Lista de obras - Maria Sibilia - Dominio Público Uruguay

A strain-independent postnatal neurodegeneration in mice lacking the EGF receptor

artículo científico publicado en 1998

ADAM17 is required for EGF-R-induced intestinal tumors via IL-6 trans-signaling.

artículo científico publicado en 2018

Afatinib restrains K-RAS–driven lung tumorigenesis

artículo científico publicado en 2018

Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation

artículo científico publicado en 1999

Amphiregulin enhances regulatory T cell-suppressive function via the epidermal growth factor receptor.

artículo científico publicado en 2013

Autocrine VEGF signaling synergizes with EGFR in tumor cells to promote epithelial cancer development

artículo científico publicado en 2010

Autophagy regulation in pancreatic acinar cells is independent of epidermal growth factor receptor signaling

artículo científico publicado en 2014

BRAF and MEK inhibitors increase PD1-positive melanoma cells leading to a potential lymphocyte-independent synergism with anti-PD1 antibody.

artículo científico publicado en 2018

Bacterial ghosts as adjuvant to oxaliplatin chemotherapy in colorectal carcinomatosis

artículo científico publicado en 2018

CCL7 contributes to the TNF-alpha-dependent inflammation of lesional psoriatic skin

artículo científico publicado en 2015

Consequences of epidermal growth factor receptor (ErbB1) loss for vascular smooth muscle cells from mice with targeted deletion of ErbB1.

artículo científico publicado en 2011

Consequences of postnatal vascular smooth muscle EGFR deletion on acute angiotensin II action

artículo científico publicado en 2015

Covalent Dimerization of Interleukin-Like Epithelial-to-Mesenchymal Transition (EMT) Inducer (ILEI) Facilitates EMT, Invasion and Late Aspects of Metastasis

artículo científico

Defective angiogenesis delays thrombus resolution: a potential pathogenetic mechanism underlying chronic thromboembolic pulmonary hypertension

artículo científico publicado en 2014

Differential utilization and localization of ErbB receptor tyrosine kinases in skin compared to normal and malignant keratinocytes

artículo científico publicado en 2001

Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telencephalon

artículo científico publicado en 1999

Divergent roles of HDAC1 and HDAC2 in the regulation of epidermal development and tumorigenesis

artículo científico publicado en 2013

EGF receptor is required for KRAS-induced pancreatic tumorigenesis

scientific journal article

EGF receptor signaling is essential for k-ras oncogene-driven pancreatic ductal adenocarcinoma

artículo científico publicado en 2012

EGFR Signaling in Liver Diseases

artículo científico publicado en 2016

EGFR controls bone development by negatively regulating mTOR-signaling during osteoblast differentiation.

artículo científico publicado en 2018

EGFR has a tumour-promoting role in liver macrophages during hepatocellular carcinoma formation

artículo científico publicado en 2014

EGFR in Tumor-Associated Myeloid Cells Promotes Development of Colorectal Cancer in Mice and Associates With Outcomes of Patients

artículo científico publicado en 2017

EGFR inhibitors erlotinib and lapatinib ameliorate epidermal blistering in pemphigus vulgaris in a non-linear, V-shaped relationship

artículo científico publicado en 2014

EGFR is required for FOS-dependent bone tumor development via RSK2/CREB signaling

artículo científico publicado en 2018

EWS-FLI1 perturbs MRTFB/YAP-1/TEAD target gene regulation inhibiting cytoskeletal autoregulatory feedback in Ewing sarcoma

artículo científico publicado en 2017

Early embryonic lethality of mice lacking the essential protein SNEV

artículo científico publicado en 2007

Ectodomain shedding of EGFR ligands and TNFR1 dictates hepatocyte apoptosis during fulminant hepatitis in mice

artículo científico publicado en 2010

Effects of Depilation Methods on Imiquimod-Induced Skin Inflammation in Mice

scientific article published on 30 September 2016

Effects of Imiquimod on Hair Follicle Stem Cells and Hair Cycle Progression

artículo científico publicado en 2016

Epidermal EGFR controls cutaneous host defense and prevents inflammation

artículo científico publicado en 2013

Epidermal Growth Factor Receptor Expression Licenses Type-2 Helper T Cells to Function in a T Cell Receptor-Independent Fashion

artículo científico publicado en 2017

Epidermal autonomous VEGFA/Flt1/Nrp1 functions mediate psoriasis-like disease

artículo científico publicado en 2020

Epidermal growth factor receptor signaling synergizes with Hedgehog/GLI in oncogenic transformation via activation of the MEK/ERK/JUN pathway

artículo científico publicado en 2009

Epidermal growth factor signaling protects from cholestatic liver injury and fibrosis

artículo científico publicado en 2016

Evidence That Cingulin Regulates Endothelial Barrier Function In Vitro and In Vivo

artículo científico publicado en 2016

Feasibility of personalized treatment concepts in gastrointestinal malignancies: Sub-group results of prospective clinical phase II trial EXACT

article published in 2018

Functions of c-Jun in liver and heart development

scientific journal article

Guidelines for vaccination of immunocompromised individuals

artículo científico publicado en 2016

Hair eruption initiates and commensal skin microbiota aggravate adverse events of anti-EGFR therapy

artículo científico publicado en 2019

Haploinsufficiency of senescence evasion factor causes defects of hematopoietic stem cells functions

artículo científico publicado en 2008

Hedgehog-EGFR cooperation response genes determine the oncogenic phenotype of basal cell carcinoma and tumour-initiating pancreatic cancer cells

artículo científico publicado en 2012

Hepatocyte-specific deletion of EGFR in mice reduces hepatic Abcg2 transport activity measured with [(11)C]erlotinib and positron emission tomography

artículo científico

High-Affinity IgE Receptors on Dendritic Cells Exacerbate Th2-Dependent Inflammation

artículo científico publicado en 2011

How imiquimod licenses plasmacytoid dendritic cells to kill tumors

artículo científico publicado en 2012

Identification and characterization of pDC-like cells in normal mouse skin and melanomas treated with imiquimod

artículo científico publicado en 2004

Imiquimod clears tumors in mice independent of adaptive immunity by converting pDCs into tumor-killing effector cells

artículo científico publicado en 2012

Impaired neural stem cell expansion and hypersensitivity to epileptic seizures in mice lacking the EGFR in the brain

scientific article published on 04 August 2018

Impaired postnatal hepatocyte proliferation and liver regeneration in mice lacking c-jun in the liver

artículo científico publicado en 2002

Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling

artículo científico publicado en 2018

Loss of epidermal growth factor receptor in vascular smooth muscle cells and cardiomyocytes causes arterial hypotension and cardiac hypertrophy

artículo científico publicado en 2012

Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability

artículo científico publicado en 2001

Mechanisms underlying skin disorders induced by EGFR inhibitors

artículo científico publicado en 2015

Methods to study MAP kinase signalling in the central nervous system.

artículo científico publicado en 2010

Mice humanised for the EGF receptor display hypomorphic phenotypes in skin, bone and heart

artículo científico publicado en 2003

Moderate inappropriately high aldosterone/NaCl constellation in mice: cardiovascular effects and the role of cardiovascular epidermal growth factor receptor

artículo científico publicado en 2014

Molecular oncology in lung cancer – between biomarkers and clinical application. Relevance of the Ras–Raf–MEK–ERK pathway

Mouse Models of Receptor Tyrosine Kinases

Mouse models of nonmelanoma skin cancer

artículo científico publicado en 2015

Neuronal survival depends on EGFR signaling in cortical but not midbrain astrocytes

artículo científico publicado en 2006

Oncogenic transformation by ras and fos is mediated by c-Jun N-terminal phosphorylation

artículo científico publicado en 2000

Osteopontin-deficient progenitor cells display enhanced differentiation to adipocytes

artículo científico publicado en 2018

Qualitative and quantitative re-evaluation of epidermal growth factor-ErbB1 action on developing midbrain dopaminergic neurons in vivo and in vitro: target-derived neurotrophic signaling (Part 1).

artículo científico publicado en 2011

RNA editing of Filamin A pre-mRNA regulates vascular contraction and diastolic blood pressure

artículo científico publicado en 2018

Raf-1 addiction in Ras-induced skin carcinogenesis

artículo científico publicado en 2009

Requirement of Stat3 Signaling in the Postnatal Development of Thymic Medullary Epithelial Cells

artículo científico publicado en 2016

SNEV(Prp19/PSO4) deficiency increases PUVA-induced senescence in mouse skin

artículo científico publicado en 2015

Sequential cooperation of CD2 and CD48 in the buildup of the early TCR signalosome

artículo científico publicado en 2009

Skin Inflammation Is Not Sufficient to Break Tolerance Induced against a Novel Antigen

artículo científico publicado en 2009

Specific roles for dendritic cell subsets during initiation and progression of psoriasis

artículo científico publicado en 2014

Strain-dependent epithelial defects in mice lacking the EGF receptor

artículo científico publicado en 1995

TNFalpha shedding and epidermal inflammation are controlled by Jun proteins

artículo científico publicado en 2009

TUSC3 loss alters the ER stress response and accelerates prostate cancer growth in vivo

artículo científico publicado en 2014

The AP-1 transcription factors c-Jun and JunB are essential for CD8α conventional dendritic cell identity

artículo científico publicado en 2021

The EGF receptor is required for efficient liver regeneration

artículo científico publicado en 2007

The EGF receptor provides an essential survival signal for SOS-dependent skin tumor development

artículo científico publicado en 2000

The EGFR network in bone biology and pathology

scientific article published on 12 October 2009

The cytoplasmic tail of CD45 is released from activated phagocytes and can act as an inhibitory messenger for T cells

artículo científico publicado en 2008

The epidermal growth factor receptor: from development to tumorigenesis

artículo científico publicado en 2007

The protein tyrosine kinase Tec regulates mast cell function

artículo científico publicado en 2009

Transgenic animals

c-Jun regulates eyelid closure and skin tumor development through EGFR signaling

artículo científico publicado en 2003

hVps37A Status affects prognosis and cetuximab sensitivity in ovarian cancer

artículo científico publicado en 2011

Lista de obras de Maria Sibilia

A strain-independent postnatal neurodegeneration in mice lacking the EGF receptor

ADAM17 is required for EGF-R-induced intestinal tumors via IL-6 trans-signaling.

Afatinib restrains K-RAS–driven lung tumorigenesis

Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation

Amphiregulin enhances regulatory T cell-suppressive function via the epidermal growth factor receptor.

Autocrine VEGF signaling synergizes with EGFR in tumor cells to promote epithelial cancer development

Autophagy regulation in pancreatic acinar cells is independent of epidermal growth factor receptor signaling

BRAF and MEK inhibitors increase PD1-positive melanoma cells leading to a potential lymphocyte-independent synergism with anti-PD1 antibody.

Bacterial ghosts as adjuvant to oxaliplatin chemotherapy in colorectal carcinomatosis

CCL7 contributes to the TNF-alpha-dependent inflammation of lesional psoriatic skin

Consequences of epidermal growth factor receptor (ErbB1) loss for vascular smooth muscle cells from mice with targeted deletion of ErbB1.

Consequences of postnatal vascular smooth muscle EGFR deletion on acute angiotensin II action

Covalent Dimerization of Interleukin-Like Epithelial-to-Mesenchymal Transition (EMT) Inducer (ILEI) Facilitates EMT, Invasion and Late Aspects of Metastasis

Defective angiogenesis delays thrombus resolution: a potential pathogenetic mechanism underlying chronic thromboembolic pulmonary hypertension

Differential utilization and localization of ErbB receptor tyrosine kinases in skin compared to normal and malignant keratinocytes

Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telencephalon

Divergent roles of HDAC1 and HDAC2 in the regulation of epidermal development and tumorigenesis

EGF receptor is required for KRAS-induced pancreatic tumorigenesis

EGF receptor signaling is essential for k-ras oncogene-driven pancreatic ductal adenocarcinoma

EGFR Signaling in Liver Diseases

EGFR controls bone development by negatively regulating mTOR-signaling during osteoblast differentiation.

EGFR has a tumour-promoting role in liver macrophages during hepatocellular carcinoma formation

EGFR in Tumor-Associated Myeloid Cells Promotes Development of Colorectal Cancer in Mice and Associates With Outcomes of Patients

EGFR inhibitors erlotinib and lapatinib ameliorate epidermal blistering in pemphigus vulgaris in a non-linear, V-shaped relationship

EGFR is required for FOS-dependent bone tumor development via RSK2/CREB signaling

EWS-FLI1 perturbs MRTFB/YAP-1/TEAD target gene regulation inhibiting cytoskeletal autoregulatory feedback in Ewing sarcoma

Early embryonic lethality of mice lacking the essential protein SNEV

Ectodomain shedding of EGFR ligands and TNFR1 dictates hepatocyte apoptosis during fulminant hepatitis in mice

Effects of Depilation Methods on Imiquimod-Induced Skin Inflammation in Mice

Effects of Imiquimod on Hair Follicle Stem Cells and Hair Cycle Progression

Epidermal EGFR controls cutaneous host defense and prevents inflammation

Epidermal Growth Factor Receptor Expression Licenses Type-2 Helper T Cells to Function in a T Cell Receptor-Independent Fashion

Epidermal autonomous VEGFA/Flt1/Nrp1 functions mediate psoriasis-like disease

Epidermal growth factor receptor signaling synergizes with Hedgehog/GLI in oncogenic transformation via activation of the MEK/ERK/JUN pathway

Epidermal growth factor signaling protects from cholestatic liver injury and fibrosis

Evidence That Cingulin Regulates Endothelial Barrier Function In Vitro and In Vivo

Feasibility of personalized treatment concepts in gastrointestinal malignancies: Sub-group results of prospective clinical phase II trial EXACT

Functions of c-Jun in liver and heart development

Guidelines for vaccination of immunocompromised individuals

Hair eruption initiates and commensal skin microbiota aggravate adverse events of anti-EGFR therapy

Haploinsufficiency of senescence evasion factor causes defects of hematopoietic stem cells functions

Hedgehog-EGFR cooperation response genes determine the oncogenic phenotype of basal cell carcinoma and tumour-initiating pancreatic cancer cells

Hepatocyte-specific deletion of EGFR in mice reduces hepatic Abcg2 transport activity measured with [(11)C]erlotinib and positron emission tomography

High-Affinity IgE Receptors on Dendritic Cells Exacerbate Th2-Dependent Inflammation

How imiquimod licenses plasmacytoid dendritic cells to kill tumors

Identification and characterization of pDC-like cells in normal mouse skin and melanomas treated with imiquimod

Imiquimod clears tumors in mice independent of adaptive immunity by converting pDCs into tumor-killing effector cells

Impaired neural stem cell expansion and hypersensitivity to epileptic seizures in mice lacking the EGFR in the brain

Impaired postnatal hepatocyte proliferation and liver regeneration in mice lacking c-jun in the liver

Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling

Loss of epidermal growth factor receptor in vascular smooth muscle cells and cardiomyocytes causes arterial hypotension and cardiac hypertrophy

Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability

Mechanisms underlying skin disorders induced by EGFR inhibitors

Methods to study MAP kinase signalling in the central nervous system.

Mice humanised for the EGF receptor display hypomorphic phenotypes in skin, bone and heart

Moderate inappropriately high aldosterone/NaCl constellation in mice: cardiovascular effects and the role of cardiovascular epidermal growth factor receptor

Molecular oncology in lung cancer – between biomarkers and clinical application. Relevance of the Ras–Raf–MEK–ERK pathway

Mouse Models of Receptor Tyrosine Kinases

Mouse models of nonmelanoma skin cancer

Neuronal survival depends on EGFR signaling in cortical but not midbrain astrocytes

Oncogenic transformation by ras and fos is mediated by c-Jun N-terminal phosphorylation

Osteopontin-deficient progenitor cells display enhanced differentiation to adipocytes

Qualitative and quantitative re-evaluation of epidermal growth factor-ErbB1 action on developing midbrain dopaminergic neurons in vivo and in vitro: target-derived neurotrophic signaling (Part 1).

RNA editing of Filamin A pre-mRNA regulates vascular contraction and diastolic blood pressure

Raf-1 addiction in Ras-induced skin carcinogenesis

Requirement of Stat3 Signaling in the Postnatal Development of Thymic Medullary Epithelial Cells

SNEV(Prp19/PSO4) deficiency increases PUVA-induced senescence in mouse skin

Sequential cooperation of CD2 and CD48 in the buildup of the early TCR signalosome

Skin Inflammation Is Not Sufficient to Break Tolerance Induced against a Novel Antigen

Specific roles for dendritic cell subsets during initiation and progression of psoriasis

Strain-dependent epithelial defects in mice lacking the EGF receptor

TNFalpha shedding and epidermal inflammation are controlled by Jun proteins

TUSC3 loss alters the ER stress response and accelerates prostate cancer growth in vivo

The AP-1 transcription factors c-Jun and JunB are essential for CD8α conventional dendritic cell identity

The EGF receptor is required for efficient liver regeneration

The EGF receptor provides an essential survival signal for SOS-dependent skin tumor development

The EGFR network in bone biology and pathology

The cytoplasmic tail of CD45 is released from activated phagocytes and can act as an inhibitory messenger for T cells

The epidermal growth factor receptor: from development to tumorigenesis