonium Bromide and Octadecyl Trimethyl Ammonium Bromide Are Surface-Active Small Molecule Dynamin Inhibitors that Block Endocytosis Mediated by Dynamin I or Dynamin II

artículo científico publicado en 2007

NEUROSCIENCE: How to Fill a Synapse

artículo científico publicado en 2007

Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief

artículo científico publicado en 2017

Optimization of calmodulin-affinity chromatography for brain and organelles

PICK1 interacts with PACSIN to regulate AMPA receptor internalization and cerebellar long-term depression

scientific article published on 05 August 2013

Parallel Solution-Phase Synthesis of Targeted Tyrphostin Libraries with Anticancer Activity

Pharmacological inhibition of dynamin II reduces constitutive protein secretion from primary human macrophages

artículo científico publicado en 2014

Phenothiazine-derived antipsychotic drugs inhibit dynamin and clathrin-mediated endocytosis

artículo científico publicado en 2015

Phosphorylation of dynamin II at serine-764 is associated with cytokinesis

artículo científico publicado en 2010

Phosphorylation of phospholamban in aortic smooth muscle cells and heart by calcium/calmodulin-dependent protein kinase II.

artículo científico

Phosphorylation of proteins in chick ciliary ganglion under conditions that induce long-lasting changes in synaptic transmission: phosphoprotein targets for nitric oxide action.

artículo científico publicado en 1999

Phosphorylation of septin 3 on Ser-91 by cGMP-dependent protein kinase-I in nerve terminals

artículo científico publicado en 2004

Phosphorylation of synaptosomal cytoplasmic proteins: Inhibition of calcium-activated, phospholipid-dependent protein kinase (protein kinase c) by bay k 8644.

artículo científico publicado en 1988

Phosphorylation of syndapin I F-BAR domain at two helix-capping motifs regulates membrane tubulation

scientific journal article

Phosphorylation regulates copper-responsive trafficking of the Menkes copper transporting P-type ATPase.

artículo científico publicado en 2009

Pituitary autoantibodies

Potencies of protein kinase C inhibitors are dependent on the activators used to stimulate the enzyme

artículo científico publicado el 6 de octubre de 1992

Prognostic association of YB-1 expression in breast cancers: a matter of antibody.

artículo científico publicado en 2011

Protein composition of catalytically active human telomerase from immortal cells

artículo científico publicado en 2007

Protein kinase C-alpha is multiply phosphorylated in response to phorbol ester stimulation of PC12 cells

artículo científico publicado en 1996

Protein phosphorylation is required for endocytosis in nerve terminals: potential role for the dephosphins dynamin I and synaptojanin, but not AP180 or amphiphysin

artículo científico publicado en 2001

Pyrimidine-Based Inhibitors of Dynamin I GTPase Activity: Competitive Inhibition at the Pleckstrin Homology Domain.

artículo científico publicado en 2016

Pyrimidyn compounds: dual-action small molecule pyrimidine-based dynamin inhibitors.

artículo científico publicado en 2013

Ral: mediator of membrane trafficking

artículo científico publicado en 2006

Rapid Analysis of Synaptic Vesicle Endocytosis in Synaptosomes

Rapid purification of native dynamin I and colorimetric GTPase assay

artículo científico publicado en 2005

Region and diagnosis-specific changes in synaptic proteins in schizophrenia and bipolar I disorder

artículo científico publicado en 2010

Repurposing molecular mechanisms of transmitter release: a new job for syndapin at the fusion pore. Focus on “Syndapin 3 modulates fusion pore expansion in mouse neuroendocrine chromaffin cells”

Role of dynamin in elongated cell migration in a 3D matrix.

artículo científico publicado en 2014

Role of the clathrin terminal domain in regulating coated pit dynamics revealed by small molecule inhibition

artículo científico publicado en 2011

SH3 Domains Differentially Stimulate Distinct Dynamin I Assembly Modes and G Domain Activity

artículo científico publicado en 2015

SIMAC (sequential elution from IMAC), a phosphoproteomics strategy for the rapid separation of monophosphorylated from multiply phosphorylated peptides

artículo científico publicado en 2007

Septin 3 (G-septin) is a developmentally regulated phosphoprotein enriched in presynaptic nerve terminals

scientific journal article

Septins and the Synapse

Simian hemorrhagic fever virus cell entry is dependent on CD163 and uses a clathrin-mediated endocytosis-like pathway

artículo científico publicado en 2014

Small molecule inhibition of Dynamin-dependent endocytosis targets multiple niche signals and impairs leukemia stem cells

artículo científico publicado en 2020

Small molecule inhibitors of dynamin I GTPase activity: development of dimeric tyrphostins

artículo científico publicado en 2005

Small molecules demonstrate the role of dynamin as a bi-directional regulator of the exocytosis fusion pore and vesicle release

artículo científico publicado en 2015

Sorting nexin 9 recruits clathrin heavy chain to the mitotic spindle for chromosome alignment and segregation

artículo científico publicado en 2013

Stanniocalcin 1 and 2 are secreted as phosphoproteins from human fibrosarcoma cells

scientific article published in 2000

Steroids from an Australian sponge Psammoclema sp.

artículo científico publicado en 2009

Strategies to enable large-scale proteomics for reproducible research

scientific article published on 30 July 2020

Styryl dye-based synaptic vesicle recycling assay in cultured cerebellar granule neurons

artículo científico publicado en 2008

Superfluous role of mammalian septins 3 and 5 in neuronal development and synaptic transmission

artículo científico publicado en 2008

Synapsin I-associated phosphatidylinositol 3-kinase mediates synaptic vesicle delivery to the readily releasable pool

artículo científico publicado en 2003

Syndapin I and endophilin I bind overlapping proline-rich regions of dynamin I: role in synaptic vesicle endocytosis

scientific journal article

Syndapin I is the phosphorylation-regulated dynamin I partner in synaptic vesicle endocytosis

artículo científico publicado en 2006

Syndapin--a membrane remodelling and endocytic F-BAR protein

artículo científico publicado en 2013

Synthesis and protein binding studies of a peptide fragment of clathrin assembly protein AP180 bearing an O-linked β-N-acetylglucosaminyl-6-phosphate modification

artículo científico publicado en 2012

Synthesis of Dynole 34-2, Dynole 2-24 and Dyngo 4a for investigating dynamin GTPase

Synthesis of the Pitstop family of clathrin inhibitors

Targeting Glioma Stem Cells by Functional Inhibition of Dynamin 2: A Novel Treatment Strategy for Glioblastoma

artículo científico publicado en 2019

Targeting membrane trafficking in infection prophylaxis: dynamin inhibitors

artículo científico publicado en 2012

Telomerase Recognizes G-Quadruplex and Linear DNA as Distinct Substrates†

artículo científico publicado en 2007

The Binding of Syndapin SH3 Domain to Dynamin Proline-rich Domain Involves Short and Long Distance Elements

artículo científico publicado en 2016

The Clathrin-dependent Spindle Proteome

artículo científico

The Impact of Commonly Used Alkylating Agents on Artifactual Peptide Modification

artículo científico publicado en 2017

The Rhodadyns, a New Class of Small Molecule Inhibitors of Dynamin GTPase Activity

artículo científico publicado en 2012

The actin-binding and bundling protein, EPLIN, is required for cytokinesis

artículo científico publicado en 2009

The dynamin inhibitors MiTMAB and OcTMAB induce cytokinesis failure and inhibit cell proliferation in human cancer cells

artículo científico publicado en 2010

The extracellular domain of the growth hormone receptor interacts with coactivator activator to promote cell proliferation

artículo científico publicado en 2008

The in vitro phosphorylation of actin from rat cerebral cortex

artículo científico publicado en 1983

The in vivo phosphorylation and glycosylation of human insulin-like growth factor-binding protein-5.

artículo científico publicado en 2007

The in vivo phosphorylation sites in multiple isoforms of amphiphysin I from rat brain nerve terminals

artículo científico publicado en 2008

The in vivo phosphorylation sites of rat brain dynamin I.

artículo científico publicado en 2007

The molecular pathology of amyloid deposition in Alzheimer's disease

artículo científico publicado el 1 de enero de 1991

The pathogenesis of ACTA1-related congenital fiber type disproportion

artículo científico publicado en 2007

The phospho-dependent dynamin-syndapin interaction triggers activity-dependent bulk endocytosis of synaptic vesicles

artículo científico publicado en 2009

The phosphorylation of p25/TPPP by LIM kinase 1 inhibits its ability to assemble microtubules

artículo científico publicado en 2007

The pthaladyns: GTP competitive inhibitors of dynamin I and II GTPase derived from virtual screening

artículo científico publicado en 2010

The role of protein kinase C and its neuronal substrates dephosphin, B-50, and MARCKS in neurotransmitter release

artículo científico publicado el 1 de enero de 1991

The small GTPases Rab5 and RalA regulate intracellular traffic of P-glycoprotein

artículo científico publicado en 2007

The temporal profile of activity-dependent presynaptic phospho-signalling reveals long-lasting patterns of poststimulus regulation

artículo científico publicado en 2019

Two Mechanisms of Synaptic Vesicle Recycling in Rat Brain Nerve Terminals

artículo científico publicado en 2000

Two fractions enriched for striatal synaptosomes isolated by percoll gradient centrifugation: synaptosome morphology, dopamine and serotonin receptor distribution, and adenylate cyclase activity

artículo científico publicado en 1989

Unique phosphorylation of protein kinase C-alpha in PC12 cells induces resistance to translocation and down-regulation

artículo científico publicado en 1996