Lista de obras - Nadine Rouphael - Dominio Público Uruguay

"Bazex syndromes": dissimilar entities named after the same father!

artículo científico publicado en 2002

2314. Burden of Respiratory Syncytial Virus (RSV) Infection Among Hospitalized Older Adults and Those with Underlying Chronic Obstructive Pulmonary Disease (COPD) or Congestive Heart Failure (CHF)

artículo científico publicado en 2019

2492. Clinical, Virologic, and Immunologic Characteristics of Zika Virus Infection in a Cohort of US Patients

scholarly article by Hana M El Sahly et al published November 2018 in Open Forum Infectious Diseases

2739. Comparison of Hemagglutination Antibody Inhibition (HAI) Titers Following Influenza Vaccination by Birth Cohort and Repeated Influenza Vaccination History

artículo científico publicado en 2019

A Painful Thorn in the Foot: A Case of Eumycetoma

artículo científico publicado en 2007

A Retrospective Chart Review on the Role of Suppressive Therapy in the Management of Spinal Infections Involving Hardware

artículo científico publicado en 2020

A real-time polymerase chain reaction for the detection of Streptococcus pneumoniae in blood using a mouse model: a potential new "gold standard".

artículo científico publicado en 2008

Acceptability of an inactivated influenza vaccine delivered by microneedle patch: Results from a phase I clinical trial of safety, reactogenicity, and immunogenicity

scientific article published on 10 August 2020

Adjuvanted H5N1 influenza vaccine enhances both cross-reactive memory B cell and strain-specific naive B cell responses in humans

artículo científico publicado en 2020

Alterations in the Human Plasma Lipidome in Response to Tularemia Vaccination

artículo científico publicado en 2020

An mRNA Vaccine against SARS-CoV-2 - Preliminary Report

artículo científico publicado en 2020

Antibiotics-Driven Gut Microbiome Perturbation Alters Immunity to Vaccines in Humans

artículo científico publicado en 2019

Antibody Persistence through 6 Months after the Second Dose of mRNA-1273 Vaccine for Covid-19

scholarly article by Nicole Doria-Rose published in 2021

Aspergillus endocarditis: a review of the literature.

artículo científico publicado en 2010

Baricitinib plus Remdesivir for Hospitalized Adults with Covid-19

scientific article published on 11 December 2020

Baseline Levels of Influenza-Specific B Cells and T Cell Responses Modulate Human Immune Responses to Swine Variant Influenza A/H3N2 Vaccine

scientific article published on 13 March 2020

Biphasic Zika Illness With Rash and Joint Pain

artículo científico

Breadth and functionality of varicella zoster virus glycoprotein-specific antibodies identified after Zostavax vaccination in humans.

artículo científico publicado en 2018

Broadly reactive human CD8 T cells that recognize an epitope conserved between VZV, HSV and EBV.

artículo científico publicado en 2014

COVID-19 serology at population scale: SARS-CoV-2-specific antibody responses in saliva

artículo científico publicado en 2020

COVID-19 serology at population scale: SARS-CoV-2-specific antibody responses in saliva

scientific article published on 16 October 2020

Cardiac manifestations of parasitic infections part 1: overview and immunopathogenesis.

artículo científico publicado en 2007

Cardiac manifestations of parasitic infections part 3: pericardial and miscellaneous cardiopulmonary manifestations

artículo científico publicado en 2007

Cardiac manifestations of parasitic infections. Part 2: Parasitic myocardial disease. ⬇️

artículo científico publicado en 2007

Case report: atypical Lemierre's disease secondary to Porphyromonas asaccharolytica.

artículo científico publicado en 2009

Characterization of flares in patients with systemic lupus erythematosus: Comment on the article by Ho et al

scholarly article by Ayoub N et al published February 2003 in Arthritis and Rheumatism

Clinical, Virologic, and Immunologic Characteristics of Zika Virus Infection in a Cohort of US Patients: Prolonged RNA Detection in Whole Blood

article

Clostridium difficile–associated diarrhea: an emerging threat to pregnant women

article by Nadine Rouphael et al published June 2008 in American Journal of Obstetrics and Gynecology

Comparison of lyophilized versus liquid modified vaccinia Ankara (MVA) formulations and subcutaneous versus intradermal routes of administration in healthy vaccinia-naïve subjects

artículo científico publicado en 2015

Cytomegalovirus Prostatitis in a Heart Transplant Recipient

artículo científico publicado en 2011

DNA priming and gp120 boosting induces HIV-specific antibodies in a randomized clinical trial

artículo científico publicado en 2019

Development and optimization of a Zika virus antibody-dependent cell-mediated cytotoxicity (ADCC) assay

artículo científico publicado en 2020

Development of a Rapid Focus Reduction Neutralization Test Assay for Measuring SARS-CoV-2 Neutralizing Antibodies

artículo científico publicado en 2020

Diagnostic Importance of Hyphae on Heart Valve Tissue in Histoplasma Endocarditis and Treatment With Isavuconazole

artículo científico publicado en 2017

Dissolvable Microneedle Patches to Enable Increased Access to Vaccines against SARS-CoV-2 and Future Pandemic Outbreaks

artículo científico publicado en 2021

Durability of Responses after SARS-CoV-2 mRNA-1273 Vaccination

artículo científico publicado en 2020

Durability of mRNA-1273 vaccine–induced antibodies against SARS-CoV-2 variants

artículo científico publicado en 2021

Duration of Cellular and Humoral Responses after Quadrivalent Human Papillomavirus Vaccination in Healthy Female Adults with or without Prior Type 16 and/or 18 Exposure

artículo científico publicado en 2020

Effect of Concomitant Antibiotic and Vaccine Administration on Serologic Responses to Rotavirus Vaccine

artículo científico publicado en 2019

Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine

artículo científico publicado en 2020

Evaluation of serum bactericidal antibody assays for Haemophilus influenzae serotype a.

artículo científico publicado en 2010

Evolution

artículo científico publicado en 2008

First-in-Human Evaluation of the Safety and Immunogenicity of a Recombinant Vesicular Stomatitis Virus Human Immunodeficiency Virus-1 gag Vaccine (HVTN 090).

artículo científico publicado en 2015

Fusarium falciforme vertebral abscess and osteomyelitis: case report and molecular classification

artículo científico publicado en 2011

Hepatitis B reverse seroconversion in HIV-positive patients: case series and review of the literature

artículo científico publicado en 2007

Hirsutism

artículo científico publicado en 2002

Immunogenicity and safety of four different dosing regimens of anthrax vaccine adsorbed for post-exposure prophylaxis for anthrax in adults

artículo científico publicado en 2014

Immunogenicity and safety of varying dosages of a monovalent 2009 H1N1 influenza vaccine given with and without AS03 adjuvant system in healthy adults and older persons

artículo científico publicado en 2012

Immunogenicity of avian influenza A/Anhui/01/2005(H5N1) vaccine with MF59 adjuvant: a randomized clinical trial

artículo científico

Immunomodulatory Low-Dose Whole-Lung Radiation for Patients with COVID-19-Related Pneumonia

artículo científico publicado en 2020

Infection and vaccine-induced antibody binding and neutralization of the B.1.351 SARS-CoV-2 variant

artículo científico publicado en 2021

Infections associated with haemophagocytic syndrome.

artículo científico publicado en 2007

Innate, T and B Cell Responses in Acute Human Zika Patients

artículo científico publicado en 2017

Is the BCG Vaccine an Answer to Future Pandemic Preparedness?

artículo científico publicado en 2022

Landscapes of binding antibody and T-cell responses to pox-protein HIV vaccines in Thais and South Africans

scientific article published on 30 January 2020

Metabolic Phenotypes of Response to Vaccination in Humans

artículo científico publicado en 2017

Microneedle patch for immunization of immunocompromised hosts

artículo científico publicado en 2017

Molecular signatures of antibody responses derived from a systems biology study of five human vaccines

artículo científico publicado en 2013

Neisseria meningitidis: biology, microbiology, and epidemiology.

artículo científico publicado en 2012

Occupational Exposure to the Ugandan Research Strain (MR766) of Zika Virus

artículo científico publicado en 2019

Pericarditis Associated With Acute Zika Virus Infection in a Returning Traveler

artículo científico publicado en 2017

Persistence of varicella zoster virus specific plasma cells in adult human bone marrow following childhood vaccination

artículo científico publicado en 2020

Phase II trial in adults of concurrent or sequential 2009 pandemic H1N1 and 2009-2010 seasonal trivalent influenza vaccinations

artículo científico publicado en 2014

Phase Ib Trial To Evaluate the Safety and Pharmacokinetics of Multiple Ascending Doses of Filociclovir (MBX-400, Cyclopropavir) in Healthy Volunteers

scientific article published on 23 August 2019

Phenotypes of disease severity in a cohort of hospitalized COVID-19 patients: Results from the IMPACC study

artículo científico publicado en 2022

Plasmablast, Memory B Cell, CD4+ T Cell, and Circulating Follicular Helper T Cell Responses to a Non-Replicating Modified Vaccinia Ankara Vaccine

artículo científico publicado en 2020

Pleural effusion in a patient with AIDS.

artículo científico publicado en 2008

Point-of-Use Mixing of Influenza H5N1 Vaccine and MF59 Adjuvant for Pandemic Vaccination Preparedness: Antibody Responses and Safety. A Phase 1 Clinical Trial

artículo científico publicado en 2014

Polymyxin B and doxycycline use in patients with multidrug-resistant Acinetobacter baumannii infections in the intensive care unit.

artículo científico publicado en 2006

Pre-Existing Dengue Immunity Drives a DENV-Biased Plasmablast Response in ZIKV-Infected Patient

article

Progress toward the global control of Neisseria meningitidis: 21st century vaccines, current guidelines, and challenges for future vaccine development.

artículo científico publicado en 2018

Proteomic Analysis of Human Immune Responses to Live-Attenuated Tularemia Vaccine

artículo científico publicado en 2020

Randomized clinical trial of a single versus a double dose of 13-valent pneumococcal conjugate vaccine in adults 55 through 74 years of age previously vaccinated with 23-valent pneumococcal polysaccharide vaccine

artículo científico publicado en 2017

Rapid Generation of Neutralizing Antibody Responses in COVID-19 Patients

artículo científico publicado en 2020

Rapid generation of neutralizing antibody responses in COVID-19 patients

artículo científico publicado en 2020

Reduced binding and neutralization of infection- and vaccine-induced antibodies to the B.1.351 (South African) SARS-CoV-2 variant

artículo científico publicado en 2021

Reply letter to "Fatal meningococcemia due to Neisseria meningitidis serogroup Y in a vaccinated child receiving eculizumab"

artículo científico publicado en 2018

Reply to "A refugee patient with meningococcal meningitis type B."

artículo científico publicado en 2018

Retrospective Study of Cryptococcal Meningitis With Elevated Minimum Inhibitory Concentration to Fluconazole in Immunocompromised Patients

artículo científico publicado en 2016

Safety and Immunogenicity of SARS-CoV-2 mRNA-1273 Vaccine in Older Adults

artículo científico publicado en 2020

Safety and Immunogenicity of a Recombinant Adenovirus Serotype 35-Vectored HIV-1 Vaccine in Adenovirus Serotype 5 Seronegative and Seropositive Individuals

artículo científico publicado en 2015

Safety and Immunogenicity of a Subvirion Monovalent Unadjuvanted Inactivated Influenza A(H3N2) Variant Vaccine in Healthy Persons ≥18 Years Old

artículo científico publicado en 2015

Safety and immunogenicity of a modified vaccinia Ankara vaccine using three immunization schedules and two modes of delivery: A randomized clinical non-inferiority trial

artículo científico

Safety and immunogenicity of a trivalent virus-like particle vaccine against western, eastern, and Venezuelan equine encephalitis viruses: a phase 1, open-label, dose-escalation, randomised clinical trial

artículo científico publicado en 2022

Safety, tolerability, and immunogenicity of two Zika virus DNA vaccine candidates in healthy adults: randomised, open-label, phase 1 clinical trials

artículo científico publicado en 2017

Sequence and vector shapes vaccine induced antibody effector functions in HIV vaccine trials

artículo científico publicado en 2021

Sequential Multiple Assignment Randomized Trials for COMparing Personalized Antibiotic StrategieS (SMART-COMPASS)

artículo científico publicado en 2019

Serological responses to an avian influenza A/H7N9 vaccine mixed at the point-of-use with MF59 adjuvant: a randomized clinical trial

artículo científico

Skin Ulcers Misdiagnosed as Pyoderma Gangrenosum

artículo científico publicado en 2003

Spectrum of CNS disease caused by rapidly growing mycobacteria.

artículo científico publicado en 2008

Strategies to increase responsiveness to hepatitis B vaccination in adults with HIV-1

artículo científico publicado en 2012

Streptococcus infantis, Streptococcus mitis, and Streptococcus oralis Strains With Highly Similar cps5 Loci and Antigenic Relatedness to Serotype 5 Pneumococci

artículo científico publicado en 2018

Streptococcus mitis Expressing Pneumococcal Serotype 1 Capsule

artículo científico publicado en 2018

Streptococcus pneumoniae colonization after introduction of 13-valent pneumococcal conjugate vaccine for US adults 65 years of age and older, 2015-2016

scholarly article by Jennifer Milucky et al published 14 February 2019 in Vaccine

Swimming with the Pigs: A Case of Severe Soft Tissue Infection during a Caribbean Vacation

artículo científico publicado en 2018

Systems Analysis of Immunity to Influenza Vaccination across Multiple Years and in Diverse Populations Reveals Shared Molecular Signatures

artículo científico publicado en 2015

Systems Biological Analysis of Immune Response to Influenza Vaccination

scientific article published on 09 March 2020

Systems Vaccinology for a Live Attenuated Tularemia Vaccine Reveals Unique Transcriptional Signatures That Predict Humoral and Cellular Immune Responses

artículo científico publicado en 2019

Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans

artículo científico publicado en 2020

Systems biology of vaccination in the elderly

artículo científico publicado en 2013

The Effect of Anticoagulants, Temperature, and Time on the Human Plasma Metabolome and Lipidome from Healthy Donors as Determined by Liquid Chromatography-Mass Spectrometry.

artículo científico publicado en 2019

The Effects of Imprinting and Repeated Seasonal Influenza Vaccination on Adaptive Immunity after Influenza Vaccination

artículo científico publicado en 2020

The Future of Flu: A Review of the Human Challenge Model and Systems Biology for Advancement of Influenza Vaccinology

scholarly article by Amy Caryn Sherman et al published 2019 in Frontiers in cellular and infection microbiology

The Role of Systems Vaccinology in Understanding the Immune Defects to Vaccination in Solid Organ Transplant Recipients

scientific article published on 25 November 2020

The development and kinetics of functional antibody-dependent cell-mediated cytotoxicity (ADCC) to SARS-CoV-2 spike protein

artículo científico publicado en 2021

The receptor binding domain of the viral spike protein is an immunodominant and highly specific target of antibodies in SARS-CoV-2 patients

scientific article published on 01 June 2020

The safety, immunogenicity, and acceptability of inactivated influenza vaccine delivered by microneedle patch (TIV-MNP 2015): a randomised, partly blinded, placebo-controlled, phase 1 trial.

artículo científico publicado en 2017

The single-cell epigenomic and transcriptional landscape of immunity to influenza vaccination

artículo científico

Transcriptomic and Metabolic Responses to a Live-Attenuated Francisella tularensis Vaccine

artículo científico publicado en 2020

Triplex Real-Time RT-PCR for Severe Acute Respiratory Syndrome Coronavirus 2

artículo científico publicado en 2020

Tularemia vaccine: Safety, reactogenicity, "Take" skin reactions, and antibody responses following vaccination with a new lot of the Francisella tularensis live vaccine strain - A phase 2 randomized clinical Trial

artículo científico publicado en 2017

Use of 2 pneumococcal common protein real-time polymerase chain reaction assays in healthy children colonized with Streptococcus pneumoniae.

artículo científico publicado en 2011

Vaccination strategies to prevent tuberculosis in the new millennium: from BCG to new vaccine candidates

artículo científico publicado en 2005

Variability in the Management of Adults with Pulmonary Nontuberculous Mycobacterial Disease

scientific article published on 21 March 2020

Varicella-Zoster Virus DNA in Blood After Administration of Herpes Zoster Vaccine

artículo científico publicado en 2018

Varicella-Zoster Virus-Specific Cellular Immune Responses to the Live Attenuated Zoster Vaccine in Young and Older Adults.

artículo científico publicado en 2017

Willingness to Participate in Vaccine-Related Clinical Trials among Older Adults

artículo científico publicado en 2018

Lista de obras de Nadine Rouphael

"Bazex syndromes": dissimilar entities named after the same father!

2314. Burden of Respiratory Syncytial Virus (RSV) Infection Among Hospitalized Older Adults and Those with Underlying Chronic Obstructive Pulmonary Disease (COPD) or Congestive Heart Failure (CHF)

2492. Clinical, Virologic, and Immunologic Characteristics of Zika Virus Infection in a Cohort of US Patients

2739. Comparison of Hemagglutination Antibody Inhibition (HAI) Titers Following Influenza Vaccination by Birth Cohort and Repeated Influenza Vaccination History

A Painful Thorn in the Foot: A Case of Eumycetoma

A Retrospective Chart Review on the Role of Suppressive Therapy in the Management of Spinal Infections Involving Hardware

A real-time polymerase chain reaction for the detection of Streptococcus pneumoniae in blood using a mouse model: a potential new "gold standard".

Acceptability of an inactivated influenza vaccine delivered by microneedle patch: Results from a phase I clinical trial of safety, reactogenicity, and immunogenicity

Adjuvanted H5N1 influenza vaccine enhances both cross-reactive memory B cell and strain-specific naive B cell responses in humans

Alterations in the Human Plasma Lipidome in Response to Tularemia Vaccination

An mRNA Vaccine against SARS-CoV-2 - Preliminary Report

Antibiotics-Driven Gut Microbiome Perturbation Alters Immunity to Vaccines in Humans

Antibody Persistence through 6 Months after the Second Dose of mRNA-1273 Vaccine for Covid-19

Aspergillus endocarditis: a review of the literature.

Baricitinib plus Remdesivir for Hospitalized Adults with Covid-19

Baseline Levels of Influenza-Specific B Cells and T Cell Responses Modulate Human Immune Responses to Swine Variant Influenza A/H3N2 Vaccine

Biphasic Zika Illness With Rash and Joint Pain

Breadth and functionality of varicella zoster virus glycoprotein-specific antibodies identified after Zostavax vaccination in humans.

Broadly reactive human CD8 T cells that recognize an epitope conserved between VZV, HSV and EBV.

COVID-19 serology at population scale: SARS-CoV-2-specific antibody responses in saliva

COVID-19 serology at population scale: SARS-CoV-2-specific antibody responses in saliva

Cardiac manifestations of parasitic infections part 1: overview and immunopathogenesis.

Cardiac manifestations of parasitic infections part 3: pericardial and miscellaneous cardiopulmonary manifestations

Cardiac manifestations of parasitic infections. Part 2: Parasitic myocardial disease. ⬇️

Case report: atypical Lemierre's disease secondary to Porphyromonas asaccharolytica.

Characterization of flares in patients with systemic lupus erythematosus: Comment on the article by Ho et al

Clinical, Virologic, and Immunologic Characteristics of Zika Virus Infection in a Cohort of US Patients: Prolonged RNA Detection in Whole Blood

Clostridium difficile–associated diarrhea: an emerging threat to pregnant women

Comparison of lyophilized versus liquid modified vaccinia Ankara (MVA) formulations and subcutaneous versus intradermal routes of administration in healthy vaccinia-naïve subjects

Cytomegalovirus Prostatitis in a Heart Transplant Recipient

DNA priming and gp120 boosting induces HIV-specific antibodies in a randomized clinical trial

Development and optimization of a Zika virus antibody-dependent cell-mediated cytotoxicity (ADCC) assay

Development of a Rapid Focus Reduction Neutralization Test Assay for Measuring SARS-CoV-2 Neutralizing Antibodies

Diagnostic Importance of Hyphae on Heart Valve Tissue in Histoplasma Endocarditis and Treatment With Isavuconazole

Dissolvable Microneedle Patches to Enable Increased Access to Vaccines against SARS-CoV-2 and Future Pandemic Outbreaks

Durability of Responses after SARS-CoV-2 mRNA-1273 Vaccination

Durability of mRNA-1273 vaccine–induced antibodies against SARS-CoV-2 variants

Duration of Cellular and Humoral Responses after Quadrivalent Human Papillomavirus Vaccination in Healthy Female Adults with or without Prior Type 16 and/or 18 Exposure

Effect of Concomitant Antibiotic and Vaccine Administration on Serologic Responses to Rotavirus Vaccine

Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine

Evaluation of serum bactericidal antibody assays for Haemophilus influenzae serotype a.

Evolution

First-in-Human Evaluation of the Safety and Immunogenicity of a Recombinant Vesicular Stomatitis Virus Human Immunodeficiency Virus-1 gag Vaccine (HVTN 090).

Fusarium falciforme vertebral abscess and osteomyelitis: case report and molecular classification

Hepatitis B reverse seroconversion in HIV-positive patients: case series and review of the literature

Hirsutism

Immunogenicity and safety of four different dosing regimens of anthrax vaccine adsorbed for post-exposure prophylaxis for anthrax in adults

Immunogenicity and safety of varying dosages of a monovalent 2009 H1N1 influenza vaccine given with and without AS03 adjuvant system in healthy adults and older persons

Immunogenicity of avian influenza A/Anhui/01/2005(H5N1) vaccine with MF59 adjuvant: a randomized clinical trial

Immunomodulatory Low-Dose Whole-Lung Radiation for Patients with COVID-19-Related Pneumonia

Infection and vaccine-induced antibody binding and neutralization of the B.1.351 SARS-CoV-2 variant

Infections associated with haemophagocytic syndrome.

Innate, T and B Cell Responses in Acute Human Zika Patients

Is the BCG Vaccine an Answer to Future Pandemic Preparedness?

Landscapes of binding antibody and T-cell responses to pox-protein HIV vaccines in Thais and South Africans

Metabolic Phenotypes of Response to Vaccination in Humans

Microneedle patch for immunization of immunocompromised hosts

Molecular signatures of antibody responses derived from a systems biology study of five human vaccines

Neisseria meningitidis: biology, microbiology, and epidemiology.

Occupational Exposure to the Ugandan Research Strain (MR766) of Zika Virus

Pericarditis Associated With Acute Zika Virus Infection in a Returning Traveler

Persistence of varicella zoster virus specific plasma cells in adult human bone marrow following childhood vaccination

Phase II trial in adults of concurrent or sequential 2009 pandemic H1N1 and 2009-2010 seasonal trivalent influenza vaccinations

Phase Ib Trial To Evaluate the Safety and Pharmacokinetics of Multiple Ascending Doses of Filociclovir (MBX-400, Cyclopropavir) in Healthy Volunteers

Phenotypes of disease severity in a cohort of hospitalized COVID-19 patients: Results from the IMPACC study

Plasmablast, Memory B Cell, CD4+ T Cell, and Circulating Follicular Helper T Cell Responses to a Non-Replicating Modified Vaccinia Ankara Vaccine

Pleural effusion in a patient with AIDS.

Point-of-Use Mixing of Influenza H5N1 Vaccine and MF59 Adjuvant for Pandemic Vaccination Preparedness: Antibody Responses and Safety. A Phase 1 Clinical Trial

Polymyxin B and doxycycline use in patients with multidrug-resistant Acinetobacter baumannii infections in the intensive care unit.

Pre-Existing Dengue Immunity Drives a DENV-Biased Plasmablast Response in ZIKV-Infected Patient

Progress toward the global control of Neisseria meningitidis: 21st century vaccines, current guidelines, and challenges for future vaccine development.

Proteomic Analysis of Human Immune Responses to Live-Attenuated Tularemia Vaccine

Randomized clinical trial of a single versus a double dose of 13-valent pneumococcal conjugate vaccine in adults 55 through 74 years of age previously vaccinated with 23-valent pneumococcal polysaccharide vaccine

Rapid Generation of Neutralizing Antibody Responses in COVID-19 Patients

Rapid generation of neutralizing antibody responses in COVID-19 patients

Reduced binding and neutralization of infection- and vaccine-induced antibodies to the B.1.351 (South African) SARS-CoV-2 variant

Reply letter to "Fatal meningococcemia due to Neisseria meningitidis serogroup Y in a vaccinated child receiving eculizumab"

Reply to "A refugee patient with meningococcal meningitis type B."

Retrospective Study of Cryptococcal Meningitis With Elevated Minimum Inhibitory Concentration to Fluconazole in Immunocompromised Patients

Randomized clinical trial of a single versus a double dose of 13-valent pneumococcal conjugate vaccine in adults 55 through 74 years of age previously vaccinated with 23-valent pneumococcal polysaccharide vaccine