Lista de obras - Stefan K. Bohlander - Dominio Público Uruguay

A method for the rapid sequence-independent amplification of microdissected chromosomal material

artículo científico publicado el 1 de agosto de 1992

A mutation in the 5'-UTR of IFITM5 creates an in-frame start codon and causes autosomal-dominant osteogenesis imperfecta type V with hyperplastic callus

artículo científico publicado en 2012

A novel ABL1 fusion to the SH2 containing inositol phosphatase-1 (SHIP1) in acute lymphoblastic leukemia (ALL)

artículo científico publicado en 2011

A novel fluorometric assay for aldo-keto reductase 1C3 predicts metabolic activation of the nitrogen mustard prodrug PR-104A in human leukaemia cells

artículo científico publicado en 2014

A novel role for Lef-1, a central transcription mediator of Wnt signaling, in leukemogenesis

artículo científico publicado en 2008

A t(1;9)(q23.3 approximately q25;q34) affecting the ABL1 gene in a biphenotypic leukemia.

artículo científico publicado en 2004

A t(6;12)(q23;p13) results in the fusion of ETV6 to a novel gene, STL, in a B-cell ALL cell line.

artículo científico publicado en 1997

A yeast artificial chromosome-based map of the region of chromosome 20 containing the diabetes-susceptibility gene, MODY1, and a myeloid leukemia related gene

artículo científico publicado en 1996

ABCs of genomics.

artículo científico publicado en 2013

AML1-ETO meets JAK2: clinical evidence for the two hit model of leukemogenesis from a myeloproliferative syndrome progressing to acute myeloid leukemia

artículo científico publicado en 2007

Activating FLT3 mutants show distinct gain-of-function phenotypes in vitro and a characteristic signaling pathway profile associated with prognosis in acute myeloid leukemia

artículo científico publicado en 2014

Activity of a heptad of transcription factors is associated with stem cell programs and clinical outcome in acute myeloid leukemia

artículo científico publicado en 2013

Acute myeloid leukemia is propagated by a leukemic stem cell with lymphoid characteristics in a mouse model of CALM/AF10-positive leukemia

artículo científico publicado en 2006

Acute myeloid leukemia with biallelic CEBPA gene mutations and normal karyotype represents a distinct genetic entity associated with a favorable clinical outcome

artículo científico

Age-dependent frequencies of NPM1 mutations and FLT3-ITD in patients with normal karyotype AML (NK-AML).

artículo científico publicado en 2011

Age-specific differences in oncogenic pathway dysregulation and anthracycline sensitivity in patients with acute myeloid leukemia

artículo científico publicado en 2009

Allelic Imbalance of Recurrently Mutated Genes in Acute Myeloid Leukaemia

artículo científico publicado en 2019

Altered methylation pattern of the G6 PD promoter in Rett syndrome.

artículo científico publicado en 2002

An 86-probe-set gene-expression signature predicts survival in cytogenetically normal acute myeloid leukemia

artículo científico publicado en 2008

An eight-gene expression signature for the prediction of survival and time to treatment in chronic lymphocytic leukemia

artículo científico publicado en 2011

Association of Jacobsen syndrome and bipolar affective disorder in a patient with a de novo 11q terminal deletion

artículo científico publicado en 2006

BH3 mimetic ABT-737 neutralizes resistance to FLT3 inhibitor treatment mediated by FLT3-independent expression of BCL2 in primary AML blasts.

artículo científico publicado en 2007

Block of C/EBP alpha function by phosphorylation in acute myeloid leukemia with FLT3 activating mutations.

artículo científico publicado en 2006

C/EBPα regulated microRNA-34a targets E2F3 during granulopoiesis and is down-regulated in AML with CEBPA mutations

artículo científico publicado en 2010

CALM/AF10-positive leukemias show upregulation of genes involved in chromatin assembly and DNA repair processes and of genes adjacent to the breakpoint at 10p12.

artículo científico publicado en 2011

CBL exon 8/9 mutants activate the FLT3 pathway and cluster in core binding factor/11q deletion acute myeloid leukemia/myelodysplastic syndrome subtypes.

artículo científico publicado en 2009

CCAAT/enhancer-binding protein alpha (CEBPA) gene haploinsufficiency does not alter hematopoiesis or induce leukemia in Lck-CALM/AF10 transgenic mice.

artículo científico publicado en 2019

Cell-cycle regulator E2F1 and microRNA-223 comprise an autoregulatory negative feedback loop in acute myeloid leukemia

artículo científico publicado en 2010

Characterization of marker chromosomes by microdissection and fluorescence in situ hybridization

artículo científico publicado en 1994

Clinical presentation and differential splicing of SRSF2, U2AF1 and SF3B1 mutations in patients with acute myeloid leukemia

artículo científico publicado en 2020

Clinical remission following ascorbate treatment in a case of acute myeloid leukemia with mutations in TET2 and WT1

scientific article published on 02 October 2019

Codeletion of CDKN2 and MTAP genes in a subset of non-Hodgkin's lymphoma may be associated with histologic transformation from low-grade to diffuse large-cell lymphoma

scientific article published on 01 May 1998

Combined molecular and clinical prognostic index for relapse and survival in cytogenetically normal acute myeloid leukemia

artículo científico publicado en 2014

Construction of a 2.8-megabase yeast artificial chromosome contig and cloning of the human methylthioadenosine phosphorylase gene from the tumor suppressor region on 9p21 ⬇️

artículo científico publicado el 3 de julio de 1995

Correlation between the ETV6/CBFA2 (TEL/AML1) fusion gene and karyotypic abnormalities in children with B-cell precursor acute lymphoblastic leukemia

scientific article published on 01 October 1996

Defining the heterochromatin localization and repression domains of SALL1

artículo científico publicado en 2006

Detection of 9p deletions in leukemia cell lines by interphase fluorescence in situ hybridization with YAC-derived probes

scientific article published on 01 August 1995

Distinct microRNA expression profiles in acute myeloid leukemia with common translocations.

artículo científico publicado en 2008

Disturbing the histone code in leukemia: translocations and mutations affecting histone methyl transferases.

artículo científico publicado en 2014

Dose-dense induction with sequential high-dose cytarabine and mitoxantone (S-HAM) and pegfilgrastim results in a high efficacy and a short duration of critical neutropenia in de novo acute myeloid leukemia: a pilot study of the AMLCG.

artículo científico publicado en 2009

ERG expression is an independent prognostic factor and allows refined risk stratification in cytogenetically normal acute myeloid leukemia: a comprehensive analysis of ERG, MN1, and BAALC transcript levels using oligonucleotide microarrays

artículo científico publicado en 2009

ETV6: a versatile player in leukemogenesis.

artículo científico publicado en 2005

Ectopic expression of the homeobox gene Cdx2 is the transforming event in a mouse model of t(12;13)(p13;q12) acute myeloid leukemia

artículo científico publicado en 2004

Efficient identification of somatic mutations in acute myeloid leukaemia using whole exome sequencing of fingernail derived DNA as germline control

scientific article published in Scientific Reports

Elevated PIN1 expression by C/EBPalpha-p30 blocks C/EBPalpha-induced granulocytic differentiation through c-Jun in AML

artículo científico publicado en 2010

Eradication of Acute Myeloid Leukemia with FLT3 Ligand-Targeted miR-150 Nanoparticles.

artículo científico publicado en 2016

Exome sequencing identifies recurring FLT3 N676K mutations in core-binding factor leukemia.

artículo científico publicado en 2013

Expression analysis of genes located in the minimally deleted regions of 13q14 and 11q22-23 in chronic lymphocytic leukemia-unexpected expression pattern of the RHO GTPase activator ARHGAP20.

artículo científico publicado en 2011

FHL2 interacts with CALM and is highly expressed in acute erythroid leukemia.

artículo científico publicado en 2011

GATA2 zinc finger 1 mutations associated with biallelic CEBPA mutations define a unique genetic entity of acute myeloid leukemia

artículo científico

GPR56 identifies primary human acute myeloid leukemia cells with high repopulating potential in vivo.

artículo científico publicado en 2016

Gene expression profiles in acute myeloid leukemia with common translocations using SAGE.

artículo científico publicado en 2006

Genetic heterogeneity of cytogenetically normal AML with mutations of

artículo científico publicado en 2018

Genetic instability in inherited and sporadic leukemias.

artículo científico publicado en 2010

Genomic 5-hydroxymethylcytosine levels correlate with TET2 mutations and a distinct global gene expression pattern in secondary acute myeloid leukemia

artículo científico publicado en 2011

Genomic breakpoints and clinical features of MLL-TET1 rearrangement in acute leukemias.

artículo científico publicado en 2012

Global reduction of the epigenetic H3K79 methylation mark and increased chromosomal instability in CALM-AF10-positive leukemias.

artículo científico publicado en 2009

High expression of MZB1 predicts adverse prognosis in chronic lymphocytic leukemia, follicular lymphoma and diffuse large B-cell lymphoma and is associated with a unique gene expression signature

artículo científico publicado en 2012

High expression of lymphoid enhancer-binding factor-1 (LEF1) is a novel favorable prognostic factor in cytogenetically normal acute myeloid leukemia

artículo científico publicado en 2012

Identification and characterization of OSTL (RNF217) encoding a RING-IBR-RING protein adjacent to a translocation breakpoint involving ETV6 in childhood ALL.

artículo científico publicado en 2014

Identification of a 24-gene prognostic signature that improves the European LeukemiaNet risk classification of acute myeloid leukemia: an international collaborative study

artículo científico publicado en 2013

Identification of an ETV6-ABL2 fusion transcript in combination with an ETV6 point mutation in a T-cell acute lymphoblastic leukaemia cell line.

artículo científico publicado en 2002

Identification of pericentric inversion 12, inv(12)(p13.1q11), by fluorescence in situ hybridization in a patient with acute myeloid leukemia (AML-M6)

scientific article published on 01 September 1997

Identification of recurring tumor-specific somatic mutations in acute myeloid leukemia by transcriptome sequencing

artículo científico publicado en 2011

Inactivation of TP53 correlates with disease progression and low miR-34a expression in previously treated chronic lymphocytic leukemia patients.

artículo científico publicado en 2013

Inhibition of glutamate regulated calcium entry into leukemic megakaryoblasts reduces cell proliferation and supports differentiation.

artículo científico publicado en 2015

Interaction of the developmental regulator SALL1 with UBE2I and SUMO-1

artículo científico publicado en 2002

Isolated trisomy 13 defines a homogeneous AML subgroup with high frequency of mutations in spliceosome genes and poor prognosis

artículo científico

Localization of Y chromosome sequences and X chromosomal replication studies in XX males

artículo científico publicado en 1989

Mapping the diabetes polygene Idd3 on mouse chromosome 3 by use of novel congenic strains

artículo científico publicado en 1995

MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia

artículo científico publicado en 2007

Microdissection of the Y chromosome and fluorescence in situ hybridization analysis of the sex chromosomes of lake trout, Salvelinus namaycush

scientific article published on 01 June 1995

Molecular response assessment by quantitative real-time polymerase chain reaction after induction therapy in NPM1-mutated patients identifies those at high risk of relapse

artículo científico publicado en 2014

Mutations in SEC24D, encoding a component of the COPII machinery, cause a syndromic form of osteogenesis imperfecta

artículo científico publicado en 2015

NPM1 but not FLT3-ITD mutations predict early blast cell clearance and CR rate in patients with normal karyotype AML (NK-AML) or high-risk myelodysplastic syndrome (MDS).

artículo científico publicado en 2009

Overexpression of CDX2 perturbs HOX gene expression in murine progenitors depending on its N-terminal domain and is closely correlated with deregulated HOX gene expression in human acute myeloid leukemia

artículo científico publicado en 2007

Persistence of pre-leukemic clones during first remission and risk of relapse in acute myeloid leukemia.

artículo científico publicado en 2018

Preface to special issue: Acute myeloid leukemia-Genetics, stem cells, clonal evolution, and new therapies

artículo científico publicado en 2019

Proteomic identification of the MYST domain histone acetyltransferase TIP60 (HTATIP) as a co-activator of the myeloid transcription factor C/EBPalpha.

artículo científico publicado en 2008

RUNX1 mutations in cytogenetically normal acute myeloid leukemia are associated with a poor prognosis and up-regulation of lymphoid genes

artículo científico publicado en 2012

SRC is a signaling mediator in FLT3-ITD- but not in FLT3-TKD-positive AML.

artículo científico publicado en 2012

Somatic mutations in acute promyelocytic leukemia (APL) identified by exome sequencing

artículo científico publicado en 2011

Stem cell gene expression programs influence clinical outcome in human leukemia.

artículo científico publicado en 2011

The CALM and CALM/AF10 interactor CATS is a marker for proliferation

artículo científico publicado en 2008

The CATS (FAM64A) protein is a substrate of the Kinase Interacting Stathmin (KIS).

artículo científico publicado en 2013

The FLT3ITD mRNA level has a high prognostic impact in NPM1 mutated, but not in NPM1 unmutated, AML with a normal karyotype

artículo científico publicado en 2012

The MLL recombinome of acute leukemias in 2013.

artículo científico publicado en 2013

The cell of origin and the leukemia stem cell in acute myeloid leukemia

artículo científico publicado en 2019

The clathrin-binding domain of CALM and the OM-LZ domain of AF10 are sufficient to induce acute myeloid leukemia in mice ⬇️

artículo científico publicado el 17 de junio de 2011

The clinical mutatome of core binding factor leukemia

scientific article published on 02 January 2020

The interaction of ETV6 (TEL) and TIP60 requires a functional histone acetyltransferase domain in TIP60.

artículo científico publicado en 2007

The neuropeptide receptor calcitonin receptor-like (CALCRL) is a potential therapeutic target in acute myeloid leukemia

scientific article published on 10 June 2019

The radial nuclear positioning of genes correlates with features of megabase-sized chromatin domains.

artículo científico publicado en 2012

The vent-like homeobox gene VENTX promotes human myeloid differentiation and is highly expressed in acute myeloid leukemia ⬇️

artículo científico publicado en 2010

Unexpected variation in leukemia stem cell frequency and genetic heterogeneity in two murine leukemia models initiated by AML1/ETO9a and CALM/AF10

scientific article published on 04 December 2019

Validation and refinement of the revised 2017 European LeukemiaNet genetic risk stratification of acute myeloid leukemia

scientific article published on 30 March 2020

Whole-exome sequencing in adult ETP-ALL reveals a high rate of DNMT3A mutations

artículo científico publicado en 2013

[Diagnostics, classification and prognostic criteria of acute myeloid leukemia]

artículo científico publicado en 2007

[Modern leukemia diagnosis in adults].

artículo científico publicado en 2009

miR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemia

artículo científico publicado en 2016

Lista de obras de Stefan K. Bohlander

A method for the rapid sequence-independent amplification of microdissected chromosomal material

A mutation in the 5'-UTR of IFITM5 creates an in-frame start codon and causes autosomal-dominant osteogenesis imperfecta type V with hyperplastic callus

A novel ABL1 fusion to the SH2 containing inositol phosphatase-1 (SHIP1) in acute lymphoblastic leukemia (ALL)

A novel fluorometric assay for aldo-keto reductase 1C3 predicts metabolic activation of the nitrogen mustard prodrug PR-104A in human leukaemia cells

A novel role for Lef-1, a central transcription mediator of Wnt signaling, in leukemogenesis

A t(1;9)(q23.3 approximately q25;q34) affecting the ABL1 gene in a biphenotypic leukemia.

A t(6;12)(q23;p13) results in the fusion of ETV6 to a novel gene, STL, in a B-cell ALL cell line.

A yeast artificial chromosome-based map of the region of chromosome 20 containing the diabetes-susceptibility gene, MODY1, and a myeloid leukemia related gene

ABCs of genomics.

AML1-ETO meets JAK2: clinical evidence for the two hit model of leukemogenesis from a myeloproliferative syndrome progressing to acute myeloid leukemia

Activating FLT3 mutants show distinct gain-of-function phenotypes in vitro and a characteristic signaling pathway profile associated with prognosis in acute myeloid leukemia

Activity of a heptad of transcription factors is associated with stem cell programs and clinical outcome in acute myeloid leukemia

Acute myeloid leukemia is propagated by a leukemic stem cell with lymphoid characteristics in a mouse model of CALM/AF10-positive leukemia

Acute myeloid leukemia with biallelic CEBPA gene mutations and normal karyotype represents a distinct genetic entity associated with a favorable clinical outcome

Age-dependent frequencies of NPM1 mutations and FLT3-ITD in patients with normal karyotype AML (NK-AML).

Age-specific differences in oncogenic pathway dysregulation and anthracycline sensitivity in patients with acute myeloid leukemia

Allelic Imbalance of Recurrently Mutated Genes in Acute Myeloid Leukaemia

Altered methylation pattern of the G6 PD promoter in Rett syndrome.

An 86-probe-set gene-expression signature predicts survival in cytogenetically normal acute myeloid leukemia

An eight-gene expression signature for the prediction of survival and time to treatment in chronic lymphocytic leukemia

Association of Jacobsen syndrome and bipolar affective disorder in a patient with a de novo 11q terminal deletion

BH3 mimetic ABT-737 neutralizes resistance to FLT3 inhibitor treatment mediated by FLT3-independent expression of BCL2 in primary AML blasts.

Block of C/EBP alpha function by phosphorylation in acute myeloid leukemia with FLT3 activating mutations.

C/EBPα regulated microRNA-34a targets E2F3 during granulopoiesis and is down-regulated in AML with CEBPA mutations

CALM/AF10-positive leukemias show upregulation of genes involved in chromatin assembly and DNA repair processes and of genes adjacent to the breakpoint at 10p12.

CBL exon 8/9 mutants activate the FLT3 pathway and cluster in core binding factor/11q deletion acute myeloid leukemia/myelodysplastic syndrome subtypes.

CCAAT/enhancer-binding protein alpha (CEBPA) gene haploinsufficiency does not alter hematopoiesis or induce leukemia in Lck-CALM/AF10 transgenic mice.

Cell-cycle regulator E2F1 and microRNA-223 comprise an autoregulatory negative feedback loop in acute myeloid leukemia

Characterization of marker chromosomes by microdissection and fluorescence in situ hybridization

Clinical presentation and differential splicing of SRSF2, U2AF1 and SF3B1 mutations in patients with acute myeloid leukemia

Clinical remission following ascorbate treatment in a case of acute myeloid leukemia with mutations in TET2 and WT1

Codeletion of CDKN2 and MTAP genes in a subset of non-Hodgkin's lymphoma may be associated with histologic transformation from low-grade to diffuse large-cell lymphoma

Combined molecular and clinical prognostic index for relapse and survival in cytogenetically normal acute myeloid leukemia

Construction of a 2.8-megabase yeast artificial chromosome contig and cloning of the human methylthioadenosine phosphorylase gene from the tumor suppressor region on 9p21 ⬇️

Correlation between the ETV6/CBFA2 (TEL/AML1) fusion gene and karyotypic abnormalities in children with B-cell precursor acute lymphoblastic leukemia

Defining the heterochromatin localization and repression domains of SALL1

Detection of 9p deletions in leukemia cell lines by interphase fluorescence in situ hybridization with YAC-derived probes

Distinct microRNA expression profiles in acute myeloid leukemia with common translocations.

Disturbing the histone code in leukemia: translocations and mutations affecting histone methyl transferases.

Dose-dense induction with sequential high-dose cytarabine and mitoxantone (S-HAM) and pegfilgrastim results in a high efficacy and a short duration of critical neutropenia in de novo acute myeloid leukemia: a pilot study of the AMLCG.

ERG expression is an independent prognostic factor and allows refined risk stratification in cytogenetically normal acute myeloid leukemia: a comprehensive analysis of ERG, MN1, and BAALC transcript levels using oligonucleotide microarrays

ETV6: a versatile player in leukemogenesis.

Ectopic expression of the homeobox gene Cdx2 is the transforming event in a mouse model of t(12;13)(p13;q12) acute myeloid leukemia

Efficient identification of somatic mutations in acute myeloid leukaemia using whole exome sequencing of fingernail derived DNA as germline control

Elevated PIN1 expression by C/EBPalpha-p30 blocks C/EBPalpha-induced granulocytic differentiation through c-Jun in AML

Eradication of Acute Myeloid Leukemia with FLT3 Ligand-Targeted miR-150 Nanoparticles.

Exome sequencing identifies recurring FLT3 N676K mutations in core-binding factor leukemia.

Expression analysis of genes located in the minimally deleted regions of 13q14 and 11q22-23 in chronic lymphocytic leukemia-unexpected expression pattern of the RHO GTPase activator ARHGAP20.

FHL2 interacts with CALM and is highly expressed in acute erythroid leukemia.

GATA2 zinc finger 1 mutations associated with biallelic CEBPA mutations define a unique genetic entity of acute myeloid leukemia

GPR56 identifies primary human acute myeloid leukemia cells with high repopulating potential in vivo.

Gene expression profiles in acute myeloid leukemia with common translocations using SAGE.

Genetic heterogeneity of cytogenetically normal AML with mutations of

Genetic instability in inherited and sporadic leukemias.

Genomic 5-hydroxymethylcytosine levels correlate with TET2 mutations and a distinct global gene expression pattern in secondary acute myeloid leukemia

Genomic breakpoints and clinical features of MLL-TET1 rearrangement in acute leukemias.

Global reduction of the epigenetic H3K79 methylation mark and increased chromosomal instability in CALM-AF10-positive leukemias.

High expression of MZB1 predicts adverse prognosis in chronic lymphocytic leukemia, follicular lymphoma and diffuse large B-cell lymphoma and is associated with a unique gene expression signature

High expression of lymphoid enhancer-binding factor-1 (LEF1) is a novel favorable prognostic factor in cytogenetically normal acute myeloid leukemia

Identification and characterization of OSTL (RNF217) encoding a RING-IBR-RING protein adjacent to a translocation breakpoint involving ETV6 in childhood ALL.

Identification of a 24-gene prognostic signature that improves the European LeukemiaNet risk classification of acute myeloid leukemia: an international collaborative study

Identification of an ETV6-ABL2 fusion transcript in combination with an ETV6 point mutation in a T-cell acute lymphoblastic leukaemia cell line.

Identification of pericentric inversion 12, inv(12)(p13.1q11), by fluorescence in situ hybridization in a patient with acute myeloid leukemia (AML-M6)

Identification of recurring tumor-specific somatic mutations in acute myeloid leukemia by transcriptome sequencing

Inactivation of TP53 correlates with disease progression and low miR-34a expression in previously treated chronic lymphocytic leukemia patients.

Inhibition of glutamate regulated calcium entry into leukemic megakaryoblasts reduces cell proliferation and supports differentiation.

Interaction of the developmental regulator SALL1 with UBE2I and SUMO-1

Isolated trisomy 13 defines a homogeneous AML subgroup with high frequency of mutations in spliceosome genes and poor prognosis

Localization of Y chromosome sequences and X chromosomal replication studies in XX males

Mapping the diabetes polygene Idd3 on mouse chromosome 3 by use of novel congenic strains

MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia

Microdissection of the Y chromosome and fluorescence in situ hybridization analysis of the sex chromosomes of lake trout, Salvelinus namaycush

Molecular response assessment by quantitative real-time polymerase chain reaction after induction therapy in NPM1-mutated patients identifies those at high risk of relapse

Mutations in SEC24D, encoding a component of the COPII machinery, cause a syndromic form of osteogenesis imperfecta

NPM1 but not FLT3-ITD mutations predict early blast cell clearance and CR rate in patients with normal karyotype AML (NK-AML) or high-risk myelodysplastic syndrome (MDS).

Overexpression of CDX2 perturbs HOX gene expression in murine progenitors depending on its N-terminal domain and is closely correlated with deregulated HOX gene expression in human acute myeloid leukemia

Persistence of pre-leukemic clones during first remission and risk of relapse in acute myeloid leukemia.

Preface to special issue: Acute myeloid leukemia-Genetics, stem cells, clonal evolution, and new therapies

Proteomic identification of the MYST domain histone acetyltransferase TIP60 (HTATIP) as a co-activator of the myeloid transcription factor C/EBPalpha.